• 제목/요약/키워드: personality gene

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Trends and Directions in Personality Genetic Studies

  • Kim, Han-Na;Kim, Hyung-Lae
    • Genomics & Informatics
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    • 제9권2호
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    • pp.45-51
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    • 2011
  • How personality forms and whether personality genes exist are long-studied questions. Various concepts and theories have been presented for centuries. Personality is a complex trait and is developed through the interaction of genes and the environment. Twin and family studies have found that there are critical genetic and environmental components in the inheritance of personality traits, and modern advances in genetics are making it possible to identify specific variants for personality traits. Although genes that were found in studies on personality have not provided replicable association between genetic and personality variability, more and more genetic variants associated with personality traits are being discovered. Here, we present the current state of the art on genetic research in the personality field and finally list several of the recently published research highlights. First, we briefly describe the commonly used self-reported measures that define personality traits. Then, we summarize the characteristics of the candidate genes for personality traits and investigate gene variants that have been suggested to be associated with personality traits.

기업경영에 있어서 인성기능의 휴먼웨어적 접근 (A Study on the Function of Personality as a Human-ware in Management)

  • 이철우
    • 산업경영시스템학회지
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    • 제22권51호
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    • pp.11-19
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    • 1999
  • This study intends to define $\ulcorner$personality$\lrcorner$ as $\ulcorner$Human-ware$\lrcorner$ based on $\ulcorner$Gene-ware$\lrcorner$ in business management. The sides of personality in management are important source of manifestation of ‘Synergy’, because the importance of personality, that is, $\ulcorner$attitude$\lrcorner$ in individuals is increasing compared with the traditional techniques, $\ulcorner$craft$\lrcorner$. In this work it is considered that Human-ware activates interchange in reciprocal relation between Gene-ware and Hard-ware and performs balancing, intermediating (catalyzing) functions in relative that things(Geneware $\leftrightarrow$ Humanware $\leftrightarrow$ Hardware). $\ulcorner$Gene-ware$\lrcorner$ represents factor and phenomena of life in evolutionary information as human instincts, system of Gene-duum(Gene+Residuum(in phenomenology) ), Synchronization(in structuralism). In this view, this paper defines the concepts and effects of personality in management as the results of creative and stational functions of Human-ware. And this paper intends to identify the strata of psycho in human as three vertical aspects of $\ulcorner$Manifest$\lrcorner$, $\ulcorner$Latent$\lrcorner$, and $\ulcorner$Found$\lrcorner$, in this respects, function of Human-ware have analogy to that of Manifest in psychological behaviors. Finally, reviewing the Ford system based on Fordism and Taylor's system in Industrial Engineering, pursues the meaning and importance of personality, that is Humanware in management.

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Brain-Derived Neurotrophic Factor(BNDF) Val66Met 유전자 다형성과 성격 특성에 대한 연합연구 (An Association Study of the Brain-Derived Neurotrophic Factor Genes Polymorphisms and Personality Traits)

  • 함병주;안희범;조수민;류성곤;최명진;이민수;최인근
    • 생물정신의학
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    • 제12권2호
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    • pp.216-220
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    • 2005
  • Background:Brain-derived neurotrophic factor(BDNF) genes are thought to be important factors in some personality traits. The goal of this study was to determine the role of these genes in personality traits. Method:The participants included 170 healthy adults with no history of psychiatric disorders and other physical illnesses for the last 6 months. All participants were tested by the Temperament and Character Inventory (TCI). BDNF Val64Met gene polymorphisms were analyzed with PCR(Polymerase Chain Reaction). Differences on TCI dimensions and sub-scales among groups were examined with ANOVA. Result:There was a significant correlation between BDNF Val64Met and Persistence(PS)(p=0.036) in female subjects, but none with the other TCI dimensions. A post-hoc comparison revealed significant a difference between Val/Val and Met/Met (p=0.031). Conclusion:Our study suggests that the BDNF Val64Met gene polymorphism is associated with persistence in Korean female subjects, but the small number of subjects limits generalization of our results. Further studies with a larger number of homogenous subjects are needed to confirm whether the BDNF gene is related to personality traits.

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도파민 D2 수용체 다형성과 보상의존성 성격특성과의 관련성 (Association between D2 Dopamine Receptor Gene Polymorphisms and Reward Dependence Personality Traits)

  • 강이헌;이헌정;곽강호;김린;이민수;서광윤
    • 생물정신의학
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    • 제11권1호
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    • pp.26-32
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    • 2004
  • Background:The dopaminergic genes have been implicated with some personality traits. Many recent studies indicated that there is a correlation between D2 dopamine receptor gene(DRD2) polymorphisms and the personality traits. The purpose of this study is to investigate a possible association between DRD2 gene (TaqI A, TaqI B) polymorphism and personality traits. Methods:The subjects were consisted of 173 blood-unrelated young female Koreans with a mean age(${\pm}SD$) of 13.88(${\pm}0.29$) years. These volunteers were recruited from one of the junior high schools in Seoul and were tested by the Korean version of the Temperament and Character Inventory(TCI). Genotyping of the DRD2 polymorphisms by PCR methods were carried out. Two DRD2 gene polymorphisms were classified and individually assessed as follows:TaqI A1+ vs A1-, TaqI B1+ vs B-. The associations between the TCI scores and TaqI A, TaqI B polymorphisms were assessed by Student's t-test. Results:In the 173 subjects, the allele frequencies of the DRD2 TaqI A1, TaqI B1 alleles ranged from 0.42 to 0.43, and these results are quite different from the ranges of 0.15-0.20 in the case of a Caucasian population. The genotype frequencies of DRD2(TaqI A1, TaqI B1) variants showed no significant deviation from the Hardy-Weinberg equilibrium. RD4(dependence vs. independence) of Cloninger's TCI, a sub-dimension of Reward Dependence, was significantly higher in the subjects having DRD2 less frequent alleles than those without these alleles. Conclusion:This study suggests that the female subjects carrying the less frequent DRD2 alleles exhibited higher reward-dependent personality trait compared to those without these alleles.

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5-HTTLPR과 COMT 유전자 다형성과 성격 특성에 대한 연합연구 (An Association Study of the 5-HTTLPR and COMT Genes Polymorphisms and Personality Traits)

  • 하지현;함병주;류성곤;황태연;이종국;이유상;이정식;강대엽;최인근;이민수
    • 생물정신의학
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    • 제11권2호
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    • pp.88-93
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    • 2004
  • Background:Serotonin transporter gene-linked polymorphism region(5-HTTLPR) and catechol-O-methyltransferase( COMT) genes are thought to be important factors in some personality traits and the etiology of anxiety disorder. The goal of this study was to determine the role of these genes in personality traits. Method:The participants included 116 healthy adults with no history of psychiatric disorders and other physical illness for the last 6 months. All participants were tested by Temperament and Character Inventory(TCI). The 5-HTTLPR, COMT val158met gene polymorphisms were analyzed with PCR(Polymerase Chain Reaction). Differences on TCI dimensions and sub-scales among groups were examined with t-test and ANOVA. Result:There were possible relationships of the 5-HTTLPR with self-transcendence(P=0.050) and COMT val158met polymorphism with cooperativeness(P=0.053). Conclusion:We found associations between 5-HTTLPR, COMT polymorphisms and the some TCI character dimensions. Further studies of polymorphisms of other genes and their interactions may clarify the complex relationship between personality and genes.

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한국인 알코올중독 환자의 예후인자에 관한 연구 : 심리적, 사회적, 생물학적 요인을 중심으로 (A Study for The Prognostic Indicators of Korean Alcoholics in Psychological, Social and Biological Aspects)

  • 성상경;장환일
    • 생물정신의학
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    • 제2권2호
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    • pp.218-236
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    • 1995
  • The author studied prognostic indicators of sixty Korean male alcoholics in psychological, social and biological aspects who were divided into abstinent and drinking groups. Thirty patients were assigned to each group. They were controlled in age and sex. Both groups were compared in terms of the demographic characteristics, past drinking history, treatment history, famaily history, ego strength and personality factors differences and distribution of dopamine $D_2$ receptor gene Al allele. Also the author studied relation of clinical course, alcoholic family history and dopamine $D_2$ receptor gene Al allele in both groups. The results were as follows; 1) The abstinent group had higher rate of married state, higher economic status, longer education years and maintained more stable job than the drinking group. But made no differences in occupation and religion. 2) The abstinent group showed higher rate of living with family members than the drinking group, and wives and fellows of the alcoholics anonymous were important factors for maintenance of abstinence. Family loading and parent's characters were not different. 3) The abstinent group had longer maximal length of abstinence but mean amount of alcohol consumption per day were larger than the drinking group. But there were no differences in duration of past drinking, drinking pattern, main drinking time, first drinking age and preference of the kind of alcoholic beverage in the past drinking history. 4) The abstinent group showed stronger treatment motivation, absolute abstinence in treatment goal, more voluntary adimission and maintained longer therapeutic relationship otter discharge than the drinking group. But both groups showed negative attitude toward antabuse therapy. 5) The abstinent group had higher mean score in ego strength scale than the drinking group. 6) In the personality factor questionnaire, the abstinent group showed strong laugh poise and the trait of praxernia, conservatism personality but the drinking group showed tough poise, the trait of weak ego strength(unstableness) and tough mindedness personality. 7) In comparision of dopamine $D_2$ receptor gene A1 allele, the prevalence of A1 allele was seventy percent and the frequency was 0.38 in the abstinent group. The prevalence of A1 allele was sixty percent and the frequency was 0.42 in the drinking group. Both groups were not significantly different in A1 allele prevalence and frequency. 8) In comparision of dopamine $D_2$ receptor gene A1 allele according to alcoholic family history, the prevalence of A1 allele was seventy percent and the frequency was 0.43 in the family history positive group. The prevalence of A1 allele was sixty-one percent and the frequency was 0.38 in the family history negative group. Both groups were not significantly different in A1 allele prevalence and frequency. In comparision of past drinking history according to alcoholic family history, the family history positive group showed earlier first drinking and problem drinking, but the family history negative group hod longer duration of past drinking. The mean amount of alcohol consumption per day, the longest duration of abstinence and Alcoholism Screening Test of Seoul Natoinal Mental Hospital(NAST) results were not significant. In conclusion, the results suggest that successful prognostic indicators of Korean alcoholics are married state, higher economic status, longer education years, stable job, living with family members, longer abstinence during past drinking history, strong treatment motivation, absolute abstinence in treatment goal, voluntary adimission, maintained therapeufic relationship, strong ego strength and the trait of praxernia, conservatism personality. But occupation, religion, alcoholic family history, parent's characters, duration of past drinking, drinking pattern, main drinking time, first drinking age, preference of the kind of alcoholic beverage, attitude to antabuse therapy and distribution of dopamine $D_2$ receptor A1 allele were not significantly related to the prognostic indicators of Korean alcoholics.

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아동행태 특성에 따른 유치원 내 어린이 놀이터 공간 특성 -충청북도 청주지역 내 유치원을 중심으로- (Features of Children's Playground Space in Kindergarten According to Children's Behavior -Focused on Kindergarten of Cheongju, Chungbuk-)

  • 정유진;정진주
    • 한국농촌건축학회논문집
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    • 제15권4호
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    • pp.9-16
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    • 2013
  • The purpose of this study is presented playground space for early childhood facilities. Describes whether any development of children, and how to respond in accordance with each of the activities. The infants and toddlers life cycle is a continuation of play. Toddlers to play is the essence of life itself, through play, the world embracing and digestive, raising ideas and emotions expressed through play. It is time that paves the growth of infants age children. And equipped with personality, values, emotions, attitudes, play a very important role in this process. Play it delivers, it can not learning education. Sympathetic and experience through play, and be equipped to allow the personality, social, physical. So, we have an obligation required to provide adequate facilities and play so that children can grow properly. In this paper, from the limited play space and is listed on the importance alive to give the children a sense of space to get the sympathetic. And, analysis shown about affect for children each play, and space. In this paper, we performed a study is Performed a case studies of and domestic kindergarten and foreign kindergarten where the differences between the various lists and how to derive a plan for solving the problem by comparison and analysis were performed.

국내외 홍채학 연구동향 (A Review of Iridology)

  • 임영우;박성일;박영재;박영배
    • 대한한의진단학회지
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    • 제17권1호
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    • pp.1-16
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    • 2013
  • Objectives Iridology is a field of study that diagnoses various systemic diseases through analysis of colors, structural characteristics and changes in iris. The purpose of this study was to review previously published study results of the iridology. Methods The studies were searched with the keyword "iridology" through search engines such as SCOPUS, Pub med, RISS, and NDSL. Total of 36 iridology-related studies published from 1980 to 2012 were analyzed. Results Most diagnoses of systemic disease through iris markings were insignificant. The studies on relevance of gene polymorphism and iris constitution were highly significant. The studies on relevance of Sasang constitution and iris constitution varied in results depending on diagnosis methods. The studies on relevance of iris constitution and diseases had significant results. The structural characteristics of iris were related to certain personality. Conclusions The studies on utility of iris diagnosis and diagnostic markings were negative, but the relevance of constitution, heredity, and iris diagnosis was positive. A persistent in-depth study on relevance of iris and constitution is needed in the future.

특수 목적견으로서의 품성 및 능력 관련 유전자들에 관한 생물정보학적 분석 (Bioinformatic Analysis of the Canine Genes Related to Phenotypes for the Working Dogs)

  • 권윤정;어정우;최봉환;최유리;김정안;김다희;김태헌;성환후;김희수
    • 생명과학회지
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    • 제23권11호
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    • pp.1325-1335
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    • 2013
  • 특수 목적견(구조견, 군견, 안내견 및 탐지견)은 집중력, 소유욕, 대담성 등을 기반으로 한 훈련시험을 통해 선별된다. 최근 특수견으로서의 특수한 능력 및 품성에 대해 유전적인 정보가 중요한 인자로 다뤄지고 있다. 본 연구에서는 특수견으로서의 개의 특수한 능력 및 품성과 관련된 유전자들의 분자적인 특징을 고찰하고자 하였다. 이전 연구에서 보고된 24개의 유전자(AR, BDNF, DAT, DBH, DGCR2, DRD4, MAOA, MAOB, SLC6A4, TH, TPH2, IFT88, KCNA3, TBR2, TRKB, ACE, GNB1, MSTN, PLCL1, SLC25A22, WFIKKN2, APOE, GRIN2B, PIK3CG)를 선택하여 품성, 후각, 운동 및 학습능력 관련 유전자, 네 가지 카테고리로 분류하였다. 본 연구에서는 생물학적인 기법을 이용하여 이 유전자들의 염색체상의 위치, 유전자들 간의 네트워크를 통한 상호관계를 조사하였으며, 어떤 생물학적 기능과 관련이 있는지 Gene Ontology 분석과 데이터베이스를 기반으로 in silico 발현 양상을 살펴보았다. 또한 이전 연구를 통하여 품성 관련 유전자들의 다양한 유전적 다형성에 대한 보고를 조사하였다. 본 연구는 특수 견으로서 주요하게 고려되는 개의 고유한 능력 및 품성 관련된 유전자에 대해 분자적 특징을 제시하고 있다. 이 후보 유전자들은 개의 특수한 표현형과의 관계를 밝힐 수 있는 연구의 기초자료로서 이용될 수 있을 뿐만 아니라 핵심적인 유전인자로 응용되어 신속하고 정확한 특수견 선발에 기여할 수 있을 것으로 전망된다.

과학기술과 관련된 사회적 쟁점에 대한 논증 프로그램이 예비 생물교사들의 의사결정 유형과 의사소통 능력에 미치는 영향 (The effects of SSI Argumentation Program on the Preservice Biology Teachers' Decision-Making Types and Communication Ability)

  • 김선영
    • 과학교육연구지
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    • 제42권1호
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    • pp.12-26
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    • 2018
  • 본 연구에서는 과학기술과 관련된 사회적 쟁점에 대한 논증 프로그램을 통해 예비 생물교사들의 의사결정 유형과 의사소통 능력의 변화를 살펴보았다. 또한 의사결정 유형과 의사소통 능력의 상관관계를 조사하고, 예비생물 교사들은 SSI 논증 프로그램 후 의사소통 및 의사결정에 관해 어떠한 경험을 하였는지 살펴보았다. SSI 논증 프로그램은 사회적 의사결정과 문제해결전략을 활용하여 개발되었으며, 낙태, 안락사, 유전자 조작 및 인공지능을 주제로 총 12차시에 걸쳐 진행되었다. 예비교사들은 SSI 문제를 파악하고, 해결책을 생각하며, 최선의 방안을 결정하도록 하였으며, 이 과정에서 소집단 토론을 통해 사회과학적 문제에 대한 논증 활동의 기회를 가졌다. 연구 결과, 예비 교사들의 의사소통 능력은 통계적으로 유의미한 향상을 나타냈으나, 의사결정 유형에는 변화가 없었다. 또한 Pearson 상관 분석 결과, 의사결정 유형 중 '합리적 유형'은 의사소통 능력과 유의미한 상관관계를 나타냈다. 예비교사들은 사회과학적 쟁점에 대한 논증 프로그램을 통해 근거, 자료, 맥락, 반론 등을 고려하여 자신의 주장을 말하는 능력이 향상되었다고 언급하였다. 또한 사회과학적 문제에 관심을 가지게 되고 다른 사람의 비판을 수용할 수 있게 되었을 뿐만 아니라 자신도 다른 사람을 배려하면서 자신의 의견을 말할 수 있게 되었다고 하여 과학교육에서 SSI 논증 활동을 통한 인성 교육의 가능성을 시사한다.