• 제목/요약/키워드: peripheral polyneuropathy

검색결과 56건 처리시간 0.02초

당뇨병성 다발신경병증의 조기 진단에서 신경전도검사의 유용성에 관한 논란: 긍정적인 관점에서 (Controversies on the Usefulness of Nerve Conduction Study in the Early Diagnosis of Diabetic Polyneuropathy: Pros)

  • 권오현
    • Annals of Clinical Neurophysiology
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    • 제10권1호
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    • pp.29-32
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    • 2008
  • Although various criteria on the diagnosis of diabetic neuropathy are applied from trial to trial, being tailored in concert with its purpose, the utmost evidences of the diagnosis are subjective symptoms and objective signs of neurologic deficit. The application and interpretation of auxiliary electrophysiological test including nerve conduction study (NCS) should be made on the context of clinical pictures. The evaluation of the functions of small, thinly myelinated or unmyelinated nerve fibers has been increasingly stressed recently with the advent of newer techniques, e.g., measurement of intraepidermal fiber density, quantitative sensory testing, and autonomic function test. And the studies with those techniques have shed light to the nature of the evolution of diabetic neuropathy. The practical application of these techniques to the diagnosis of diabetic neuropathy in the individual patients, however, should be made cautiously due to several shortcomings: limited accessibility, wide overlapping zone between norm and abnormality with resultant unsatisfactory sensitivity and specificity, difficulty in performing subsequent tests, unproven quantitative correlation with clinical deficit, and invasiveness of some technique. NCS, as an extension of clinical examination, is still the most reliable electrophysiological test in evaluating neuropathy and gives the invaluable information about the nature of neuropathy, whereas the newer techniques need more refinement of the procedure and interpretation, and the accumulation of large scaled data of application to be considered as established diagnostic tools of peripheral neuropathy.

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Guillain-Barre syndrome으로 추정되는 계증 치험 1례(例) (A case of the patient with Wei symptom suspected Guillain-Barre syndrome)

  • 정병무;신원용;최은영;윤철호;정지천;현민경
    • 대한한방내과학회지
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    • 제25권4호
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    • pp.450-456
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    • 2004
  • Guillain-Barre syndrome, or acute inflammatory polyneuritis, is a disorder in which the body's immune system attacks parts of the peripheral nervous system. The causes and mechanisms of this syndrome are unknown. Typically, Guillain-Barre syndrome can be diagnosed from the patient's symptoms and physical examination such as the rapid onset of weakness, paralysis and loss of reflexes. The analysis of CSF and electrical tests on nerve and muscle function can be performed to confirm the diagnosis. Most cases occur shortly after a viral infection. This is a clinical report about one patient suspected as having Guillain-Barre syndrome. The patient, a 62-year-old man had weakness in both legs after gastroduodenal disease. His weakness and general condition improved after Korean medical treatments, so this is reported as a potential treatment.

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糖尿病性 神經病症 1例에 대한 臨床的 考察 (A case of Diabetic Neuropathy Treatment)

  • 박지현;황희정;김종대;강석봉
    • 대한한의학방제학회지
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    • 제9권1호
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    • pp.386-386
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    • 2001
  • 경산대학교 부속 대구한방병원에 당뇨병성 신경병증으로 인한 兩下肢 冷痺症, 無力感을 주소로 내원한 환자 1例에 대하여 2000년 7월 3일부터 2000년 7월 16일까지 漢藥治療 및 鍼灸治療 등을 시행하여 下肢의 증상 및 당뇨병으로 인한 전신증상의 호전에 도움이 되었으므로 치료내용과 경과를 문헌고찰과 함께 보고하는 바이다.

당뇨병성(糖尿病性) 신경병증(神經病症) 1례(例)에 대한 임상적(臨床的) 고찰(考察) (A case of Diabetic Neuropathy Treatment)

  • 박지현;황희정;김종대;강석봉
    • 대한한의학방제학회지
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    • 제9권1호
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    • pp.387-395
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    • 2001
  • 경산대학교 부속 대구한방병원에 당뇨병성 신경병증으로 인한 양하지(兩下肢) 냉비증(冷痺症), 무력감(無力感)을 주소로 내원한 환자 1례(例)에 대하여 2000년 7월 3일부터 2000년 7월 16일까지 한약치료(漢藥治療) 및 침구치료(鍼灸治療) 등을 시행하여 하지(下肢)의 증상 및 당뇨병으로 인한 전신증상의 호전에 도움이 되었으므로 치료내용과 경과를 문헌고찰과 함께 보고하는 바이다.

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마목(麻木)과 이상감각(異常感覺)과의 연관성에 관한 연구(1) (The Study on Clinical relations of Mamok and Abnormal sensations)

  • 고성규
    • 대한한의학회지
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    • 제18권1호
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    • pp.251-266
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    • 1997
  • The results are as follows. 1. Oriental medical terms which express abnormal sensations are Bulin, Mamok, Mamokbulin. 2. Bulin, Oriental medical terminology, was used from Naegyeong's era to the Song Dynasty era and expressed as one of the symptoms in Jungpung(Stroke), Bi syndrome(Obstruction syndrom of Gi and Hyeol), Wi syndrome(Flaccid paralysis of the limbs), Hyeolbi(One of the Bi syndroms). But since the Keum Dynasty era, Mamok or Mamokbulin were more used than Bulin and that was refered as seperated disease. 3. Ma is paresthesia or dysthesia on the skin and the limbs, and the symtoms are not itchy, patients are felt like insect's crawling or bite. Mok is a stubborn symptom , the patients are felt like tree, which don't know pain and itching sensation. And therefore Ma is similar to positive phenomena and Mok is similar to negative phenomena in clinical aspect. 4. Mamok is GiHyeol(Gi is functional activities, Hyeol is blood) and Gyeonglak(Meridian system)'s disease. It's main causes are Giheo(Deficiency of Gi) and Hyeolhel(dificiency of Blood) and inducing tactors are Pung-Han-Seub(pathogenic wind-cold-dump) and Damtak(Phlegm-turbity), Eohyeol(Stagnated blood). 5. Mamok is induced from mononeuritis, multiple mononeuritis, polyneuropathy in the peripheral nervous lesions and also induced from cervical spondylosis, spinal tumour, multiple sclerosis, cerebrospinal vascular disease in central nervous systems.

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신경전도검사의 이상소견을 보이는 근긴장디스트로피 환자에서 진단된 1형 샤르코-마리-투스 병: 증례보고 (Charcot-Marie-Tooth Disease Type 1A Diagnosed Based on Abnormalities in a Nerve Conduction Study in a Patient with Myotonic Dystrophy Type 1: A Case Report)

  • 이형남;원유희
    • 대한근전도전기진단의학회지
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    • 제20권2호
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    • pp.148-152
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    • 2018
  • Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystem disorder and one of the most common muscular dystrophies affecting adults. Charcot-Marie-Tooth (CMT) disease, a common hereditary neuropathy, is characterized by atrophy of the distal limbs and peripheral nerve abnormalities. The authors report a rare case involving a 24-year-old female who was diagnosed simultaneously with both DM1 and CMT1A based on the results of a nerve conduction study (NCS). The patient, who had previously been diagnosed with DM1, was admitted for lower extremity pain. Her electrodiagnostic examination continued to reveal severe sensorimotor demyelinating polyneuropathy, and a genetic study was performed to confirm whether she had other hereditary neuropathies, except DM1, that suggested CMT1A, the most common phenotype of CMT. Severe abnormalities in an NCS in a DM1 patient may suggest the incidental coexistence of hereditary neuropathies, and further evaluations, such as genetic studies, should be performed for proper diagnosis.

장천공이 동반된 Churg-Strauss 증후군 1예 (A Case of Churg-Strauss Syndrome with Interstinal Perforation)

  • 박정훈;정윤석;김양기;이영목;황정화;김기업;김동원;어수택;김재준
    • Tuberculosis and Respiratory Diseases
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    • 제66권5호
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    • pp.374-379
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    • 2009
  • 천식조절 중이던 환자에서 임상증상과 조직검사를 바탕으로 진단된 Churg-Strauss 증후군을 진단하고 치료 중 발생한 장천공을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

광용적맥파와 정량적 감각검사의 비교를 통한 진단적 유용성 (Diagnostic Usefulness of Quantitative Sensory Test Comparison with Photoplethysmography)

  • 이상봉;서정혁
    • 한국방사선학회논문지
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    • 제9권5호
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    • pp.315-322
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    • 2015
  • 본 논문의 목적은 당뇨병 및 신경병증의 병력이 없는 17명의 일반 성인을 대상으로 한 정량적 감각검사(QST)와 광용적맥파(PPG)와의 비교를 통해 정량적 감각검사의 임상적 유용성을 파악하는 것이며, 광용적맥파 검사를 이용한 혈당수치에 따른 자율신경계의 부교감신경의 변화를 살펴보는 것이다. 일반인을 대상으로 혈당검사와 광용적맥파 검사를 실시하여 상관관계를 분석한 결과 혈당수치에 따라 자율신경계 부교감신경이 느려지는 상관관계를 보였다. 이상의 결과에서 정량적 감각 검사가 주관적 평가에 의한 검사이기는 하나 검사의 민감도를 신뢰할 수 있다고 보이며 따라서 말초 신경의 평가도구로서 정량적 감각검사가 당뇨병성 신경병증 등의 진단의 민감도를 높이는데 폭넓게 이용될 수 있을 것으로 보이며, 광용적맥파 검사가 심박변화율에 의한 자율신경계를 평가하는 후속연구에 기초자료연구로 이용될 수 있을 것으로 사료된다.

급성 자율 감각 신경병증 1례 (A case of Acute Autonomic and Sensory Neuropathy)

  • 이종문;권도영;고성범;김병조;박민규;박건우;이대희
    • Annals of Clinical Neurophysiology
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    • 제4권1호
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    • pp.70-73
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    • 2002
  • Acute autonomic neuropathy is a rare disease. Since the first case was reported by Young et.al., in 1969, a number of similar cases have been described, with some variation of the accompanied neurologic deficits. Acute autonomic and sensory neuropathy(AASN) is characterized by the acute onset of autonomic dysfunction and sensory disturbances. A 16-year-old girl experienced high fever($40^{\circ}C$) and erythematous rash on whole trunk and face followed by pain and sensory loss over the whole body, dysphagia, ataxia, urinary retention, and postural hypotension. There was no evidence of limb weakness. The electrophysiologic studies of this patient revealed sensory polyneuropathy and the various autonomic function test showed autonomic dysfunction. The recovery of her autonomic and sensory symptoms is incomplete, three months after the onset of the symptoms. The etiology of the acute autonomic and sensory neuropathy is not known. Most previous authors have suggested the dysautonomia may be an acute immunological damage to peripheral fibers of the autonomic nervous system. We report a case of acute autonomic and sensory neuropathy.

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Concurrency of Guillain-Barre syndrome and acute transverse myelitis: a case report and review of literature

  • Tolunay, Orkun;Celik, Tamer;Celik, Umit;Komur, Mustafa;Tanyeli, Zeynep;Sonmezler, Abdurrahman
    • Clinical and Experimental Pediatrics
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    • 제59권sup1호
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    • pp.161-164
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    • 2016
  • Guillain-$Barr{\acute{e}}$ syndrome and acute transverse myelitis manifest as demyelinating diseases of the peripheral and central nervous system. Concurrency of these two disorders is rarely documented in literature. A 4-year-old girl presenting with cough, fever, and an impaired walking ability was admitted to hospital. She had no previous complaints in her medical history. A physical examination revealed lack of muscle strength of the lower extremities and deep tendon reflexes. MRI could not be carried out due to technical problems; therefore, both Guillain-$Barr{\acute{e}}$ syndrome and acute transverse myelitis were considered for the diagnosis. Intravenous immunoglobulin treatment was started as first line therapy. Because this treatment did not relieve the patient's symptoms, spinal MRI was carried out on the fourth day of admission and demyelinating areas were identified. Based on the new findings, the patient was diagnosed with acute transverse myelitis, and high dose intravenous methylprednisolone therapy was started. Electromyography findings were consistent with acute polyneuropathy affecting both motor and sensory fibers. Therefore, the patient was diagnosed with concurrency of Guillain-$Barr{\acute{e}}$ syndrome and acute transverse myelitis. Interestingly, while concurrency of these 2 disorders is rare, this association has been demonstrated in various recent publications. Progress in diagnostic tests (magnetic resonance imaging and electrophysiological examination studies) has enabled clinicians to establish the right diagnosis. The possibility of concurrent Guillain-$Barr{\acute{e}}$ syndrome and acute transverse myelitis should be considered if recovery takes longer than anticipated.