Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Churg-Strauss Syndrome with Interstinal Perforation

장천공이 동반된 Churg-Strauss 증후군 1예

  • Park, Jung Hoon (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Jung, Yun Seok (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Kim, Yang Ki (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Lee, Young Mok (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Hwang, Jung Hwa (Department of Radiology, School of Medicine, Soonchunhyang University) ;
  • Kim, Ki-Up (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Kim, Dong Won (Department of Pathology, School of Medicine, Soonchunhyang University) ;
  • Uh, Soo-Taek (Department of Internal Medicine, School of Medicine, Soonchunhyang University) ;
  • Kim, Jae Jun (Department of Surgery, School of Medicine, Soonchunhyang University)
  • 박정훈 (순천향대학교 의과대학 내과학교실) ;
  • 정윤석 (순천향대학교 의과대학 내과학교실) ;
  • 김양기 (순천향대학교 의과대학 내과학교실) ;
  • 이영목 (순천향대학교 의과대학 내과학교실) ;
  • 황정화 (순천향대학교 의과대학 영상의학교실) ;
  • 김기업 (순천향대학교 의과대학 내과학교실) ;
  • 김동원 (순천향대학교 의과대학 병리학교실) ;
  • 어수택 (순천향대학교 의과대학 내과학교실) ;
  • 김재준 (순천향대학교 의과대학 외과학교실)
  • Received : 2009.03.11
  • Accepted : 2009.05.07
  • Published : 2009.05.30
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Abstract

Churg-Strauss syndrome (CSS) or allergic granulomatous angiitis is a rare syndrome that is characterized by hypereosinophilic systemic necrotizing vasculitis affecting small- to medium-sized arteries and veins. In general, it occurs in individuals with pre-existing allergic asthma. When CSS appears in patients, it has the following characteristics: eosinophilia of more than 10% in peripheral blood, paranasal sinusitis, pulmonary infiltrates, histological proof of vasculitis with extravascular eosinophils, and mononeuritis multiplex or polyneuropathy. Therapeutic trials dedicated to Churg-Strauss syndrome have been limited due to the rarity of this disorder and the difficulty in making a histological diagnosis. Proper treatment of patients with CSS is not widely known. In this case study, we report on our experience with an unusual patient case, characterized by purpura and a perforation of the small intestine after inadequate steroid therapy.

천식조절 중이던 환자에서 임상증상과 조직검사를 바탕으로 진단된 Churg-Strauss 증후군을 진단하고 치료 중 발생한 장천공을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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