• 대한간호학회지
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• 제45권5호
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• pp.661-670
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• 2015

Purpose: The purpose of this study was to examine the mediation of psychological distress in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life in order to provide a basis for planning nursing interventions to improve the quality of life in cancer patients. Methods: A purposive sample of 130 patients treated with chemotherapy were recruited in the cross-sectional survey design. Data were collected using self-report questionnaires. The instruments were the Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT), Hospital Anxiety Depression Scale (HADS), and Functional Assessment of Cancer Therapy-General (FACT-G). Results: The mean score for disturbance in ADL from chemotherapy induced peripheral neuropathy was 3.30. Overall quality of life was 2.48. The mean score was 1.04 for psychological distress. The prevalence was 35.4% for anxiety and 47.7% for depression. There were significant correlations among the three variables, disturbance in ADL from chemotherapy induced peripheral neuropathy, psychosocial distress, and quality of life. Psychosocial distress had a complete mediating effect (${\beta}$= -.74, p <.001) in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life (Sobel test: Z= -6.11, p <.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on disturbance of ADL management, and decrease of psychological distress are highly recommended to improve quality of life in cancer patients.

• 혜화의학회지
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• 제13권1호
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• pp.47-59
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• 2004

Objectives & Methods: We investigated 28 books to study etiology and pathology of Son-Bal Jeorim. Result and Conclusion 1. The eiology of Son-Bal Jeorim is same as it of Bee Jeung(痺症). 2. Generally speaking, the cause of Bee Jeung was distributed Wind(風), Coldness(寒), Wetness (濕) of meridian. Bee Jeung can be devided into SilBi(實痺) and HeoBi(虛痺). In SilBi(實痺) there are PungHanSeupBi(風寒濕痺) and YeolBi(熱痺). In HeoBi(虛痺), there are GiHyeolHeoBi(氣血虛痺), EumheoBi(陰虛痺) and YangHeoBi(陽虛痺). 3. Son-Bal Jeorim belong to peripheral neuropathy in western medicine. 4. Syndrome of acute motor paralysis with variable disturbance of sensory and autonomic function, subacute sensorymotor paralysis, syndrome of chronic sensorimotor polyneuropathy, neuropathy with mitochondrial disease, syndrome of mononeuropathy or nerve plexusopathy. 5. Peripheral neuropathy is caused by carpal tunnel syndrome, diabetic neuropathy, uremic neuropathy, hepatic neuropathy, hypothyroid neuropathy, hyperthyroid neuropathy, neuropathy due to malnutrition, neuropathy due to toxic material, neuropathy due to drug, paraneoplastic neuropathy, hereditary neuropathy, etc. 6. Cerebral apoplexy, myelopathy, peripheral circulatory disturbance, anxiety syndrome cause symptoms of peripheral neuropathy

• 대한암한의학회지
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• 제24권2호
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• pp.23-31
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• 2019

Objective : Peripheral neuropathy refers to the symptoms caused by damage to peripheral fibers, inflammation and degeneration. This study reports the effects of moxibustion, electric moxibustion, and pharmacopuncture including GeonChil(Rhus verniciflua stokes, 乾漆)and Whalhyul(活血) pharmacopuncture on patients with peripheral neuropathy induced by anti-cancer drugs and chemotherapy. Method : We administered moxibustion, electric moxibustion, GeonChil and Whalhyul pharmacopuncture to two patients who showed peripheral neuropathy induced by anti-cancer drugs and chemotherapy. The symtoms were evaluated using Visual Analog Scale (VAS) and chemotherapy induced peripheral neuropathy assessment tool (CIPNAT). Results : Following observations were made after treatments. Case 1 : After nine procedures, the score of VAS was decreased. Feeling of cold and numbness were improved, and as rotation movement of ankle was also possible, gait disturbance were improved. Case 2 : After, seven procedures symptoms of both shoulder pain were improved, and the symptoms of peripheral neuropathy were eliminated. Conclusion : We found the possibility of symptom improvement after moxibustion, electric moxibustion, and pharmacopuncture treatment on peripheral neuropathy caused by anti-cancer drugs. Clinical studies of pilot study and control settings will need to be carried out later.

• 대한한방내과학회지
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• 제31권2호
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• pp.372-379
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• 2010

Objective : The purpose of this study was to report the effect of Bogijetong-tang on diabetic peripheral neuropathy. Methods : Nine patients who were diagnosed or suspected with diabetic peripheral neuropathy enrolled in this study. They took Bogijetong-tang 2 or 3 times a day and were given acupuncture therapy. To evaluate the therapeutic effect, Visual Analog Scale (VAS) or Total Symptom Score (TSS) were examined at intervals of about 7 days. Result : TSS score decreased an average of 2.74 points and VAS scores decreased an average of 3.67 points. As the pain decreased, accompanied gait disturbance also improved in some patients. Conclusion : Bogijetong-tang is effective in treating diabetic peripheral neuropathy, but study of the concrete mechanism and efficacy is needed.

• 한방안이비인후피부과학회지
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• 제35권3호
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• pp.123-132
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• 2022

Objectives : The purpose of this study is to report a case of erythematotelangiectatic type rosacea and peripheral facial palsy improved by Korean medicine treatment with Soshioho-tang gagambang. Methods : The patient visited our clinic due to facial flushing and peripheral facial palsy symptoms. Based on Sanghallon provision, we treated this case with Soshiho-tang gagambang. The result of treatment was evaluated by Visual Analogue Scale(VAS), Dermatology Life Quality Index(DLQI) and House-Brackmann Grading System(HBGS). Results : After 12 days of taking Soshiho-tang gagambang, VAS of rosacea was decreased from 9 to 4 and DLQI was decreased from 22 to 5. After treatment, rosacea with facial flushing was improved and HBGS was reduced from 3 to 1. Conclusions : This study shows the possibility of taking Soshiho-tang gagambang for erythematotelangiectatic type rosacea and peripheral facial palsy derived from stress, fatigue and sleep disturbance according to Sanghallon provision.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.99-102
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• 1996

The ultimate object of FES is on the recovering function of body and shape demaged from desease or injury to original state. On this study, object is recovering of gait function of the disabled who, especially, have gait disturbance. Paralyzed muscle from the central nerve disable, if peripheral nerves which be in the lower part of the harmed are activated, muscle contraction is possible. The traumatic trouble, peripheral nerves aren't connected to a central nerve but origin of peripheral nerve cells which are in the lower part of the harmed are alive, react on stimulation. We design 4-channel stimulator, being based on standard stimuli pattern. stimulator is manufactured with compact size and light weight to portable.

• Annals of Clinical Neurophysiology
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• 제23권2호
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• pp.130-133
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• 2021

X-linked Charcot Marie Tooth disease type 1 (CMTX1) is a clinically heterogenous X-linked hereditary neuropathy caused by mutation of the gene encoding gap junction beta 1 protein (GJB1). Typical clinical manifestations of CMTX1 are progressive weakness or sensory disturbance due to peripheral neuropathy. However, there have been some CMTX1 cases with accompanying central nervous system (CNS) manifestations. We report the case of a genetically confirmed CMTX1 patient who presented recurrent transient CNS symptoms without any symptom or sign of peripheral nervous system involvement.

• 한국정보통신학회논문지
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• 제14권5호
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• pp.1209-1216
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• 2010

당뇨 합병증 등으로 인한 말초혈류 및 신경장애, 수족냉증 및 손가락 관절염, 통증 질환이 증가하고 있으며, 이러한 문제를 개선할 수 있는 손가락 질환 전용 치료기기가 전무한 상태로 이와 관련된 치료기의 개발이 필요하다. 본 연구에서는 시변 미약자기장을 이용하여 비침습적으로 말초혈류/신경개선과 손가락 류마티스 치료를 위한 솔레노이드 원통형 코일을 제작하고, 다양한 치료목적에 사용하기 위해서 3가지 자극모드(N, S, N/S)와 자극주파수(0.25, 0.5, 1hz)를 선택할 수 있는 시스템을 설계하였다. 자속밀도 측정 프로브를 솔레노이드의 중심에서부터 거리를 0 ~ 3cm 단계로 자극방식과 주파수별로 자속밀도를 측정하였다. 자속밀도를 측정한 결과, 모든 자극방식과 주파수에서 솔레노이드 내부의 중심(0cm)에 근접할수록 자속밀도가 급격히 증가하였다. 솔레노이드 중심 자속밀도는 N자극 (294.3mT)과 S자극(293.8mT)에서는 1Hz, N/S자극(275.4mT)에서는 0.25Hz에서 가장 높게 측정되었다. 본 논문에서는 다양한 패턴과 강도의 자기장을 이용하여 다양한 손가락 질환을 치료할 수 있는 솔레노이드형 치료기기를 개발하였다. 솔레노이드 내부 자속밀도를 측정함으로써 손가락 말초질환 개선을 위한 미약자기장 시스템의 임상 적용 가능성을 확인하였다.

• Journal of Ginseng Research
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• 제35권4호
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• pp.442-448
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• 2011

We previously reported that in vitro anti-platelet activity of tissue-cultured mountain ginseng (TCMG) ethanol extracts show improved efficacy when compared with commercial ginseng products such as Korean red ginseng and Panax ginseng. However, information on the anti-platelet activity of the ethyl acetate fraction from TCMG adventitious roots is limited. Therefore, in this study, we further investigated the effects of an ethyl acetate extract of TCMG (EA-TCMG) adventitious roots on in vitro antiplatelet activity in whole human blood and its effect on peripheral blood flow in mice. We found that EA-TCMG inhibited platelet aggregation with $IC_{50}$ values of 271, 180, and 147 ${\mu}g$/mL induced by collagen, adenosine-5'-diphosphate, and arachidonic acid, respectively. Among the three agonists used, thromboxane $A_2$ formation induced by arachidonic acid was markedly suppressed. Furthermore, EA-TCMG improved the peripheral circulatory disturbance by improving vascular blood flow. In conclusion, these results suggest that ethyl acetate extracts from TCMG adventitious roots might inhibit vascular platelet aggregation and thrombus formation.

• Journal of Chest Surgery
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• 제49권5호
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• pp.408-412
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• 2016

A 50-year-old female patient with visual disturbances was referred for further evaluation of a heart murmur. Fundoscopy revealed a Roth spot in both eyes. A physical examination showed peripheral signs of infective endocarditis, including Osler nodes, Janeway lesions, and splinter hemorrhages. Our preoperative diagnosis was subacute bacterial endocarditis with severe aortic regurgitation. The patient underwent aortic valve replacement and was treated with intravenous antibiotics for 6 weeks postoperatively. The patient made a remarkable recovery and was discharged without complications. We report this case of subacute endocarditis with all 4 classic peripheral signs in a patient who presented with visual disturbance.