Journal of Korean Traditional Oncology (대한암한의학회지)

Korean Association of Traditional Oncology (대한암한의학회)
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Case reports: Effect of Korean Medicine Including Pharmacopuncture on Chemotherapy Induced Peripheral Neuropathy

항암제 유발 말초신경병증 한의 치험 2례

  • Hong, Sang Hoon (Department of Internal Medicine, College of Korean Medicine, Dong-Eui University) ;
  • Jung, Yu-jin (Department of Internal Medicine, College of Korean Medicine, Dong-Eui University)
  • 홍상훈 (동의대학교 부속 한방병원 내과) ;
  • 정유진 (동의대학교 부속 한방병원 내과)
  • Received : 2019.11.29
  • Accepted : 2019.12.20
  • Published : 2019.12.30
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Abstract

Objective : Peripheral neuropathy refers to the symptoms caused by damage to peripheral fibers, inflammation and degeneration. This study reports the effects of moxibustion, electric moxibustion, and pharmacopuncture including GeonChil(Rhus verniciflua stokes, 乾漆)and Whalhyul(活血) pharmacopuncture on patients with peripheral neuropathy induced by anti-cancer drugs and chemotherapy. Method : We administered moxibustion, electric moxibustion, GeonChil and Whalhyul pharmacopuncture to two patients who showed peripheral neuropathy induced by anti-cancer drugs and chemotherapy. The symtoms were evaluated using Visual Analog Scale (VAS) and chemotherapy induced peripheral neuropathy assessment tool (CIPNAT). Results : Following observations were made after treatments. Case 1 : After nine procedures, the score of VAS was decreased. Feeling of cold and numbness were improved, and as rotation movement of ankle was also possible, gait disturbance were improved. Case 2 : After, seven procedures symptoms of both shoulder pain were improved, and the symptoms of peripheral neuropathy were eliminated. Conclusion : We found the possibility of symptom improvement after moxibustion, electric moxibustion, and pharmacopuncture treatment on peripheral neuropathy caused by anti-cancer drugs. Clinical studies of pilot study and control settings will need to be carried out later.

Keywords

References

  1. Kim J E. The family support and the management of side effects from chemotherapy for female cancer patient [master'thesis] 2009. Ewha womans university:
  2. Windebank, Anthony J, Grisold, Wolfgang. Chemotherapy-induced neuropathy. J. of the Peripheral Nervous System 13(1):27-46, 2008. https://doi.org/10.1111/j.1529-8027.2008.00156.x
  3. Argyriou AA, Bruna J, Marmiroli P, Cavaletti G. Chemotherapy induced peripheral neurotoxicity (CIPN): An update. Crit Rev Oncol Hematol 82(1):51-77, 2012. https://doi.org/10.1016/j.critrevonc.2011.04.012
  4. Yang GS, Choe MA. Effect of anorexia and neuropathic pain induced by cisplatin on hindlimb muscles of rat. J Korean Acad Nurs 43(3):361-369, 2013. https://doi.org/10.4040/jkan.2013.43.3.361
  5. Gedge D, Rosson GD. Chemotherapy-induced neuropathy. Clin Podiatr Med Surg 23(3):637-649, 2006. https://doi.org/10.1016/j.cpm.2006.04.009
  6. Visovsky C. Characterization of chemotherapy-induced peripheral neuropathy [master'thesis] 2002. Western Reserve University, Ohio:
  7. Oh PJ, Kim YL. Effectiveness of non-pharmacologic interventions in chemotherapy induced peripheral neuropathy - A systematic review and meta-analysis. J Korean Acad Nurs 48(2):123-142, 2018. https://doi.org/10.4040/jkan.2018.48.2.123
  8. Ogawa K, Ogawa M, Nishijima K, Tsuda M, Nishimura G. Efficacy of contact needle therapy for chemotherapy-induced peripheral neuropathy. Evid Based Complement Alternat Med 2013:1-5, 2013.
  9. Ma S, Cornford ME, Vahabnezhad I, Wei S, Li X. Responses of nitric oxide synthase expression in the gracile nucleus to sciatic nerve injury in young and aged rats. Brain Res 855(1):124-131, 2000. https://doi.org/10.1016/S0006-8993(99)02379-3
  10. Litscher G, Wang L, Huber E, Nilsson G. Changed skin blood perfusion in the fingertip following acupuncture needle introduction as evaluated by laser doppler perfusion imaging. Lasers Med Sci 17(1):19-25, 2002. https://doi.org/10.1007/s10103-002-8262-9
  11. Trivedi MS, Hershman DL, Crew KD. Management of chemotherapy-induced peripheral neuropathy. Am J Hematol Oncol 11:6, 2015.
  12. Brami C, Bao T, Deng G. Natural products and complementary therapies for chemotherapy-induced peripheral neuropathy: A systematic review. Crit Rev Oncol Hematol 98:325-334, 2016. https://doi.org/10.1016/j.critrevonc.2015.11.014
  13. Kwak MK, Kim EJ, Lee ER, Kwon IG, Hwang MS. Characteristics and quality of life in patients with chemotherapy-induced peripheral neuropathy. J Korean Onclo Nurs 10(2):231-239, 2010. https://doi.org/10.5388/jkon.2010.10.2.231
  14. Thomas JK, Lisa MD. Therapy of chemotherapy-induced peripheral neuropathy. Br J Haematol 145:3-14, 2009. https://doi.org/10.1111/j.1365-2141.2008.07558.x
  15. Jeong YJ, Kwak MA, Seo JC, Park SH, Bong JG, Shin IM, Park SH. Acupuncture for the treatment of taxane-induced peripheral neuropathy in breast cancer patients: A pilot trial. Evid Based Complement Alternat Med 2018:1-11, 2018.
  16. Han CW, Hwang EH, Kim HJ, Shin HJ. Acupuncture for chemotherapy-induced peripheral neuropathy: a pilot study. Korean J. Oriental Physiology & Pathology 28(4):460-463, 2014.
  17. Kim SY, Choi JY, Yun YJ, Park SH, Han CW. A Case Report of long-term acupuncture treatment in bortezomib induced peripheral neuropathy. Korean Journal of Acupuncture 32(4):208-212, 2015. https://doi.org/10.14406/acu.2015.024
  18. Zhaoxue Lu, Benjamin L, Tracy Hammerstrom. Treatment of chemotherapy-induced peripheral neuropathy in integrative oncology: A survey of acupuncture and oriental medicine practitioners. THE J. of Alternative and Complementary Medicine 23(12):964-970, 2017. https://doi.org/10.1089/acm.2017.0052
  19. Yoon JW, Jeon JH, Lee YW, Cho CK, Kwon KR, Shin JE, Stephen Sagar, Raimond Wong, Yoo HS. Sweet bee venom pharmacopuncture for chemotherapy-induced peripheral neuropathy. J Acupunct Meridian Stud 5(4):156-165, 2012. https://doi.org/10.1016/j.jams.2012.05.003
  20. Park JW, Jeon JH, Yoon JW, Jung TY, Kwon KR, Cho CK, Lee YW, Stephen Sugar, Raimond Wong, Yoo HS. Effects of sweet bee venom pharmacopuncture treatment for chemotherapy-induced peripheral neuropathy: A case series. Integr Cancer Ther 11(2):166-171, 2012. https://doi.org/10.1177/1534735411413265
  21. 郭長青, 劉乃剛, 胡派. 針灸穴位圖解. 北京, 人民衛生出版社p.75, 92, 233, 292. 2013.
  22. Lu X, Li MM, Zhang ZL. Analysis of neiguan in great compendium of acupuncture and moxibustion. Jilin J of Chinese Medicine 38(2):236-239, 2018.
  23. Tofthagen CS, McMillan SC, Kip KE. Development and psychometric evaluation of the chemotherapy-induced peripheral neuropathy assessment tool. Cancer Nurs 34(4):E10-20, 2011. https://doi.org/10.1097/NCC.0b013e31820251de
  24. Kim JH, Lee KM, Jeon, MJ, Seol ME, Lee SH, Park JY. Symptom and interference of activities of daily living of chemotherapy-induced peripheral neuropathy in patients receiving taxanes and platinums. Asian Oncol Nurs 13(3):145-151, 2013. https://doi.org/10.5388/aon.2013.13.3.145