• Title/Summary/Keyword: per-less oscillation

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Possible involvement of temperature-entrainable timing system in arrhythmic mutant flies in Drosophila melanogaster

  • Yoshii, Taishi;Tomioka, Kenji
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.240-242
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    • 2002
  • In Drosophila melanogaster, it is known that the circadian clock consists of an autoregulatory feedback loop, which includes so-called clock genes, such as per, tim, dClk and cyc and produces periodical expression of per. It is recently suggested, however, that the circadian oscillation without the rhythmical expression of per is involved in the regulation of circadian locomotor rhythms. In the present study, we examined the existence and the property of the possible per-less oscillation using arrhythmic clock mutant flies carrying per$^{01}$, tim$^{01}$, dClk$^{Jrk}$ or cyc$^{01}$. When temperature cycles consisting of 25$^{\circ}$C and 30$^{\circ}$C with varying periods (T = 8~32 hr) were given, they showed rhythms synchronizing with the given cycle under constant darkness (DD). per$^{01}$ and tim$^{01}$ flies always showed a peak around 7 hr after the onset of thermophase irrespective of Ts of temperature cycles, while dClk$^{Jrk}$ and cyc$^{01}$ flies did not. In addition, several days were necessary to establish a clear temperature entrainment in per$^{01}$ and tim$^{01}$ flies, when they were transferred from a constant temperature to a temperature cycle under DD. These results suggest that per$^{01}$ and tim$^{01}$ flies have a temperature-entrainable weak oscillatory mechanism. The fact that dClk$^{Jrk}$ and cyc$^{01}$ flies did not show any sign of the endogenous oscillation suggests that the per-less oscillatory mechanism may require CLK and CYC.

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Sub-One volt DC Power Supply Expandable 4-bit Adder/Subtracter System using Adiabatic Dynamic CMOS Logic Circuit Technology

  • Takahashi, Kazukiyo;Yokoyama, Michio;Shouno, Kazuhiro;Mizunuma, Mitsuru
    • Proceedings of the IEEK Conference
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    • 2002.07c
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    • pp.1543-1546
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    • 2002
  • The expandable 4 bit adder/subtracter IC was designed using the adiabatic and dynamic CMOS logic (ADCL) circuit as the ultra-low power consumption basic logic circuit and the IC was fabricated using a standard 1.2 ${\mu}$ CMOS process. As the result the steady operation of 4 bit addition and subtraction has been confirmed even if the frequency of the sinusoidal supply voltage is higher than 10MHz. Additionally, by the simulation, at the frequency of 10MHz, energy consumption per operation is obtained as 93.67pJ (ar addition and as 118.67pJ for subtraction, respectively. Each energy is about 1110 in comparison with the case in which the conventional CMOS logic circuit is used. A simple and low power oscillation circuit is also proposed as the power supply circuit f3r the ADCL circuit. The oscillator operates with a less one volt of DC supply voltage and around one milli-watts power dissipation.

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A Dispersion Analysis for Minimum Grids in the Frequency Domain Acoustic Wave Equation (주파수영역 음향 파동방정식에서 최소 격자수 결정을 위한 격자분산 분석)

  • Jang Seong-Hyung;Shin Chang-Soo;Yoon Kwang-Jin;Suh Sang-Young;Shin Sung-Ryul
    • Geophysics and Geophysical Exploration
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    • v.3 no.2
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    • pp.39-47
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    • 2000
  • A great deal of computing time and a large computer memory are needed to solve wave equation in a large complex subsurface layers using the finite difference method. The computing time and memory can be reduced by decreasing the number of grid points per minimum wave length. However, the decrease of grids may cause numerical dispersion and poor accuracy. In this study we performed the grid dispersion analysis for several rotated finite difference operators, which was commonly used to reduce grids per wavelength with accuracy in order to determine the solution for the acoustic wave equation in frequency domain. The rotated finite difference operators were to be extended to 81, 121 and 169 difference stars and studied whether the minimum grids could be reduced to 2 or not. To obtain accuracy (numerical errors less than $1\%$) the following was required: more than 13 grids for conventional 5 point difference stars, 9 grids for 9 difference stars, 3 grids for 25 difference stars, and 2.7 grids for 49 difference stars. After grid dispersion analysis for the new rotated finite difference operators, more than 2.5 grids for 81 difference stars, 2.3 grids for 121 difference stars and 2.1 grids for 169 difference stars were needed. However, in the 169 difference stars, there was no solution because of oscillation of the dispersion curves in the group velocity curves. This indicated that the grids couldn't be reduced to 2 in the frequency acoustic wave equation. According to grid dispersion analysis for the determination of grid points, the more rotated finite difference operators, the fewer grid points. However, the more rotated finite difference operators that are used, the more complex the difference equation terms.

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The Effect of Exercise on Pulmonary Function (운동이 폐기능에 미치는 영향)

  • Park, Jae-Seuk;Kim, Youn-Seup;Choi, Eun-Kyoung;Jee, Young-Koo;Lee, Kye-Young;Kim, Keun-Youl;Chun, Yong
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.2
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    • pp.351-359
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    • 1998
  • Background: The effects of exercise on pulmonary function are complex and have been the subject of many investigations. But, there has been disputes about the effect of exercise on spirometric parameters and there is no study about the effect of exercise on IOS(Impulse Oscillometry)parameters. IOS, a new method of pulmonary function test, is based on the relationship between the pressure and flow oscillation which is produced by applying sinusoidal pressure oscillation to the respiratory system via the mouth. Method: Fifty-nine young adults without respiratory symptoms were divided into three groups according to degree of exercise(hard exercise group: mean exercise time is over three hours per week at least for the last one month, light exercise group : between thirty minutes to three hours, nonexercise group : less than thirty minutes) and undertaken pulmonary function test(simple spirometry and IOS). Results: The effects of exercise on spirometric parameters; percentage of predictive value of forced vital capacity(FVC % pred) was higher in hard exercise group than nonexercise group(hard exercise group: $102.4{\pm}14.8$, nonexercise group: $93.7{\pm}9.9$, p=0.017), but there was no significant difference in percentage of predicted value of forced expiratory volume in one second(FEV 1 % pred) and percentage of predicted value of forced expiratory flow 50% (FEF 50% pred) between groups. The effects of exercise on IOS parameters: Reactance at 5Hz(X5) was significantly lower in hard exercise group than nonexercise group(hard exercise group: $-0.166{\pm}0.123hPa/1/s$, nonexercise group: $-0.093{\pm}0.036hPa/1/s$, p=0.006) but there was no significant difference in central resistance(Rc), peripheral resistance(Rp), resonance frequency(RF) and resistance at 5Hz, 20Hz between groups. Conclusion: Hard exercise increased FVC % pred on spirometric parameters and decreased reactance at 5Hz(X5) on IOS parameters.

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Study on the Storage of Chestnut (밤 저장(貯藏)에 관(關)한 연구(硏究))

  • Yim, Ho;Kim, Choung-Ok;Shin, Dang-Wha;Suh, Kee- Bong
    • Korean Journal of Food Science and Technology
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    • v.12 no.3
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    • pp.170-175
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    • 1980
  • A mass production of chestnut necessiates the development of economic long-term storage method. The main objective of this study was to confirm the technical aspect of the chestnut storage method which was developed by two year project and to review the method of commercial application. The chestnut used for the experiments were separated in brine $(5.5{\sim}6.0^{\circ}\:B{\acute{a}}ume)$ into matured and unmatured lots and fumigated with $CS_2$ at a 5 $lb/27\;m^3$ level for $25{\sim}30\;hrs.$ The chestnuts were packed in wooden boxes with sawdust (50% moisture) in the ratio of 1 : 1 by volume. The boxes were stored in the cold room $(1{\pm}1^{\circ}C,\;85{\sim}95%\;RH)$ and the cellar ($0{\sim}10^{\circ}C$, controlled only by circulating night cool air). The results obtained were as follows: 1. Fully matured chestnut could be successfully preserved $8{\sim}9\;months$ at a l0% decay level in the cold room and $4{\sim}5\;months$ months in cellar. 2. Immatured chestnuts wire inferior to the matured in storage stability. At the maximum storage period, its storage life was two months shorter. 3. The heat transfer equation of piled chestnuts with sawdust can be suggested as $T_{\infty}-T_0=(T_{\infty}-T_0){\cdot}10^{-t/320}$ and j and $f_h$ values were 1 and 320 min, respectively. 4. The chestnuts in the package of storage unit had longer shelf life than naked chestnut during the retail distribution at ambient temperature.

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