• Title/Summary/Keyword: peak identification

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The Fingerprinting of Huangjinju Powder for Injection on Chinese Patent Medicine by XRD Fourier

  • Pan, Yan-Li;Zhang, Gui-Jun;Gong, Ning-Bo;Wu, Yun-Shan;Lu, Yang;Luo, Rong;Choi, Ho-Young
    • Korean Journal of Medicinal Crop Science
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    • v.14 no.2
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    • pp.117-123
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    • 2006
  • The purpose is to study the identification method of Huangjinju powder for injection and the medicinal materials by the fingerprint off-ray Diffraction Fourier (XRDF). We used the same method on both the studying of Huangjinju and the medicinal materials. Then we selected a few components alignment to compare. We analyzed the data by setting up the deviation $d({\AA})$ as ${\pm}0.05$ to calculate the rate of special mark on the sample (Px) and on the patent (P). The special XRDF of Huangjinju$[d({\AA})/(I/I_0)]$ have 5 peaks that have not expressed in medicinal materials. Therefore Px is 22.73%. Flos Trollii Chinensis has 3 special marks and Px is 17.65%. Flos Chrysanthemi Indici has 1 special mark and Px is 3.57%. Its coincided interplanar spacing with the patent is $2.907{\AA}$. Flos Lonicerae Japonicae has 6 special marks and Px is 23.08%. Its special mark in the patent are 4.95/14 and 4.50/15, respectively. The P is 9.09%. Its coincided interplanar spacing with the patent is $2.910{\AA}\;and\;3.05{\AA}$, respectively. The number of special XRDF mark peaks of baicalin is 9 and Px is 18.37%. Its coincided interplanar spacing with the patent is $2.910{\AA}$. It has visible mark and specificity adopting XRDF fingerprint to identify Huangjinju and medicinal materials. Establishing the quality standard is a synthetic index that depends both on special marks in the medicinal materials of the patent and on the coincidence peak data.

Source Identification of PM-10 in Suwon Using the Method of Positive Matrix Factorization (PMF 방법론을 이용한 수원지역 PM-10의 오염원 확인)

  • 황인조;김태오;김동술
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.2
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    • pp.133-145
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    • 2001
  • The receptor modeling is one of the statistical methods to achieve reasonable air pollution strategies. The pur-pose of this study was to survey the concentration variability oi inorganic elements and ionic species in the PM-10 particles, to qualitatively characterize emission sources by an advanced algorithm called positive matrix factoriza-tion(PMF) as a receptor model that can strictly provide results in every loading matrix. A total of 254 samples was collected by a PM-10 high volume air sampler from Mar. 1997 to Feb. 1998 in Kyung Hee University at Suwon Campus. Fourteen chemical species(Zn, Cu, Fe, Pb, Al, Mn, $Na^{+}$, NH$_4$+, $K^{+}$, $Mg^{2+}$, $Ca^{2+}$, $SO_4^{2-}$, $NO_{3}^{-}$, and $Cl^{-}$) were determined by AAS and IC methods. The study results showed that the average monthly concentration of PM-10 particles were 86.3$\mu\textrm{g}$/$\textrm{m}^3$ in March (maximum) and 28.5$\mu\textrm{g}$/$\textrm{m}^3$ in August(minimum), respectively. The concentrations of Na+, NH$_4$+, $K^{+}$ and $Cl^{-}$ in winter, $Mg^{2+}$, $Ca^{2+}$ and $NO_{3}^{-}$, in spring, and $SO_4^{2-}$ in summer showed the largest peak concentration for the respective season. Through and app-lication of a PMF program of Pm-10 concentration data of Suwon, 9 sources were qualitatively identified , such as incineration source, oil burning source, soil related source, open burning source automobile source, coal burning sources, secondary sulfate related source, and secondary nitrate related source.

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Copyright Protection for the Video image with Coded Watermarking (암호화 워터마킹을 사용한 비디오 영상의 저작권 보호)

  • Park, Young;Kim, Hang-Rae;Rhu, Ho-Joon;Kim, Jae-Won
    • Proceedings of the Korea Contents Association Conference
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    • 2003.11a
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    • pp.120-123
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    • 2003
  • In this paper, a digital watermarking scheme whichis effective in protecting a copyright of video image under an image transformation and impulse noise is proposed. The proposing scheme is to use a coded watermark that insert the personal ID of copyrighter. The recovery ability is improved by the coded watermark. Also the coded watermark is abel to trace the illegal distributors. Binary image is used as watermark image, the value of PSNR and recovered rates of watermark are obtained in order to confirm the required invisibility and robustness in watermark system. The experimental results show that image quality is less degraded as the PSNR of 98.21 ㏈. It is also observed that excellent watermark recovery is achieved under the image transformation and impulse noise.

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Identification of Major Metabolites of New Platinum(II) Complexes in Rats (새로운 백금 착체(II) 화합물의 흰쥐 혈장에서 대사체 확인)

  • Kim, Jong-Whan;Jo, Yo-Na;Rho, Young-Soo;Seo, Seong-Hoon;Jung, Jee-Chang;Chang, Sung-Goo;Lee, Kyoe-Heung;Lee, Joo-Han;Lee, Kyung-Tae
    • Journal of Pharmaceutical Investigation
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    • v.28 no.3
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    • pp.171-175
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    • 1998
  • KHPC-002 $[(trans-l-diaminocyclohexane-bis-l,2(diphenylphosphinoethane)platinum)\;{\cdot}2NO_3]$ and $KHPC-006[(cis-diaminocyclohexane-bis-1,2(diphenylphosphinoethane)platinum)\;{\cdot}2NO_3]$ were synthesized as candidates for third platinum antitumor agent. Before their pharmacokinetic study, we optimized the analytical condition with HPLC and identified the major metabolites in the rat plasma. HPLC analysis by $C_{18}$ reverse-phase column showed that standard peak of both compounds appeared rapidly at around 1 minutes, whereas metabolites of KHPC-002 and KHPC-006 which were extracted from plasma after single I.V. administration in rats or incubation for 24 hr at $37^{\circ}C$ showed retention time of $10{\sim}11$ minutes. These metabolites were identified as the major compound by Matrix Associated Laser Deposition/Ionization (MALDI), which only lose the 2 molecules of $NO_3$. Based on these results, we suggest that the major metabolites of KHPC-002 and KHPC-006 were [trans-l-diamino-cyclohexane-bis-l,2(diphenylphosphinoethane)platinum] and [cis-diaminocyclohexane-bis-l.2(diphenylphosphinoethane)platinum], respectively.

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Design of Biometrics System Using ECG Lead III Signals (심전도 신호의 리드 III 파형을 이용한 바이오인식)

  • Min, Chul-Hong;Kim, Tae-Seon
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.6
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    • pp.43-50
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    • 2011
  • Currently, conventional security methods including IC card or password type method are quickly switched into biometric security systems in various applications and the electrocardiogram (ECG) has been considered as one of novel biometrics way. However, conventional ECG based biometrics used lead II signal which conventionally used for formulaic signal to heart disease diagnosis and it is not suitable for biometrics since it is rather difficult to find consistent features for heart disease patents. To overcome this problem, we developed new biometrics system using ECG lead III signals. For wave extraction, signal peak points are extracted through AAV algorithm. For feature selection, extracted waves are categorized into one of four wave types and total twenty two features including number of vertices, wave shapes, amplitude information and interval information are extracted based on their wave types. Experimental results for thirty-six people showed 100% specificity, 95.59% sensitivity and 99.17% of overall identification accuracy.

Studies on Anopheles sinensis, the vector species of vivax malaria in Korea

  • REE Han-Il
    • Parasites, Hosts and Diseases
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    • v.43 no.3 s.135
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    • pp.75-92
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    • 2005
  • Extensive previous studies on taxonomy, behavior/bionomics and control of Anopheles sinensis are reviewed and summarized. Recent molecular identification revealed that the population of An. sinensis complex includes An. sinensis, An. pullus, An. lesteri and at least two new species, and An. yatsushiroensis is synonmy of An. pullus. An. sinensis is the main vector specie of vivax malaria in Korea. Larvae of An. sinensis breed in wide range of habitats which are naturally-made clean water, stagnant or flowing; main habitats include rice fields, ditches, streams, irrigation cannals, marshes, ponds, ground pools, etc. Their host preferences are highly zoophilic. Human blood rate is very low ($0.7-1.7\%$); nevertheless An. sinensis readily feeds on man when domestic animals are not found near by. They feed on hosts throughout the night from dusk to dawn with a peak period of 02:00-04:00 hours; they are slightly more exophagic (biting outdoors); much larger numbers come into the room when light is on. Main resting places are outdoors such as grasses, vegetable fields and rice fields. A mark-release-recapture study resulted that $37.1\%$ was recaptured within 1 km, $29.4\%$ at 1-3 km, $21.1\%$ at 3-6 km, $10.3\%$ at 6-9 km and $2.1\%$ at 9-12 km distance. An. sinensis hibernate outdoors (mostly under part of dense grasses) during October-March. At the end of the hibernation period (March-April) they feed on cows at daytime. Until today any single measure to effectively control An. sinensis population has not been found. Indoor residual spray with a long-lasting insecticide can not reduce vector population densities, but shorten their life spans in some degree, so contributes to malaria control.

Finite Element Model Updating and System Identification of Reinforced Concrete Specimen (철근콘크리트 실험체의 시스템 식별과 유한요소모델수정)

  • Kim, Hack-Jin;Yu, Eun-Jong;Kim, Ho-Geun;Lee, Sang-Hyun;Cho, Seung-Ho;Chung, Lan
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.647-652
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    • 2008
  • This paper focused on the application of finite element model updating technique to evaluate the structural properties of the reinforced concrete specimen using the data collected from shaking table tests. The specimen was subjected to six El Centro(NS, 1942) ground motion histories with different Peak Ground Acceleration(PGA) ranging from 0.06g to 0.50g. For model updating, flexural stiffness values of structural members(walls and slabs) were chosen as the updating parameters so that the converged results have direct physical interpretations. Initial values for finite element model were determined from the member dimensions and material properties. Frequency response functions(i.e. transfer functions), natural frequencies and mode shapes were obtained using the acceleration measurement at each floor and given ground acceleration history. The weighting factors were used to account for the relative confidence in different types of inputs for updating(i.e. transfer function and natural frequencies). The constraints based on upper/lower bound of parameters and sensitivity-based constraints were implemented to the updating procedure in this study using standard bounded variable least-squares(BVLS) method. The veracity of the updated finite element model was investigated by comparing the predicted and measured responses. The results indicated that the updated model replicates the dynamic behavior of the specimens reasonably well. At each stage of shaking, severity of damage that results from cracking of the reinforced concrete member was quantified from the updated parameters(i.e. flexural stiffness values).

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Finite Element Model Updating and System Identification of Reinforced Concrete Specimen (철근콘크리트 실험체의 시스템 식별과 유한요소 모델 수정)

  • Kim, H.J.;Yu, E.J.;Kim, H.G.;Chang, K.K.;Lee, S.H.;Cho, S.H.;Chung, L.
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.18 no.7
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    • pp.725-731
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    • 2008
  • This paper focused on the application of finite element model updating technique to evaluate the structural properties of the reinforced concrete specimen using the data collected from shaking table tests. The specimen was subjected to six El Centre (NS, 1942) ground motion histories with different peak ground acceleration (PGA) ranging from 0.06 g to 0.50 g. For model updating, flexural stiffness values of structural members (walls and slabs) were chosen as the updating parameters so that the converged results have direct physical interpretations. Initial values for finite element model were determined from the member dimensions and material properties. Frequency response functions (i.e. transfer functions), natural frequencies and mode shapes were obtained using the acceleration measurement at each floor and given ground acceleration history. The weighting factors were used to account for the relative confidence in different types of Inputs for updating (j.e. transfer function and natural frequencies) The constraints based on upper/lower bound of parameters and sensitivity-based constraints were implemented to the updating procedure in this study using standard bounded variable least-squares(BVLS) method. The veracity of the updated finite element model was investigated by comparing the predicted and measured responses. The results indicated that the updated model replicates the dynamic behavior of the specimens reasonably well. At each stage of shaking, severity of damage that results from cracking of the reinforced concrete member was quantified from the updated parameters (i.e. flexural stiffness values).

Identification of Brucella melitensis isolates originating from Mongolia and diagnostic real-time PCR evaluation using a specific SNP (몽골 유래 Brucella melitensis 동정 및 특이 SNP를 이용한 real-time PCR법에 의한 진단 평가)

  • Kang, Sung-Il;Kim, Ji-Yeon;Kim, Suk Mi;Lee, Jin Ju;Sung, So-Ra;Kim, Yeon-Hee;Jung, Suk Chan;Her, Moon
    • Korean Journal of Veterinary Research
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    • v.55 no.2
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    • pp.105-110
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    • 2015
  • A real-time PCR assay using hybridization probe (HybProbe) has been developed to detect Brucella (B.) melitensis strains. The primer and HybProbe sets were designed based on the gap gene of chromosome I with a specific single nucleotide polymorphism of B. melitensis. Specificity of the assay was confirmed by comparison to reference Brucella species and other related strains. In the melting curve analysis, B. melitensis generated a peak at $67^{\circ}C$ unlike those for other Brucella species observed at $61^{\circ}C$. Sensitivity of the assay for B. melitensis ranged from 20 ng to 200 fg of genomic DNA. The ability to identify 94 Mongolian B. melitensis isolates using the real-time PCR assay was identical to that of classical biotyping methods and differential multiplex PCR. These data showed that this new molecular technique is a simple and quick method for detecting B. melitensis, which will be important for the control and prevention of brucellosis.

Quantitative Analysis and Qualification of Acrylamide Using LC/ESI-MS (LC/ESI-MS를 이용한 Acrylamide의 정성확인 및 정량분석)

  • Park Chan-Koo;Jo Sung-Ja;Chough Nam-Joon;Kim Min-Young;Sohn Jong-Ryeul;Moon Kyong-Whan
    • Journal of environmental and Sanitary engineering
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    • v.19 no.4 s.54
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    • pp.25-33
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    • 2004
  • Acrylamide, difficult to analyze by GC and GC/MS due to the polarity and low volatility, was analyzed by LC/ESI/MS in the study. Acrylamide its(molecular weight 71amu) showed m/z=72 $(M+H)^+$ and high peak intensity at 22V in SIR mode. The mass spectrum ratios of acrylamide for qualitative identification had m/z=72 in precursor ion and m/z=55 in products ion, respectively. Those ratios at 30V in SIR mode ranged from 1: 1.4 to 1:1.17 despite various acrylamide concentrations. The ion intensity ratios of acrylamide $(m/z=72,\; [M+H]^+)$ to acrylamide isotopes $(m/z=73,\;[M+H]^+)$ ranged from 100 : 3.57 to 100 : 3.92. The results verified theoretical mass spectrum ratio that was 100:3.82. The linearity of standard calibration curve was y : 520.584x + 1815.26 with $r^2=0.99.$ In quality assurance and quality control, the recovery rate ranged from 81.64 percent to 90.97 percent and relative standard deviation was less than $10\%$ with 5 repeated injections at individual standard calibration solutions. The method was applied to analyze acrylamide in food at grocery stores. Snacks made of potatoes showed the highest acrylamide concentration followed by products made of French fries, wheat, and corn.