• 제목/요약/키워드: patterns of life course

검색결과 42건 처리시간 0.026초

Comparative Analysis of Growth-Phase-Dependent Gene Expression in Virulent and Avirulent Streptococcus pneumoniae Using a High-Density DNA Microarray

  • Ko, Kwan Soo;Park, Sulhee;Oh, Won Sup;Suh, Ji-Yoeun;Oh, TaeJeong;Ahn, Sungwhan;Chun, Jongsik;Song, Jae-Hoon
    • Molecules and Cells
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    • 제21권1호
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    • pp.82-88
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    • 2006
  • The global pattern of growth-dependent gene expression in Streptococcus pneumoniae strains was evaluated using a high-density DNA microarray. Total RNAs obtained from an avirulent S. pneumoniae strain R6 and a virulent strain AMC96-6 were used to compare the expression patterns at seven time points (2.5, 3.5, 4.5, 5.5, 6.0, 6.5, and 8.0 h). The expression profile of strain R6 changed between log and stationary growth (the Log-Stat switch). There were clear differences between the growth-dependent gene expression profiles of the virulent and avirulent pneumococcal strains in 367 of 1,112 genes. Transcripts of genes associated with bacterial competence and capsular polysaccharide formation, as well as clpP and cbpA, were higher in the virulent strain. Our data suggest that late log or early stationary phase may be the most virulent phase of S. pneumoniae.

기본 인명구조술 교육을 위한 CAI 코스웨어 개발 - 성인의 이물질에 의한 기도폐쇄를 중심으로 - (The development of CAl Courseware for Basic Life Support - Centered on the Foreign-Body Airway Obstruction in Adult-)

  • 김미선
    • 한국응급구조학회지
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    • 제7권1호
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    • pp.109-118
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    • 2003
  • With the rapid development of information and communication technology, a lot of multi-media learning programs are being developed and reported in the field of Emergency medicine both home and abroad. In this connection, this study was aimed at developing a foreign-body airway obstruction courseware in adults for EMT. The development period of CAI courseware lasted from May 2003 through November 2003. Among CAI courseware patterns, private instruction and repeat practice and simulation patterns were used as an instruction-learning strategy. The learning contents of the CAI courseware consisted of five chapters concerning (1) A relief of partial FBAO in the responsible victim, (2) A relief of complete FBAO in the responsible victim, (3) In case of unconsciousness in the responsible victim without removing all foreign body, (4) In case of consciousness in all victims after getting removed all foreign body and (5) A complete airway obstruction in victims without consciousness on the basis of assess responsiveness and the degree of airway obstruction. The way to use this courseware, with just a click on one specific chapter, was developed to proceed a course with progressive algorithm, a method of solving problems by choosing one between two situations. A characteristic of this CAI courseware is the enhanced efficiency of an instruction-learning method by providing an opportunity of choice based on situations in its effort to encourage learners to use a self-initiated learning method, not one-way method and to enhance problem solving skills among situations. Moreover, this courseware went through the diverse phases such as development, application, feedback in connection with learning process by practicing teachers, so that the courseware could be used frequently in the future. The contents of this courseware were written with the web, so that, if necessary, the contents could be continuously modified and complemented and handed out in the form of CD-ROM. This study indicates that the development of a variety of CAI courseware requires institutional and financial assistance and initiatives reflecting a reality in terms of learning process, technical assistance and resources.

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Meningococcal Disease and Quadrivalent MenACWY-CRM Vaccine (Menveo®)

  • Tsai, Theodore F.
    • Pediatric Infection and Vaccine
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    • 제19권3호
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    • pp.89-110
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    • 2012
  • Meningococcal Disease, manifesting as meningitis and septicemia, is a life-threatening bacterial infection that results in significant morbidity and mortality, particularly in childhood. Its epidemic potential and limited opportunities for clinical intervention due to its rapid course present unique public health and clinical challenges. Incidence is highest in infants and young children, with a secondary peak of risk in adolescents. Approximately 10% of cases are fatal and survivors can be left with serious and permanent sequelae including amputations, hearing loss and cognitive impairment. Transmission is only from human-to-human, by infected respiratory tract secretions or saliva and therefore crowding poses a tremendously elevated risk for disease development. Military recruits and university students are at high risk due to the high carriage rate in adolescents, their behavior patterns and close contact. Menveo$^{(R)}$ (Novartis Vaccines and Diagnostics), a novel quadrivalent meningococcal conjugate vaccine directed against meningococcal serogroups A, C, W-135 and Y, has been shown to be immunogenic and well tolerated in all age groups and was recently licensed for use in Korea. Recent cases and deaths among military recruits drew public attention to their elevated risk and the Korean government has recommended vaccination of all new military recruits. Many Korean students seek to attend school, university, or language institutes in countries where routine meningococcal vaccination is required - clinicians should be aware of such requirements to ensure that students are vaccinated prior to arrival in the destination country.

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부모역할행동에 미치는 복합적 영향들에 관한 고찰 (A Study on Multiple Influences on Parenting)

  • 전경숙
    • 한국생활과학회지
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    • 제5권2호
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    • pp.1-16
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    • 1996
  • This study has examined multiple influences of several variables on parenting behavior by looking into illustrative studies. This study provides support to the view that various factors influence parenting and that parenting behavior is multiply determined. Characteristics of parents, children and the context in which parent-child relations occur cause different childrearing patterns among parents. This study can be summarized as follows: 1) Parental behavior is influenced to a large degree by what the parent brings to the situation. In other words, characteristics of the parent including personality characteristics, interpersonal skills, problem-solving skills, level of maturity, values and childrearing beliefs contribute to individual differences in parenting. 2) The parent's relationship history influences the personality characteristics that the parent brings to his or her adult roles. To understand who the parent is today, we have to look at who the parent was, and what the parent was doing in the years prior to parenthood. That is, we need to see the life course of the individual before parenthood. 3) Contextual variables including the immediate context and the larger context have proved to influence parental behaviors. Characteristics of the immediate context such as the quality of marital rationship can influence the parent's psychological well-being and his or her behavior toward the childen while characteristics of the larger context such as the economic situation and the neighborhood can influence the level of stress experienced by the parent and cosequently how the parent relates to his or her child. 4) In order to understand the development of the parent-child relationship we need to look at the characteristics of the child. Children may elicit positive behaviors from their parents, or they may possess characteristics that the parents find aversive thus leading to difficulties in the relationship. Therefore, much depends on the fit beween the characteristics of the parents and characteristics of the child. By examining multiple contemporaneous influences on parenting, this study could deepen the understanding of why parents have different childrearing patterns, why some parents fail to meet their children's demands and why parents act in certain ways. What we ultimately hope is that as we learn more about parenting and the development of parent-child relationships, we will be better able to provide parents with the supports they need to achieve their parenting goals.

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청소년기 장신구 착장에 관한 연구 - 라이프스타일과 의복행동을 중심으로 - (A Study on the Ornaments Wear of Adolescents - Focusing on the Life Style and Clothing Behavior -)

  • 최은영;전경란
    • 한국생활과학회지
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    • 제9권1호
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    • pp.137-152
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    • 2000
  • The purpose of this study was to investigate the disposition of adolescents in their ornament wearing pattern associate with their life style and clothing behavior. The subject of this study consists of 345 middle and high school girls living in Chung-Nam Province and Taejon Metropolitan City. SPSS/PC+ program was utilized to calculated frequency(N), mean value(M) and standard deviation(SD) for statistical analysis. Differences among the populations were examined through f test, ANOVA. The results of this study reveals that the ornaments wearing patterns are significantly different according to their life style and clothing behavior as follows: 1. Correlation between the wear of ornaments and the life style: School girls who pursue the modernistic life style prefer the fashionable ornaments (e.g. sunglasses) and they are always in contact with the latest information. On the contrary, school girls who pursue the practical life style emphasize on the practical use when they purchase the ornaments, e.g. umbrella. School girls having romantic or passive nature have a preference for the brand name and brand image of the ornaments and they in general would like to buy ornaments such as the bracelets. 2. Correlation between the wear of ornaments and the clothing behavior: School girls having sympathetic nature and being deeply interested in clothing put a stress on the latest fashion of the ornaments. They usually want to buy fashionable ornaments such as the cellular phone, beeper and sunglasses. Subjects who estimate themselves by their garments are sensitive to the price of the ornaments while aesthetes emphasize the brand image of the ornaments. Chaste school girls put their emphasis on the quality of the ornaments and they most want to have functional hair bands. Following suggestions can be made based on the discussions above: It is necessary for us to have correct understanding about the correlation between the ornaments and clothing of school girls in order to lead them to have appropriate clothing behavior. Furthermore, it is required to construct a bridge linking a course of study to rational habits guidance which will provide us more appropriate tools for clothing behavior guidance.

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서울시 공공자전거 공유시스템(PBSS)의 시공간적 이용 패턴 분석 - 서울시 여의도동을 중심으로 - (Spatio-Temporal Patterns of a Public Bike Sharing System in Seoul - Focusing on Yeouido District -)

  • 윤승용;민경훈;고하정
    • 한국조경학회지
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    • 제48권1호
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    • pp.1-14
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    • 2020
  • 세계적으로 공공자전거 공유시스템(PBSS) 및 프로그램(PBSP)이 증가하면서 다양한 정책과 연구들이 진행되었다. 오늘날 PBSS가 일상생활에서 밀접하게 이용되면서 다양한 현상과 수요가 발생하고 있으나, 아직 국내에서는 통근통학에 초점을 맞춘 정책과 연구들이 주로 이루어지고 있다. 이에 본 연구는 다양한 PBSS 수요를 파악하기 위해서 서울시 여의도를 대상으로 2018년도 한 해 동안 발생한 PBSS 이용 데이터를 분석하여 이용 패턴을 유형화하고 특징을 분석하였다. 서울시에서 제공하는 PBSS 자료를 기반으로 주중/주말 이용률에 따라 대여소를 3개 유형으로 구분하여 각각의 특징을 분석하였다. 여의도의 PBSS는 이용량의 경우에는 서울시 전체에서 4.3%, 대여소 개소수의 경우에는 2%에 해당하는 것으로 나타났다. 주중 이용률이 높은 대여소는 다른 유형에 비하여 사계절 모두 높은 이용률을 보였으며, 업무 및 주거지역에 주로 분포하였다. 주말 이용률이 높은 대여소의 경우에는 봄(4~5월)과 가을(9~10월)에 집중된 이용 패턴이 나타났으며, 대여소에서 공원입구까지의 거리가 가까운 것으로 나타났다. 또한, 주중 이용률이 높은 패턴에 비해서 동일한 대여소를 통해 대여 및 반납이 이루어진 경우가 많고, 특정 대여소에 PBSS 이용이 집중된 쏠림현상이 나타나고 있는 것을 확인할 수 있었다. 따라서, 획일적인 PBSS 운영보다는 대여소별로 다양한 이용수요와 현상을 반영한 PBSS의 관리와 프로그램이 운영되어야 할 것이다. 본 연구결과는 PBSS 이용에 대한 수요를 유형에 따라 시공간적으로 파악함으로써 효과적인 PBSS 운영이 이루어질 수 있도록 기초자료를 제공하는 것에 의의가 있다.

농가소득(農家所得) 증대(增大)를 위한 한계농지(限界農地)의 효율적(效率的) 이용방안(利用方案) - 농지(農地) 및 환경보존(環境保存)을 중심으로- (A Study on Efficient Utilization of the Idle & Marginal Farm Land for Farm Household Income Increase - With Respect to Conservation of Farm Land and Sustainable Environment -)

  • 임재환
    • 농업과학연구
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    • 제22권1호
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    • pp.110-126
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    • 1995
  • Korean economy has been developed successfully in the course of implementing the five year economic development plans since 1962. The gap of incomes and quality of life between rural and urban area has been widened and it made rural farm laborers drain to urban areas. Therefore the prevailing situation of labor shortage and wage hike in rural area has made farm management deteriorate in recent years. Under the internal and international unfavorable economic conditions, marginal farm land of 66.5 thousand ha has been idled as of end of 1993. The total area outside agricultural development zone with bad farming conditions including irrigation and drainage, and land consolidation for mechanization were estimated at 360.4thousand ha equivalent to 17.5% of the total farm land area in Korea. Considering the topographical conditions of marginal lands, the effective use of marginal lands should be studied from the view point of public interest rather than from the view point of individual economic conditions. Considering the present agricultural economic settings, such as price decrease, unfavourable benefits of farm products, labour shrotage, free trade of farm products and poor physical condition of marginal lands, the institutional and realistical measures for the effective utilization of idle and marginal land should be studied as soon as possible. Detail land use pattern should be surveyed in the areas outside agricultural development zone and have to be classified as orchard farms, grass land, fish culture farms, lawn and ornamental tree farm, sight seeing and leisure farms for urban peoples, special crops production farms and common farms to be developed for farm mechanization. According to the surveyed results, the expected utilization patterns of the idle and marginal lands could be considerd as village common use, farm land base development, leisure farm development, mutual complementary utilization between urban and rural areas, G't purchase and management, credit supply and new extension services, improvement of cropping patterns and sight seeing and leisure farm patterns. For the successful and reasonable management of the marginal lands, the actions such as institutional improvement, prohibition of idle marginal land, enforcement of activities of farm management committee members and land banking system of RDC including development and utilization systems should be included.

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노인의 다중적 건강 변화궤적 유형화 및 관련요인 탐색 (Multidimensional Health Trajectories and Their Correlates Among Older Adults)

  • 배다영;박은빈
    • 한국가정과교육학회지
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    • 제33권4호
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    • pp.31-48
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    • 2021
  • 본 연구는 고령화연구패널조사(KLoSA)의 1-6차 연도 자료를 분석하여 노년기의 우울, 만성질환, 인지기능의 다중적 측면에서의 건강 변화 유형을 파악하고 이와 관련이 있는 요인들을 분석하고자 하였다. 연구의 대상은 1차 연도 조사 시점에서 65세 이상이고 결측률이 없는 총 2,059명이다. 잠재성장모형을 통해 세 가지 건강 측면이 시간에 따라 어떠한 변화궤적을 보이는지 살펴보았으며, 성장혼합모형을 활용해 세 건강 요인에서 서로 다른 변화 궤적을 보이는 집단들을 유형화하였다. 또한 일원분산분석 및 Scheffé 사후검증, 교차분석을 통해 건강 변화유형 집단에 따라 인구사회학적 특성, 건강행동, 삶의 만족도에서 차이가 나타나는지를 살펴보았다. 본 연구의 주요 결과는 다음과 같다. 첫째, 잠재성장모형 분석 결과 우울과 만성질환의 수는 연령에 따라 점차 증가하고 인지기능은 점차 감소했다. 둘째, 성장혼합모형을 분석한 결과 노인의 건강 변화는 일반적 노화, 질환 증가, 만성적 문제의 세 집단으로 유형화되었다. 셋째, 노인의 인구사회학적 특성, 건강행동, 삶의 만족도는 세 집단에 따라 유의한 차이가 나타났다. 특히 만성적 문제 집단의 경우 교육 및 소득수준이 낮고, 전반적으로 낮은 삶의 만족도를 나타냈다. 본 연구는 노년기 건강증진 교육 프로그램에 있어 노인들이 경험하는 건강의 다중적 측면을 고려하는 것이 중요함을 보여주며, 노년기 건강증진 교육 프로그램을 위한 제언을 제공한다. 또한 전생애적 건강관리를 위한 건강정보문해력 증진에 있어서 가정과 교과과정이 갖는 중요성에 대해 논의하고자 한다.

객사(客舍) 누각(樓閣)의 기능 및 공간성 변화 - 밀양(密陽) 영남루(嶺南樓)를 대상으로 - (A Study on the Changes of the Government Pavilion, Miryang Yeongnamnu in terms of Function and Spatiality)

  • 류성룡
    • 대한건축학회논문집:계획계
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    • 제34권8호
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    • pp.69-76
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    • 2018
  • This study is basically about the changing appearance of the big pavilion, Yeongnamnu in Miryang city belonging to the government guesthouse of Joseon dynasty. And the purpose of this study confirms that even if the appearance of the building has not changed, the function of the building changes because the reason why people think about the building is also different. First, looked at the appearance of architecture and the function of architecture that changes with the times. In the course of the research, the changes of pavilion were traced by dividing it into five from Kory? dynasty which was first established to the present. Then, tried to find out the change patterns by analyzing important events related to buildings or places in each period. As a result, the following facts were confirmed. 1. Because of the Buddhist repression policy in Joseon Dynasty, the Yeongnamnu changed from the temple pavilion to the government pavilion. 2. Throughout the Joseon Dynasty, Yeongnamnu was the representative scenic of Miryang City. 3. In the late Joseon Dynasty, Yeongnamnu was famous as a place where a woman named Arang devoted her life in order to preserve his fidelity. 4. Since 1910, Yeongnamnu has become an important cultural asset, and space has been widely used as a venue for various public events. 5. From 1945 to 1999, Yeongnamnu was used mainly for the events of Arang Remembrance and Miryang Culture Festival. And the inner space of Yeongnamnu was rarely used because people thought preservation is important.

공간관의 변화에 따른 사건과 장소의 관계 유형에 관한 연구 (A Study on Relative Type of Events and Place relevant to Change of Spatial View)

  • 황용섭;김주연
    • 한국실내디자인학회논문집
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    • 제18권2호
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    • pp.25-32
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    • 2009
  • To the human being, the space as the objective for fundamental thought called 'Being', and the space as the place for actual experience containing 'Life and Experience', have coexisted. Such dual characteristics owned by the space have come to the present creating various spatial viewpoints. As for the space as the objective for various thoughts and interpretations, its emphasis is nowadays being moved to the existence from such being. There is the event in the core of such change. Human's recognition for the space is originated from the observed events, which appears as an immense meaning, as it 'is accumulated as the experience. Therefore, the importance of the event in another viewpoint thinking the space is becoming bigger. This research has tried to grasp the tendency for the place-orientation by grasping the meaning owned by the event through the course that the viewpoint for such space has been changed. This research put its focus on clarifying the relationship between the place and event that are brought into relief by tracking down the transitional process of the viewpoint of space in the history of Occidental philosophy. Through this process, this research came to have a grip on the relationship in which a sense of place obviously stands out in bold relief as a result of an event, an emblem of an event, condition of an event, and as an event itself. Such four patterns are not mutually individual phenomenon, but form a discourse on modern space by traversing each other crisscross.