Using superoxide dismutase (SOD)-deficient mutants of Saccharomyces cerevisiae, the oxygen toxicity induced by paraquat was studied. In aerobic culture condition, yeasts lacking MnSOD (milochondrial SOD) showed more significant growth retardation than CuZnSOD (cytoplasmic SOD)-deficient yeasts. However, not so big differences in growth pattern of those mutants compared with wild type were observed under anaerobic condition. When exposed to paraquat, the growth of yeasts lacking CuZnSOD was severely affected by higher than 0.01mM of paraquat in culture medium. By the analysis of several cellular components ivolved in free radical generating and scavenging system, it was found that, under aerobic condition, the content of lipid peroxides in cell membrane as well as cellular activity of glutathion peroxidase of CuZnSOD-deficient mutants was increased in the presence of paraquat, although significant decrease of catalase activity was observed in those stratns. In MnSOD-deficient yeast, however, increment in cellular activity of glutathion peroxldase and catalase by paraquat was observed without any deterioration of membrane lipid. It implies that the lack of mitochondrial SOD could be compensated by both of glutathion peroxldase and catalase, but that only glutathion peroxidase might act for CuZnSOD in cytoplasm. In contrast, all of SOD-deficient mutants showed a significant decrease in catalase activity, but slight increase in the activities of glutathion peroxidase, when cultivated anaerobically in the medium containing paraquat. Nevertheless, any significant changes of lipid peroxides in cell membranes were not observed during anaerobic cultivation of SOD-deficient mutants. It suggests that a little amount of free radicals generated by paraquat under anaerobic condition could be sufficiently overcome by glutathion peroxidase but not by catalase.
Journal of the Korean Institute of Traditional Landscape Architecture
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v.40
no.4
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pp.32-48
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2022
This study analyzed the construction pattern and historical reality of Gwallamji Pond(觀纜池) in the rear garden of Changdeokgung Palace(昌德宮), which has been received as distorted information and has not received sufficient attention. The main topics consisted of the construction period and reorganization in the pond garden, changes in the installed wooden bridge, the existence of the berthing facility, and whether the plan shape was deformed. The main results of this study can be summarized as follows. First, the Gwallamji Pond was already completed before the Gapsin Coup, which occurred in the year of King Gojong. Since then, the Gwallamji Pond area, including the surrounding facilities, has been neglected for a while and was extensively renovated in the early 1900s. It is difficult to find a clear basis for the suspension and resumption of the Gwallamji Pond construction proposed in the previous discussion. Second, three types of wooden bridges with different shapes and structures were installed sequentially in the Gwallamji Pond. In particular, the second wooden bridge, which installed after the maintenance of the Gwallamji Pond, is judged to be the pontoon bridge depicted in Donggweoldohyeong(東闕圖形), and the railing of the bridge was decorated to symbolize the imperial family of the Korean Empire. The third wooden bridge, which appeared intensively in Japanese colonial era, was a Japanese-style bridge. Third, a berth facility for boarding and disembarking existed on the eastern shore of the Gwallamji Pond. The berth facility is also described in Donggweoldohyeong and it remained until the Japanese colonial period. However, as the maintenance work of the Gwallamji Pond was carried out several times after liberation, the berth facility was gradually damaged, and there are no traces left now. Fourth, The Gwallamji Pond was originally constructed in a planar shape of the Korean Peninsula similar to the present. It is necessary to reconsider the conventional theory that the Gwallamji Pond, made in the shape of a gored-shaped bottle, was renovated in the shape of the Korean Peninsula in Japanese colonial era. Even when the term Pandoji Pond(半島池) first appeared, there was no view that the Japanese intentionally modified the Gwallamji Pond.
The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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v.9
no.1
/
pp.1-12
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2004
Sedimentary facies and high-resolution echo facies were analyzed to elucidate sedimentation pattern of the late Quaternary glacial-marine deposits in the northern continental margin of the South Shetland Islands. Six sedimentary facies are classified, based on grain texture and sedimentary structures in gravity cores. The high-resolution (3.5 ㎑) echo characters are classified into 6 echo facies on the basis of clarity, continuity, and shape of bottom and subbottom echoes together with seafloor topography. Distribution of the echo and sedimentary facies suggest that there was a significant change in sedimentation pattern between the Last Glacial Maximum (LGM) and subsequent glacier-retreating period. When the grounded glaciers extended to the present shelfbreak during LGM, coarse-grained subglacial tills were widespread in the shelf area, and deep troughs in the shelf were carved beneath the fast-flowing ice steam. As the glacial margin retreated landward after LGM, dense meltwater plumes released from the retreating ice-front were funneled along the glacier-carved troughs, and accumulated channel- or cannyon-fill deposits in the shelf and the upper to mid slope. At that time, slope sediments seem to have been reworked by slope failures and unsteady contour currents, and further transported by fine-grained turbidity currents along the South Shetland Trench. After the glacial retreat, sediments in the shelf and slope areas have been mainly introduced by persistent (hemi) pelagic settling, and fine-grained turbidity currents frequently occur along the axis of the South Shetland Trench.
The aim of this study is to evaluate tennis shoes's plantar pressure distribution in tennis prayers and to determine the influence of the shoe on various tennis movements. When investigating the biomechanics of movement in tennis, one of the first things to do is to understand the movement patterns of the sport, specifically how these patterns relate to different tennis shoes. Once these patterns are understood, footwear company can design tennis shoes that match the individual needs of tennis players. Plantar pressure measurement is widely employed to study foot function, the mechanical pathogenesis for foot disease and as a diagnostic and outcome measurement tool for many performance. Measurements were taken of plantar pressure distribution across the foot and using F-Scan(Tekscan Inc.) systems respectively. The F-Scan system for dynamic in-shoe foot pressure measurements has enabled us to assess quantitatively the efficacy of different types of footwear in reducing foot pressures. The Tekscan F-Scan system consists of a flexible, 0.18mm thick sole-shape having 1260 pressure sensors, the sensor insole was trimmed to fit the subjects' right, left shoes. For this study 4 university male, high level tennis players were instructed to hit alternated forehand stroke, backhand stroke, forehand volley, backhand volley, smash, service movement in 4 different tennis shoes. 1. When impact in tennis movement, peak pressure distribution of landing foot displayed D>C>B>A, A displayed the best low pressure distribution. A style's tennis shoes will suggest prayer with high impact. If prayer with high impact feeling during pray in tennis wear A style, it will decrease injury, will have performance improvement. 2. When impact in tennis movement, plantar pattern of pressure distribution in landing foot displayed B>A>C>D in stability performance. During tennis, prayer want to stability movement suggest B style tennis shoes when tennis movement impact keep stability of human body. B style tennis shoes give performance improvement 3. When impact in tennis movement, plantar pattern of center of force(C.O.F.)trajectory in landing foot analyzed this : 1) When stroke movement and volley movement in tennis, prayer better to rearfoot movement. 2) when service movement, prayer midfoot strike movement. 3) when smash movement, prayer have forefoot strike movement.
'Heaundae Woosin Building' fire was the case that a fire breaking out on the $4^{th}$ floor spread out the $38^{th}$ floor which is a top story and the penthouse was destroyed by fire. After this fire, the fire safety for high rise buildings has been on the rise and several new laws and regulations related in the buildings were created. The study is to analyze Heaundae officetel building case using FDS which is one of the CFD programs for fire. The methodology of this study is to analyze the case comparing with fire spread and route from a virtual fire simulation and related articles and a video clip of actual scene fire. This study shows that a fire spreading on top of levels spent approximately 30 minutes and, which is similar to the actual fire case. Also the pattern of spread has similarity with the case. However, even if the actual fire case shows the fire pattern was "V shape", the smoke-view presents the fire dose not spread horizontally as much as the real fire case. The result shows uncertainty of the modeling based on many grids and a limitation of putting interior finish input sources and the direction of the wind might cause the difference. Also, to analyze factors influencing on a vertical fire, another fire modeling is performed by in condition of modeling environment considering concrete interior finish between buildings and no wind. The result presents the fire spread in smoke-view does not spread vertically as much as the actual case.
To examine the materials, production techniques, and key features of Goryeo wooden lacquerwares, scientific analysis was conducted on six relevant lacquerware items. All of the items, except for a lacquered bowl duksu 4123, were found to have been made by first covering the surface of the wood with cloth and then varnishing with lacquer. The wooden frames of flower-shaped lacquered case and pine leaves shape lacquered case were made by wrapping thin wood around either the lid or bottom panel. In most cases, microscopic analysis revealed a lower layer of lacquer mixed with bone ash and bone dust, followed by an upper varnish layer of lacquer. SEM-EDS analysis and μ-XRF Micro-X-ray Fluorescence analysis showed that vermilion lacquer mixed with cinnabar was used on the surface. A lid decorated with a dot pattern was made by first varnishing the surface with yellow lacquer mixed with orpiment, and then irregular dot pattern with a mixture of black lacquer and soot. The vermilion lacquer used to varnish the side of the lacquered bowls was composed of lacquer mixed with cinnabar and minium Red Lead.
Since the restoration or masticatory function is the most important aim of implants, it should be substituted for the role of natural teeth and deliver the stress to the bone under the continous load during function. In natural teeth, stress distribution can be obtained through enamel, dentin and cementum and the elasticity of the periodontal ligament play a role of buffering action. In contrast, implant prosthesis has a very unique characteristics that it delvers the load directly to bone through the implant and superstructure. This fact arise the needs to evaluate the stress distribution of the implant in the mechnical aspects, which has a similar role of natural teeth but different pathway of stress. With 3 kinds of implant in prevalent use, 2 types of experimental PEA implant models were made, axisymmetric and 2-dimensional type. In axisymmetric model, the stiffness of the part including the prosthesis and implant which extrude out of bony surface could be calculated with displacement of the superstructure un er 100N vertical load and then damping effects could be determined through this stiffness. In axisymmetric FEA model, load to the bone could be deduced by evaluation the stress distribution of the designed surface under the 100N vertical force and in 2-dimensional model, 100N eccentric vertical load and 20N horizontal loda. The result are as follows. 1. In every implant, stress to the bone tends to be concenturated on the cortical bone. 2. Though the stress of the cancellous bone is larger at the apex of implants, it is less compared with cortical bone. 3. Under 20N horizontal load, stress of the left and right sides of implant shows a symmetrical pattern. But under 100N eccentric vertical load, loaded side shows much larger stress value. 4. In the 1mm interface, stress distribution among implants tend to have a similar pattern. But under 20N horizontal load apposite side of being loaded shows less stress in IMZ. 5. In the case of screw type implant, stress tends to vary along with screw shape. 6. According to the result determined with microstrain, cancellous bone id generally under the condition of overload, while cortical bone is usually within the limitation of physiologic load. 7. In the Branemark implant, maximum stress to the cortical bone is larger than any other implant except for the condition of 20N horizontal force and 0.05mm interface. 8. Damping effects of implants is maximum in IMZ.
The microscopic characteristics and cellulose structures of primary and secondary tissues in Pinus densiflora S. et Z. were examined. Cells of primary tissue in cross section showed an irregular arrangement and round shape. Fiber lengths were 200 to $250{\mu}m$ in primary tissue, and 1,500 to $1,600{\mu}m$ in secondary tissue. Cell diameters in primary tissue were larger than those in secondary tissue; 40 to $50{\mu}m$ in former and 10 to $20{\mu}m$ in latter. Crystallite width and d-spacing of (200) in both tissues did not show any significant differences. However, crystallinity indices by Segal's method showed significant differences as 23% in primary tissue and 35% in secondary tissue. In the orientation of cellulose microfibril, primary tissues had a random pattern, whereas, secondary tissues presented an oriented pattern with 20 to 30 degree. The cellulose crystalline of primary tissue was easily transformed into cellulose II by mercerization, but that of secondary tissue hardly transformed. It is considered that the difference of crystal transformation in both tissues could be caused by the difference of lignification.
Park, So Hyun;Choi, Jinhyun;Kim, JinSung;Ahn, Sohyun;Kim, Min Joo;Lee, Ho;Choi, Seo Hee;Park, Kwangwoo
Progress in Medical Physics
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v.29
no.1
/
pp.1-7
/
2018
The $TomoTherapy^{(R)}$ beam-delivery method creates helical beam-junctioning patterns in the dose distribution within the target. In addition, the dose discrepancy results in the particular region where the resonance by pattern of dose delivery occurs owing to the change in the position and shape of internal organs with a patient's respiration during long treatment times. In this study, we evaluated the dose pattern of the longitudinal profile with the change in respiration. The superior-inferior motion signal of the programmable respiratory motion phantom was obtained using AbChes as a four-dimensional computed tomography (4DCT) original moving signal. We delineated virtual targets in the phantom and planned to deliver the prescription dose of 300 cGy using field widths of 1.0 cm, 2.5 cm, and 5.0 cm. An original moving signal was fitted to reflecting the beam delivery time of the $TomoTherapy^{(R)}$. The EBT3 film was inserted into the phantom movement cassette, and static, without the movement and with the original movement, was measured with signal changes of 2.0 s, 4.0 s, and 5.0 s periods, and 2.0 mm and 4.0 mm amplitudes. It was found that a dose fluctuation within ${\pm}4.0%$ occurred in all longitudinal profiles. Compared with the original movement, the region of the gamma index above 1 partially appeared within the target and the border of the target when the period and amplitude were changed. Gamma passing rates were 95.00% or more. However, cases for a 5.0 s period and 4.0 mm amplitude at a field width of 2.5 cm and for 2.0 s and 5.0 s periods at a field width of 5.0 cm have gamma passing rates of 92.73%, 90.31%, 90.31%, and 93.60%. $TomoTherapy^{(R)}$ shows a small difference in dose distribution according to the changes of period and amplitude of respiration. Therefore, to treat a variable respiratory motion region, a margin reflecting the degree of change of respiration signal is required.
Journal of Korean Tunnelling and Underground Space Association
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v.6
no.3
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pp.213-225
/
2004
The number of tunnels are in fact increasing as a part of linear improvement project of general national highway and road enlargement and pavement project. Recently, collapses of portal slope are also occurring considerably, due to local raining from severe rain storm and abnormal weather. Accordingly, it was risen a necessity to efficiently respond to tunnel portal slope damage and maintenance in Korea and oversea nations. This paper is a basic proposal to execute a survey on the current status and state of the tunnel portal slopes that were already installed and are now being operated along general national highways, and also to execute state evaluation for the purpose of managing those effectively. As a research method, domestic tunnels were analyzed in accordance with geometrical shape such as access type, portal form, and tunnel type, etc. via field survey to analyze the types of tunnel portal slopes along national highways. State evaluation classification sheet is presented to divide classes for the danger state of the surveyed portal slopes, and then the related grades are divided. It is mainly aimed at classifying the tunnel portal slope along national highways with using this state evaluation, to use it as basic data so that continuous maintenance can be executed in the future in accordance with danger classes.
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