• Title/Summary/Keyword: pattern discovery

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Design, Combinatorial Library Synthesis and Biological Evaluation of Nonpeptide Scaffold for Beta Turns

  • Im, I-Sak;Thomas R.Webb;Dona Chianelli;Kim, Yong-Chul
    • Proceedings of the PSK Conference
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    • 2003.10a
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    • pp.91-91
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    • 2003
  • The beta-turn has been implicated as an important conformation for biological recognition of peptides or proteins. We adapted the concept of general Ca atom positioning from the cluster analysis and recombination of each ideal beta-turn conformation pattern by Garland and Dean (1. Computer-Aided Molecular Design, 1999, 13, 469) as one strategy of designing non-peptide beta-turn scaffolds. (omitted)

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A Study on the Method of Combining Empirical Data and Deterministic Model for Fuel Failure Prediction (핵연료 파손 예측을 위한 경험적 자료와 결정론적 모델의 접합 방법)

  • Cho, Byeong-Ho;Yoon, Young-Ku;Chang, Soon-Heung
    • Nuclear Engineering and Technology
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    • v.19 no.4
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    • pp.233-241
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    • 1987
  • Difficulties are encountered when the behavior of complex systems (i.e., fuel failure probability) that have unreliable deterministic models is predicted. For more realistic prediction of the behavior of complex systems with limited observational data, the present study was undertaken to devise an approach of combining predictions from the deterministic model and actual observational data. Predictions by this method of combining are inferred to be of higher reliability than separate predictions made by either model taken independently. A systematic method of hierarchical pattern discovery based on the method developed in the SPEAR was used for systematic search of weighting factors and pattern boundaries for the present method. A sample calculation was performed for prediction of CANDU fuel failures that had occurred due to power ramp during refuelling process. It was demonstrated by this sample calculation that there exists a region of feature space in which fuel failure probability from the PROFIT model nearly agree with that from observational data.

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Overview of Fuzzy Associations Mining

  • Chen, Guoqing;Wei, Qiang;Kerre, Etienne;Wets, Geert
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2003.09a
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    • pp.1-6
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    • 2003
  • Associations, as specific forms of knowledge, reflect relationships among items in databases, and have been widely studied in the fields of knowledge discovery and data mining. Recent years have witnessed many efforts on discovering fuzzy associations, aimed at coping with fuzziness in knowledge representation and decision support processes. This paper focuses on associations of three kinds, namely, association rules, functional dependencies and pattern associations, and overviews major fuzzy logic extensions accordingly.

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A Study on Customer's Purchase Trend Using Association Rule (연관규칙을 이용한 고객의 구매경향에 관한 연구)

  • 임영문;최영두
    • Proceedings of the Safety Management and Science Conference
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    • 2000.11a
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    • pp.299-306
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    • 2000
  • General definition of data mining is the knowledge discovery or is to extract hidden necessary information from large databases. Its technique can be applied into decision making, prediction, and information analysis through analyzing of relationship and pattern among data. One of the most important work is to find association rules in data mining. The objective of this paper is to find customer's trend using association rule from analysis of database and the result can be used as fundamental data for CRM(Customer Relationship Management). This paper uses Apriori algorithm and FoodMart data in order to find association rules.

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Prediction of Deficiency Pattern in Diabetic Patients Using Multi-frequency Bioimpedance Resistance (다주파수 생체임피던스 저항을 이용한 당뇨병 환자의 허증 변증 예측)

  • Kim, Kahye;Kim, Seul Gee;Cha, Jiyun;Yoo, Ho-Ryong;Kim, Jaeuk U.
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.3
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    • pp.94-99
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    • 2022
  • The discovery of biomarkers related to pattern identification (PI), the core diagnostic theory of Korean medicine (KM), is one of the methods that can provide objective and reliable evidence by applying PI to clinical practice. In this study, 40 diabetic patients and 41 healthy control subjects recruited from the Korean medicine clinic were examined to determine the human electrical response related to the deficiency pattern, a representative pattern of diabetes. Qi-Blood-Yin-Yang deficiency pattern scores, which are representative deficiency patterns for diabetes mellitus, were obtained through a questionnaire with verified reliability and validity, and the human electrical response was measured non-invasively using a bioimpedance meter. In ANCOVA analysis using gender as a covariate, the 5 kHz frequency resistance and 5-250 kHz frequency reactance were significantly lower in the diabetic group than in non-diabetic control group. In addition, the multiple regression analysis showed a positive correlation (R2=0.11~0.19) between the Yang deficiency pattern score and resistance value for the diabetic group; the correlation was higher at higher frequencies of 50kHz (R2=0.18) and 250kHz (R2=0.19) compared to 5kHz(R2=0.11). In contrast, there was no such significant association in the control group. It implies that bioimpedance resistance measured at finite frequencies may be useful in predicting Yang deficiency, which is closely related to diabetic complications by reflecting the decrease in body water content and metabolism. In the future, large-scale planned clinical studies will be needed to identify biomarkers associated with different types of PI in diabetes.

Buying Pattern Discovery Using Spatio-Temporal Data Mart and Visual Analysis (고객군의 지리적 패턴 발견을 위한 데이터마트 구현과 시각적 분석에 관한 연구)

  • Cho, Jae-Hee;Ha, Byung-Kook
    • Journal of Information Technology Services
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    • v.9 no.1
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    • pp.127-139
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    • 2010
  • Due to the development of information technology and business related to geographical location of customer, the need for the storage and analysis of geographical location data is increasing rapidly. Geographical location data have a spatio-temporal nature which is different from typical business data. Therefore, different methods of data storage and analysis are required. This paper proposes a multi-dimensional data model and data visualization to analyze geographical location data efficiently and effectively. Purchase order data of an online farm products brokerage business was used to build prototype datamart. RFM scores are calculated to classify customers and geocoding technology is applied to display information on maps, thereby to enhance data visualization.

Weighted Negative Tree Pattern Discovery (가중치 부여 부정 트리 패턴 추출)

  • Paik, Juryon;Kim, Jinyoung
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2019.07a
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    • pp.23-26
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    • 2019
  • 사물인터넷(IoT)은 지금의 우리가 살고 일하는 모든 방식을 변화시키고 있다. IoT를 통해 데이터를 생성하고 저장하고 연결된 장치와 상호작용하여 비즈니스는 물론 우리의 일상 생활을 개선하고 있는 것이다. 무수히 많은 센서들이 연결된 세상은 센서들에 의해 그 어느 때보다 거대한 양의 데이터들을 생산하고 있다. JSON, XML 같은 트리 구조의 데이터 타입은 대량 데이터 저장 전송 교환 등에 주요하게 사용되는데 이는 트리 구조가 이형 데이터 간의 유연한 정보 전송과 교환을 가능하게 하기 때문이다. 반면에, 효용성 높은 정보나 감추어져 있는 정보들을 트리 구조의 대량 데이터들로부터 추출하는 것은 일반 데이터 구조에 비해 훨씬 어려우며 더 난해한 문제들을 발생시킨다. 본 논문에서는 트리 구조의 대량 스트리밍 데이터로부터 가중치가 부여된 주요한 부정 패턴들을 추출하기 위한 방법을 공식화한다.

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Query Processing based Branch Node Stream for XML Message Broker

  • Ko, Hye-Kyeong
    • International journal of advanced smart convergence
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    • v.10 no.2
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    • pp.64-72
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    • 2021
  • XML message brokers have a lot of importance because XML has become a practical standard for data exchange in many applications. Message brokers covered in this document store many users. This paper is a study of the processing of twig pattern queries in XML documents using branching node streams in XML message broker structures. This work is about query processing in XML documents, especially for query processing with XML twig patterns in the XML message broker structure and proposed a method to reduce query processing time when parsing documents with XML twig patterns by processing information. In this paper, the twig pattern query processing method of documents using the branching node stream removes the twigging value of the branch node that does not include the labeling value of the branch node stream when it receives a twig query from the client. In this paper, the leaf node discovery time can be reduced by reducing the navigation time of nodes in XML documents that are matched to leaf nodes in twig queries for client twig queries. Overall, the overall processing time to respond to queries is reduced, allowing for rapid question-answer processing.

Identification of Potential Prognostic Biomarkers in lung cancer patients based on Pattern Identification of Traditional Korean Medicine Running title: A biomarker based on the Korean pattern identification for lung cancer

  • Ji Hye Kim;Hyun Sub Cheong;Chunhoo Cheon;Sooyeon Kang;Hyun Koo Kim;Hyoung Doo Shin;Seong-Gyu Ko
    • Journal of Society of Preventive Korean Medicine
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    • v.27 no.2
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    • pp.35-48
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    • 2023
  • Objective : We studied prognostic biomarkers discovery for lung cancer based on the pattern identification for the personalized Korean medicine. Methods : Using 30 tissue samples, we performed a whole exome sequencing to examine the genetic differences among three groups. Results : The exome sequencing identified among 23,490 SNPs germline variants, 12 variants showed significant frequency differences between Xu and Stasis groups (P<0.0005). As similar, 18 and 10 variants were identified in analysis for Xu vs. Gentleness group and Stasis vs. Gentleness group, respectively (P<0.001). Our exome sequencing also found 8,792 lung cancer specific variants and among the groups identified 6, 34, and 12 variants which showed significant allele frequency differences in the comparison groups; Xu vs. Stasis, Xu vs. Gentleness group, and Stasis vs. Gentleness group. As a result of PCA analysis, in germline data set, Xu group was divided from other groups. Analysis using somatic variants also showed similar result. And in gene ontology analysis using pattern identification variants, we found genes like as FUT3, MYCBPAP, and ST5 were related to tumorigenicity, and tumor metastasis in comparison between Xu and Stasis. Other significant SNPs for two were responsible for eye morphogenesis and olfactory receptor activity. Classification of somatic pattern identification variants showed close relationship in multicellular organism reproduction, anion-anion antiporter activity, and GTPase regulator activity. Conclusions : Taken together, our study identified 40 variants in 29 genes in association with germline difference of pattern identification groups and 52 variants in 47 genes in somatic cancer tissues.

Discovery of Travel Patterns in Seoul Metropolitan Subway Using Big Data of Smart Card Transaction Systems (스마트카드 빅데이터를 이용한 서울시 지하철 이동패턴 분석)

  • Kim, Kwanho;Oh, Kyuhyup;Lee, Yeong Kyu;Jung, Jae-Yoon
    • The Journal of Society for e-Business Studies
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    • v.18 no.3
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    • pp.211-222
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    • 2013
  • Discovering zones which a1re sets of geographically adjacent regions are essential in sophisticated urban developments and people's movement improvements. While there are some studies that separately focus on movements between particular regions and zone discovery, they show limitations to understand people's movements from a wider viewpoint. Therefore, in this research, we propose a clustering based analysis method that aims at discovering movement patterns, which involves zones and their relations, based on a big data of smart card transaction systems. Moreover, the effectiveness of discovered movement patterns is quantitatively evaluated by using the proposed metrics. By using a real-world dataset obtained in Seoul metropolitan subway networks, we investigate and visualize hidden movement patterns in Seoul.