• Journal of Sasang Constitutional Medicine
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• v.22 no.2
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• pp.135-142
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• 2010

1. Objectives: The purpose of this case is to report that a Tae-eumin patient diagnosed as drug-induced liver injury (DILI) caused by Galgeunhaegi-tang (Gegenjieji-tang) treated with Taeumjowe-tang reduced ephedra to 2g (Taiyintiaowei-tang) and then liver function test Results: improved. 2. Methods: We diagnosed him as Tae-eumin Exterior cold disease induced from the esophagus affected by cold. We made him stop taking Galgeunhaegi-tang (Gegenjieji-tang) and take Taeumjowe-tang reduced ephedra to 2g. (Taiyintiaowei-tang) 3. Results: After our treatment, the symptom and the liver function test Results: improved. 4. Conclusions: The wrong diagnosis of constitution and pathological syndromes can be caused drug-induced liver injury. Taeumjowe-tang reduced ephedra to 2g (Taiyintiaowei-tang) may have an effect on treatment of drug-induced liver injury of Tae- eumin.

• Journal of Sasang Constitutional Medicine
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• v.23 no.1
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• pp.87-97
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• 2011

1. Objectives: We aimed to derive using status of Sasang Constitutional herbal prescription and good effective one in specific disease. 2. Methods: We sent Questionnaire to 463 oriental medical doctor listed Korea Sasang Constitutional medicine from 2009 years. 10 to 11 and got back 191 questionnaire, which consisted of sex, age, clinical duration, working type, using status and effectiveness of Sasang Constitutional herbal prescription. 3. Results: - Digestive tract disease was especially most effective field, and circulatory, the endocrine, dermatology, psychopathy, urogenital disease went in order in western disease. - Spleen disease was especially most effective field, and the heart and circulatory, neuropsychiatry, lung, liver, psychopathy, gynecology disease went in order in oriental medicine pathology. - Chungshimyenja-tang was effective to neuropsychiatry and heart disease in Taeeumin, Hyangsayangwi-tang to disease related digestive system, Palmulgunja-tang to gynecology disease in Soeumin, Dockhalgiwhang-tang to diet disorder, Yanggeuksanwha-tang to heart and psychologic disease in Soyangin. 4. Conclusions: Constitutional prescription effected on special pathological symptom support weaken organ, and these result will help to make treatment standard and support clinical study of constitutional medicine.

• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.37-44
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• 2004

Objectives : The purpose of this report is a study on the correlation between parasympathetic nerve system and Back-shu points. Methods : We have studied about the correlation between anatomical distribution of parasympathetic nerve system and that of Back-shu points. Back-shu points are located on the back area as the acupoints of Bladder Meridian(BL), doing its own organic physical and pathological working and directly connected with its own organ. Results and Conclusions : 1. It is suggested that Back-shu points has correlation with parasympathetic nerve system could be Pangguanshu(BL28), Zhonglushu(BL29), Baihuanshu(BL30), Ciliao(BL32), Zhongliao(BL33), Xialiao(BL34), Shangliao(BL31), Xiaochangshu(BL27), Baohuang,(BL53) Zhibian(BL54) etc. 2. We proved acupuncture treatment on the nearby spinal area could be one of the method that could stimulate parasympathetic nerve system. 3. The symptom of parasympathetic nerve system's disorder is similar to Back-shu points' chief efficacy a lot. And we proved the Back-shu points which has relation with parasympathetic nerve system as distribution of nerve system are only located at sacral area.

• Annals of Clinical Neurophysiology
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• v.7 no.2
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• pp.80-82
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• 2005

Background: Idiopathic Parkinson's disease (IPD) is closely related to Lewy body pathology. Pathological changes in medullar oblongata and pontine tegmentum have been reported in patients with subclinical motor symptom. Vestibular evoked myogenic potential (VEMP) is mediated by vestibular nuclei in lower brainstem and reflects the function of lower brainstem. The purpose of our study is to estimate the lower brainstem function in IPD patients. Methods: Ten patients with idiopathic Parkinson's disease underwent VEMP test. The patients were divided into Hohn-Yahr (H-Y) stage I (unilateral motor involvement) group and H-Y stage II or more severe (bilateral motor involvement) group. VEMP results were compared between groups using Mann-Whitney U test. Results: Among patients, 6 patients showed abnormal VEMP (unilateral abnormality 2, bilateral abnormalities 4). Between H-Y stage I group and H-Y II,III group, there was no statistical difference in the results of VEMP. Conclusions: We concluded that the lower brainstem dysfunction reflected in VEMP could occur in IPD regardless of the progression of the disease.

• Journal of Sasang Constitutional Medicine
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• v.33 no.2
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• pp.25-36
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• 2021

Objectives The aim of this study was to reveal the difference of body shape, personality, physiological characteristics between migrant Vietnam and Daejeon women using propensity matching. Methods The number of 274 Vietnamese migrant women and Daejeon city women participate in this study. We surveyed Sasang Constitution (SC) expressive factor, such Body Mass Index (BMI) using Korea Sasang Constitutional Diagnostic Questionnaire (KS-15). A Chi-square test and a T-test were used. Significant p was .05. Results The height, weight and BMI of Daejeon women was bigger than those of Vietnam(p<.001). There was significant difference in personality characteristics in 'broad mind-narrow mind'(p<.001), 'Active-Passive'(p<.001), 'Masculine-Feminine'(p=.002). There was significant differentce in physio-pathological symptom in 'digestion'(p<.001), 'urine time'(p<.001), 'feeling cold/heat'(p=.006). There was significant differentce in distribution of SC between Vietnam and Daejeon women(p=.025). Conclusions This study reveals that there is differentce in body shape, personality, physiological characteristics between Vietnam and Daejeon women. These factors might influence on SC distribution between Vietnam and Dajeon women

• Physical Therapy Rehabilitation Science
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• v.11 no.3
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• pp.329-334
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• 2022

Objective: Low back pain (LBP) is a symptom that accounts for a large proportion of musculoskeletal pain. Among them, non-specific LBP (NSLBP) means that the pathological cause is unknown, and belongs to the most common LBP. Studies on the mechanism of muscle control in LBP are insufficient, and quantitative studies are needed. Design: Observational cross-sectional study design Methods: A Thirty participants with NSLBP symptoms were enrolled, and their pressure pain thresholds (PPT) and muscle and fat thickness were measured. Participants measured the paraspinal muscles (PM) of the thoracic and lumbar spine and medial hamstring (semitendinosus) on the dominant and non-dominant sides in the prone position. Results: Among the variables that were significant in the correlation analysis, PM of the thoracic and lumbar spine showed a significant relationship in the PPT ([thoracic spine PM]=1.141+0.912 [lumbar spine PM]). Also, there was a significant relationship between the lumbar spine PM in the PPT and the thoracic spine PM in the muscle thickness ([lumbar spine PM of PPT]=4.057+0.117 [thoracic spine PM of muscle thickness]) Conclusions: Although there was no muscle imbalance according to the dominant and non-dominant side, there is a correlation between the pressure pain threshold and the muscle thickness between the paraspinal muscles of the thoracic spine and the lumbar spine.

• Journal of Digestive Cancer Research
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• v.2 no.2
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• pp.82-84
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• 2014

We report a case with dysphagia for solids. A 51-year-old man with benign esophageal stricture was transferred for endoscopic treatment. He had lye ingestion history at 9 years old and underwent esophagectomy with right colonic interposition for the treatment of the benign esophageal stricture. But his symptom was acting up 2 years ago and lasted afterward even though he had underwent endoscopic treatments for dysphagia several times, including balloon dilation and stent insertion. He had polypoid enhancing wall thickening around anastomosis site of stomach with perigastric soft tissue density and suspicious nodular extension to omentum on the small bowel computed tomography. So he had a surgical resection of small bowel and jejunojejunostomy, and the pathological result was adenocarcinoma, intestinal type with soft tissue infiltration. Later he underwent total gastrectomy with segmental resection of interpositional colon and segmental resection of duodenum and ileo-colic anastomosis revision. And recently he has been on chemotherapy.

• Sleep Medicine and Psychophysiology
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• v.3 no.2
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• pp.1-17
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• 1996

To demonstrate the clinical usefulness of electroencephalography (EEG) and factors increasing the usefulness of EEG, the authors evaluated each relationship between EEG related factors and clinical variables, and neuroimaging studies (CT and MRI)-related factors, and factors which are related with routine neurological examination for 207 patients who had been evaluated with both of EEG and neuroimaging study(CT or/and MRI). The results were as follows: 1) Abnormality of EEG findings had significant relationships with chief complaints, diagnosis, medication use, seizure attack, pathological reflex, and level of consciousness. However there were no significant correlations between abnormality of EEG findings and neuroimaging studies (CT and MRI)- related factors. 2) Laterality of EEG findings had significant relationships with abnormality, laterality, and focality of CT findings, and also with abnormality of MRI findings. But there were no significant correlations between laterality of EEG findings and clinical variables, and neurological examination-related factors. 3) Anterior-posterior distribution of EEG findings was significantly related with medication use. 4) Focality of EEG findings had significant relationships with sex, sensory dysfunction sign, and cerebellar dysfunction sign. But there were no significant correlations between focality of EEG findings and neuroimaging studies(CT and MRI) related factors. 5) Abnormal EEG pattern had significant correlations with various factors, such as age, chief complaints, duration from onset of symptom to taking MRI, seizure attack, abnormality and nature of lesion in CT findings, cortical atrophy in MRI findings, motor dysfunction sign, sensory dysfunction sign, and pathological reflex. 6) With abnormality on sleep activation, age, age of onset, seizure attack, ventricular enlargement in CT findings, and abnormality of MRI findings were significantly correlated. 7) With abnormality on hyperventilation activation, duration of illness and laterality of MRI findings were significantly correlated. Above results may suggest that abnormality of EEG findings is more closely related with functional change of the brain than structural changes of the brain and laterality of EEG findings is vice versa. And also that medication use has an influence on anterior versus posterior distribution of EEG findings and focality of EEG findings is not related with structural changes of the brain. Activation with sleep may be effective to show age differences and provocation of seizure activity and hyperventilation may be effective to detect the abnormal EEG findings by cerebrovascular insufficiency.

• Korean Journal of Head & Neck Oncology
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• v.15 no.1
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• pp.70-75
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• 1999

Objectives: This study was designed to evaluate the methods of diagnosis and treatment of thyroid nodules. Materials and Methods : We performed a clinical review of patients with thyroid nodules, who were surgically treated at the Department of Surgery, College of Medicine, Chosun University from January 1996 to December 1998. Results: 1) The patients were divided into two groups; 65 patients(80.2%) with benign nodular disease and 16 patients(19.8%) with malignant disease. 2) The sex distribution showed a preponderance of females with a ratio of 5.2:1 in benign nodular disease and 3:1 in malignant disease. Benign nodules were more prevalent in patients in their 40's as compared to malignant nodules in patients in their 50's and 60's. 3) The most common duration of illness was 3 months, occurring in 45.7% of the total cases. 4) The most prominent symptom and sign was a palpable nodule in the anterior aspect of the neck. 5) The location of the nodule was ; 41 cases in the right lobe, 29 cases in the left lobe, and 11 cases in both lobes. 6) Thyroid scanning of 40 patients revealed cold nodules in 90.6% of benign nodules and in all malignant disease. 7) Fine needle aspiration cytology were performed in 32 cases of the 81 patients. Comparing with postoperative pathological findings, the results were the same in 87.5% of 32 cases. 8) Intra-operative frozen section study was performed in 56 cases of the 81 patients. Comparing with postoperative pathological finding, the results were same in 96.4% of the 56 cases. 9) The histopathological classification revealed that adenomatous goiters were the most common benign disease and papillary carcinomas were the most common malignant disease. 10) The most frequently employed operation for benign nodules and malignant disease was unilateral total lobectomy. When the metastasis was confirmed, lymphadenectomy and radical neck dissection was performed in malignant disease. 11) Important postoperative complications were transient hoarseness, transient hypocalcemia, hypothyroidism, wound bleeding, and hoarseness. Conclusions: The results of this study suggest that palpable nodules in anterior aspect of neck is revealed cold nodule by thyroid scanning and malignancy by fine needle aspiration cytology, which should be removed surgically. There is no difference in complication and survival rate with type of operation and lymphatic dissection. Therefore, procedure of operation is dependent on the site of nodule and involvement of lymph node.

• Journal of Korean Medical classics
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• v.21 no.3
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• pp.1-25
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• 2008

Myeong(明) Dynasty Period put together clinically various medical theory in Song(宋) Dynasty and Geum-Won(金元) age, organized medical system. They have been developed in theory, which thought of Byeonjeungronchi(辨證論治) more important, and clinical part which included diagnosis, therapy, prevention. In that age reactional medical thought was in fashion because of affect of Ihak(理學), therefore pediatrics have been affected from them. Especially, looking at the symptom of Byeonjeungronchi doctors, Manjeon(萬全), Nobaeksa(魯伯嗣), Wangdaeryun(王大綸), Wanggeungdang(王肯堂), Nuyeong(樓英) had succeed to Jeoneul(錢乙)' the five viscera Byeonjeung(辨證) system. Manjeon advocated Samyuyeosabujokron(三有餘四不足論) about Jangbu(臟腑) and organized the curative principle about Ojangheosil(五臟虛實). Gupyeong(寇平), commented on diagnosis of five viscera and classification of disease of five viscera. Wangdaeryun in the close of Myeong Dynasty Age explained main pulse, pulse of illness in detail according to weakness or strength of five viscera, pathological or physiological features of five viscera and Saenggeuk(生克) relation of Ohaeng(五行) in the book of "Yeongdongryuchwe(嬰童類萃)". Wanggeungdang and Nuyeong had organized system of argument which classified disease as a result of symptom of five viscera. "Yugwajeungchijunseung(幼科證治準繩)" and "Uihakgangmok(醫學綱目) Soabu(小兒部)" had been written by this principle. Nobaeksa had arranged the principle of cure about five viscera and explained method of common use about each organ's disease. Besides, Seolgi(薛己), Janggyeong-ak(張景岳), insisted about Myeongmun(命門) because he thought of Bisin(脾腎) of children and vigor by nature importance. Seolgi had applied and used very well Bojung-ikgitang(補中益氣湯) based on Idongwon(李東垣)'s Biwiseol(脾胃說) and controled and helped spleen and stomach. At the same time, he took a serious view about supplementing children's Sin-gi(腎氣) according to so many spleen and stomach disease was fallen because they couldn't make warm the spirit of Jungju(中州), result of weakening Hwa(火) of Myeongmun. Also Janggyeong-ak took a serious view strengthen of Bisin, so he assorted and used Insam(人蔘) and Buja(附子) to supplement children's weaken energy in kidney Jeonggi(精氣).