• Clinical and Experimental Reproductive Medicine
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• v.47 no.2
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• pp.122-129
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• 2020

Objective: The survival of a semi-allogeneic fetus depends on several immunological mechanisms, and it has been suggested that recurrent pregnancy loss (RPL) could develop as a result of one or more immunological abnormalities. Methods: Compatibility between partners for human leukocyte antigen (HLA) genotypes and the relationships between maternal killer-cell immunoglobulin-like receptor (KIR) and paternal HLA-Bw4/Bw6 and HLA-C1/C2 supra-groups were investigated in 25 couples with RPL in comparison to healthy couples with children. HLA and KIR genotyping was performed using polymerase chain reaction with sequence-specific primers and/or sequence-specific oligonucleotides. Results: HLA class I incompatibility between partners, especially in HLA-B alleles, was more common in the RPL group (p= 0.01). HLA-C2 homozygosity was more frequent in the male partners of RPL couples than in other groups (p= 0.03). The KIR2DL5 gene frequency was significantly higher in both the female and male partners of RPL couples, whereas the KIR2DS3 gene frequency in male partners of RPL couples was significantly reduced (p= 0.03). The presence of KIR2DL3 in women with RPL was correlated with the presence of HLA-C2 alleles in their spouses (p= 0.03). Conclusion: Our data from a Turkish population suggest that male HLA-C2 homozygosity may play an important role in RPL. Additionally, an incidental match between male HLA-C2 and female HLA-C1 ligand KIR receptors might perturb the balance between activatory and inhibitory KIR-ligand interactions during pregnancy in couples affected by RPL. The roles of orphan KIR2DL5 and orphan KIR2DS3 in RPL remain obscure.

• The Journal of the Korea Contents Association
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• v.13 no.9
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• pp.260-269
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• 2013

Gender role identity is a key subject toward adaptation in later life. In this paper, we tried to understand the specific types and characteristics of gender role identity in view of older men. The research collected and examined 40 representative descriptions representing gender role identity, including 20 for masculinity and 20 for femininity from 40 older men. We obtained four types of gender role identity of older men from this research. "Powerful-expressive type" is energetic and reveals his brave and dominant tendency when they are working. "Powerful-taciturn type" is strongly independent and has a firm conviction, but they do not express those characters and remain silent. "Powerful-paternal type" handles his work with a driving force, and has a tender character. "Paternal-caring type" finds his own worth in life by caring for his family and children, and considers others more than himself. Future research is needed to verify how the types of gender role identity are linked to psychosocial adaptive aspects, health behaviors, mental and physical health.

• Journal of Genetic Medicine
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• v.14 no.1
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• pp.18-22
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• 2017

Pseudohypoparathyroidism type 1b (PHP 1b) is the result of end organ resistance to parathyroid hormone (PTH) in the absence of any features of Albright's hereditary osteodystrophy. There are two subtypes of PHP 1b with different genetic mechanisms. One subtype is related to a maternally derived 3kb microdeletion involving STX 16 gene, and is inherited in an autosomal dominant mode. Familial autosomal dominant inheritance of PHP 1b is relatively rare. The other subtype is associated with more extensive loss of imprinting at the GNAS locus that affects at least one additional differential methylated (hypermethylation at neuroendocrine secretory protein and hypomethylation at antisense transcript and or extra-large stimulatory G protein region) without microdeletion of the STX 16 or AS gene. It can be sporadic due to an imprinting defect in the GNAS gene. In our case, an 8-year-old girl was referred for suspected PHP with no feature of Albright hereditary osteodystrophy. Blood test results revealed hypocalcemia and hyperphosphatemia. Elevated PTH was also checked. There was no family history of endocrine or developmental problem. Her intelligence was normal, but she had inferior sociability at that time. Based on above, we diagnosed a rare case of paternal uniparental disomy of the long arm of chromosome 20 as the cause of PHP 1b by microsatellite marker test of chromosome 20.

• Women's Health Nursing
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• v.26 no.2
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• pp.161-170
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• 2020

Purpose: This study was conducted to identify the influences of the attitudes of pregnant women and their husbands towards sex during pregnancy on sexual function. Additional purpose was to compare the frequency of sexual dysfunction according to gender and gestational trimester and to describe the changes in sexual behavior according to the gestational trimester. Methods: In this study, 231 pregnant couples completed self-report questionnaires during their visits to women's hospitals or community health centers. The questionnaires assessed general characteristics, maternal/paternal sexual attitudes towards sex during pregnancy (Maternal Sex during Pregnancy Scale, MSP/Paternal Sex during Pregnancy Scale, PSP), and sexual function (using the Female Sexual Function Index and International Index of Erectile Function, respectively). Multiple regression analysis was done to test the research model using SPSS version 23.0. Results: In this study, 74.9% of pregnant women and 38.5% of their husbands reported sexual dysfunction. Sexual dysfunction was prevalent in pregnant women in the first trimester and prevalent in husbands in the third trimester. MSP (β=.44, p<.001) in pregnant women and PSP (β=.39, p<.001) and being in the first trimester (β=.17, p=.012) in husbands influenced sexual function during pregnancy. In the first trimester, the scores for attitudes towards sex during pregnancy were the lowest in pregnant women, while they were the highest in their husbands. Conclusion: Positive attitudes about sex during pregnancy are important for sexual function in pregnant couples. Because the difference in attitudes towards sex during pregnancy between pregnant women and their husbands was greatest in the first trimester, sexual health interventions need to be provided in early pregnancy.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.20 no.2
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• pp.44-49
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• 2020

Pseudohypoparathyroidism (PHP) is a disorder characterized by hypocalcemia and hyperphosphatemia due to end organ resistance to parathyroid hormone. PHP is caused by the deficiency of the α-subunit of the stimulatory G protein encoded by the GNAS gene, and this defect arises from genetic or imprinting disturbances. Sporadic PHP 1b shows two or more methylation defects of upstream of GNAS gene and some of them lead to loss of maternal GNAS imprints, therefore, only paternally derived GNAS gene is expressed. Here, we report a 10 year 9 month old boy presented with intermittent tetany who was finally diagnosed with PHP 1b caused by paternal uniparental disomy of chromosome 20q.

• Human Ecology Research
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• v.61 no.3
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• pp.319-333
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• 2023

The purpose of this study was to examine which sibling and parent-child characteristics were associated with siblisng warmth and conflict among Korean young adults. The data came from an online survey of Koreans aged 19-34 years who had at least one sibling and two living parents. We conducted a multilevel regression analysis using data from 193 men with 305 siblings and 203 women with 286 siblings. The results showed that, for men, the levels of warmth were higher when the sibling was younger, when they received more frequent financial and instrumental support from the sibling, and when maternal favoritism was relatively lower. Women reported higher levels of warmth when the sibling was a sister, when they provided more frequent support for the sibling, when they had a more affectionate relationship with the mother, and when paternal favoritism was lower. As for sibling conflict, the number of siblings was positively associated with the levels of conflict among both men and women. Maternal affection was negatively related with conflict for men, and paternal favoritism was positively related to conflict for women. Interestingly, women's sibling warmth and conflict were both higher when the sibling was a sister, which meant that relationships between sisters tended to be ambivalent. This study contributes to our understandings of Koreans' sibling relationships in young adulthood.

• Horticultural Science & Technology
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• v.31 no.6
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• pp.790-797
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• 2013

During pear fruit development, calyx can abscise from fruitlet following petal fall. The calyx abscission varies with pear cultivars. The presence of calyx on pear fruit makes the fruit shape calyx end protruded. In the present study, the degrees of the calyx abscission were examined in 120 Southern-type Asian pear (Pyrus pyrifolia), 52 Nothern-type Asian pear (P. ussuriensis), and 34 European pear (P. communis) cultivars, and its inheritance was investigated using cross combinations between the Southern-type Asian pear cultivars showing different degrees of calyx abscission. Majority of the cultivars produced < 10% or > 90% calyx-perpetual fruit, but the cultivars producing both calyx-perpetual and -deciduous fruit were in minor frequency. The cultivars producing < 10% calyx-perpetual fruit were in higher frequency in Southern-type Asian, Nothern-type Asian, and European pears in that order, while those producing calyx-perpetual fruit were in higher frequency in European, Nothern-type Asian, and Southern-type Asian pears in that order. In the cross between the parents producing < 10% calyx-perpetual fruit, most of the $F_1$ seedlings also produced < 10% calyx-perpetual fruit. In the cross between the parents producing > 90% calyx-perpetual fruit, on the contrary, most of the $F_1$ seedlings also produced > 90% calyx-perpetual fruit. When the paternal parent produced < 10% calyx-perpetual fruit, most of the $F_1$ seedlings also produced < 10% calyx-perpetual fruit regardless of the degree of calyx abscission in the maternal parent. When the cross was between the maternal parent producing < 10% calyx-perpetual fruit and the paternal parent showing different degrees of calyx abscission, the $F_1$ seedlings showed similar degrees of the calyx abscission to those in the paternal parent. These results suggest that the characteristics of the calyx abscission is influenced more greatly by the paternal parent than by the maternal parent, and the calyx abscission in Southern-type Asian pears is a qualitative trait which is governed by dominant gene(s).

• Journal of the Korean Home Economics Association
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• v.48 no.9
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• pp.103-111
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• 2010

The purpose of this study was to investigate the effects of perceived parental acceptance on social anxiety and depressive symptoms in children. Seven hundred and thirty eight 5th and 6th graders completed questionnaires. Regression analyses indicated that low levels of paternal acceptance was associated with higher social anxiety and depressive symptoms. Gender was a moderator of the effects of maternal acceptance on social anxiety and depressive symptoms. With high levels of maternal acceptance, girls were significantly less likely to report social anxiety and depressive symptoms, compared to boys. These results highlight the important role of parental acceptance in manifestations of social anxiety and depressive symptoms and clarify the relation of maternal acceptance to social anxiety and depressive symptoms as a function of gender.

• Journal of Families and Better Life
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• v.23 no.5 s.77
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• pp.93-102
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• 2005

The present study examined how demographic, paternal, and children's variables were associated with role satisfaction of Korean fathers with young children. Subjects were 236 fathers of 3-5 year old children living in Jeju island in Korea. Data were collected using questionnaires. Among demographic variables, father's income is an only variable that effects on role satisfaction. Role satisfaction is positively associated with child care, marital, job satisfaction, and child-rearing participation in terms of psychological variables. According to multiple regression, role satisfaction was positively predicted by income, gender, and adaptability of children. Moreover, day care, marital, job satisfaction and child-rearing participation were significant predictors of role satisfaction.

• Journal of Families and Better Life
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• v.15 no.1
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• pp.225-237
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• 1997

The Purpose of this study was to examine how children's perceptuions of parental childrearing behaviors and family support were related to their interpersonal problem-solving behaviors. 580 subjects of the 5th 6th grades filled out questionnaires concerning the three research variables. The data were analyzed through correlation analyses and regression analyses. The results were as follows: The significant correlations were found between parental warmth·acceptance and children's interpersonal problem-solving behavior and between family support and problem-solving behaviors. Problem-solving behaviors showed higher correlations with maternal warmths·acceptance than paternal behaviors and with opposite-sex parents behaviors than with same-sex parents behaviors. Family support predicted children's social problem-solving behaviors better than parental warmth·acceptance especially among boys.