• 제목/요약/키워드: passive smoking

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Distribution of maternal risk factors for orofacial cleft in infants in Indonesia: a multicenter prospective study

  • Andi Tajrin;M. Ruslin;Muh. Irfan Rasul;Nurwahida;Hadira;Husni Mubarak;Katharina Oginawati;Nurul Fahimah;Ikeu Tanziha;Annisa Dwi Damayanti;Utriweni Mukhaiyar;Asri Arumsari;Ida Ayu Astuti;Farah Asnely Putri;Shinta Silvia
    • 대한두개안면성형외과학회지
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    • 제25권1호
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    • pp.11-16
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    • 2024
  • Background: The pathogenesis of orofacial cleft (OFC) is multifactorial, involving both genetic and non-genetic factors, the latter of which play a key role in the development of these anomalies. This paper addresses the incidence of OFC in Indonesia, with a focus on identifying and examining the distribution of contributory factors, including parental medical history, pregnancy history, and environmental influences. Methods: The study was conducted through the collection of primary data. An interdisciplinary research team from Indonesia administered a standardized questionnaire to parents who had children with OFC and who had provided informed consent. The case group comprised 133 children born with cleft lip and/or palate, and the control was 133 noncleft children born full-term. The risk factors associated with OFC anomalies were analyzed using the chi-square test and logistic regression. All statistical analyses were performed using SPSS version 25. A p-value of 0.05 or less was considered to indicate statistical significance. Results: The study comprised 138 children, of whom 82 were boys (59.4%) and 56 were girls (40.6%). Among them, 45 patients (32.6%) presented with both cleft lip and cleft palate, 25 individuals (18.1%) had a cleft palate only, and 28 patients (20.3%) had a cleft lip only. OFC was found to be significantly associated with a maternal family history of congenital birth defects (p<0.05), complications during the first trimester (p<0.05), consumption of local fish (p<0.05), caffeine intake (p<0.05), prolonged medication use (p<0.05), immunization history (p<0.05), passive smoking (p<0.05), and X-ray exposure during pregnancy (p<0.05). Conclusion: The findings indicate close relationships between the incidence of OFC and maternal medical history, prenatal factors, and environmental influences.

Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)

  • Shin, Youn Ho;Yu, Jinho;Kim, Kyung Won;Ahn, Kangmo;Hong, Seo-Ah;Lee, Eun;Yang, Song-I;Jung, Young-Ho;Kim, Hyung Young;Seo, Ju-Hee;Kwon, Ji-Won;Kim, Byoung-Ju;Kim, Hyo-Bin;Shim, Jung Yeon;Kim, Woo Kyung;Song, Dae Jin;Lee, So-Yeon;Lee, Soo Young;Jang, Gwang Cheon;Suh, Dong In;Yang, Hyeon-Jong;Kim, Bong Sung;Hong, Soo-Jong
    • Clinical and Experimental Pediatrics
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    • 제56권10호
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    • pp.439-445
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    • 2013
  • Purpose: Previous studies suggest that the concentration of 25-hydroxyvitamin D [25(OH)D] in cord blood may show an inverse association with respiratory tract infections (RTI) during childhood. The aim of the present study was to examine the influence of 25(OH)D concentrations in cord blood on infant RTI in a Korean birth cohort. Methods: The levels of 25(OH)D in cord blood obtained from 525 Korean newborns in the prospective COhort for Childhood Origin of Asthma and allergic diseases were examined. The primary outcome variable of interest was the prevalence of RTI at 6-month follow-up, as diagnosed by pediatricians and pediatric allergy and pulmonology specialists. RTI included acute nasopharyngitis, rhinosinusitis, otitis media, croup, tracheobronchitis, bronchiolitis, and pneumonia. Results: The median concentration of 25(OH)D in cord blood was 32.0 nmol/L (interquartile range, 21.4 to 53.2). One hundred and eighty neonates (34.3%) showed 25(OH)D concentrations less than 25.0 nmol/L, 292 (55.6%) showed 25(OH)D concentrations of 25.0-74.9 nmol/L, and 53 (10.1%) showed concentrations of ${\geq}75.0$ nmol/L. Adjusting for the season of birth, multivitamin intake during pregnancy, and exposure to passive smoking during pregnancy, 25(OH)D concentrations showed an inverse association with the risk of acquiring acute nasopharyngitis by 6 months of age (P for trend=0.0004). Conclusion: The results show that 89.9% of healthy newborns in Korea are born with vitamin D insufficiency or deficiency (55.6% and 34.3%, respectively). Cord blood vitamin D insufficiency or deficiency in healthy neonates is associated with an increased risk of acute nasopharyngitis by 6 months of age. More time spent outdoors and more intensified vitamin D supplementation for pregnant women may be needed to prevent the onset of acute nasopharyngitis in infants.

암환자 인식에 관한 연구 - 간호사ㆍ의사를 중심으로

  • 조인향
    • 호스피스학술지
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    • 제2권1호
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    • pp.58-74
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    • 2002
  • This paper constitutes a descriptive investigation and used a structured questionnaire to investigate nurses' and doctors' recognition of cancer patients. The subjects were extracted from the medical personnel working at the internal medicine, the surgery ward, the obstetrics and gynecology department, the pediatrics department, the cancer ward, and the emergency room of five general hospitals located in Seoul and Gyeonggi Province. The research lasted from August, 2001 to September 2001. Total 137 nurses and 65 doctors were included and made out the questionnaires directly distributed by the investigator. The study tool was also developed by the investigator and consisted of such items as the demographic and social characteristics, the medical personnel's recognition degree of cancer and cancer patients, their recognition of the management of cancer patients, and their participation in a hospice. The results were analyzed using the SPSS Window program in terms of technological statistics, ranks, t-test, and ANOVA. The reliability was represented in Cronbach' α=.75. The nurses' and doctors' recognition degree of cancer and cancer patients had an overall average of 3.86 at the 5 point-scale. The items that received an average of 4.0 or more included 'Medical personnel should explain about the cancer cure plans to the cancer patient and his or her family', 'A patient whose case has been diagnosed as a terminal cancer should be notified of it, 'If I were a cancer patient, I would want to get informed of it,' and 'Cancer shall be conquered whenever it is'. In the meantime, the items that received an average of 3.0 or less was 'My relationship with the cancer patient's family has gotten worse since I announced his or her impending death.' And according to the general characteristics and the difference test, the recognition degree of cancer and cancer patient was high among the subgroups of nurses, females, married persons, who were in their 30s, who had a family member that was a cancer patient, and who received a hospice education. The biggest number of the nurses and doctors saw 'a gradual approach over several days'(68.8%) as a method to tell a cancer patient about his or her cancer diagnosis or impending death. Those who usually tell tragic news were the physician in charge(62.8%), the family members or relatives(32.1%) and the clergymen(3.8%) in the order. The greatest number of them recommended a cancer patient's home as the place where he or she should face death because they thought 'it would stabilize his or her mentality'(91.9%) while a number of them recommended the hospital because they 'should give the psychological satisfaction to the patient'(40%) or 'should try their best until the last moment of the patient's death'(30%). A majority of the medical personnel regarded 'smoking or drinking' and 'diet' as the causes of cancer. The biggest symptom of a cancer patient was 'pain' and the pain management of a cancer patient was mostly impeded by the 'excessive fear of drug addiction, tolerance to drugs and side effects of drugs' by medical personnel, the patient, and his or her family. The most frequently adopted treatment plan of a terminal cancer patient was 'to do whatever the patient or his or her family wants' to resort to a hospice' and 'to continue active treatment efforts' in the order. The biggest reasons why a terminal cancer patient went to see a doctor were 'pain alleviation' 'control of symptoms other than pain(intravenous supply)' and 'incapability of the patient's family' in the order. Terminal cancer patients placed their major concern in 'spiritual(religious) matter' 'emotional matters' their family' 'existence' and 'physical matters' in the order. 113(58.5%) of the whole medical personnel answered they 'would recommend' an alternative treatment to a terminal cancer patient mostly because they assumed it would 'stabilize the patient's mentality.' Meanwhile, 80(41.5%) of them chose 'not to recommend it mostly due to the unverified effects and high cost of it(78.7%). A majority of them, I. e. 190(94.1%) subjects said they 'would recommend' a hospice to a terminal cancer patient mostly because they thought it would help the patient to 'mentally prepare'(66.6%) Only 17.3% of them, however, had received a hospice education, most of which was done through the hospital duty education(41.4%) and volunteer training(34.5%). The follows are results of this study: 1. The nurses and the doctors turned out to be still passive and experience confusion in dealing with a cancer patient despite their great sense of responsibility for him or her. 2.Nurses and Doctors realize the need of a hospice, but an extremely small number of them participate in a hospice education or performance. Thus, a whole recognition of a hospice should be changed, for which purpose a hospice education for nurses and doctors should be provided. 3.Terminal cancer patients preferred their home to a hospital as the place to face their impending death because they felt it would bring 'mental stability.' And most of nurses and doctors think it would be unnecessary for them to be hospitalized just for control of their symptoms. Accordingly a terminal cancer patient can be cared at home, and a home hospice care needs to be activated.

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대학생의 라이프스타일 유형에 따른 신체계측, 식행동, 건강관련 생활습관 및 영양소 섭취상태에 관한 연구 (Anthropometric Measurement, Dietary Behaviors, Health-related Behaviors and Nutrient Intake According to Lifestyles of College Students)

  • 정선희;나영주;이은희;장경자
    • 한국식품영양과학회지
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    • 제36권12호
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    • pp.1560-1570
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    • 2007
  • 본 연구는 2003년에 행해진 연구이나 일반적으로 라이프스타일은 미시적 차원인 특정개인으로부터 거시적 차원인 사회전체에 이르기까지 여러 규모의 차원으로 파악되고 있으며 이는 개인의 전반적인 활동이나 인식에 영향을 주는 생활양식의 개념으로 여겨지는 점과 다른 선행연구들을 살펴볼 때 일반적으로 10년을 주기로 라이프스타일에 따른 변화를 살펴본 연구들이 많은 점으로 미루어 볼 때 본 연구 결과가 현재의 라이프스타일을 반영할 수 있는 것으로 사료된다. 본 연구에서는 전국 남녀 대학생의 라이프스타일에 따른 신체계측, 식행동, 건강관련 생활습관 및 영양섭취실태를 비교하고자 설문조사를 실시하였으며 조사결과는 다음과 같다. 조사대상자의 연령은 남학생 평균 23.7세, 여학생 평균 21.6세였다. 남학생의 경우, 체중은 '개방적 유행추구형'군이 64.1 kg으로 다른 군에 비해 유의적으로 낮은 것으로 조사되었으며, 여학생의 경우, 신장과 체중은 '성취적 가족추구형'군이 평균 160.9 cm, 50.7 kg으로 '소극적절약 외모지향형'군의 평균 162.7 cm, 52.7 kg과 '개방적 유행추구형'군의 평균 163.1 cm, 53.0 kg에 비해 유의적으로 낮은 것으로 조사되었다. 균형 잡힌 식사 여부에 관한 질문에서 "항상 균형 잡힌 식사를 한다"고 응답한 비율은 '적극적 건강추구형'군이 23.3%로 다른 군에 비해 유의적으로 높은 응답율을 보였다. 신용카드로부터 식비 지출금액의 경우 '개방적 유행추구형'군이 월 평균 23.7만원을 사용한데 비해 '비소비 대인관계추구형'군은 월평균 8.5만원을 식비로 지출한다고 응답하여 유의적인 차이를 보였다. 건강관련 생활습관과 관련하여 '적극적 건강추구형'군이 다른 군에 비해 운동량은 많은 반면 음주와 흡연은 적게 하는 것으로 조사되었다. 결식의 경우 '소극적절약 외모지향형'군이 유의적으로 가장 적은 결식율을 보였으나 라이프스타일 유형과 상관없이 모든 대학생들의 하루 중 3끼 이상 결식하는 경우가 80% 이상으로 나타나 대학생들의 올바른 식습관 형성을 위한 영양교육이 필요한 것으로 사료된다. 체중조절을 하는 이유로는 '비소비 대인관계추구형'의 16.2%가 "건강을 위해서"라고 응답한 반면 '소극적절약 외모지향형'과 '개방적 유행추구형'의 24.8%와 26.3%가 "외모를 위해서"라고 응답하여 유의적인 차이를 보였으나 체중조절 방법으로는 대부분이 "약물복용", "운동요법", "비만클리닉" 등의 순인 것으로 조사되었다. 라이프스타일 유형에 따른 영양소 섭취상태는 남학생의 경우 '개방적 유행추구형'군이 '적극적 건강추구형'과 '성취적 가족추구형'군에 비해 유의적으로 높은 비타민 C의 섭취량을 보였으며 여학생의 경우 '적극적 건강추구형'군이 '성취적 가족추구형'군에 비해 유의적으로 낮은 비타민 $B_2$, 칼슘 및 철분 섭취량을 보였다. 그러나 전반적으로 볼 때 라이프스타일에 관계없이 남녀 대학생 모두 에너지와 칼슘 섭취량이 한국인 영양섭취기준의 70% 수준으로 나타났으며 특히 여학생의 경우 철분의 섭취량이 한국인 영양섭취기준의 80% 수준으로 매우 낮은 섭취율을 보였다. 이상의 결과로 볼 때 경제발전과 사회구조의 변화에 따라 대학생들의 식행동, 건강관련 생활습관 및 영양소 섭취실태도 라이프스타일에 따라 다르게 나타나는 것을 볼 수 있다. 그러므로 대학생 시기의 올바른 라이프스타일의 확립 및 영양밀도가 높은 식품섭취를 통해 건강한 생활을 영위할 수 있도록 학교나 지역사회 및 정부차원에서의 지속적이고 체계적인 영양교육이 필요하다. 또한 일단 성립된 바람직하지 않은 라이프스타일은 쉽게 변화하지 않으므로 이론 위주의 영양교육보다는 실제적인 행동변화를 유도할 수 있는 적극적인 영양교육 프로그램의 개발이 필요한 것으로 사료된다.