• 아동학회지
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• 제23권2호
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• pp.31-47
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• 2002

In this study, the perceptions and responses of 136 kindergarten children from middle SES families were recorded in one-to-one interviews about the cause, reasons for expression, and responses to negative emotions. Results showed that children perceived he causes of anger and sadness as 'interpersonal events' and they perceived he cause of fear to be 'fantasy/scary events'. The children tended not to express their negative emotions because they expected negative responses from their peers and mothers, but when they did, the expressed their negative emotions to their mothers rather than to peers. Children responded to the negative emotions of their peers with 'problem-solving focused strategies', but they responded to their mothers' negative emotions with passive strategies, such as 'emotion focused response' and 'avoidance'.

• 대한간호학회지
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• 제38권4호
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• pp.522-532
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• 2008

Purpose: The purpose of this study was to identify the types of anger expression in adolescent women. Methods: The Q-Methodology which provides a method of analyzing the individual's subjectivity was used. The 32 subjects classified 50 selected Q-statements on a 9 point scale to make a normal distribution. The collected data was analyzed by a PC-QUANL program. Results: Five types of anger expression in adolescent women were identified. Type I: Direct attacking expression type, Type II: Mature consideration type, Type III: Passive indirect expression type, Type IV: Avoidance conversion type, and Type V: Expression control type. Conclusion: This study revealed that different approaches of nursing intervention strategies are recommended based on the five types of anger expression and their characteristics.

• 대한의생명과학회지
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• 제23권3호
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• pp.281-285
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• 2017

The purpose of the current study is to investigate the cognition-enhancing effects of Ixeris dentata (Thunb) Nakai in scopolamine-induced amnesic mice. Scopolamine (2 mg/kg, i.p.) was used to induce amnesia in mice. The cognitive-enhancing activity of the IDE (10, 20 and $40{\mu}g/mL$) was studied by passive avoidance response, elevated plus maze and Y-maze behavioral paradigm in normal and scopolamine-induced amnesic mice. Scopolamine-induced cognitive deficits were significantly reversed by IDE (P < 0.001 at 20 mg/kg) in a dose-dependent fashion in all the behavioral paradigms tested. IDE possesses cognitive-enhancing properties in amnesic mice due to its potent antioxidant action.

• Journal of Microbiology and Biotechnology
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• 제23권12호
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• pp.1779-1784
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• 2013

Although enzyme-hydrolyzed silk fibroin has been reported to enhance cognitive function before, it has been still unknown which peptides can improve memory. Here we report that amino acid sequences of three novel peptides were identified from fibroin hydrolysate. Fibroin hydrolysate was obtained by hydrolysis with protease after partial hydrolysis with 5M $CaCl_2$. Synthesized peptides derived from these sequences improved scopolamine-induced memory impairments in mice. We confirmed this hydrolysate had effects that improved learning and memory abilities by performing the Rey-Kim test. From this hydrolysate of silk fibroin, amino acid sequences of eight peptides were identified by LC-MS/MS. Three peptides (GAGAGTGSSGFGPY, GAGAGSGAGSGAGAGSGAGAGY, and SGAGSGAGAGSGAGAGSGA) were synthesized to investigate whether they could improve memory. Passive avoidance test and Morris water maze test were performed, and all peptides showed memory-enhancing abilities on scopolamine-induced memory impairments in mice. In this study, we identified three novel peptides that could improve memory, and that silk fibroin hydrolysate was a mixture of various active peptides that could enhance memory.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.389-389
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• 2000

The number of automobiles is rapidly increasing , as are the importance of the car as a way of transportation, and the variety of its uses. In these surroundings, a safety, one of the primary factors which must be considered in automotive engineering, demands a system that aids the driver's vision and perception. In this point of view, development of the more promoted system that complement the existing passive method which relies on just man's ability is the important issue of the advanced traffic system including ITS. In this paper, we provide an algorithm and implementation of a control system that warns the collisions ahead and avoids this situation, using informations about the host-car, target-car and surroundings. The warning is made by an algorithm that decides the degree of safely. With this degree of safely, the controller automatically controls a vehicle's speed to a proper level.

• 생약학회지
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• 제39권2호
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• pp.86-90
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• 2008

Two decursin derivatives were synthesized from decursinol. Compounds 1 and 2 were determined as 7-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-8,8-dimethyl-7,8-dihydro-6H-pyranochromen-2-one (1) and decursinol 3'-O-E-pmethoxycinnamic acid ester (2), respectively and newly reported. Compounds 1 and 2 significantly inhibited AChE activity and ameliorated memory impairment induced in mice by scopolamine (1.0 mg/kg body weight s.c.) as measured in passive avoidance test. We suggest, therefore, that compounds 1 and 2 has both anti-AChE and anti-amnesic activities that may ultimately hold significant therapeutic value in alleviating certain memory impairment observed in Alzheimer's disease.

• Archives of Pharmacal Research
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• 제26권10호
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• pp.821-825
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• 2003

The effects of purple sweet potato anthocyanin (SPA) and Cordyceps mushroom extract (CME) on lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and cognitive deficits were examined. Both SPA and CME exhibited DPPH radical scavenging activities with similar potency. In contrast, only SPA was shown to effectively inhibit lipid peroxidation initiated by $Fe^{2+}$ and ascorbic acid in rat brain homogenates. Furthermore, SPA markedly enhanced cognitive performance, assessed by passive avoidance test in ethanol-treated mice. Combined treatments with SPA and CME did not significantly influence the effects of SPA alone. These results demonstrate that anthocyanin prepared from purple sweet potato exhibits memory enhancing effects, which may be associated with its antioxidant properties.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2006년도 하계종합학술대회
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• pp.995-996
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• 2006

This paper presents a design of the PMOLED(Passive Matrix Organic light emitting diodes) driver IC improving the terminal current offset. The proposed methods are improving the design of the usual data output circuit. This methods can be avoidance brightness non-uniformity problem.

• 생약학회지
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• 제52권1호
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• pp.55-60
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• 2021

Belamcandae Rhizoma (BR), the rhizome of Belamcanda chinensis (L.) DC., possesses various biological properties such as anti-inflammatory activity, antioxidant activity and antimutagenic activity. However, there have been no studies on the anti-amnesic effect of BR. In this study, we assessed the improvement effect of BR extract on scopolamine-induced amnesia in mice. ICR mice were administrated with BR (50, 100 or 200 mg/kg, p.o.) and were subsequently injected of scopolamine (1 mg/kg, i.p.) 30 min before behavioral tasks (Y-maze, passive avoidance and Morris water maze tasks). To further assess the possible mechanisms of BR, the ex vivo acetylcholinesterase (AChE) activity was also evaluated. BR could ameliorate scopolamine-induced memory impairment and could regulate the cholinergic function by inhibiting the AChE activity. These data demonstrated that BR exert candidate extract against amnesia by restoring the cholinergic activity.

• 셀메드
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• 제13권14호
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• pp.14.1-14.9
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• 2023

Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).