• International Journal of Reliability and Applications
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• 제12권1호
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• pp.1-14
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• 2011

This paper discusses the stochastic analysis and the statistical inference of a quadratic failure rate semi-Markov reliability model. Maximum likelihood procedure will be used to obtain the estimators of the parameters included in this reliability model. Based on the assumption that the lifetime and repair time of the system units are random variables with quadratic failure rate, the reliability function of this system is obtained. Also, the distribution of the first passage time of this system is derived. Many important special cases are discussed.

• Asian-Australasian Journal of Animal Sciences
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• 제13권7호
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• pp.913-917
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• 2000

Sixteen adult Barbari bucks were divided into 4 homogeneous groups, each group was offered wheat straw (WS) at levels 75, 100, 125 and 150 per cent of ad libitum intake in a factorial randomized complete block design. All goats were uniformly fed a supplement ($13.5g\;DM/kg\;W^{0.75}$) to fulfill their requirement for protein at maintenance level. The experimental feeding of goats at different levels for 21 days was followed by a digestion trial of 6 days and determination of rate of passage of digesta for 144 h duration, respectively. Intake ($g/kg\;W^{0.75}$) of dry matter (DM), organic matter (OM), digestible DM and digestible OM increased with increase in amount of WS offered. The levels of WS refusals for obtaining upper limit of intake was found to be above 30% of DMO. Concentration of ADF and lignin was significantly lower and CP was higher (p>0.05) in food ingested relative to food offered or refused in response to increasing allowance of WS. Dietary means of particulate rate of passage from rumen, transit time and total mean retention time ranged from 0.032 to 0.036/h, 19.10 to 21.72/h and 58.61 to 61.53/h respectively and did not show significant differences (p>0.05) irrespective of dietary level of WS. The results suggest that DMI and quality of ingested WS would improve with higher rates of offer and refusals (${\geq}30%$ of DMO) without any pronounced effect on passage kinetics of digesta, because of the greater opportunity afforded to goats for selective feeding.

• 한국수정란이식학회지
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• 제27권3호
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• pp.189-192
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• 2012

Although embryonic stem cells (ESCs) or ES-like cells are reported from many mammalian species other than the mouse, the culture system for murine ESCs may not be suitable to the other species. Previously many other research groups have modified either human or mouse ESC culture systems for bovine ESC culture. In this study, we compared three different culture mediums consisting of DMEM, ${\alpha}$-MEM or KnockOut$^{TM}$-DMEM (KO), which are modified from human or mouse ESC culture system, for the generation of bovine ESCs. In this study, some pre-requisite events which are important for establishment and long-term propagation of ESCs such as inner cell mass (ICM) attachment on feeder cells, primary colony formation and sustainability after passaging. Once the ICM clumps attached on feeder cells, this was designated as passage 0. In regards to the rate of ICM attachment, ${\alpha}$-MEM was superior to the other systems. For primary colony formation, there was no difference between DMEM and ${\alpha}$-MEM whereas KO showed lower formation rate than the other groups. For passaging, the colonies were split into 2~4 pieces and passed every 5~6 days. From passage 1 to passage 3, DMEM system seemed to be appropriate for maintaining putative bovine ESCs. On the other hand, ${\alpha}$-MEM tended to be more suitable after passage 6. Although ${\alpha}$-MEM support to maintain a ES-like cell progenies to passage 15, all three culture systems which are modified from human or mouse ESC culture media failed to retain the propagation and long-term culture of putative bovine ESCs. Our findings imply that more optimized alternative culture system is required for establishing bovine ESC lines.

• 한국지능시스템학회논문지
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• 제23권3호
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• pp.220-225
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• 2013

항구 등 선박교통이 밀집된 구역에서 선박의 사고는 빈번하게 발생한다. 해양사고는 한번 발생하면 대형사고로 이어질 확률이 높으므로, 철저한 해상교통관리가 필요하다. 본 연구에서는 실 해역의 통계적인 해상교통정보와 실시간 선박 통항분포를 바탕으로 항로 위험도를 정량적으로 평가하기 위한 시뮬레이터를 개발하고자 한다. 항로 위험도 평가 시뮬레이터는 항로정보 입력부, 통항분포 분석부, 알고리즘 실행부로 구성하였다. 또한 완도해역의 해상교통정보를 시뮬레이터에 적용하여 항로의 정량적인 항로 위험도를 산출하고자 한다.

• 한국가시화정보학회지
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• 제18권2호
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• pp.35-38
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• 2020

Airfryer is used to heat a food up by convecting hot air upward around the food. In this study, we investigated the effect of the bottom-shape of the food container in airfryer on the upward convection velocity of hot air to find an optimal bottom-shape by computational fluid dynamics. Numerical experiments were performed by solving the incompressible Navier-Stokes equations with turbulence model. We found that the maximum upward velocity with concave flow-passage on the bottom was bigger than that with the flat bottom and that the maximum upward convection velocity was achieved when the number of concave flow-passage with fan-shape is around six. The pressure drop by the internal flow was found to increase as the number of the concave flow-passage on the bottom increased probably due to increase of the surface area of the bottom. Therefore, it can be said that the optimal number of the concave flow-passage is around six for the flow rate considered in this study.

• 컴퓨터교육학회논문지
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• 제6권4호
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• pp.23-30
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• 2003

본 논문은 문서 단위 보다 작은 단락 단위의 검색 시스템을 사용하는 효율적인 질의 응답 시스템 개발을 위하여 문서 검색에서 성능이 검증된 Okapi 시스템의 BM25 알고리즘을 응용한 단락 검색 시스템을 제안하고, 단락 검색 시스템의 성능을 분석하고자 한다. 100만 건의 문서로 구성된 TREC Q&A track 테스트 컬렉션을 색인에 사용하고 TREC Q&A track 질의 집합 중 1~100번까지의 질의를 사용하여 실험한 결과 재현율이 100%가 되기 위해서는 문서 검색은 약 12만 문장을 검색해야 하는 반면, 단락 검색에서는 문서 검색의 약 1/70인 1700문장만으로도 100%의 재현율을 얻을 수 있음을 확인하였다.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 동계학술발표대회 논문집
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• pp.67-70
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• 2008

As a part of the project on road tunnel fire safety system development, Quantitative Risk Assessment program was developed. In this study, We carried out Quantitative Risk Assessment with this program by using a factor of cross passage interval, warning announcement time and congestion ratio etc for 1km tunnel with natural ventilation. In the case of 250m below of cross passage interval, Risk value due to warning announcement time was a slightly changed. but if cross passage interval is more than 250m, expected fatalities in the same HRR(heat release rate) was sharp increased. As a result, Quantitative Risk Assessment program which was developed in this research project is possible to risk assessment with ventilation type, cross passage for evacuation and detection system response property etc. hereafter, this program look forward to use as a tool for road tunnel performance based design.

• 한국산업융합학회 논문집
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• 제7권2호
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• pp.153-159
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• 2004

The purpose of this research is to investigate the performance of swirl combustion chamber diesel engine by changing the jet passage area, the depth and shape of the piston top cavity (main chamber). The performance of diesel engine with newly changed swirl combustion chamber was tested through the experimental conditions as engine speed, load and injection timing etc. The test results were compared and analyzed. And another purpose of this research is to make a new diesel engine that is satisfied fuel consumption and regulation value of exhaust gas. 1. The rate of fuel consumption was affected significantly by the jet passage area at the high speed and load than low speed and low load. The influence of jet passage large area was proven to decrease the rate of fuel consumption. 2. Smoke was affected significantly by the depth of the piston top cavity, but exhaust temperature and the rate of fuel consumption wasn't affected. The rate of fuel consumption was affected by changing injection timing. 3. The rate of fuel consumption, exhaust temperature and Smoke were affected significantly by the shape of the piston top cavity from rectangular to trapezoid. That is we have all high value. The exhaust smoke density and exhaust gas temperature depended sensitively on variation of the injection timing rather than the shape of the combustion chamber within the experimental conditions. 4. We made a new diesel engine that is satisfied design target values(sfc=190 g/hr, NOx + THC=6.0 g/KWh, PM=0.3 KWh), the rate of fuel consumption and emission standard etc., through changing injection timing at the maximum torque point and rated power point. Although we have a little high NOx value.

• 한국동물위생학회지
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• 제46권3호
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• pp.193-202
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• 2023

Porcine epidemic diarrhea is an infectious intestinal disease caused by the porcine epidemic diarrhea virus (PEDV). Especially, when suckling piglets are infected, the mortality rate is close to 100%. PEDV is classified into G1 and G2 types based on genetic differences. The G2 type PEDV outbreak in the United States in 2013 was highly pathogenic and contagious, and it has spread worldwide and caused continuous economic losses. Most commercial vaccines used are G1 type vaccines, and existing vaccines do not fully protect piglets due to genetic differences. In this study, we evaluated the safety of the newly developed G2 type attenuated HSGP vaccine strain by inoculating it into piglets and testing whether the vaccine virus spreads to the non-vaccinated, negative pigs and whether the vaccine reverts to its virulence during serial passage experiments. Each experiment lasted for 7 days for each passage, and fecal viral titers, clinical symptoms, and weight gain were measured daily. After the experiment, necropsy was performed to measure intestinal virus titer and pathological evaluation. As a result of the first passage, no transmission of the vaccine virus to negative pigs co-housed with vaccinated pigs was observed. In addition, after four consecutive passage experiments, the clinical symptoms and small intestine lesions were gradually alleviated, and no virus was detected in the feces in the fourth passage experiment. Therefore, it was concluded that the vaccine was safe without virulence reversion in accordance with the guidelines of the current licensing authority. However, further studies are needed on the genetic changes and biological characteristics of the mutant virus that occur during successive passages of the attenuated vaccine since the replication and clinical symptoms of the virus increased until the third passage during successive passages of the vaccine virus. Based on this study, it was concluded that virulence reversion and safety evaluation of attenuated vaccines through serial passage in target animals can be useful to evaluate the safety of attenuated viruses.

• Reproductive and Developmental Biology
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• 제30권1호
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• pp.53-58
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• 2006

본 연구는 한우 성체 유래 귀세포(Korean bovine ear skin fibroblasts, KbESF)와 태아 섬유아세포(Korean bovine fetal fibroblasts, KbFF)를 이용한 체세포 복제(SCNT) 시 세포종류, 배양기간 그리고 융합방법이 핵이식 수정란의 발달에 미치는 영향을 알아보기 위하여 실시하였다. 태아 섬유아세포는 임신 51일령의 한우태아에서 분리하였고, 귀세포는 28개월령의 성우의 귀에서 채취하였다. 세포는 15주 동안 체외에서 배양하며 체세포 핵이식(SCNT)에 공시하였다. 융합방법을 비교하기 위해 챔버방법과 전극 바늘을 이용한 방법으로 핵과 세포질을 융합하였다. 세포의 doubling time은 KbFF에서 17.3시간, KbESF에서 24.3시간으로 나타났다. 핵이식 후 융합과 분할율은 needle 방법에서 보다 유의적으로 높았으나(각 각 76.1과 81.2%, P<0.05), 배반포 발달율은 차이가 없었다. KbESF의 경우, 배반포 발달율은 passage $5{\sim}9$(39.4%)와 $13{\sim}15$(40.4%)에서 passage $1{\sim}4$에 비하여 유의적으로 높았다(P<0.05). KbFF의 경우, 융합율은 passage $5{\sim}8$과 $13{\sim}15$에서 각각 75.0 및 76.8%로 passage $1{\sim}4$(61.5%)보다 높았으나, 난분할율과 배반포 발달율은 차이가 없었다. 결론적으로, SCNT 수정란의 발달은 융합 방법에 의해 영향을 받을 수 있으나, 계대배양 15회까지 장기배양을 한 경우는 복제수정란의 발육에 영향을 주지 않는 것으로 판단된다.