• Title/Summary/Keyword: particle size control

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Decreasing Particle Size of Paclitaxel Using Polymer in Fractional Precipitation Process (고분자물질을 이용한 분별침전 공정에서 파클리탁셀의 입자크기 감소)

  • Kim, Min Jae;Kim, Jin-Hyun
    • Korean Chemical Engineering Research
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    • v.54 no.2
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    • pp.278-283
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    • 2016
  • In this study, we have for the first time applied fractional precipitation with hydrophilic polymer in order to decrease the particle size of the anticancer agent paclitaxel from plant cell cultures. When compared with the case where no hydrophilic polymer was employed, the addition of hydrophilic polymer in fractional precipitation resulted in a decrease in the size of the paclitaxel precipitate. Among the polymers used, HPMC 2910 was the most effective for inhibition of precipitate growth. A polymer concentration of 0.2% (w/v) obtained the smallest particle size. The particle size was reduced by ~35% compared to control. In addition, the precipitate size was inversely correlated with the absolute value of the zeta potential.

Development of Tethered-Balloon Package System for Vertical Distribution Measurement of Atmospheric Aerosols (Tethered-Balloon Package System 개발 및 대기 에어로졸의 연직 분포 측정)

  • Eun, Hee Ram;Lee, Hong Ku;Lee, Yang Woo;Ahn, Kang-Ho
    • Particle and aerosol research
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    • v.9 no.4
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    • pp.253-260
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    • 2013
  • For a vertical atmospheric aerosol distribution measurement, a very compact and light particle sampling package is developed. This package includes a compact optical particle counter (Hy-OPC), a light and small condensation particle counter (Hy-CPC), sensors (GPS, wind velocity, temperature, humidity), and a communication and system control board. This package is attached to He balloon and the altitude is controlled by a winch. Using this system the vertical particle size distribution was measured. The test results showed that the ground base atmospheric particle measurement result may be a lot different from that high above the ground.

Influence of Aftertreatment System on the Size Distribution of Diesel Exhaust Particulate Matter (후처리 장치에 의한 디젤엔진 배출가스의 미세 입자 입경분포 변화)

  • 권순박;김민철;이규원;류정호;엄명도;김종춘;정일룩
    • Transactions of the Korean Society of Automotive Engineers
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    • v.7 no.7
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    • pp.113-121
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    • 1999
  • Diesel particulate matter is known to be one of the major harmful emissions produced by diesel engines. Diesel particulates are subject to diesel emission regulations and have lately become the focus in the diesel emission control technology. Thus, the aftertreatment system is adopted at the diesel engine exhaust to reduce the particulate emission. Although this benefit is recognized, it is not clear how the aftertreatment system influences quantitatively the particle size distribution distribution. In this study, the particle size distributions of diesel exhaust were measured using the scanning mobility particle sizer with and without the aftertreatment system. There results showed that the diesel particulate filter and plasm system reduced the number of emitted particles by more than 90% and about 80% respectivley in the particle size range of 20nm∼600nm. On the other hand no significant effect of the diesel oxidation catalyst on the particle number concentration was detected.

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Effect of Particle size and Blending Ratio on Thermo Reaction and Combustion Characteristics in Co-firing with Bituminous and Sub-bituminous Coals (역청탄과 아역청탄 혼합연소조건에서 입자크기와 혼소율이 열물성반응과 연소특성에 미치는 영향)

  • Sung, Yon-Mo;An, Jae-Woo;Moon, Cheor-Eon;Ahn, Seong-Yool;Kim, Sung-Chul;Seo, Sang-Il;Kim, Tae-Hyung;Choi, Gyung-Min;Kim, Duck-Jool
    • Journal of the Korean Society of Combustion
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    • v.15 no.4
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    • pp.65-73
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    • 2010
  • In order to provide fundamental information for developing reaction model in the practical blended coal power plants, effects of particle size and blending ratio on combustion characteristics and thermal reaction in co-firing with bituminous and sub-bituminous coals were experimentally investigated using a TGA and a laboratory-scale burner. Characteristic parameters including ignition, burnout temperature and activation energy were determined from TG and DTG combustion profiles. Distributions of flame length and mean particle temperature were investigated from the visualization of flames in slit-burner system. As coal particle size decreased and volatile matter content increased, characteristic temperatures and activation energy decreased. The ignition/burnout characteristics and activation energy are linearly influenced by a variation in particle size and blending ratio. These results indicated that the control of the coal blending ratio can improve the combustion efficiency for sub-bituminous coals and the ignition characteristics for bituminous coals.

An Experimental Study on the Characteristics of Direct Photoelectric Charging (직접 광대전의 대전특성에 관한 실험적 연구)

  • Lee, Chang-Sun;Kim, Yong-Jin;Kim, Sang-Sao
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.6
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    • pp.753-759
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    • 2000
  • Photoelectric charging is a very efficient way of charging small particles. This method can be applied to combustion measurement, electrostatic precipitator, metal separation and control of micro-contamination. To understand the photoelectric charging mechanism, particle charging of silver by exposure to ultraviolet is investigated in this study. Average charges and charge distributions are measured at various conditions, using two differential mobility analyzers, a condensation nucleus counter, and an aerosol electrometer. The silver particles are generated in a spark discharge aerosol generator. After that process, the generated particles are charged in the photoelectric charger using low-pressure mercury lamp that emits ultraviolet having wavelength 253.7 nm. The results show that ultra-fine particles are highly charged by the photoelectric charging. The average charges linearly increase with increasing particle size and the charge distribution change with particle size. These results are discussed by comparison with previous experiments and proposed equations. It is assumed that the coefficient of electron emission probability is affected by initial charge. The results also show that the charge distribution of a particle is dependent on initial charge. Single changed particle, uncharged particle and neutralized particle are compared. The differences of charge distribution in each case increase with increasing particle size.

Effect of the C/Si Molar Ratio on the Characteristics of β-SiC Powders Synthesized from TEOS and Phenol Resin (C/Si 몰 비가 TEOS와 페놀수지를 출발원료 사용하여 합성된 β-SiC 분말의 특성에 미치는 영향)

  • Youm, Mi-Rae;Park, Sang-Whan;Kim, Young-Wook
    • Journal of the Korean Ceramic Society
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    • v.50 no.1
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    • pp.31-36
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    • 2013
  • ${\beta}$-SiC powders were synthesized by a carbothermal reduction process using $SiO_2$-C precursors fabricated by a sol-gel process using phenol resin and TEOS as starting materials for carbon and Si sources, respectively. The C/Si molar ratio was selected as an important parameter for synthesizing SiC powders using a sol-gel process, and the effects of the C/Si molar ratio (1.4-3.0) on the particle size, particle size distribution, and yield of the synthesized ${\beta}$-SiC powders were investigated. It was found that (1) the particle size of the synthesized ${\beta}$-SiC powders decreased with an increase in the C/Si molar ratio in the $SiO_2$-C hybrid precursors, (2) the particle size distribution widened with an increase in the C/Si molar ratio, and (3) the yield of the ${\beta}$-SiC powder production increased with an increase in the C/Si molar ratio.

Synthesis of Platinum Nanoparticles by Liquid Phase Reduction (액상환원공정을 이용한 백금 나노 입자의 합성)

  • Lee, Jin-Ho;Kim, Se-Hoon;Kim, Jin-Woo;Lee, Min-Ha;Kim, Young-Do
    • Journal of Powder Materials
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    • v.19 no.1
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    • pp.60-66
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    • 2012
  • In this study, Platinum(Pt) nanoparticles were synthesized by using polyol process which is one of the liquid phase reduction methods. Dihydrogen hexachloroplatinate (IV) hexahydrate $(H_2PtCl_6{\cdot}6H_2O)$, as a precursor, was dissolved in ethylene glycol and silver nitrate ($AgNO_3$) was added as metal salt for shape control of Pt particle. Also, polyvinylpyrrolidone (PVP), as capping agent, was added to reduce the size of particle and to separate the particles. The size of Pt nanoparticles was evaluated particle size analyzer (PSA). The size and morphology of Pt nanoparticles were observed by transmission electron microscopy (TEM) and high resolution TEM (HRTEM). Synthesized Pt nanoparticles were studied with varying time and temperature of polyol process. Pt nanoparticles have been successfully synthesized with controlled sizes in the range 5-10 and 20-40 nm with cube and multiple-cube shapes.

Mechanical Properties of Denture Base Resin through Controlling of Particle Size and Molecular Weight of PMMA (폴리(메틸 메타아크릴레이트) 입자 크기 및 분자량 제어에 따른 의치상 재료로서의 기계적 물성 변화)

  • 양경모;정동준
    • Polymer(Korea)
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    • v.27 no.5
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    • pp.493-501
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    • 2003
  • Poly(methyl methacrylate) (PMMA) particles, denture base resin, were synthesized by suspension polymerization through control of polymerization conditions (stabilizer concentration, co-monomer concentration, and the agitation speed) and evaluated changes in molecular weight and particle size. We also investigated their mechanical properties of compression-molded samples which were from synthesized polymer powder mixed with methyl methacrylate (MMA) solution. under the condition of volumetric ratio as 2:1(PMMA powder and MMA solution). The results shows that the mechanical properties were mainly affected by particle size over 100 ${\mu}$m (in particle size) and by molecular weight under 100 ${\mu}$m (in particle size). From these results, we concluded that the most appropriate particle size of PMMA powder for heat-cured denture base resins is around 100 ${\mu}$m. and its molecular weight is around 300000 (M$\sub$n/).

Numerical Simulation Study on Gas-Particle Two-Phase Jets in a Crossflow (I) -Two-Phase Jet Trajectory and Momentum Transfer Mechanism- (고체입자가 부상된 자유 횡분류 유동에 대한 전산모사 연구 (I) -2상 분류궤적과 운동량 전달기구-)

  • 한기수;정명균
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.15 no.1
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    • pp.252-261
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    • 1991
  • A particle trajectory model to simulate two-phase particle-laden crossjets into two-dimensional horizontal free stream has been developed to study the variations of the jet trajectories and velocity variations of the gaseous and the particulate phases. The following conclusions may be drawn from the predicted results, which are in agreement with experimental observations. The penetration of the two-phase jet in a crossflow is greater than that of the single-phase jet. The penetration of particles into the free stream increases with increasing particle size, solids-gas loading ratio and carrier gas to free stream velocity ratio at the jet exit. When the particle size is large, the solid particles separate from the carrier gas , while the particles are completely suspended in the carrier gas for the case of small size particles. As the particle to carrier gas velocity ratio at the jet exit is less than unity, the particles in the vicinity of the jet exit are accelerated by the carrier gas. As the injection angle is increased, the difference of the particle trajectory from that of the pure gas becomes larger. Therefore, it can be concluded that the velocities and trajectories of the particle-laden jets in a crossflow change depending on the solids-gas loading ratio, particle size, carrier gas to free stream velocity ratio and particle to gas velocity ratio at the jet exit.

Effect of Rice Varieties on the Quality of Dry Milled Rice Flour and Jeolpyeon (쌀 품종이 건식 쌀가루 및 절편의 품질에 미치는 영향)

  • Kim, Kyung-Mi;Kim, Hee-sun;Ra, Ha-Na;Kim, Ha-Yun;Han, Gwi-Jung
    • Journal of the Korean Society of Food Culture
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    • v.34 no.3
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    • pp.334-342
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    • 2019
  • In this study, the effects of different varieties and particle sizes of dry milled rice flour on Jeolpyeon quality were investigated. Classify particle size of dry milled rice flour according to rice variety into 50, 100, and $150{\mu}m$. A particle size of $50{\mu}m$ in the varieties Boramchan and Hanareum resulted in the highest damaged starch contents (p<0.05). Additionally, the Boramchan and Hanareum varieties had the highest water absorption index (WAI) values (p<0.05). Analysis of the gelatinization characteristics of dry milled rice flour according to varieties revealed the peak viscosity of Dasan and Hanareum was high (p<0.05), regardless of particle size, while the breakdown was highest for Hanareum at all particle sizes (p<0.05). The moisture content of Jeolpyeon made with Boramchan varied between 48.83 and 53.64% among particle sizes, with no significant differences relative to the control. The hardness of the control was 3.15 kg, while the hardness of Jeolpyeon made with Boramchan decreased significantly 2.60-2.63 kg (p<0.05).