• Title/Summary/Keyword: partial factor method

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Prediction on the Chiral Behaviors of Drugs with Amine Moiety on the Chiral Cellobiohydrolase Stationary Phase Using a Partial Least Square Method

  • Choi, Sun-Ok;Lee, Seok-Ho;Park Choo , Hea-Young
    • Archives of Pharmacal Research
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    • v.27 no.10
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    • pp.1009-1015
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    • 2004
  • Quantitative Structure-Resolution Relationship (QSRR) using the Comparative Molecular Field Analysis (CoMFA) software was applied to predict the chromatographic behaviors of chiral drugs with an amine moiety on the chiral cellobiohydrolase (CBH) columns. As a result of the Quantitative CoMFA-Resolution Relationship study, using the partial least square method, prediction of the behavior of drugs with amine moiety upon chiral separation became possible from their three dimensional molecular structures. When a mixed mobile phase of 10 mM aqueous phosphate buffer (pH 7.0) - isopropanol (95 : 5) was employed, the best Quantitative CoMFA-Resolution Relationship, derived from the study, provided a cross-validated $q^2$ = 0.933, a normal $r^2$ = 0.995, while the best Quantitative CoMFA-Separation Factor Relationship, also derived from the study, yielded a cross-validated $q^2$ = 0.939, a normal $r^2$ = 0.991. When all of these results are considered, this QSRR-CoMFA analysis appears to be a very useful tool for the preliminary prediction on the chromatographic behaviors of drugs with an amine moiety inside chiral CBH columns.

The Single Phase Converter of Power Factor Collection Type with Simple Switching Method (간이 스위칭법에 의한 단상 역률개선형 컨버터)

  • 문경희;고강훈;김은수;곽동걸;조판제;이현우
    • Proceedings of the KIPE Conference
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    • 1999.07a
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    • pp.323-326
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    • 1999
  • For decrease the harmonic current components of the power source, a first method is insert the choke coil that used the choke input type rectifier, the booster chopper circuit and buck chopper circuit. And the several method are studying like as the PWM(Pulse Width Modulation) converter and the active filter type which is used the high frequency switching and the sinusoidal wave formed input current. In this type, there are many problem as a low efficiency, increased the noise, the high leakage current and cost up by the high frequency switching. For improve this problems, the partial resonan method is used on the booster inducter and lossles snubber condenser. This method decreased the distortion factor has lower harmonic components than the hard switching and there is no switching loss by the ZCS(Zero Current Switching) at switch turn-on and the ZVS(Zero Voltage Swithcing) at switch turn-off

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Experimental Study on the Damping Estimation of the 5×5 Partial Fuel Assembly (5×5 부분핵연료 집합체의 감쇠추정을 위한 실험적 연구)

  • Lee, Kang-Hee;Yoon, Kyung-Ho;Song, Kee-Nam
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.2 s.107
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    • pp.163-168
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    • 2006
  • The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle $(5\times5)$ which is called partial fuel assembly is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid to obtain the Flow-Induced Vibration (FIV) characteristics of the scaled fuel assembly over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the assembly prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the scaled test assembly. For the damping factor of the partial fuel assembly and the grid cage at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the partial fuel assembly is about $0.7\%$ with reasonable error of $2\%$ for the previous results. Nonlinear behavior of the partial fuel assembly might be stem mainly from the rod-grid support configuration.

A Study on PFC AC-DC Converter of High Efficiency added in Electric Isolation (절연형 고효율 PFC AC-DC 컨버터에 관한 연구)

  • Kwak, Dong-Kurl;Kim, Sang-Roan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.7
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    • pp.1349-1355
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    • 2009
  • This paper is studied on a novel power factor correction (PFC) AC-DC converter of high efficiency by soft switching technique. The input current waveform in the proposed converter is got to be a sinusoidal form composed of many a discontinuous pulse in proportion to the magnitude of a ac input voltage under the constant switching frequency. Therefore, the input power factor is nearly unity and the control method is simple. The proposed converter adding an electric isolation operates with a discontinuous current mode (DCM) of the reactor in order to obtain some merits of simpler control, such as fixed switching frequency, without synchronization control circuit used in continuous current mode (CCM). To achieve the soft switching (ZCS or ZVS) of control devices, the converter is constructed with a new loss-less snubber for a partial resonant circuit. It is that the switching losses are very low and the efficiency of the converter is high, Particularly, the stored energy in a loss-less snubber capacitor recovers into input side and increases input current from a resonant operation. The result is that the input power factor of the proposed converter is higher than that of a conventional PFC converter. This paper deals mainly with the circuit operations, theoretical, simulated and experimental results of the proposed PFC AC-DC converter in comparison with a conventional PFC AC-DC converter.

Sensitivity Analysis by Parametric Study of Load Factor for a Concrete Box Girder Railway Bridge Using Limit State Design

  • Yeo, Inho;Sim, Hyung-Bo;Kim, Daehwan;Kim, Yonghan
    • International Journal of Railway
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    • v.8 no.1
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    • pp.5-9
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    • 2015
  • Reliability based limit state design method is replacing traditional deterministic designs such as allowable stress design and/or ultimate strength design methods in world trends. European design code(Eurocode) has adopted limit state design, and Korea road bridge design standard has also recently been transferred to limit state design method. In this trend, Korea railroad design standard is also preparing for adopting the same design concept. While safety factors are determined empirically in traditional design, load combinations as well as load factors are determined by solving limit state equations. General partial safety factors are evaluated by using AFORM(Advanced First Order Reliability Method) in the reliability based limit state design method. In this study sensitivity analysis is carried out for a dead load factor and a live load factor. Relative precisions of the dead load and the live load factors are discussed prior to the AFORM analysis. Furthermore the sectional forces of design and the material quantities required by two different design methods are compared for a PSC box girder railway bridge.

Electrical Parameter Extraction of High Performance Package Using PEEC Method

  • Pu, Bo;Lee, Jung-Sang;Nah, Wan-Soo
    • Journal of electromagnetic engineering and science
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    • v.11 no.1
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    • pp.62-69
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    • 2011
  • This paper proposes a novel electrical characterization approach for a high-performance package system using an improved Partial Element Equivalent Circuit (PEEC). As the effect of interconnects becomes a pivotal factor for the performance of high-speed electronic systems, there is a great demand for an accurate equivalent model for interconnects. In particular, an equivalent model of interconnects is established in this paper for the Fine-Pitch Ball Grid Array (FBGA) package using the improved PEEC method. Based on the equivalent model, electrical characteristics are analyzed; furthermore, these are verified through the measurement results of a Vector Network Analyzer (VNA).

The Photovoltaic generation control system using partial resonant method (부분공진기법을 이용한 태양광발전 제어시스템)

  • 고강훈;이현우;김영철;최광주
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.14 no.4
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    • pp.16-22
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    • 2000
  • This paper describes Transformer-less type utility interactive system that is combined with buck/boost chopper applying partial resonant method, which remove Transformer, and high efficient PWM inverter. Therefore, it is possible to make it lightweight, to cut down the cost, and to improve its reliability. What the merits of this system are that we can transmit arbitrary power arbitrary power to load and utility regardless of generating voltage magnitude of solar cell and we can always obtain high factor controlling by equal phase signal with utility.

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Reliability-based assessment of damaged concrete buildings

  • Sakka, Zafer I.;Assakkaf, Ibrahim A.;Qazweeni, Jamal S.
    • Structural Engineering and Mechanics
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    • v.65 no.6
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    • pp.751-760
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    • 2018
  • Damages in concrete structures due to aging and other factors could be a serious and immense matter. Making the best selection of the most viable and practical repairing and strengthening techniques are relatively difficult tasks using traditional methods of structural analyses. This is due to the fact that the traditional methods used for assessing aging structure are not fully capable when considering the randomness in strength, loads and cost. This paper presents a reliability-based methodology for assessing reinforced concrete members. The methodology of this study is based on probabilistic analysis, using statistics of the random variables in the performance function equations. Principles of reliability updating are used in the assessment process, as new information is taken into account and combined with prior probabilistic models. The methodology can result in a reliability index ${\beta}$ that can be used to assess the structural component by comparing its value with a standard value. In addition, these methods result in partial safety factor values that can be used for the purpose of strengthening the R/C elements of the existing structure. Calculations and computations of the reliability indices and the partial safety factors values are conducted using the First-order Reliability Method and Monte Carlo simulation.

Stress Intensity Factor of Single Edge Cracked Plates Considering Materials and Geometry of Patch by p-Convergent Partial Layerwise Model (p-수렴 부분층별모델에 의한 일변균열판의 패치재료 및 기하형상에 따른 응력확대계수)

  • Ahn, Hyeon-Ji;Ahn, Jae-Seok;Woo, Kwang-Sung
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.23 no.2
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    • pp.191-198
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    • 2010
  • This study investigated that the stress reduction of single edge cracked plates with patch repairs according to different type of patching such as material, size and thickness of patch and adhesive as well as single sided or double sided patches. As a numerical tool, the p-convergent partial layerwise model has been employed. The proposed model is formulated by assuming piecewise linear variation of in-plane displacement and a constant value of out-of-plane displacements across thickness. The integrals of Legendre polynomials are chosen to define displacement fields and Gauss-Lobatto numerical integration is implemented in order to directly obtain maximum values occurred at the nodal points of each layer without other extrapolation techniques. Also, total strain energy release rate method is adopted to obtain stress intensity factors. Numerical examples are presented not only to demonstrate the stress reduction effect in terms of non-dimensional stress intensity factor and deflection with respect to different type of patch repairs, but also the accuracy of proposed model.

Effects of Social Support on Aggression in Adolescents: The Mediating Role of Grit (청소년의 사회적 지지가 공격성에 미치는 영향: 그릿의 매개효과)

  • Shin, Myung-Oag;Bang, Hae-Soon
    • Journal of Industrial Convergence
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    • v.20 no.10
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    • pp.147-156
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    • 2022
  • The purpose of this paper was to verify the mediated effect of grit in the relationship with the effect of youth social support on aggression. To this end, data from the 2018 Children and Youth Panel (KCYPS) survey were used, and 2,590 first-year middle school students were selected and analyzed. As for the analysis method, Baron & Kenny's regression analysis and Sobel Test were performed. As a result of the main analysis, first, it was found that grit had a partial mediating effect in the effect of parental support, a sub-factor of social support of adolescents, on aggression. Second, it was found that grit had a partial mediating effect in the effect of friend support, a sub-factor of social support of adolescents, on aggression. Third, it was found that grit had a partial mediating effect in the effect of teacher support, a sub-factor of social support of adolescents, on aggression. Based on the above research results, various program development and policy alternatives that can reduce youth aggression and improve grit were suggested.