• Title/Summary/Keyword: parallel structure analysis

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cDNA Cloning, Sequence Analysis and Molecular Modeling of a New Peptide from the Scorpion Buthotus saulcyi Venom

  • Nikkhah, Maryam;Naderi-Manesh, Hossein;Taghdir, Majid;Talebzadeh, Mehdi;Sadeghi-Zadeh, Majid;Schaller, Janatan;Sarbolouki, Mohamad N.
    • BMB Reports
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    • v.39 no.3
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    • pp.284-291
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    • 2006
  • In this study, the cDNA of a new peptide from the venom of the scorpion, Buthotus saulcyi, was cloned and sequenced. It codes for a 64 residues peptide (Bsaul1) which shares high sequence similarity with depressant insect toxins of scorpions. The differences between them mainly appear in the loop1 which connects the $\beta$-strand1 to the $\alpha$-helix and seems to be functionally important in long chain scorpion neurotoxins. This loop is three amino acids longer in Bsaul1 compared to other depressant toxins. A comparative amino acid sequence analysis done on Bsaul1 and some of $\alpha$-, $\beta$-, excitatory and depressant toxins of scorpions showed that Bsaul1 contains all the residues which are highly conserved among long chain scorpion neurotoxins. Structural model of Bsaul1 was generated using Ts1 (a $\beta$-toxin that competes with the depressant insect toxins for binding to $Na^+$ channels) as template. According to the molecular model of Bsaul1, the folding of the polypeptide chain is being composed of an anti-parallel three-stranded $\beta$-sheet and a stretch of $\alpha$-helix, tightly bound by a set of four disulfide bridges. A striking similarity in the spatial arrangement of some critical residues was shown by superposition of the backbone conformation of Bsaul1 and Ts1.

Development of 6-axis force/moment sensor for an intelligent robot's foot (지능형 로봇 발을 위한 6 축 힘/모멘트센서 개발)

  • Kim, Gab-Soon;Shin, Hyi-Jun;Hu, Duk-Chan;Yoon, Jung-Won
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.1097-1102
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    • 2007
  • This paper describes the development of 6-axis force/moment sensor for an intelligent robot's foot. In order to walk on uneven terrain safely, the foot should perceive the applied forces Fx, Fy, Fz and moments Mx, My, Mz to itself. The applied forces and moments should be measured from a 6-axis force/moment sensor attached to a humanoid robot's foot(ankle). They in the published paper already have some disadvantage in the size of the sensor, the rated output and so on. The rated output of each component sensor (6-axis force/moment sensor) is very important to design the 6-axis force/moment sensor for precision measurement. Therefore, each sensor should be designed to be gotten similar the rated output under each rated load. So, the sensing elements of the 6-axis force/moment sensor should get lots of design variables. Also, the size of 6- axis force/moment sensor is very important for mounting to robot's foot. In this paper, a 6-axis force/moment sensor for perceiving forces and moments in a humanoid robot's foot was developed using many PPBs (parallel plate-beams). The structure of the sensor was newly modeled, and the sensing elements (plate-beams) of the sensor were designed using FEM (Finite Element Method) analysis. Then, the 6-axis force/moment sensor was fabricated by attaching strain-gages on the sensing elements, and the characteristic test of the developed sensor was carried out. The rated outputs from FEM analysis agree well with that from the characteristic test.

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Characteristic Analysis of Inductive Power Transfer System for PRT (소형궤도 열차용 유도 전력 전송 시스템 특성해석)

  • Min, Byung-Hun;Lee, Byung-Song
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.3
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    • pp.35-43
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    • 2007
  • In this paper, the inductive power collector using electromagnetic induction for vehicle such as the PRT(Personal Rapid Transit) system is suggested and son ideas for power collector design to improve tile power transfer performance are presented. And also, the analysis of the inductive power transfer system in conjunction with series resonant converter operating variable high frequency is shown. Of particular interest is the sensitivity of the complete system to variations in operational frequency and parameters. In inductive power transfer system electrical power is transferred from a primary winding in the form of a coil or tract to one or more isolated pick-up coils that my relative to the primary. The ability to transmit power without contact enables high reliability and easy maintenance that allows inductive power transfer system to be implemented in hostile environments. This technology has found application in many fields such as electric vehicles, PRT(Personal Rapid Transit) etc. But, low output power is generated due to a loosely coupled characteristic of the large air-gap. Therefore, we will show you various characteristic of inductive power transfer system as double layer construction of secondary winding, which was divided in half to increase both output current and output voltage, a model of power collector and parallel winding structure, a model of concentration/ decentralization winding and the effects of parameter and operational frequency variation.

A negative stiffness inerter system (NSIS) for earthquake protection purposes

  • Zhao, Zhipeng;Chen, Qingjun;Zhang, Ruifu;Jiang, Yiyao;Pan, Chao
    • Smart Structures and Systems
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    • v.26 no.4
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    • pp.481-493
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    • 2020
  • The negative stiffness spring and inerter are both characterized by the negative stiffness effect in the force-displacement relationship, potentially yielding an amplifying mechanism for dashpot deformation by being incorporated with a series tuning spring. However, resisting forces of the two mechanical elements are dominant in different frequency domains, thus leading to necessary complementarity in terms of vibration control and the amplifying benefit. Inspired by this, this study proposes a Negative Stiffness Inerter System (NSIS) as an earthquake protection system and developed analytical design formulae by fully utilizing its advantageous features. The NSIS is composed of a sub-configuration of a negative stiffness spring and an inerter in parallel, connected to a tuning spring in series. First, closed-form displacement responses are derived for the NSIS structure, and a stability analysis is conducted to limit the feasible domains of NSIS parameters. Then, the dual advantageous features of displacement reduction and the dashpot deformation amplification effect are revealed and clarified in a parametric analysis, stimulating the establishment of a displacement-based optimal design framework, correspondingly yielding the design formulae in analytical form. Finally, a series of examples are illustrated to validate the derived formulae. In this study, it is confirmed that the synergistic incorporation of the negative stiffness spring and the inerter has significant energy dissipation efficiency in a wide frequency band and an enhanced control effect in terms of the displacement and shear force responses. The developed displacement-based design strategy is suitable to utilize the dual benefits of the NSIS, which can be accurately implemented by the analytical design formulae to satisfy the target vibration control with increased energy dissipation efficiency.

Expression of Rat Hepatic Glutathione-S-Transferases by Benzoazoles (Benzoazole계 화합물이 glutathione-S-transferases의 유도발현에 미치는 영향)

  • 서경원;김연정;김태완;김효정;조민경;김상건
    • Environmental Analysis Health and Toxicology
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    • v.13 no.3_4
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    • pp.55-61
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    • 1998
  • Glutathione-S-transferases (GSTs) detoxify electrophilic xenobiotics and reactive metabolites. Recently benzene-fused heterocycles have been shown to increase the total amount of hepatic GSTs in rats. Primarily this study aimed to determine the induction of GSTs by benzoazoles (BAs) including benzoxazole (BX), 2-methylbenzoxazole (M-BX), 2,5-dimethyl benzoxazole (D-BX), benzothiazole (BT), aminobenzothiazole (A-BT) and 2-mercaptobenzothiazole (M-BT) in rats. Hepatic cytosol and poly(A)$^+$ mRNA were prepared from rats after oral administration of BX, BT, M-BX, D-BX, A-BT and M-BT for 5 consecutive days at doses of 1 mmol/kg. Western immunoblot and northern blot analysis were conducted with rabbit anti-GST Ya, Yb$_1$, Yb$_2$, Yc antibodies and cDNA probes containing = 500 bps in the specific coding regions of Ya, Yb$_1$, Yb$_2$, Yc$_1$, and Yc$_2$, respectively. All BAs increased the amount of enzymes and mRNA levels of GSTs. BT was the most effective inducer of GSTs among the compounds examined in this study. Although A-BT and M-BT, the derivatives of BT, induced GSTs, these chemicals had lesser effect on induction of GSTs than BT. The derivatives of BX also induced less GSTs than the parent compound and the addition of methyl group to the benzene ring of BX reduced the induction of GSTs. BAs had better inductive effects on the class $\alpha$(Ya, Yc) than class $\mu$ GSTs (Yb$_1$, Yb$_2$). BAs enhanced mRNA levels of GSTs in parallel with the protein levels. These results indicate that 1) most of BAs induced various isozymes of GSTs, 2) the induction of GSTs appears to be correlated with the chemical structure of the derivatives, and 3) the expression of GST by BAs is presumably under the transcriptional regulation.

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Development of Pulsating Type Electromagnetic Hammer Drive Systems (맥동파 전자해머 구동시스템의 개발)

  • Ahn, Dong-Jun;Nam, Hyun-Do
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.5
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    • pp.269-274
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    • 2016
  • This paper proposes the development of a low frequency electronic hammer drive system that is used to prevent scaling or clogging in the hopper process. The electro-mechanical hammering driving method involves the generation of vibration and impact energy. The operation principles of the electromagnetic hammer were considered by parallel/series spring coefficient analysis and the amount of kinetic energy generated was calculated from the product of the equivalent spring constant, which is coupled with the E core and the gap of between the E core and I core. In addition, the Pulsation Driving algorithm was applied to the proposed electromagnetic hammer to obtain the maximizing kinetic energy. This algorithm was then implemented by a logical AND operation process and micro-controller (atmega128) built in functions with a timer interrupt and PWM generation function. The driving circuit of the electromagnetic hammer was designed using the H-bridge type IGBT circuit. The experimental test was performed by usefulness of the developed electromagnetic hammer systems with the acceleration measurement method. The experimental result showed that the proposed system has good kinetic energy generation performance and can be applied to the hopper process.

Development and Application of IoT-based Contactless Ultraosonic System (IoT 기반 비접촉 초음파 측정 시스템 개발 및 적용)

  • Kim, Jihwan;Hong, Jinyoung;Kim, Rrulri;Woo, Ukyong;Choi, Hajin
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.24 no.3
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    • pp.70-79
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    • 2020
  • The main objective of this research to develop an IoT based wireless contactless ultrasonic system (ICUS) and its application to concrete structure. The developed system consists of 16 mems, 2Mhz digitizer, amplifying circuit, FPGA, and wifi module, enabling to measure leaky surface waves from concrete specimens without physical coupling process and wires. Multi-channel analysis is performed to improve the accuracy of data analysis, and the velocity of leaky surface waves and acoustics are derived. Field inspection of railroad concrete sleepers is conducted to evaluate the performance of the system and to compare the results with conventional ultrasonic pulse velocity (UPV). As a result of the field inspection, UPV was limited to evaluate damages. This is because crack pattern of railroad sleepers is parallel to ultrasonic ray path and accessibility of the railroad at the field is disadvantageous to contact-based UPV. On the other hand, ICUS possibly detect the damages as reduction of dynamic modulus by up to 59% compared to non-damaged specimen.

Seismic AVO Analysis, AVO Modeling, AVO Inversion for understanding the gas-hydrate structure (가스 하이드레이트 부존층의 구조파악을 위한 탄성파 AVO 분석 AVO모델링, AVO역산)

  • Kim Gun-Duk;Chung Bu-Heung
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.643-646
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    • 2005
  • The gas hydrate exploration using seismic reflection data, the detection of BSR(Bottom Simulating Reflector) on the seismic section is the most important work flow because the BSR have been interpreted as being formed at the base of a gas hydrate zone. Usually, BSR has some dominant qualitative characteristics on seismic section i.e. Wavelet phase reversal compare to sea bottom signal, Parallel layer with sea bottom, Strong amplitude, Masking phenomenon above the BSR, Cross bedding with other geological layer. Even though a BSR can be selected on seismic section with these guidance, it is not enough to conform as being true BSR. Some other available methods for verifying the BSR with reliable analysis quantitatively i.e. Interval velocity analysis, AVO(Amplitude Variation with Offset)analysis etc. Usually, AVO analysis can be divided by three main parts. The first part is AVO analysis, the second is AVO modeling and the last is AVO inversion. AVO analysis is unique method for detecting the free gas zone on seismic section directly. Therefore it can be a kind of useful analysis method for discriminating true BSR, which might arise from an Possion ratio contrast between high velocity layer, partially hydrated sediment and low velocity layer, water saturated gas sediment. During the AVO interpretation, as the AVO response can be changed depend upon the water saturation ratio, it is confused to discriminate the AVO response of gas layer from dry layer. In that case, the AVO modeling is necessary to generate synthetic seismogram comparing with real data. It can be available to make conclusions from correspondence or lack of correspondence between the two seismograms. AVO inversion process is the method for driving a geological model by iterative operation that the result ing synthetic seismogram matches to real data seismogram wi thin some tolerance level. AVO inversion is a topic of current research and for now there is no general consensus on how the process should be done or even whether is valid for standard seismic data. Unfortunately, there are no well log data acquired from gas hydrate exploration area in Korea. Instead of that data, well log data and seismic data acquired from gas sand area located nearby the gas hydrate exploration area is used to AVO analysis, As the results of AVO modeling, type III AVO anomaly confirmed on the gas sand layer. The Castagna's equation constant value for estimating the S-wave velocity are evaluated as A=0.86190, B=-3845.14431 respectively and water saturation ratio is $50\%$. To calculate the reflection coefficient of synthetic seismogram, the Zoeppritz equation is used. For AVO inversion process, the dataset provided by Hampson-Rushell CO. is used.

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A Polarization-based Frequency Scanning Interferometer and the Measurement Processing Acceleration based on Parallel Programing (편광 기반 주파수 스캐닝 간섭 시스템 및 병렬 프로그래밍 기반 측정 고속화)

  • Lee, Seung Hyun;Kim, Min Young
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.8
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    • pp.253-263
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    • 2013
  • Frequency Scanning Interferometry(FSI) system, one of the most promising optical surface measurement techniques, generally results in superior optical performance comparing with other 3-dimensional measuring methods as its hardware structure is fixed in operation and only the light frequency is scanned in a specific spectral band without vertical scanning of the target surface or the objective lens. FSI system collects a set of images of interference fringe by changing the frequency of light source. After that, it transforms intensity data of acquired image into frequency information, and calculates the height profile of target objects with the help of frequency analysis based on Fast Fourier Transform(FFT). However, it still suffers from optical noise on target surfaces and relatively long processing time due to the number of images acquired in frequency scanning phase. 1) a Polarization-based Frequency Scanning Interferometry(PFSI) is proposed for optical noise robustness. It consists of tunable laser for light source, ${\lambda}/4$ plate in front of reference mirror, ${\lambda}/4$ plate in front of target object, polarizing beam splitter, polarizer in front of image sensor, polarizer in front of the fiber coupled light source, ${\lambda}/2$ plate between PBS and polarizer of the light source. Using the proposed system, we can solve the problem of fringe image with low contrast by using polarization technique. Also, we can control light distribution of object beam and reference beam. 2) the signal processing acceleration method is proposed for PFSI, based on parallel processing architecture, which consists of parallel processing hardware and software such as Graphic Processing Unit(GPU) and Compute Unified Device Architecture(CUDA). As a result, the processing time reaches into tact time level of real-time processing. Finally, the proposed system is evaluated in terms of accuracy and processing speed through a series of experiment and the obtained results show the effectiveness of the proposed system and method.

Performance Evaluation of Multi-User Detectors Employing Subtractive Interference Cancellation Schemes for a DS-CDMA System (감산형 간섭제거기법을 적용한 DS-CDMA 다중사용자 검파기의 성능분석)

  • Seo, Jung-Wook;Kim, Young-Chul;Oh, Chang-Heon;Ko, Bong-Jin;Cho, Sung-Joon
    • Journal of Advanced Navigation Technology
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    • v.6 no.1
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    • pp.17-26
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    • 2002
  • In this paper, we have analyzed the BER (Bit Error Rate) performance of multi-user detectors employing SIC(Successive Interference Cancellation) and PIC (Parallel Interference Cancellation) which are the representative schemes in the subtractive interference cancellation. We have considered the MUD structure employing HIC (Hybrid Interference Cancellation) which combines SIC with PIC scheme, and then analyzed the BER performance. We have evaluated the BER performance of SIC and HIC schemes which execute the soft decision to generate the tentative data bit for the purpose of the interference cancellation in MAI and noise environments. Through the numerical analysis and computer simulation, it is shown that HIC can remove the effect of MAI more efficiently than the others, that improve the BER performance and increase the capacity of DS-CDMA systems regardless of the power control conditions. The reason is that the SIC scheme in front of HIC can solve the near-far problem caused by the imperfect power control and PIC scheme in the rear of it can improve the performance much more.

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