• Journal of Radiation Protection and Research
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• v.37 no.1
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• pp.41-49
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• 2012

The objective of this study is for development of the reference Korean female phantom, HDRK-Woman. The phantom was constructed by adjusting a Korean woman voxel phantom to the Reference Korean data. The Korean woman phantom had been developed based on the high-resolution color slice images obtained from an adult Korean female cadaver. There were a total of 39 organs including the 27 organs specified in ICRP 103 for effective dose calculation. The voxel resolution of the phantom was $1.976{\times}1.976{\times}2.0619\;mm^3$ and the voxel array size is $261{\times}109{\times}825$ in the x, y and z directions. Then, the voxel resolution was changed to $2.0351{\times}2.0351{\times}2.0747\;mm^3$ for adjustment of the height and total bone mass of the phantom to the Reference Korean data. Finally, the internal organs and tissue were adjusted using in-house software program developed for 3D volume adjustment of the organs and tissue. The effective dose values of HDRK phantoms were calculated for broad parallel photon beams using MCNPX Monte Carlo code and compared with those of ICRP phantoms.

• Journal of Dental Rehabilitation and Applied Science
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• v.27 no.4
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• pp.371-392
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• 2011

The purpose of this study was to comparatively analyze the stress distribution according to the inclinations of abutments and angulations of the implant fixtures under occlusal loading force. Three study models with straight and $15^{\circ}$ and $25^{\circ}$-angled abutments were prepared following the insertion of Implants parallel to the long axis of the tooth. Additional two experimental models were fabricated with $15^{\circ}$ and $25^{\circ}$ fixture inclinations. Using ANSYS 11, a finite element analysis program, the magnitudes of stress distribution were analyzed. The magnitude of stress under loading was lowest when the load was applied vertically onto the axis of implant. And the magnitude of stress under compound(vertical+oblique) loading was increased as the inclination of implant abutment and fixture was increase. But, the distribution of stress was different as the loading conditions, because of the horizontal offset. As the offset between the axis of loading and the central axis of the implant increased, the stress was increased.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.188-198
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• 2013

In order to increase its performance, NAND flash memory-based storage is composed of data buses that are shared by a number of flash memories and uses a parallel technique that can carry out multiple flash memory operations simultaneously. Since the storage performance is strongly influenced by the performance of each data bus, it is important to improve the utilization of the bus by ensuring effective scheduling of operations by the storage controller. However, this is difficult because of dynamic changes in buses due to the unique characteristics of each operation with different timing, cost, and usage by each bus. Furthermore, the scheduling technique for increasing bus utilization may cause unanticipated operation delay and wastage of storage resource. In this study, we suggest various dynamic operation scheduling techniques that consider data bus performance and storage resource efficiency. The proposed techniques divide each operation into three different stages and schedule each stage depending on the characteristics of the operation and the dynamic status of the data bus. We applied the suggested techniques to the controller and verified them on the FPGA platform, and found that program operation decreased by 1.9% in comparison to that achieved by a static scheduling technique, and bus utilization and throughput was approximately 4-7% and 4-19% higher, respectively.

• Journal of the Korean Society of Radiology
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• v.11 no.7
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• pp.679-685
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• 2017

Computed tomography has widely been used to diagnose patient disease, and patient dose also increase rapidly. To reduce the patient dose by CT, various techniques have been applied. The iterative reconstruction is used in view of image reconstruction. Image quality of the reconstructed section image through algebraic reconstruction technique, one of iterative reconstruction methods, was examined by the normalized root mean square error. The computer program was written with the Visual C++ under the parallel beam geometry, Shepp-Logan head phantom of $512{\times}512$ size, projections of 360, and detector-pixels of 1,024. The forward and backward projection was realized by Joseph method. The minimum NRMS of 0.108 was obtained after 10 iterations in the regularization parameter of 0.09-0.12, and the optimum image was obtained after 8 and 6 iterations for 0.1% and 0.2% noise. Variation of optimum value of the regularization parameter was observed according to the phantom used. If the ART was used in the reconstruction, the optimal value of the regularization parameter should be found in the case-by-case. By finding the optimal regularization parameter in the algebraic reconstruction technique, the reconstruction time can be reduced.

• Journal of Periodontal and Implant Science
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• v.47 no.3
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• pp.143-153
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• 2017

Purpose: The aim of the present exploratory study was to evaluate extraction socket healing at sites with a history of periodontal and endodontic pathology. Methods: The mandibular 4th premolar teeth in 5 adult beagle dogs served as experimental units. Periodontal and endodontic lesions were induced in 1 premolar site in each animal using wire ligatures and pulpal exposure over 3 months (diseased sites). The contralateral premolar sites served as healthy controls. The mandibular 4th premolar teeth were then extracted with minimal trauma, followed by careful wound debridement. The animals were sacrificed at days 1, 7, 30, 60, and 90 post-extraction for analysis, and the healing patterns at the healthy and diseased extraction sites were compared using radiography, scanning electron microscopy, histology, and histometry. Results: During the first 7 days of healing, a significant presence of inflammatory granulation tissue was noted at the diseased sites (day 1), along with a slightly accelerated rate of fibrin clot resolution on day 7. On day 30, the diseased extraction sites showed a greater percentage of persistent fibrous connective tissue, and an absence of bone marrow formation. In contrast, healthy sites showed initial signs of bone marrow formation on day 30, and subsequently a significantly greater proportion of mature bone marrow formation on both days 60 and 90. Radiographs exhibited sclerotic changes adjoining apical endodontic lesions, with scanning electron microscopy showing collapsed Volkmann canals protruding from these regions in the diseased sites. Furthermore, periodontal ligament fibers exhibited a parallel orientation to the alveolar walls of the diseased sites, in contrast to a perpendicular arrangement in the healthy sites. Conclusions: Within the limitations of this study, it appears that a history of periodontal and endodontic pathology may critically affect bone formation and maturation, leading to delayed and compromised extraction socket healing.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.3
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• pp.1049-1061
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• 2013

In this paper, a relative heat exchange rate is numerically compared for cast-in-place concrete energy piles with different heat exchange pipe configurations, and a new design method for energy piles is proposed. An equivalent heat exchange rate was estimated for the W-type (one series loop), multiple U-type (four parallel loops), and coil-type heat exchanger installed in the same large-diameter drilled shaft. In order to simulate a cooling operation in summer by a CFD analysis, the LWT (leaving water temperature) into a energy pile was fixed at $35^{\circ}C$ and then the EWT (entering water temperature) into a heat pump was monitored. In case of continuously applying the artificial maximum cooling load for 100 hours, all of the three types of heat exchangers show the marginally similar heat exchange rate. However, in case of intermittently applying the cooling load with a cycle of 8 hours operation-16 hours off for 7 consecutive days, the coil type heat exchanger exhibits a heat exchange rate only 86 % of the multiple U-type due to measurable thermal interference between pipe loops in the energy pile. On the other hand, the W-type possesses the similar heat exchange rate to the multiple U-type. The equivalent heat exchange rates for each configuration of heat exchangers obtained from the CFD analysis were adopted for implementing the commercial design program (PILESIM2). Finally, a design method for cast-in-place concrete energy piles is proposed along with a design chart in consideration of typical design factors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.4
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• pp.1576-1581
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• 2013

In the present study, the performance of a PF heat exchanger for heat pump dryer was investigated. Capacity and dehumidification amount of the PF heat exchangers(PF1, PF2, PF3) by different inclination angles($0^{\circ}$, $30^{\circ}$, $60^{\circ}$) were studied. Experimental conditions were an air velocity crossing to the heat exchanger(0.5m/s), an air dry-bulb temperature($60^{\circ}C$) and relative humidity(70%). The experimental results have shown that the performance of the inclined PF heat exchangers was better than that of the vertically installed one. PF3 showed better performance compared to PF1 and PF2 due to the large pin pitch which are leading to more draining for dehumidified water. But, capacity and dehumidification amount of the PF heat exchanger at the inclination angles of $60^{\circ}$ was decreased due to pressure drop. Also, to predict the experimental data of the PF heat exchanger, the performance program was developed for the inclination angles of $0^{\circ}$. PF heat exchanger performance between experiment data and calculation data was satisfied within the maximum 2% for capacity and 3% for dehumidification amount.

• Proceedings of the Korean Society of Toxicology Conference
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• 2006.11a
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• pp.65-74
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• 2006

Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

• Journal of Broadcast Engineering
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• v.15 no.2
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• pp.205-216
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• 2010

In this paper, a method of MPEG-2 Transport Stream (TS) multiplexing for Ultra HDTV (UHDTV) and its design and implementation as a SW tool is described. In practice, UHD video may be divided into several HD videos and each video is encoded in parallel. Therefore, it is necessary to synchronize and multiplex multiple bitstreams encoding each HD video for transmitting and storing UHD video. In this paper, it is assumed that 4 HD videos partitioning a UHD spatially are encoded as H.264/AVC and two 5.0 channel audios are encoded by AC-3. Therefore, 4 H.264/AVC elementary streams (ESs) and 2 AC-3 ESs is mainly considered in the TS multiplexing of UHD. For the carriage of H.264/AVC and AC-3 over MPEG-2 TS, PES packetization and TS multiplexing are designed and implemented based on the extended specification of the MPEG-2 Systems and ATSC (Digital audio compressed standard), respectively. The implemented UHD TS multiplexing tool emulates real time HW operation in the time unit corresponding to the duration of one TS packet transmission in a given TS rate. In particular, in order to satisfy the timing model, the buffers defined in the TS System Target Decoder (T-STD) are monitored and their statuses are considered in the scheduling of TS multiplexing. For UHD multiplexing, two kinds of multiplexing structures, which are UHD re-multiplexing and UHD program multiplexing, are implemented and their strength and weakness are investigated. The developed UHD TS multiplexing tool is tested and verified in terms of the syntax and semantics conformance and functionalities by using a commercial analyzer and real-time presentation tools.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.45 no.1
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• pp.37-47
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• 2008

Exploitation of address generation units which are typically provided in DSPs plays an important role in DSP code generation since that perform fast address computation in parallel to the central data path. Offset assignment is optimization of memory layout for program variables by taking advantage of the capabilities of address generation units, consists of memory layout generation and address pointer assignment steps. In this paper, we propose an effective address pointer assignment method to minimize the number of address calculation instructions in DSP code generation. The proposed approach reduces the time complexity of a conventional address pointer assignment algorithm with fixed memory layouts by using minimum cost-nodes breaking. In order to contract memory size and processing time, we employ a powerful pruning technique. Moreover our proposed approach improves the initial solution iteratively by changing the memory layout for each iteration because the memory layout affects the result of the address pointer assignment algorithm. We applied the proposed approach to about 3,000 sequences of the OffsetStone benchmarks to demonstrate the effectiveness of the our approach. Experimental results with benchmarks show an average improvement of 25.9% in the address codes over previous works.