• Parasites, Hosts and Diseases
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• 제22권1호
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• pp.43-50
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• 1984

이형흡충류의 하나인 Stellantchasmus falcatu에 의한 인체기생 2례가 praziquantel투약후 성충을 수집함으로써 화인되었다. 환자는 서울에 거주하는 24세 (제 1례) 및 55세 (제 2례) 남여로 제 1페는 설사, 복통 등 소화기증상과 불정맥(arrhythmia) 등 심식증상을 호소하면서 대편내에 광절렬류조충란이 양성이었고 제 2례는 소화불량과 조충류 편절 배출을 호소하였다. 조충감염 치료를 위해 praziquantel 15∼20mg/kg를 투여하고 MgSO4 30g으로 충체배출을 유도한 바 배출된 조충을 각각 확인하였다. 그러나 나머지 설사편을 입체해부현미경으로 세밀히 조사한 결과 제 1례에서는 188마리의 S. falcatus와 다른 3종의 이형흡충류가, 제 2례에서는 5마리의 S. falcatus가 수집되었다. 환자들은 숭어(Mugil cephalus) 등 반염수9을 회로 먹었다고 하며 이들이 감염원일 것으로 추측되었다.

• Natural Product Sciences
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• 제15권3호
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• pp.115-120
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• 2009

Woohwangcheongsimwon (WHCSW) is a traditional oriental medicinal fomula which has been clinically used for treating strokes, palpitation, loss of consciousness and anxiety. The purpose of this study was to characterize the putative anxiolytic properties of WHCSW using an elevated plus-maze (EPM) and hole-board test. Control mice were orally treated with an equal volume of vehicle (10% Tween 80 solution), and positive control mice were treated with diazepam (1 mg/kg, i.p.). In the EPM test, WHCSW significantly increased the percentage of time-spent in the open arms (200 mg/kg, P < 0.05) and the percentage of open arm entries (200 and 400 mg/kg, P < 0.05). WHCSW also significantly increased the number of head-dips in the hole-board test (200 mg/kg, P < 0.05). In addition, the anxiolytic properties of WHCSW examined in the EPM test were inhibited by flumazenil (10 mg/kg, i.p.), a GABA$_A$ antagonist. However, no changes in spontaneous locomotor activity or myorelaxant effects were observed versus 10% Tween 80 controls. These results suggested that WHCSW is an effective anxiolytic agent, and that its anxiolytic effects are mediated via GABA$_A$ receptors.

• Journal of Chest Surgery
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• 제16권1호
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• pp.65-74
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• 1983

Fifty cases of open heart surgery were done in the Department of Thoracic and Cardiovascular Surgery, Busan National University Hospital during 16 months from July, 1981 to October, 1982. The clinical data were analyzed and summerized as follows. 1. There were 34 cases (68%) of congenital anomalies and 16 cases (32%) of acquired heart diseases. Among the congenital cases, 27 were acyanotic and 7 were cyanotic. All of the acquired heat diseases, 16 cases were valvular diseases and they had valvular replacement surgery. 2. The age distribution of the congenital anomalies ranged from 6 to 27 years with mean age of 14.2 years, and the acquired heart diseases from 18 to 44 years mean age of 27.5 years. The difference of sex distribution was no significance. 3. The clinical minifestations in acyanotic congenital anomalies were exertional dyspnea (81.5%), recurrent respiratory infection (55.6%) and palpitation (22.2%), and in cyanotic congenital anomalies were exertional dyspnea (100%), syncope(57.1%) and growth retardation(57.1%), and in acquired heart diseases were dyspnea(100%), edema (62.5%) and general weakness (62.5%) 4. During the cardiopulmonary bypass, mild to moderate core cooling was performed and added topical cooling for more accurate myocardial preservation. 5. Two kinds of cardioplegic solution used in our institute were Bretschneider solution for the first 7 cases and mixed Harmann's solution 1 L with glucose 5gm, potassium chloride 26 mEq and sodium bicarbonate 24 mEq, making 376 mosmol/L and pH 8.3 at $25^{\circ}C$, for the rest 43 cases. 6. Various kinds of postoperative complications occurred in 14 cases (28%) and showed overall mortality 12%. The mortality along with each disease was 7.4% in congenital acyanotic cases, 42.9% in congenital cyanotic cases and 6.3% in acquired valvular diseases. 7. Pre-and postoperative diagnostic incompatibility was seen in 6 cases (12%). 8. The artificial valves used in the replacement surgery were lonescu-Shiley bovine xenograft in 6 cases and Carpentier-Edwards porcine xenograft in 10 cases.

• 여성건강간호학회지
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• 제3권1호
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• pp.82-92
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• 1997

The purpose of this study was attempted to understand the substance and meaning of menopause experienced by women through informal interviews with oral consent. The informants were 6 perimenopausal women of 50-55 years old who are executing menopause. Colaizz's analytical method, a type of phenomenological analysis, was used to analyze data recorded by audiotape. One professor and a master's degree student who understand phenomenology, and the one who has a master of arts examined the validity between the meanings composed of the clusters of themes. Findings were turned out to be valid through validation process as the last step. The meaning of menopause implied both 'concept about menopause' and 'menopause as a time of change'. Menopause was mostly considered as cessation of menstruation as a physiological, natural, and normal process by aging. However, some people regarded menopause as a loss of youth and womanhood and lessening of every function of the body. Menopause as the time of changes means 'the period of' 'hormonal changes' such as change of menstruation, hot flushes, perspiration, and palpitation ; 'body function changes' of visual acuity, physical strength, sleeping, digestion, thoughts, bone and joints, skin sensibility, sexual pattern and intelligence ; 'emotional changes' such as anxiety, loneliness, gloominess, and nervousness. Menopause is a turning point on the women's life cycle accompanying various kind of changes and health problems. Therefore it is inevitable to develop strategy helping menopausal women pass through the critical successfully by adapting and coping with their critical period toward the healthy and better quality of life individually rather than putting them all into the standardized hormonal replacement protocol.

• 사상체질의학회지
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• 제19권3호
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• pp.144-155
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• 2007

1. Objectives The purpose of this study was to find the difference of ordinary and pathological symptoms according to Sasang Constitution. 2. Methods We recruited 418 subjects in the five oriental hospitals and researched normal symptoms and illness ones through a paper, who were diagnosed by the Sasang Constitution specialist in oriental hospital, who had remarkable improvement in their chief complain after Sasang Constitution medication. 3. Results 1) In ordinary symptoms, amount, speed and appetite items of Digestion are significantly different according to Sasang Constitution statistically(p<0.05). Feeling after evacuation of Feces, feeling after urination and yellow color of Urine, amount, feeling after sweat, location in hand/feet of Sweat, and in the others, Tireness in head, Drinking water, sensitivity, coldness in hand/feet, warmness in belly of Coldness/Warmness are also significantly different(p<0.05). 2) In pathological symptoms, palpitation, swelling and lack of appetite items are significantly different according to Sasang Constitution statistically(p<0.05). 3) In diseases, Hypertension and DM items are significantly different according to Sasang Constitution statistically(p<0.05). 4. Conclusions There were significantly difference items in ordinary, pathological symptoms and diseases according to Sasang Constitution.

• 대한한방부인과학회지
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• 제27권2호
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• pp.1-11
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• 2014

Objectives: The purpose of this study was to investigate the effects of Longanae Arillus water extract (LA) on the production of inflammatory mediators in RAW 264.7 cell. LA is used for forgetfulness, insomnia, palpitation symptoms in korean medicine. Methods: In order to evaluate cytotoxicity of LA, cell viability was measured. To investigate anti-inflammatory effects of LA in the lipopolysacharide (LPS)-induced RAW 264.7 cell, the concentration of nitric oxide (NO) and cytokines were measured. And when p-value is below 0.05, it is judged to have the significant difference statistically. Results: 1. LA showed no cytotoxicity. 2. LA inhibited significantly the production on NO at the concentration of 50 and $200{\mu}g/ml$. 3. LA inhibited significantly the production on interleukin (IL)-$1{\beta}$ at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 4. LA inhibited significantly the production on tumor necrosis factor (TNF)-${\alpha}$ at the concentration of 50, 100 and $200{\mu}g/ml$. 5. LA inhibited significantly the production on lipopolysaccharide-induced chemokine (LIX) at the concentration of 25, 100 and $200{\mu}g/ml$. 6. LA inhibited significantly the production on regulated on activation normal T cell expressed and secreted (RANTES) at the concentration of $200{\mu}g/ml$. Conclusions: These results suggest that LA has anti-inflammatory effect.

• Journal of Chest Surgery
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• 제10권1호
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• pp.148-155
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• 1977

The clinical findings with cardioangiography and successful surgical treatment of a 10 year old girl with double-outlet right ventricle is reported at The Dept. of Thoracic and Cardiovascular Surgery, Korea University Hospital, College of Medicine. The patient has been suffered from intermittent cyanosis, palpitation, and exertional dyspnea since 1 year after NFSD, and a holosystolic ejection murmur of grade 4 at the left 3rd intercostal space with mild cyanosis of the lips was the only physical findings at the time of this admission. Cardiac catheterization revealed ventricular septal defect with left to right shunt of 43% and right to left shunt of 10.2%. On cardioangiography from the left ventricle revealed all of the left ventricular outflow shunted into the right ventricle through the large ventricular septal defect, and the aorta originated from the infundibular chamber of the right ventricle with left, anterior sided pulmonary artery. The atria, viscera, and ventricles were normally located, and right ventricular out-flow was narrowed with infundibular hypertrophy and pulmonary valvular stenosis. Surgical correction was accomplished by closure of the ventricular septal defect in such a way that left ventricular outflow was routed via a Teflon felt prosthetic tunnel to the aorta, and pulmonary valvulotomy with infundibulectomy Was done to pass Hegar`s dilator No. 15 for reconstruction of the right ventricular outflow tract. The patient tolerated complete repair and has continued to improve over a period of three months after operation with normal school life. Details of the disease and method of repair are presented with related references.

• Journal of Chest Surgery
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• 제29권3호
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• pp.311-314
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• 1996

1985년 1월 부터 1994년 12월 까지 10년간 부산대학교 흉부외과에서는 18명의 심장 점액종 환자를 수 술하였다. 17례는 좌심방 점액 종이 었고 1례는 우심방 점액종이었다. 환자의 연령은 15세에서 62세 사이로 평균 42.6세 였고 여자가 13명 남자가 5명이었다. 술전 증상으로는 운동시 호흡곤란이 전례 에서 있었 고 심계항진이 9례, 흉통이 5례, 실신을 경험한 경우가 3례 있었으며 대부분이 전신적 무력감, 체중감소, 발열, 기침, 상복부 불쾌감 등의 다양한 동반증상이 있었다 진단은 1례의 우심방 점액 종을 제외한 나머지 17례의 좌심방 점액종에서는 심장초음파검사만으로 충분하였다 수술소견상 점액 종의 부착 부위는 난원공이 12례, 난원공 이외의 심발중격이 3례, 승모판막윤이 1례, 좌심방벽이 2례 였으며 점액종의 크기와 형태는 다양하였다. 점액종을 제거하기위한 접근은 8례에서는 우심방 절개를, 10례에서는 양심방 절 개를시행하였다. 수술로 인한 조기 및 만기 사망례는 없었고 외래 추적중재발례도 없었다. 심장점액 종의 외과적 치료는 거의 완치가 가능하며 예후가 좋은 것으로 여겨진다.

• Journal of Evidence-Based Herbal Medicine
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• 제2권2호
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• pp.17-24
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• 2009

Poria cocos has been traditionally used for the treatment of edema, scanty urine, dizziness due to retention of fluid, reduced appetite due to asthenia of spleen, loose stool, diarrhea, distraction, sudden palpitation and insomnia in East Asia. The aim of this study was to confirm whether Poria cocos wonfire whethe(PCWE) and Poria cocos ointment (PCO) have a preventive e of ter Pthe development of afire wdethe(PCWE (AD) in 2,4-Diniwhochlorobenzene (oria)-applied Balb/ wme e. Oral administration (12.5wmg/kg, 25wmg/kg) of PCWE and fire al application (O.5wmg/mouse, 1.0mg/mouse) of PCO decreased the development of AD-like skin lesions, ear swelling, spleen weight, total serum IgE. PCWE and PCO significantly also inhibited the infiltration of mast cells in the dorsal skin.

• Korean Journal of Acupuncture
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• 제23권4호
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• pp.123-133
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• 2006

Objectives : The purpose of this study was to investigate the Effect of Electro acupuncture at Kugmun $(P_4)$ and Naegwan $(P_6)$ on EKG of hypertension patients. Methods Subjects were ten patients who showed abnormal findings on EKG. They were divided into two Groups, Experiment Group and Control Group. Experiment Croup received electro acupuncture at Kugmun $(P_4)$ and Naegwan $(P_6)$ and Control Group at non acupoint. EKG was measured before and after electro acupuncture stimulation. Results : Five out of ten improved EKG findings by Kugmun $(P_4)$ and Naegwan $(P_6)$ and nine out of ten changed the pulse by Kugmun $(P_4)$ and Naegwan $(P_6)$. It showed significant change compared with Control Group that received electro acupuncture at non acupoint. In fact Kugmun $(P_4)$ and Naegwan $(P_6)$ is able to cure chest pain, hypertension, chest discomfort, palpitation, insomnia, headache, and so on. It proved that it has ability of controling heart function. Conclusions : In conclusion, electro acupuncture at Kugmun $(P_4)$ and Naegwan $(P_6)$ changed EKG findings and Pulse. Especially electro acupuncture at Kugmun $(P_4)$ and Naegwan $(P_6)$ decreased the pulse for tachycardia and increased the pulse for bradycardia. It is thought that it makes to consist vital homeostasis.