• 제목/요약/키워드: pH Sensor

검색결과 488건 처리시간 0.023초

Electrochemical Detection of Self-Assembled Viologen Modified Electrode as Mediator of Glucose Sensor

  • Lee, Dong-Yun;Choi, Won-Suk;Park, Sang-Hyun;Kwon, Young-Soo
    • Journal of Electrical Engineering and Technology
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    • 제4권1호
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    • pp.106-110
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    • 2009
  • An amperometric glucose biosensor has been developed using viologen derivatives as a charge transfer mediator between a glucose oxidase (GOD) and a gold electrode. A highly stable self-assembled monolayer (SAM) of thiol-based viologen was immobilized onto the gold electrode of a quartz crystal microbalance (QCM) and GOD was immobilized onto the viologen modified electrode. This biosensor response to glucose was evaluated amperometrically in the potential of -300mV. Upon immobilization of the glucose oxidase onto the viologen modified electrode, the biosensor showed rapid response towards glucose. Experimental conditions influencing the biosensor performance, such as pH potential, were optimized and assessed. This biosensor offered excellent electrochemical responses for glucose concentration below ${\mu}$ mol level with high sensitivity and selectivity and short response time. The levels of the RSDs (<5%) for the entire analyses reflected the highly reproducible sensor performance. A linear calibration range between the current and the glucose concentration was obtained up to $4.5{\times}10^{-4}M$. The detection limit was determined to be $3.0{\times}10^{-6}M$.

다공질 실리콘 구조를 이용한 화학 및 바이오 센서 (Porous silicon-based chemical and biosensors)

  • 김윤호;박은진;최우석;홍석인;민남기
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2005년도 제36회 하계학술대회 논문집 C
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    • pp.2410-2412
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    • 2005
  • In this study, two types of PS substrate were fabricated for sensing of chemical and biological substances. For sensing of the humidity and chemical analyzes such as $CH_3OH$ or $C_2H_5OH$, PS layers are prepared by photoelectrochemical etching of silicon wafer in aqueous hydrofluoric acid solution. To evaluate their sensitivity, we measured the resistance variation of the PS diaphragm. As the amplitude of applied voltage increases from 2 to 6Vpp at constant frequency of 5kHz, the resistance variation for humidity sensor rises from 376.3 to $784.8{\Omega}$/%RH. And the sensitivities for $CH_3OH$ and $C_2H_5OH$ were 0.068 uA/% and 0.212 uA/%, respectively. For biological sensing application, amperometric urea sensors were fabricated based on porous silicon(PS), and planar silicon(PLS) electrode substrates by the electrochemical methods. Pt thin film was sputtered on these substrates which were previously formed by electrochemical anodization. Poly (3-methylthiophene) (P3MT) were used for electron transfer matrix between urease(Urs) and the electrode phase, and Urs also was by electrochemically immobilized. Effective working area of these electrodes was determined for the first time by using $Fe(CN)_6^{3-}/Fe(CN)_6^{4-}$ redox couple in which nearly reversible cyclic voltammograms were obtained. The $i_p$ vs $v^{1/2}$ plots show that effective working electrode area of the PS-based Pt thin film electrode was 1.6 times larger than the PLS-based one and we can readily expect the enlarged surface area of PS electrode would result in increased sensitivity by ca. 1.6 times. Actually, amperometric sensitivity of the Urs/P3MT/Pt/PS electrode was ca 0.91uA/$mM{\cdot}cm^2$, and that of the Urs/P3MT/Pt/PLS electrode was ca. 0.91uA/$mM{\cdot}cm^2$ in a linear range of 1mmol/L to 100mmol/L urea concentrations

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심자도 측정용 고온초전도 SQUID magnetometer의 제작 (Fabrication of a HTS SQUID Magnetometer for Magnetocardiogram)

  • 김인선;이상길;김진목;권혁찬;이용호;박용기;박종철
    • 센서학회지
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    • 제6권4호
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    • pp.258-264
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    • 1997
  • $YBa_{2}Cu_{3}O_{7}$ 단일층 박막으로 된 직접결합형 직류 SQUID magnetometer를 설계하여 $SrTiO_{3}$기판위에 제작하였다. 검출코일은 외변 8.5 mm, 선폭은 2.6 mm로 하였으며, 조셉슨 접합의 선폭은 $3\;{\mu}m$, SQUID 인덕턴스는 50pH로 하였다. 제작된 소자의 외부 자속에 대한 전압 변조신호의 크기는 최대 $65\;{\mu}V$, 자장잡음은 1 Hz에서 약0.6 pT/$\sqrt{Hz}$ 이었다. 이 SQUID magnetometer를 사용하여 자기차폐실 내에서 심자도 파형을 측정하여 가산평균하였을 때 매우 양호한 심자도 파형을 얻을 수 있었다.

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패치형 무선 피부 온도 측정 시스템의 설계 및 구현 (Design and implement of patch type wireless skin temperature measuring system)

  • 우상효;박수영;지아 모이 우딘;원철호;이정현;박희준;이정우;홍영진;서진호;염영일;조진호
    • 센서학회지
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    • 제17권5호
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    • pp.350-360
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    • 2008
  • In every large hospital, nurses must perform simple repetitive tasks such as measuring body temperature. Such tedious work reduces nurses' motivation to provide quality medical care, which is an important element of the medical services provided by a hospital. If a device were available to measure body temperature, nurses could focus on the more important aspects of providing quality medical care to the patients. However, body temperature is generally measured from the throat, anus, tympanum or armpit, where it is difficult to affix a patch type device. In addition, general body temperature measuring points shows moving artifact error; therefore, it is not good point to continually measure the temperature. In this paper, a patch type skin temperature measuring system was developed. To appropriately measure the skin temperature, a thermal transducer was implemented with a thin (0.5 mm) temperature sensor. The system is small and thin ($H6.6{\sim}5.3{\times}L35{\times}W24\;mm$), and weighs only 5 g including a battery, case and circuit; therefore, it is small and light enough to function as a patch type device. Moreover, the system worked for 5 days. To investigate differences between the experimental and conventional thermometer, simple clinical experiments were performed with 17 volunteers, and the result showed some correlation between the implemented system and conventional thermometer (Correlation coefficient = 0.647, P<0.1).

Reactive Templated Grain Growth법에 의해 제조된 (Bi0.5Na0.5)TiO3-BaTiO3 세라믹스의 압전 특성 (Piezoelectric properties of (Bi0.5Na0.5)TiO3-BaTiO3 ceramics prepared by reactive templated grain growth method)

  • 안병국
    • 센서학회지
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    • 제16권3호
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    • pp.234-239
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    • 2007
  • Crystallographically {h00}-oriented $0.94(Bi_{0.5}Na_{0.5})TiO_{3}-0.06BaTiO_{3}$ (0.94BNT-0.06BT) ceramics was prepared by the Reactive Templated Grain Growth (RTGG) method using the $Bi_{4}Ti_{3}O_{12}$ template. The sheets prepared by tape-casting of slurries containing the templates and starting materials are cut, laminated, and pressed. Then burn-out and sintering was conducted. Also, to compare with the 0.94BNT-0.06BT ceramics prepared by the RTGG method another 0.94BNT-0.06BT ceramics was prepared by the solid-state method. In the optimum of this experiments range, the degree of orientation of the 0.94BNT-0.06BT ceramics prepared by the RTGG method was texture fraction${\approx}92%$ and the piezoelectric constant($d_{33}$) and coupling factor($k_{p}$) was obtained to $d_{33}{\approx}205{\;}pC/N$, $k_{p}{\approx}0.33%$, respectively.

심실간 공간 압력을 이용한 이동작동기형 완전이식 인공심장에서의 좌, 우심방압 추정 (Relationship between atrial pressures and the interventricular pressure in the moving actuator type total artificial heart)

  • 조영호;최원우;박성근;최재순;이종진;엄경식;김희찬;민병구
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1996년도 춘계학술대회
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    • pp.88-90
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    • 1996
  • The right and left atrial pressures are important parameters in automatic control of a total artificial heart (TAH) within normal physiological ranges. Our TAH is composed of a moving actuator, right and left ventricles and the interventricular space enclosed by a semi-rigid housing. During operation of the TAH, the jnterventpicular space's volume is changed dynamically by the difference between the ejection volume of one ventricle and the inflow volume of the other. Therefore, the changes in pressure of the interventricular space is related to both atrial pressures. We measured the interventricular pressure (IVP) waveform using a pressure sensor and attempted to indirectly estimate the changes of atrial pressures. This method has an advantage that the sensor does not contact the blood directly. Furthermore, the IVP waveforms have its zero baseline in each pump cycle, thus the pressure measurements are free from the transducer drift problems by measuring the peak pressure from these baseline values. From the In vitro experiments, we found that the IVP waveform contained several useful parameters such as negative peak, dP/dT on the initial break, the area enclosed by the profile in each stroke, which are associated with atrial pressures and the filling conditions of the ventricles. The measured atrial pressures were linearly related to the negative peak of the interventricular pressure.

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자외선 레이저를 이용한 고정밀 저항체 가공기술 개발 (Development of Trimming Technology in High-fine Resistor Using U.V. Laser)

  • 노상수;김동현;정귀상;김형표;김광호
    • 센서학회지
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    • 제11권6호
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    • pp.358-364
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    • 2002
  • 본 논문에서는 백금박막 온도센서의 $0^{\circ}C$, $100{\Omega}$ 세팅을 위해 355nm 파장을 갖는 자외선 레이저를 이용하였다. 국제적으로 온도센서의 A-class 기준오차는 $0^{\circ}C$에서 ${\pm}0.060{\Omega}$이다. 실제적으로 이 값은 $0.15^{\circ}C$이하에 해당하는 오차로 저항체 제작시 고정밀 가공 기술을 필요로 한다. 가공에 이용된 355nm DYP(Diode-Pumped YAG) 레이저는 power : 37mW, rep rate 주파수 : 200Hz 그리고 bite size : $7.5{\mu}m$에서 $1{\sim}1.5{\mu}m$ 두께의 백금박막을 가장 안전하게 가공할 수 있었으며, 가공선폭은 $10{\mu}m$ 안팎임을 확인하였다. 그리고 사진식각 공정기술을 이용하여 제작된 $2"{\times}2"$ 기판내의 96개(4 by 24) 저항체는 상온 $25^{\circ}C$에서 $79{\sim}90{\Omega}$ : 42.7%, $91{\sim}102{\Omega}$ : 57.3%의 비율로 각각 제작되어졌다. $109.73{\Omega}$를 목표 값으로 $25^{\circ}C$에서 자외선 레이저를 이용하여 가공한 결과, 82.3%가 가공오차가 ${\pm}0.03{\Omega}$이하에 들어왔으며 나머지 17.7%도 국제규격 A-Class내인 ${\pm}0.06{\Omega}$내에 포함되었다.

특발성 파킨슨병 환자의 하지 완서증 정량화를 위한 발 두드리기 동작의 각속도 분석 (Analysis of Angular Velocity during Toe Tapping for the Quantification of the Lower Limb Bradykinesia in Patients with Idiopathic Parkinson's Disease)

  • 김지원;권유리;엄광문;김형식;이정한;권도영;고성범;박병규;권대규
    • 전기학회논문지
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    • 제59권11호
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    • pp.2114-2118
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    • 2010
  • The purpose of this study was to analyze bradykinesia of toe tapping movement in patients with Parkinson's disease (PD) as compared to those of normal subjects. 39 PD patients (age: $65.5{\pm}11.2$ yrs, H&Y stage:$2.3{\pm}0.5$), 14 eldelry subjects with comparable mean age ($65.0{\pm}3.9$ yrs) and 17 healthy young subjects ($24.1{\pm}2.1$ yrs) participated in this study. Angular velocity during repetitive toe tapping movement was measured in both feet using a gyro sensor system. Suggested quantitative measures of bradykinesia were root-mean-squared (RMS) angular velocity, RMS angle, peak power and total power which were derived from the angular velocity signal. ANOVA showed that all measures were significantly different among three groups (p<0.001). Subsequent post-hoc test revealed that all measures in PD patients were significantly smaller than in healthy elderly and healthy young subjects (p<0.02). All measures were significantly correlated with UPDRS scores(r=-0.689~-0.825). These results suggest that the developed system can be used as quantitative measures of the lower limb bradykinesia in PD patients.

압전 액츄에이터용 PSN-PZT 세라믹스의 압전 특성에 미치는 MnO2 첨가 효과 (Effect of MnO2 on piezoelectric properties of PSN-PZT ceramics for piezoelectric actuator applications)

  • 최정운;송건화;김한지;윤석진;유광수
    • 센서학회지
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    • 제16권2호
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    • pp.120-125
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    • 2007
  • The effect of $MnO_{2}$ as a sintering additive on the microstructures and the piezoelectric properties, especially mechanical quality factor, of 0.05 Pb$(Sb_{0.5}Nb_{0.5})O_{3}$-0.95 Pb$(Zr_{0.52}Ti_{0.48})O_{3}$ (PSN-PZT) piezoelectric ceramics was investigated. The samples were sintered at $1250^{\circ}C$ for 2 h. The crystal structure and surface morphology of the sample were examined using XRD and FE-SEM, respectively. A study on the influence of $MnO_{2}$ additives on the dielectric and piezoelectric properties showed that the $MnO_{2}$-added PSN-PZT system exhibited a high mechanical quality factor and well-situated piezoelectric properties. The optimized results of $d_{33}$ (319 pC/N), $k_{p}$ (55 %), and $Q_{m}$ (751.24) were obtained at 0.2 wt% $MnO_{2}$ added PSN-PZT piezoelectrics.

지향성 스피커용 PSN-PZT 세라믹스의 압전 특성에 미치는 CeO2 첨가 효과 (Effect of CeO2 on piezoelectric properties of PSN-PZT ceramics for a hypersonic sound speaker application)

  • 최정범;송건화;김한지;황성익;유광수
    • 센서학회지
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    • 제17권2호
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    • pp.127-132
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    • 2008
  • The effect of $CeO_2$ as a sintering additive on the microstructure and the piezoelectric property of yPb$(Sb_{0.5}Nb_{0.5})O_3$-(1-y)Pb$(Zr_{0.52}Ti_{0.48})O_3$ ($0{\leq}y{\leq}0.1$, PSN-PZT) for a hypersonic sound speaker (HSS) application was investigated. The samples were sintered at $1250^{\circ}C$ for 2 h. The crystal structure and surface morphology of the samples were examined using XRD and FE-SEM, respectively. Study on the influence of $CeO_2$ additives on the dielectric and piezoelectric properties indicated that the $CeO_2$-added PSN-PZT system had a high piezoelectric properties. The optimized results of ${\varepsilon}_r=1209$, $K_p$=52% $d_{33}$=351(pC/N) and $Q_m$=1230.16 were obtained at 0.4 wt.% $CeO_2$-added PSN-PZT.