Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Relationship between atrial pressures and the interventricular pressure in the moving actuator type total artificial heart

심실간 공간 압력을 이용한 이동작동기형 완전이식 인공심장에서의 좌, 우심방압 추정

  • Jo, Y.H. (Dept. of biomedical engineering, College of Medicine, Seoul National University) ;
  • Choi, W.W. (Dept. of biomedical engineering, College of Engineering, Seoul National University) ;
  • Park, S.K. (Dept. of biomedical engineering, College of Medicine, Seoul National University) ;
  • Choi, J.S. (Dept. of biomedical engineering, College of Engineering, Seoul National University) ;
  • Lee, J.J. (Dept. of biomedical engineering, College of Engineering, Seoul National University) ;
  • Om, K.S. (Dept. of biomedical engineering, College of Engineering, Seoul National University) ;
  • Kim, H.C. (Dept. of biomedical engineering, College of Medicine, Seoul National University) ;
  • Min, B.G. (Dept. of biomedical engineering, College of Medicine, Seoul National University)
  • 조영호 (서울대학교 의과대학 의공학 교실) ;
  • 최원우 (서울대학교 대학원 협동과정 의용생체공학) ;
  • 박성근 (서울대학교 의과대학 의공학 교실) ;
  • 최재순 (서울대학교 대학원 협동과정 의용생체공학) ;
  • 이종진 (서울대학교 대학원 협동과정 의용생체공학) ;
  • 엄경식 (서울대학교 대학원 협동과정 의용생체공학) ;
  • 김희찬 (서울대학교 의과대학 의공학 교실) ;
  • 민병구 (서울대학교 의과대학 의공학 교실)
  • Published : 1996.05.17
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Abstract

The right and left atrial pressures are important parameters in automatic control of a total artificial heart (TAH) within normal physiological ranges. Our TAH is composed of a moving actuator, right and left ventricles and the interventricular space enclosed by a semi-rigid housing. During operation of the TAH, the jnterventpicular space's volume is changed dynamically by the difference between the ejection volume of one ventricle and the inflow volume of the other. Therefore, the changes in pressure of the interventricular space is related to both atrial pressures. We measured the interventricular pressure (IVP) waveform using a pressure sensor and attempted to indirectly estimate the changes of atrial pressures. This method has an advantage that the sensor does not contact the blood directly. Furthermore, the IVP waveforms have its zero baseline in each pump cycle, thus the pressure measurements are free from the transducer drift problems by measuring the peak pressure from these baseline values. From the In vitro experiments, we found that the IVP waveform contained several useful parameters such as negative peak, dP/dT on the initial break, the area enclosed by the profile in each stroke, which are associated with atrial pressures and the filling conditions of the ventricles. The measured atrial pressures were linearly related to the negative peak of the interventricular pressure.

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