• Title/Summary/Keyword: p67

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Notes on Newly Recorded Insect Pest, Bradysia agrestis Sasakawa (Diptera : Sciaridae ) Damaged to Pinus spp. Seedling (소나무류(類) 묘목(苗木) 가해(加害) 신(新) 해충(害蟲) 작은뿌리파리 Bradysia agrestis Sasakawa (Dipatera : Sciaridae)에 관한 연구(硏究))

  • Lee, Sang Myeong;Jeoung, Yung Jin;Kim, Hyeong Hwan;Park, Chung Gyoo;Choo, Ho Yul;Lee, Heung Su;Lee, Chong Kyu
    • Journal of Korean Society of Forest Science
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    • v.90 no.4
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    • pp.543-547
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    • 2001
  • An fungus gnat, Bradysia agrestis in the family Sciaridae was collected from Pinus spp. seedlings. This pest is a newly recorded insect from P. thunbergii, P. rigida, P. rigitaeda, and P. densiflora seedling. Brief morphological characters, damage symptom, host plants associated with the B. agrestis were recored. Significant variation in damaged of Pinus spp. seedling was attributed to differences between pine species(P. thunbergii : 15.4-20.0%, P. rigida : 23.1-48.8%, and P. rigitaeda : 13.8-67.5%, respectively) and sowing times(May : P. densiflora, 0%; P. rigida, 0%, July : P. densiflora, 20.0%; P. rigida, 49.4%, respectively).

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Systematic and Evolutionary Study on the Genus Parus(Passeriformes : Paridae) in Korea (한국산 박새속(참새목, 박새과) 조류의 계통진화)

  • 박병상;현재범;양서영
    • Animal Systematics, Evolution and Diversity
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    • v.6 no.1
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    • pp.17-28
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    • 1990
  • Electrophoretic methods were used to examine the degree of genic variation and genetic relatedness in 11 populations representing 6 species and subspecies of the genus Parus in Korea. The average degree of genic variation of 3 subspecies of P. major was =1.2, =24.4% , D=0.042, and G=0.058, whereas the rest of the species showed slightly lower degree of genic variation than P. major. Genetic relatedness between subspecies and species in the genus Parus showed similar to those reported at comparable taxnonomic levels in other birds. But it appears to be considerably less than that of non avian taxa. Genetic relatedness between 3 subspecies of P.major and P. varius varius was closely related(=0.80), whereas between P.palustrius hellmayri and P.ater amurensis was relatively remote (=0.67). The presumed divergent times of P.palustrius hellmayri, P, ater amurensis , and P. varius varius were about 1.8, 1.6, and 1.0million years before present respectively, and 3 subspecies of P. major were recently differentiated about 100 thousands years before present.

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Synthetic Lethal Mutations with spmex67 of Schizosaccharomyces pombe in the Mediation of mRNA Export

  • Yoon, Jin-Ho
    • Journal of Microbiology
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    • v.41 no.2
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    • pp.115-120
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    • 2003
  • Mex67p/Tap are evolutionally conserved mRNA export factors. To identify mutations in genes that are functionally linked to mex67 with respect to mRNA export, we used a synthetic lethal genetic screen in Schizosaccharomyces pombe. Three synthetic lethal mutants were isolated and mutations in these mutants defined separate complementation groups. These mutants exhibited the accumulation of poly A$\^$+/ RNA in the nucleus, with a decrease in the cytoplasm under synthetically lethal conditions, suggesting that the mutations cause an mRNA nuclear export defect. In addition, the S. pombe genes that were found to be involved in mRNA export did not suppress the synthetic lethality of these mutants. These results indicate that the isolated mutants contain mutations in new genes, which are involved in mRNA export from the nucleus.

Apoptosis and Cell Proliferation in Gastric Adenoma and Adenocarcinoma (위샘종과 위샘암종에서의 세포자멸사와 세포증식)

  • Lee, Dong-Soo;Kang, Sang-Bum;Lee, Seung-Woo;Nam, Soon-Woo;Yoo, Young-Kyung;Han, Sok-Won
    • Journal of Gastric Cancer
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    • v.6 no.2
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    • pp.91-96
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    • 2006
  • Purpose: Cancer is a genetic disease caused by alterations in key regulators of cell growth and cell turnover, We investigated apoptotic cell death and cell proliferation in gastric adenomas and adenocarcinomas. Materials and Methods: The TdT-mediated dUTP-biotin nick end labelling (TUNEL) method and immunohistochemistry for Ki-67 were peformed, using paraffin-embedded tissues of 41 gastric adenomas and 100 gastric adenocarcinomas. These results were compared with histopathologic parameters. Results: The Ki-67 labelling index was higher in adenocarcinomas than in adenomas and the apoptotic index was higher in adenomas than in adenocarcinomas. There were no significant difference between the apoptotic index/Ki-67 labelling index and clinicopathological parameters. Conclusion: We propose that cell proliferation is more closely associated with gastric adenocarcinomas than apoptosis is, but that neither has any clinical significance as a prognostic factor in gastric adenocarcinomas. (J Korean Gastric Cancer Assoc 2006;6:91-96)

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IL-35 Over-expression is Associated with Genesis of Gastric Cancer

  • Fan, Yong-Gang;Zhai, Jing-Ming;Wang, Wei;Feng, Bing;Yao, Guo-Liang;An, Yan-Hui;Zeng, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2845-2849
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    • 2015
  • Overexpression of interleukin (IL)-35 has been found in a variety of malignancies, but the expression status in gastric cancer has yet to be elucidated clearly. In the present study, positive expression of EBI3 and p35 was 63.3% and 70.0% of cases, respectively. EBI3 expression was strongly related with larger tumor size and invasion depth (P<0.05). Similarly, expression of p35 was also correlated with larger tumor size (P<0.05). These results indicate that IL-35 might be involved in growth of gastric cancer. Interestingly, EBI3 and p35 expressions were positive correlated with Ki-67 expression. Moreover, EBI3 immunoreactivity was associated with Bcl-2 staining. Our data suggest IL-35 is correlated with genesis of gastric cancer by regulating growth and apoptosis.

The Relationship between Sensory Processing Abilities and Gross and Fine Motor Capabilities of Children with Cerebral Palsy

  • Park, Myoung-Ok
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.2
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    • pp.67-74
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    • 2017
  • PURPOSE: The purpose of this study was to investigate the difference and relationship between sensory processing abilities, gross motor and fine motor capabilities in children with cerebral palsy. METHODS: 104 children with cerebral palsy participated in the study. Sensory processing abilities of the subjects were measured by Short Sensory Profile (SSP). Gross and fine motor abilities were each measured using the Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS), respectively. RESULTS: There were significant correlations between SSP level and GMFCS (R=.72, p<.00) or MACS (R=.77, p<.00) levels. Significant differences were showed each gross motor (p=.01) and fine motor level (p=.00) among sensory processing level of children. In addition, sub-items of sensory processing as Tactile sensitivity, Movement sensitivity, Auditory filtering and Low energy/Weak were significantly were showed significant correlations gross motor and fine motor level (p=.01). Also, multiple regression result was showed that as MACS level and GMFCS level were higher, the SSP total score was higher all of participants (adjusted $R^2=.62$). CONCLUSION: Sensory processing abilities of children with cerebral palsy were related with gross motor and fine motor capabilities. Also gross motor and fine motor capabilities are as higher, the sensory processing skill was well of cerebral palsy.

The Slope Stability Establishment with P.C. Anchoring Method (P.C. Anchoring 공법을 활용한 사면안정대책)

  • 박철숙;손재호;인영길;장두희
    • Proceedings of the KSEG Conference
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    • 2002.04a
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    • pp.61-73
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    • 2002
  • Daegok dam is Concrete Face Rockfill Dam(C.F.R.D) of which 52m height, 190m length, that construction in beneath 306, Chanjeon-Ri, Dudong-Myeon, Ulju-Gun, Ulsan Metrocity. Left slope excavation of spillway have related to Daegok dam construction are developing crack in Sta. No. 1~2, EL. 134~137m after 67.0mm rainfall from 2000. 7. 23. 13:00 to 7. 24. 04:00. Surface geological survey and slope stability investigation with stereographic projection method in order of slope stability establishment. Partial supplement excavation and SSL. P. C. Anchoring method is able to pre-stressing are think about unstable element after excavation. This slope stability establishment is very successfully completion.

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Model-based predictions for nuclear excitation functions of neutron-induced reactions on 64,66-68Zn targets

  • Yigit, M.;Kara, A.
    • Nuclear Engineering and Technology
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    • v.49 no.5
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    • pp.996-1005
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    • 2017
  • In this paper, nuclear data for cross sections of the $^{64}Zn(n,2n)^{63}Zn$, $^{64}Zn(n,3n)^{62}Zn$, $^{64}Zn(n,p)^{64}Cu$, $^{66}Zn(n,2n)^{65}Zn$, $^{66}Zn(n,p)^{66}Cu$, $^{67}Zn(n,p)^{67}Cu$, $^{68}Zn(n,p)^{68}Cu$, and $^{68}Zn(n,{\alpha})^{65}Ni$ reactions were studied for neutron energies up to 40 MeV. In the nuclear model calculations, TALYS 1.6, ALICE/ASH, and EMPIRE 3.2 codes were used. Furthermore, the nuclear data for the (n,2n) and (n,p) reaction channels were also calculated using various cross-section systematics at energies around 14-15 MeV. The code calculations were analyzed and obtained using the different level densities in the exciton model and the geometry-dependent hybrid model. The results obtained from the excitation function calculations are discussed and compared with literature experimental data, ENDF/B-VII.1, and the TENDL-2015 evaluated data.

P53 Overexpression and Outcome of Radiation Therapy in Head & Neck Cancers (두경부종양 환자에서 p53의 과발현과 방사선치료결과)

  • Kim In Ah;Choi Ihl Bhong;Kang Ki Mun;Jang Ji Young;Kim Kyung Mi;Park Kyung Shin;Young Shin Kim;Kang Chang Suk;Cho Seung Ho;Kim Hyung Tae
    • Radiation Oncology Journal
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    • v.17 no.1
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    • pp.1-8
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    • 1999
  • Purpose : Experimental studies have implicated the wild type p53 In cellular response to radiation. Whether altered p53 function can lead to changes in clinical radiocurability remains an area of ongoing study. This study was performed to investigate whether any correlation between change of p53 and outcome of curative radiation therapy in patients with head and neck cancels. Methods : Immunohistochemical analysis with a mouse monoclonal antibody (DO-7) specific for human p53 was used to detect to overexpression of protein in formalin fixed, paraffin-embedded tumor sample from 55 head and neck cancer patients treated with curative radiation therapy (median dose of 7020 cGy) from February 1988 to March 1996 at 51. Mary's Hospital. Overexpression of p53 was correlated with locoregional control and survival using Kaplan-Meier method. A Cox regression multi-variate analysis was peformed that included all clinical variables and status of p53 expression. Results : Thirty-seven (67.2$\%$) patients showed overexpression of p53 by immunohistochemical staining in their tumor. One hundred percent of oral cavity, 70$\%$ of laryngeal, 66.7$\%$ of oropharyngeal, 66.7$\%$ of hypopharyngeal cancer showed p53 overexpression (P=0.05). The status of p53 had significant relationship with stage of disease (P=0.03) and history of smoking (P=0.001). The overexpression of p53 was not predictive of response rate to radiation therapy. The locoregional control was not significantly affected by p53 status. Overexpression of p53 didn't have any prognostic implication for disease free survival and overall survival. Primary site and stage of disease were significant prognostic factors for survival. Conclusions : The p53 overexpression as detected by immunohistochemical staining had significant correlation with stage, primary site of disease and smoking habit of patients. The p53 overexpression didn't have any predictive value for outcome of curative radiation therapy in a group of head and neck cancers.

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Suitability/Unsuitability of Cell Proliferation as an Indicator of Malignant Potential in Oral Lichen Planus: an Immunohistochemical Study

  • Zargaran, Massoumeh;Jamshidi, Shokoofeh;Eshghyar, Nosratollah;Moghimbeigi, Abbas
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6979-6983
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    • 2013
  • Background: Oral lichen planus (OLP) is categorized as premalignant lesion although its malignant potential is a matter of controversy. The objective of this study was to investigate Ki67 expression in OLP, oral epithelial dysplasia and oral squamous cell carcinoma (OSCC). Materials and Methods: Expression of Ki67 was evaluated through immunohistochemistry (IHC) in groups of A (17 cases of epithelial hyperplasia), B (16 cases of OLP), C1 (10 cases of mild epithelial dysplasia), C2 (10 cases of severe epithelial dysplasia), D1 (10 cases of well-differentiated OSCC), and D2 (10 cases of poorly-differentiated OSCC). Results: There was a significant difference in Ki67 expression based on quantitative analysis among the six studied groups as well as group B compared bilaterally with groups C2, D1 and D2 (p< 0.0001). However, there was no significant difference between groups B and C1 or between groups D1 and D2 (p> 0.05). Conclusions: Based on the results of the present study it may not be possible to definitely consider malignant transformation potential for OLP. However, expression of Ki67 was significantly higher in OLP than that of epithelial hyperplasia with no significant difference from that of mild epithelial dysplasia. This should be considered by clinicians to carefully and regularly follow up OLP lesions to detect potential subtle changes at an early stage.