• 산업융합연구
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• 제20권12호
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• pp.213-217
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• 2022

본 연구의 목적은 한국인 대상의 국민건강영양조사(2018년) 자료 중 30세 이상의 인구를 대상으로 나이, 신체활동 (걷기, 근력운동), 주관적 체형 인식, 체중의 변화가 주관적 건강 상태와의 관계를 알아보고자 하였다. 본 연구의 대상과 연구방법은 제7기 3차년도 국민건강영양조사 (2018년)를 이용한 이차분석연구이다. 나이, 1주일간 걷기 일수, 1주일간 근력운동 일수, 주관적 건강 상태, 주관적 체형 인식, 그리고 1년 동안 체중 변화 유무를 변수로 이용하여 주관적 건강 상태와의 상관성 분석을 SPSS를 활용하여 통계적 유의성 있는 결과를 활용하였다(p<.01). 7일(매일) 걷기를 한다는 응답율은 30-45세는 21.9%, 50-64세는 27.2% 그리고 65세 이상은 26.6%이며, 5일 근력운동을 한다는 응답율은 30-45세는 3.6%, 50-64세는 8.4% 그리고 65세 이상은 7.9%이다(p<.001). 주관적 건강 상태는 나이 (.091), 1주일간 걷기일수(.739), 1주일간 근력운동 일수 (.530), 주관적 체형인지(.256), 1년간 체중 변화(.303)에 대해서는 양의 상관관계가 있었다(p<.01). 본 연구에서는 주관적 건강 상태는 '나쁨'이라고 응답한 연령대는 65세 이상이 21.4%로 가장 높았으며, 그 다음으로는 50-64세는 15.7%, 30-45세는 11.0% 순으로 나타났다. 이는 걷기, 근력운동을 함으로써 주관적 건강 상태가 좋아질 것으로 기대할 수 있었다. 이러한 결과를 토대로 연령에 따른 개인의 주관적 건강 상태 향상을 위한 건강 관련 프로그램을 마련하는데 기초자료로 제공하고자 한다.

• 식물조직배양학회지
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• 제22권6호
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• pp.307-310
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• 1995

Pelargonium aridum과 P. zonale의 자엽과 유식물의 절편체를 2 mg/L NAA와 0.2 mg/L BA를 첨가한 MS배지에서 배양하였을 때 캘러스를 형성하였다. 이들 캘러스는 동일배지에서 계대배양양하였다. 계대배양된 캘러스는 P. aridum의 경우 0.1∼l mg/L NAA와 0.25∼2 mg/L BA에서, P. zonale의 경우 0.1∼0.5 mg/L NAA와 1∼2 mg/L BA를 첨가한 MS 배지에 옮겨주었을 때 가장 많은 shoot를 형성하였다(P. aridum은 explant당 0.78개, P.zonale은 0.65개). 대부분의 shoot은 1/2 MS기본배지에서 배양하였을 때 발근하였다. 이들 재분화 개체들은 화분으로 옮겨진 추 온실에서 발육하여 개화하였다

• 한국미생물·생명공학회지
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• 제11권1호
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• pp.15-21
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• 1983

전보에서 분리 동정한 Y-33 균주의 $\beta$-galactosise 효소생산조건을 검토하고 효소를 정제하여 정제효소의 성질을 조사한 결과는 다음과 같다. 1. 효소생산을 위한 최적초발 pH는 7.0이었고 최적온도는 $65^{\circ}C$이었다. 2. 효소는 lactose와 galactose에 의하여 유도되어졌으며 세포내효소이었다. 3. 조효소액을 1차 DEAE-cellulose, 2차 DEAE-cellulose column chromatography 및 Sephadex G-150로 gel filtration하여 정제도가 28.3배, 수율이 15.2%의 정제효소를 얻었다. 4. 정제효소는 polyacrylamide gel 전기 영동에 의하여 순도가 검정되었다. 5. 정제효소의 유당가수분해를 위한 최적작용 온도는 $65^{\circ}C$. pH는 6.5이었다.

• 지역사회간호학회지
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• 제13권2호
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• pp.343-353
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• 2002

Objectives: The aim of this study was to explore nursing students' attitudes towards sexually active elderly, and to compare their attitudes with those of non-nursing students. Methods: Study subjects consisted of 118 nursing students, and 134 non-nursing students, recruited from two universities. The data were collected from September to November 2001. Vignettes, which presented hypothetical situations of sexual activities of the elderly (65 years of age, 80 years of age/sexual activity mentioned. non-mentioned), were provided as a research method, as well as the use of a structured questionnaire. Vignettes showed the hypothetical situations by male elder's sexual activity and their age. Respondents were asked to address their thoughts in the questionnaire. Results: 1. Nursing students showed more favorable attitudes toward the elderly than non-nursing students, regardless of the presence of sexual activity of the elderly. 2. No significant difference was found in nursing students' attitudes toward the elderly aged 65 and 80 years, between those who were sexually active and those who were not. These results were the same in non-nursing students. 3. Nursing students showed more favorable attitudes toward the sexually active elders aged 65 years (5.6 1.43), than toward sexually active elders aged 80 years (4.89 1.55). This result was also the same in non-nursing students. 4. The variables significantly affecting attitudes toward the sexually active elderly in nursing students were familiarity with old persons (p=. 02), presence of living grandparents (p=. 05), and the experience of caring for old people (p=. 01). However, in non-nursing students, familiarity with old people was the only significant variable that affected their attitudes toward the sexually active elderly. 5. In nursing students, one variable to predict attitudes toward the sexually active elderly was the experience of caring for old people (p=. 03), accounting for 10% of the total variance. In non-nursing students, familiarity with old people was the only variable to attitudes toward the sexually active elderly (p=. 03), accounting for 3% of the variance for attitude. In both student groups, the variables that predicted attitudes toward the sexually active elderly included college major (p=. 03), school year (p=. 01), familiarity with old people (p=. 02), accounting for 12% of the variance for attitude by these variables. conclusion: Nursing students showed more favorable attitudes toward the sexual activity of elders 65 years of age or over, than non-nursing students. However, both the nursing and non-nursing students showed negative attitudes toward the elderly who were 80 years of age when compared with those 65 years of age. There should be a consideration in nursing education curriculums that university students may have negative attitudes towards sexual activity of the elderly over 80 years of age.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XII)
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• pp.611-614
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• 2003

p-KG03의 고유점도는 65.22 및 50.75 $d{\ell}/g$ 이며, 사슬강도성은 0.170이였고, 특성화 농도는 0.114 g/l이었다. p-KG03은 non-Newtonic fluid로 Power-Low Model에 의한 pseudoplastic한 물성을 갖으며, 유체성으로 p-KG03 1%의 constancy index (K)는 2,172 cp, flow behavior index (n)는 0.52이었다. 특히 pH, 염 및 열에 안정하며 기존 다당류와의 혼합이용 가능성이 있을 것으로 생각된다.

• 대한방사선치료학회지
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• 제6권1호
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• pp.154-170
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• 1994

The Purpose of this study was to determine the degree and contents composing the qualify of life and to analyze the relationships among the demographic characteristics, the degree of pain and the quality of life of the cancer patients experiencing a radiation therapy. The subjects for this study were 110 out-patients experiencing a radation therapy at C University Hospital in K-city, from April to October, 1992. The data were obtained using a convenience sampling technique. The tool of this study was the quality of life scale developed by Ro, You-Ja and the data were analyzed using a SAS program for percentages, mean & standard deviation. ANOVA and Scheffe test. The results were as follows : 1. the average total score of the quality of life of the subjects was 139.65(minimum score 121-maximum score 164), item mean score grange 1-5) was 2.97. For each factor in the quality of life scale, the mean scores (range 1-5) were 3.29 in emotional state, 3.14 in relationship with neighbors. 3.04 in physical state and function. 2.92 in self-esteem, 2.81 in economic life and 2.65 in relationship with family. 2. The incidence of physical symptoms was seen fatigue ($84.5\%$). anorexia ($65.5\%$) and weight loss ($47.3\%$) in order. The 50.9 percentage of the subjects complained of moderate or severe pain. 3. The results of the analysis of the relationships between the demographic variables and the quality of life were as follows : Gender (F=8.45, P=0.0044), age (F=6.29, P=0.0001). educational level (F=5.67, P=0.0046), marital status (F=6.82. P=0.0016), occupation (F=2.86, P=0.009), monthly income (F=6.90, P=0.0003), family living together (F=3.95, P=0.0494) and person paying a medical fee (F=5.14, P=0.0023). 4. The relationship between the degree of pain and the quality of life was significant difference (F=3.12, P=0.0482).

• Clinical and Experimental Emergency Medicine
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• 제5권4호
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• pp.249-255
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• 2018

Objective As aging progresses, clinical characteristics of elderly patients in the emergency department (ED) vary by age. We aimed to study differences among elderly patients in the ED by age group. Methods For 2 years, patients aged 65 and older were enrolled in the study and classified into three groups: youngest-old, ages 65 to 74 years; middle-old, 75 to 84 years; and oldest-old, ${\geq}85years$. Participants' sex, reason for ED visit, transfer from another hospital, results of treatment, type of admission, admission department and length of stay were recorded. Results During the study period, a total 64,287 patients visited the ED; 11,236 (17.5%) were aged 65 and older, of whom 14.4% were 85 and older. With increased age, the female ratio (51.5% vs. 54.9% vs. 69.1%, P<0.001), medical causes (79.5% vs. 81.3% vs. 81.7%, P=0.045), and admission rate (35.3% vs. 42.8% vs. 48.5%, P<0.001) increased. Admissions to internal medicine (57.5% vs. 59.3% vs. 64.7%, P<0.001) and orthopedic surgery (8.5% vs. 11.6% vs. 13.8%, P<0.001) also increased. The ratio of admission to intensive care unit showed no statistical significance (P=0.545). Patients over age 85 years had longer stays in the ED (330.9 vs. 378.9 vs. 407.2 minutes, P<0.001), were discharged home less (84.4% vs. 78.9% vs. 71.5%, P<0.001), and died more frequently (6.3% vs. 10.4% vs. 13.0%, P<0.001). Conclusion With increased age, the proportion of female patients and medical causes increased. Rates of admission and death increased with age and older patients had longer ED and hospital stays.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.9039-9043
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• 2014

There is a continuing need for innovative alternative therapies for liver cancer. DNA vaccines for hormone/growth factor immune deprivation represent a feasible and attractive approach for cancer treatment. We reported a preventive effect of a DNA vaccine based on six copies of the B cell epitope GRP18-27 with optimized adjuvants against H22 hepatocarcinoma. Vaccination with pCR3.1-VS-HSP65-TP-GRP6-M2 (vaccine) elicited much higher level of anti-GRP antibodies and proved efficacious in preventing growth of transplanted hepatocarcinoma cells. The tumor size and weight were significantly lower (p<0.05) in the vaccine subgroup than in the control pCR3.1-VS-TP-HSP65-TP-GRP6, pCR3.1-VS-TP-HSP65-TP-M2 or saline subgroups. In addition, significant reduction of tumor-induced angiogenesis associated with intradermal tumors of H22 cells was observed. These potent effects may open ways towards the development of new immunotherapeutic approaches in the treatment of liver cancer.

• The Journal of Korean Physical Therapy
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• 제31권4호
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• pp.248-253
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• 2019

Purpose: To improve pulmonary function and decrease in balance ability with increasing forward head position and vertebral curvature, we applied Figure-8 brace to confirm the immediate effect on vital capacity and balance and to see if it is applicable. Methods: A total of 34 elderly women aged 65 or older and young women in their 20s with FHP were screened to measure vital capacity, measuring the forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), and measuring the foot pressure to see the change in balance. For statistical analysis, the difference between pre and post values was compared using pared t-test. Results: As a result of vital capacity measurements, there was no significant difference between FEV1 and FVC for women over 65 years old (p>0.05). Young women in their 20s had no significant difference in FEV1 (p>0.05), and FVC had significant differences (p<0.05). In measuring foot pressure to measure balance, both women aged 65 and above and young women in their 20s had a significant decrease in anterior foot pressure, and a significant increase in posterior foot pressure (p<0.05). Conclusion: The results of this study did not positively affect the vital capacity of elderly women with FHP. However, the significant increase in vital capacity of young women in their 20s suggests that contraction of the abdominal muscle is necessary during forced expiration. Therefore, it is believed that proper application and therapeutic interventions should be combined when applying Figure-8 brace.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4693-4697
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• 2016

Aim: The objective of this study is to investigate prognostic factors affecting survival of patients undergoing concurrent or sequential chemoradiotherapy (CRT) for stage III non-small-cell lung cancer (NSCL). Methods and materials: We retrospectively reviewed the clinical records of 148 patients with advanced, inoperable stage III NSCLC, who were treated between 2007 and 2015. Results: The median survival was found to be 19 months and 3-year overall survival was 27%. Age (<65 vs ${\geq}65years$, p=0.026), stage (IIIA vs IIIB, p=0.033), dose of radiotherapy (RT) (<60 vs ${\geq}60Gy$, p=0.024) and treatment method (sequential chemotherapy+RT vs concurrent CRT, p=0.023) were found to be factors affecting survival in univariate analyses. Gender, histological subtype, weight loss during CRT, performance status, induction/consolidation chemotherapy and presence of comorbidities did not affect survival (p>0.050). Conclusion: Young age, stage IIIA, radiotherapy dose and concurrent chemoradiotherapy may positively affect survival in stage III NSCL cases.