• Journal of Nutrition and Health
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• v.48 no.1
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• pp.113-121
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• 2015

Purpose: The purpose of this study was to investigate satisfaction with and perception of the school meal service according to middle school students and dieticians/dietetic teachers in Gwangju area who experienced change to the free meal service and the main contents were as follows. Methods: The research subjects were 197 students (99 boys and 98 girls) and 42 dieticians/dietetic teachers were recruited. Results: Compared to the free meal service before, satisfaction of students was high (53.8%), and 69.9% of students said there was no change in the school meals, however a significant difference was observed between gender. Overall 80.2% of middle school students said that there was no change in menu, 70.6% were no change in the frequency of food with high preference, and 64.0% were no change in leftover of meals. 85.7% of dieticians/dietetic teachers said that there was no change in the student's satisfaction according to the conversion of free meal services; 59.5% of dieticians/dietetic teachers said that there was no change in the frequency of foods with high preference, the variety of vegetables was increased in the qualitative change item of food materials, and 95% of them were not aware of change in the amount of students' leftover foods. Dieticians/dietetic teachers had limitations in selecting menus with purchase and costs of food materials (26.2%) by conversion of the free meal service and their priority considered was the food cost (45.2%) when they selected menus. Change in feeding affairs was office work management (26.2%) and recipe research and development (19.0%). Conclusion: With the results of this study, the satisfaction with the school meal service was not changed in the awareness of students and dieticians/dietetic teachers. Therefore further study is needed to determine the middle school's satisfaction with school meals based on a variety of factors including the environmental food meal services.

• Clinical and Experimental Pediatrics
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• v.53 no.4
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• pp.592-597
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• 2010

Hyperimmunoglobulin E syndrome (HIES) is a rare immunodeficiency disease which is characterized by high serum IgE levels, eczema, and recurrent infections. Herein we present the case of a patient with HIES associated with STAT3 gene ($stat3$) mutation. A 16 year-old girl was admitted to our hospital due to hemoptysis caused by pneumonia with bronchiectasis. She had a history of recurrent skin and respiratory tract infections, such as pneumonia caused by MRSA (methicillin-resistant $Staphylococcus$ $aureus$) and $Pseudomonas$ $aeruginosa$. On physical examination, a broad round shaped nose, oral thrush, and chronic eczematous skin rash over her whole body were found. Laboratory data showed an elevated eosinophil count ($750/{\mu}L$) and total IgE level (5,001 U/mL). The patient's National Institutes of Health (NIH) score for HIES was 44. Direct sequencing of the STAT3 gene revealed that the patient was heterozygous for a missense mutation in the DNA binding domain of the STAT3 protein (c.1144C>T, p. Arg382Trp). HIES should be suspected in patients with recurrent infections and can be confirmed by clinical scoring and genetic analysis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.6008-6014
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• 2013

This study aimed to understand seasonal variation of physico-chemical factors and biomass of size-fractionated phytoplankton at Ulsan seaport during the period from February 2007 to November 2009. Water temperature, salinity, dissolved oxygen (DO), pH, chemical oxygen demand (COD) and total suspended solid (TSS) varied in the range of 8.94-$24.26^{\circ}C$, 25.06-34.54 psu, 4.30-10.73 mg/L, 7.97-8.53, 0.66-40.70 mg/L and 57.4-103.3 mg/L, respectively. These factors showed no clear spatial variation unlike spatial pattern of inorganic nutrients and total chlorophyll-a (chl-a) concentration as biomass. Concentration of phosphate, nitrate and silicate ranged from 0.01 to 3.03 ${\mu}M$, 0.05 to 21.62 ${\mu}M$, and 0.01 to 27.82 ${\mu}M$, respectively, with 2 times higher concentration at inner stations than that at outer stations during the study period. Within the range of total chl-a concentration (0.36-7.11 ${\mu}gL^{-1}$), higher concentration (avg. 1.88 ${\mu}gL^{-1}$) of total chl-a were observed at inner stations compared to that (avg. 0.90 ${\mu}gL^{-1}$) at outer stations. Micro-sized phytoplankton dominated total biomass of phytoplankton in spring (34.0-81.2%), summer (35.1-65.6%) and winter (3.9-62.0%). Nano- and pico-sized phytoplankton contributed 58.2-74.5% and 22.4-38.2% to total biomass of phytoplankton in autumn, respectively. However, contribution in biomass of size-fractionated phytoplankton to total phytoplankton biomass showed no clear difference between inner and outer stations. Consequently, these results indicated that spatio-temporal distribution of phytoplankton biomass at Ulsan seaport was dominated by micro-phytoplankton (avg. 52.3%) during the study period except autumn, which was closely dependent on the concentration of inorganic nutrients (p<0.05).

• KSBB Journal
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• v.20 no.6
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• pp.443-446
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• 2005

Hydrogen fermentation from food waste was attempted at different hydraulic retention time(HRT, 18-42 h). A continuous reactor fed with ground, alkali-treated and diluted food waste(average VS 4.4%) exhibited stable hydrogen production during 126 days. Hydrogen production depended on HRT, resulting in the maximum values of 25.8 mL $H_2/g\;VS_{added}$, 0.36 mol $H_2/mol\;hexose_{added}$ and 0.91 L $H_2/L/d$ at HRT 30 h. n-Butyrate and isopropanol production increased with hydrogen production increased, while acetate production decreased. The fermentation efficiency ranged from 53.3 to 65.7%, which implied that hydrogen fermentation would substitute conventional acidogenesis of food waste.

• Korean Journal of Applied Biomechanics
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• v.29 no.3
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• pp.185-196
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• 2019

Objective: The aim of this study was to suggest correct and effective way of squat through biomechanical analysis variables on the change of the toe-out angle. Method: 7 high school male weightlifter (age: $17.57{\pm}0.53yrs$, height: $174.0{\pm}3.93cm$, weight: $81.0{\pm}9.17kg$, 1RM: $164.29{\pm}20.7kg$) participated in this study. Results: Angle of the hip joint at E2 was smaller than toe-out angle was in $20^{\circ}$ than in $0^{\circ}$ (p<.05). Angular velocity of the foot joint at E1 and E3 was quicker that in $10^{\circ}$ than in $30^{\circ}$ (p<.05). Anterior-posterior stability index was greater that toe-out angle was in $30^{\circ}$ than in $0^{\circ}$ (p<.05). In average iEMG of flexion phase, VM of right, left leg showed high activity at toe-out angle $30^{\circ}$. In average iEMG of flexion phase, extension phase and in peak iEMG, RF of right leg, VM and VL of left leg showed high activity at all of the toe-out angles. In average iEMG of flexion phase, extension phase and in peak iEMG, all of the muscles activity of right leg showed high in $10^{\circ}$ and low in $0^{\circ}$, $30^{\circ}$. Conclusion: It is judged that setting the toe-out angle $10^{\circ}$ in squat help to efficiently use muscles and ensure stability.

• Journal of Korean Biological Nursing Science
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• v.14 no.4
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• pp.258-267
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• 2012

Purpose: The purpose of this study was to identify the relationship between energy intake and fatigue in cancer patients receiving chemotherapy. Methods: A total of 106 subjects had participated in this study. Data were collected at a university hospital in D city from September 1st to November 10th, 2010. Energy intake including carbohydrates, protein and fat was measured by scale and analyzed using Can Pro 3.0 program. Fatigue level was measured by the Revised Piper Fatigue Scale. Data were analyzed using descriptive analysis, t-test, ANOVA and Pearson correlation coefficient with SPSS/WIN 15.0. Results: The mean calorie intake during chemotherapy was $906.53{\pm}201.28Kcal/day$ which was 45.3% of the recommended daily calorie intake. The mean of protein intake level was $43.62{\pm}11.13g/day$, and it was low compared to the recommended daily protein intake. Calories, carbohydrates, and protein levels on 3rd day after chemotherapy were significantly lower than those of 2nd day after chemotherapy (p<.001). The fatigue level during chemotherapy was $5.77{\pm}0.77$ which was moderate level of fatigue. There was a significant negative interrelation between energy intake and fatigue. Conclusion: Theses results suggested that nursing approaches to encourage dietary intake may be helpful to reduce fatigue for cancer patients receiving chemotherapy.

• Journal of Life Science
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• v.28 no.7
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• pp.778-785
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• 2018

Autophagy is a complex signaling process and has been implicated in tumor suppression and anticancer therapy resistance. Autophagy can produce tumor-suppressive effect by inducing autophagic cell death, either in collaboration with apoptosis. In this current study, we found that celecoxib (CCB), a nonsteroidal anti-inflammatory drug (NSAID) with multifaceted effects, induced autophagy including enhanced LC3 conversion (LC3-I to LC3-II) and reduced autophagy substrate protein p62 level in multidrug-resistant (MDR) cancer cells. CCB sensitized human multidrug resistant (MDR) cancer cells to the ansamycin-based HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG), a benzoquinoid ansamycin, which causes the degradation of several oncogenic and signaling proteins, by inducing autophagic cell death and apoptosis. CCB significantly augmented 17-AAG-mediated level of LC3-II/LC-I, indicating the combined effect of 17-AAG and CCB on the induction of autophagy. Autophagic degradation of mutant p53 (mutp53) and activation of caspase-3 in 17-AAG-treated MDR cells were accelerated by CCB. Inhibition of caspase-3-mediated apoptotic pathway by Z-DEVD-FMK, a caspase-3 inhibitor, did not completely block CCB-induced cell death in MCF7-MDR cells. In addition, treatment of MDR cells with Z-DEVD-FMK failed to prevent activation of autophagy by combined treatment with 17-AAG and CCB. Based on our findings, the ability of clinically used drug CCB to induce autophagy has important implications for its development as a sensitizing agent in combination with Hsp90 inhibitor of MDR cancer.

• Tuberculosis and Respiratory Diseases
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• v.53 no.1
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• pp.27-35
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• 2002

Background : The paradoxical response refers to an enlargement of old lesions or unexpected new ones during apparently adequate antituberculous therapy. This response has been reported in cases of intracranial tuberculoma, tuberculous lymphadenopathy, tuberculous pleurisy and pulmonary tuberculosis. However, there are few reports on its frequency and clinical characteristics. Materials and Methods : This study enrolled 205 patients who were treated with first line antituberculous agents for more than 6 months. We retrospectively studied 155 patients with pulmonary tuberculosis and 57 patients with pleural tuberculosis (7 patients had both) from July 1998 to March 2000. The patients were divided into the paradoxical response group and the non-paradoxical group. The clinical characteristics of the paradoxical response group and the non-paradoxical group. The clinical characteristics of the paradoxical group were investigated. Statistical analysis was done with an independent sample T-test and Chi-squared test. Results : 29 of the 205 patients(14.1%) had paradoxical response. Among the 29 patients, there were 19 pulmonary tuberculosis, 8 tuberculous pleurisy(2 patients had both). Paradoxical response appeared 32 days (mean 35 days in pulmonary tuberculosis, mean 25 days in tuberculous pleurisy) after the beginning of chemotherapy. The duration to regress less than half of initial chest lesion was 114 days in pulmonary tuberculosis and 124 days in tuberculous pleurisy, respectively. Most common clinical manifestation of paradoxical response patients was coughing in both pulmonary tuberculosis and tuberculous pleurisy. Male sex, high blood WBC count and high level of pleural fluid LDH were related with paradoxical response. Conclusion : These findings suggest that presponse usually appears 1 month and disappears within 4 months after the beginning of anti-tuberculous chemotherapy. Paradoxical response was relatively correlated with male sex, high blood WBC count and high level of pleural fluid LDH.

• The Korean Journal of Food And Nutrition
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• v.27 no.5
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• pp.817-825
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• 2014

This study was conducted to investigate the amounts of capsaicinoid and free sugar, as well as ASTA color values in three pepper cultivars grown in different regions of Korea. Pepper cultivars from ten different regions of Korea were collected in 2011 and 2012. The capsaicinoid contents of the three cultivars, Urigun, Bugang, and Muhanjilju, varied in the range of 52.53~362, 15.35~126.40, and 3.41~50.86 mg/100 g, respectively, depending on their cultivation region. Among the three cultivars, Urigun had the highest average capsaicinoid content, followed by Bugang and Muhanjilju. The free sugar contents of Urigun, Bugang, and Muhanjilju varied in the range of 18.29~35.54, 16.91~32.83, and 18.63~33.21%, respectively, depending on the region. Average free sugar contents did not vary significantly among the cultivars grown in different regions as well as in different years. The ASTA color values of Urigun, Bugang, and Muhanjilju varied in the range of 57.17~132.61, 66.23~139.49, and 85.43~133.26, respectively. ASTA color values of the three cultivars grown in 2012 were significantly higher than those grown in 2011. Variations in the amounts of capsaicinoids, free sugar contents, and ASTA color values observed in this study can be attributed to the intrinsic genetic characteristics of each cultivar or alternatively to the environmental conditions. We assume that the quantity of capsaicinoid is affected more by the genotype than the cultivation region, whereas the reverse holds for the variations in free sugar quantity and ASTA color values.

• Korean Journal of Plant Resources
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• v.25 no.5
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• pp.517-522
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• 2012

This study was conducted to investigate the morphological and anatomical characteristics of needle and the genetic diversity of Pinus pumila Regel which is a unique and the southern peripheral population in South Korea. ANOVA test showed that there were significant differences among individuals within population in all 8 needle characteristics. Average characteristics of 66 individuals were 53.59 mm in needle length, 0.78 mm in needle width, 68.98 in needle index, 0.65 mm in needle thickness, 4.56 ea. in maximum stomata row, 3.80 ea. in minimum stomata row, 8.36 ea. in total stomata row and 1.71 ea. in resin canals, respectively. Resin canal per needle of this species ranged from one to three, depending on external type. Especially, arrangement types were 69.47% in two resin canals and 30.45% in a single resin canal. A total of 78 bands was generated from 9 selected I-SSR primers. The estimates of genetic variation were 61.5% in proportion of polymorphic bands (P), 1.698 in effective number of alleles ($A_e$), 0.388 in expected heterozygosity ($H_e$) and 0.567 in Shannon's information index (S.I.), respectively.