• 한국식품영양학회지
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• 제30권1호
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• pp.41-50
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• 2017

This study developed a vegetable preference increase program that can be applied at the Center for Children's Foodservice Management (CCFM) for children in child-care facilities and kindergarten and the training performance was evaluated by 192 5-year old children. Teachers considered 'disliked food' ($3.23{\pm}0.85/out$ of 5) as the most serious nutritional problem and typical disliked food was 'vegetables' (54.2%). Based on this finding, to increase the preference for vegetables, a five-phase education program was developed. In this program, each phase was composed of activities to increase children's interest in vegetables by using each sense out of the five senses. Center dieticians had visited and conducted the program in 12 facilities. By using an illustration assessment tool, the training performance was evaluated by comparing the children's knowledge level and their preference changes in vegetables. Consequently, as examined by 10 questions on the knowledge of vegetables, trained children's (in total 192) knowledge of vegetables had considerably increased (p<0.01, p<0.001), and their preference for 15 out of the 16 vegetables, except for carrots, also showed a considerable preference increase after the training (p<0.01, p<0.001). Therefore, this program is considered to have contributed to reducing disliked vegetable eating behaviors.

• 대한치과보철학회지
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• 제45권6호
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• pp.760-768
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• 2007

Statement of problem. Conventional denture treatment for totally edentulous patients is associated with a variety of functional and psychosocial problems. The placement of implants in the anterior region of the maxilla and mandible and the fabrication of an implant-retained overdenture might solve these problems. Purpose. This study compared the marginal bone loss around the implant and evaluated the implant survival rate and complications in patients treated with overdentures retained by implants for 2 years. Material and methods. Patients who had received implant-retained overdentures using a Dolder bar at Samsung Medical Center from January 1999 to June 2005 and had participated in the annual recall programs for two years were selected for this study. A total of 18 patients and 56 $Br{\aa}ne-mark\;system^{(R)}$ implants were used, and their data were reviewed. Evaluations of the survival rate, bone quality, marginal bone loss, and complications were performed. The data on the Dolder bar length and clip length were measured. The change in marginal bone loss and the correlation between the marginal bone loss and bar length, clip length, or bone quality were investigated. Results. Implants placed in this study showed a 100% survival rate. The average annual bone loss was 1.12mm in the first year and 0.27mm in the second year in the maxilla, and 0.58mm in the first year and 0.22mm in the second year in the mandible. The marginal bone loss in the maxilla showed no significant association with those in the mandible. (P>.05). There was no significant difference in marginal bone loss around implants between the first and second year. (P>.05) There was no statistically significant relationship (P>.05) between the marginal bone loss and bone quality, clip length, or Dolder bar length. The Dolder bar length showed a high correlation with the clip length. (P<.05) Various complications were noted. Conclusion. These results confirmed the favorable outcome for patients treated with implant-retained overdentures.

• 대한약침학회지
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• 제22권3호
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• pp.154-159
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• 2019

Objectives: Toxoplasmosis is a worldwide health problem that caused by intracellular apicomplexan parasite, Toxoplasma gondii (T. gondii). Considering that the available drugs for toxoplasmosis have serious host toxicity, the aim of the current study was to survey the in vitro and in vivo anti-Toxoplasma activity of Zea mays (Z. mays) and Eryngium caucasicum (E. caucasicum) extracts. Methods: Four concentrations (5, 10, 25, and $50mg\;mL^{-1}$) of Z. mays and E. caucasicum methanolic extracts for 30, 60, 120, and 180 min were incubated with infected macrophages and then the viability of RH strain of T. gondii tachyzoites was evaluated by trypan blue staining method. Also, we evaluated the survival rate of acutely infected mice with the extracts (100 and $200mg\;kg^{-1}\;day^{-1}$) intraperitoneally for 5 days after infection with $2{\times}104$ tachyzoites of T. gondii. Results: The anti-Toxoplasma effect of the methanolic extracts were extremely significant compared to the negative control group in all exposure times (P < 0.05). The Z. mays (10, 25 and $50mg\;mL^{-1}$) killed 100% of the parasites after 180 and 120 min exposure, respectively. Also, high toxoplasmacidal activity was observed with E. caucasicum extract. Furthermore, treatment of experimentally infected mice with the Z. mays (100, $200mg\;kg^{-1}\;day^{-1}$) and E. caucasicum ($100mg\;kg^{-1}\;day^{-1}$) significantly increased their survival rate compared to untreated infected control (P < 0.05). Conclusion: These extracts are promising candidates for further medicine development on toxoplasmosis. However, further investigations are necessary to clarify effective fractions of the Z. mays and E. caucasicum extracts and the mechanisms of action.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9801-9804
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• 2014

Background: Colorectal cancer is currently the third most common cancer in Indonesia, yet colonoscopy - the most accepted mode of screening to date - is not done routinely and national data are still lacking. Objective: To determine the detection rate of colorectal cancers and adenomas in unselected patients undergoing colonoscopy for various large bowel symptoms at the Digestive Disease and GI Oncology Centre, Medistra Hospital in Jakarta, Indonesia. Materials and Methods: Colonoscopy data from January 2009 to December 2012 were reviewed. New patients referred for colonoscopy were included. Data collected were patient demographic and significant colonoscopy findings such as the presence of hemorrhoids, colonic polyps, colonic diverticula, inflammation, and tumor mass. Histopathological data were obtained for specimens taken by biopsy. Associations between categorical variables were analyzed using chi-square test, while mean differences were tested using the t-test. Results: A total of, 1659 cases were included in this study, 889 (53.6%) of them being men. Polyps or masses were found in 495 (29.8%) patients while malignancy was confirmed in 74 (4.5%). Patients with a polyp or mass were significantly older (60.2 vs 50.8 years; p<0.001; t-test) and their presence was significantly associated with male gender (35.0% vs 23.9%; prevalent ratio [PR] 1.71; 95% confidence interval [CI] 1.38-2.12; p<0.001) and age >50 years (39.6% vs 16.6%; PR 3.29; 95% CI 2.59-4.12; p<0.001). Neoplastic lesions was found in 257 (16.1%), comprising 180 (11.3%) adenomas, 10 (0.6%) in situ carcinomas, and 67 (4.2%) carcinomas. Conclusions: Polyps or masses were found in 30% of colonoscopy patients and malignancies in 16.1%. These figures do not represent the nation-wide demographic status of colorectal cancer, but may reflect a potentially increasing major health problem with colorectal cancer in Indonesia.

• 원예과학기술지
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• 제31권6호
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• pp.821-827
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• 2013

본 연구는 세 가지 원예활동이 초등학생의 주의집중력에 미치는 영향을 알아보고자 실시되었다. 경상북도 영천시 J초등학교 내 Wee Class 상담실을 이용하는 초등학생을 대상으로 실험군 10명에게는 꽃장식, 심기, 압화 등 원예활동을 실시하였고, 실험에 참여하지 않은 10명의 대조군을 두었다. 각 원예활동은 주 1회 총 3회씩 실시되었고, 주의집중력 검사지와 Harris 격자판은 원예활동 실시 1주일 전과 9회기 종료 후 대조군과 실험군을 대상으로 조사되었으며, 특히 Harris 격자판은 실험군을 대상으로만 매주 원예활동 후 실시하였다. 검사지를 이용한 주의집중력 평가 결과, 원예활동 후 정서적인 문제에서 9.2점, 관리기능상의 문제에서 7.8점, 그리고 전체 점수도 19.0점 감소하여(P < 0.05) 실험군의 주의집중력이 대조군과 비교하여 향상되었음을 알 수 있었다. Harris 격자판을 이용한 주의집중력 검사 결과, 꽃장식, 심기 및 압화 활동은 실시 전 6.00점에 비해 실시 후 각각 2.22, 2.49, 그리고 2.41점이 높아졌는데(P < 0.05), Harris 격자판 점수의 증가는 주의집중력 향상을 의미한다. 원예활동 실시 후, 꽃장식, 심기 및 압화 활동은 대조군의 7.10점에 비해 각각 1.12, 1.39, 1.31점을 증가시켰다(P < 0.05). 결론적으로 꽃장식, 심기 및 압화 등 실내 원예활동은 초등학생의 주의집중력 향상에 효과적이었다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제9권4호
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• pp.252-255
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• 2004

A pfl ldhA double mutant Escherichia coli strain NZN 111 was used to produce succinic acid by overexpressing the E. coli malic enzyme gene (sfcA). This strain, however, produced a large amount of malic acid as well as succinic acid. After the analyses of the metabolic pathways, the fumB gene encoding the anaerobic fumarase of E. coli was co-amplified to solve the problem of malic acid accumulation. A plasmid, pTrcMLFu, was constructed, which contains an artificial operon (sfcA-fumB) under the control of the inducible trc promoter. From the batch culture of recombinant E. coli NZN 111 harboring pTrcMLFu, 7 g/L of succinic acid was produced from 20 g/L of glucose, with no accumulation of malic acid. From the metabolic flux analysis the strain was found under reducing power limiting conditions by severe reorientation of metabolic fluxes.

• 한국정밀공학회지
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• 제33권6호
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• pp.469-475
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• 2016

In this work, casting processes, such as filling and solidification, were simulated in order to accurately predict volume shrinkage defects in large-sized sand gravity casting. Turbulent flow of melted materials and a difference of solidification speed can cause volume shrinkage defects. In order to solve this problem and to understand the phenomenon, a porous filter application was studied. Two different porosities of 10 and 20 p.p.i filters were introduced into the gating system, and in view of the results so far achieved, the defect was dramatically reduced by 22%, compared to that without the use of the filter.

• 정신간호학회지
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• 제27권4호
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• pp.370-379
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• 2018

Purpose: The purpose of this study was to test the mediating effect of depression on the relationship between gambling severity and cognitive distortion in Koreans with a gambling disorder. Methods: Secondary data from a comprehensive assessment of problematic gambling between 2015 and 2017 on Korea Center on Gambling Problems were used. The subjects in this study were 254 Koreans with that gambling disorder. Data were collected with self-report structured questionnaires which included individual characteristics, the Korean version of Problem Gambling Severity Index, the Center for the Epidemiologic Studies Depression, and the Gambling Related Cognitions Scale. Data were analyzed by using descriptive statistics, independent t-test, one-way ANOVA with the $Scheff{\acute{e}}$ test, Pearson's correlation coefficients, and a mediation analysis of the Baron and Kenny method with the SPSS 22.0 program. Results: Significant correlations emerged among the three variables, gambling severity, depression, and cognitive distortion. Depression exerted a partial mediating effect (${\beta}=.20$, p<.001) on the relationship between gambling severity and cognitive distortion (Sobel test: z=2.33, p=.012). Conclusion: Based on this study's findings, nursing intervention programs focused on managing gambling severity and decreasing depression are highly recommended to alleviate cognitive distortion in people with a gambling disorder.

• 디지털융복합연구
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• 제15권7호
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• pp.1-12
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• 2017

본 연구는 메타인지 강화 수업 전략이 학생들의 창의적 사고력, 비판적 사고력, 메타인지 사고 활용능력에 미치는 효과를 알아보고자 하였다. 선행 연구 자료를 참고로 하여 메타인지 활성화를 위한 자기-질문지를 제작하고, 이를 활용하여 대학생용 메타인지 강화 창의적 문제 해결력 지향 수업 전략을 개발하였다. 그리고 대학교 1학년 학생을 대상으로 개발한 수업 전략을 9주간 실시하였다. 실험 집단과 통제 집단에 창의적 문제 해결력 검사지, 영역 독립 메타인지 검사지를 사용하였으며, 각 집단의 점수 차이가 통계적으로 유의미한지 알아보기 위하여 공변량 분석(ANCOVA)을 실시하였다. 그 결과 실험 집단 학생들의 창의적 사고력과 비판적 사고력이 유의미하게 신장되었다(p<.05). 창의적 사고력의 하위 문항 중에서는 문제 인식, 가설 설정, 변인 통제에 해당하는 문항에서 긍정적인 효과를 보였으며, 비판적 사고력의 하위 문항 중에서는 문제 인식, 가설 설정에 해당하는 문항에서 긍정적인 효과가 나타났다. 또한, 영역 독립 메타인지의 활용 능력에 있어서도 유의미한 신장을 보였다(p<.05). 메타인지 강화 전략은 사고력 신장에 효과적이었으며, 융합적사고력 향상에 기여할 수 있을 것이다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2002년도 추계종합학술대회
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• pp.588-591
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• 2002

최근 클라이언트- 서버방식의 네트웍 서비스보다 P2P(Peer-to-Peer)서비스 환경이 더욱더 각광을 받고 있다. P2P는 자유로운 네트웍을 구성할 수 있고 중앙 서버 기능을 없애거나 약화시켜서 각 User 간에 참여할 수 있는 개방 네트워크이기 때문에 각 User 간에 인증에 관한 문제가 대두되고 있다. Network에 있는 어떤 사용자가 공개된 환경에 있다고 가정하면 우리는 각 User간에 허가 받은 사용자에게만 접속을 제한하기 위해선 서비스에 대한 요구를 인증해 줄 수 있기를 바란다 본 논문에서는 이를 해결하기 위해 P2P환경에서 안전하게 정보공유를 할 수 있는 메커니즘으로 kerberos인증 메커니즘을 인용하여 인증 메커니즘을 설계하고자 한다.