• 융합정보논문지
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• 제8권3호
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• pp.71-77
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• 2018

본 논문에서는 환자의 산소 민감도와 선호패턴을 고려하여 개인별 산소치료 프로파일을 지정하고, 여기에 따라 자동적으로 시간별 산소압을 조정하여 제공하는 3단 분리형 단격실 산소챔버를 설계한다. 고압산소치료는 대기압보다 높은 100% 산소를 환자에게 제공하는 방법으로 개인에 따라 기압차에 따른 귀의 통증을 호소하는 단점이 있었다. 제안 시스템은 임베디드 시스템을 기반으로 환자의 산소치료 선호패턴 및 치료기록을 DB화하여 환자 맞춤형 산소치료 프로파일을 작성하고, 환자의 이름만 입력하면 산소챔버가 자동적으로 작성된 프로파일 패턴에 따라 산소압을 자동적으로 조정함으로써 산소치료 효과를 극대화 할 수 있다. 향후 관리자의 스마트폰과 연동하여 작동하는 산소챔버용 원격관리 시스템으로 확장함으로써 관리의 용이성 및 산소치료의 안전성을 제고하고 부가가치를 극대화 할 수 있기를 기대한다.

• 동의신경정신과학회지
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• 제24권4호
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• pp.393-402
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• 2013

Objectives: This study is a clinical report of a patient with ADHD and learning disorders who is being treated with hyperbaric oxygen, scalp acupuncture, cognitive enhancement therapy and speech-language therapy. Methods: The BASA-R, BASA-M and REVT tests were used for the diagnosis of learning disorders. For the treatment, hyperbaric oxygen therapy, scalp acupuncture, cognitive enhancement therapy and speech-language therapy were all being used. The Raven's matrix tests were compared for between before and after the abovementioned therapies. Results: After the treatment, Raven's matrix test grade improved from 4 to 5. The improvement of the patient's concentration, communication, motion, confidence, and sleep conditions were observed. Conclusions: These therapies including the hyperbaric oxygen therapy are efficient for the treatment of ADHD and learning disorders.

• 대한임상독성학회지
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• 제11권2호
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• pp.81-88
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• 2013

Purpose: The aim of this study is to investigate current status, indications, and complications of hyperbaric oxygen therapy. Methods: A retrospective investigation of patients who underwent hyperbaric oxygen therapy at a university medical center from September 2004 to August 2013 was conducted based on patients' medical records and results of an email survey for 99 emergency centers. Results: During the study period, a total of 233 patients underwent hyperbaric oxygen therapy. Indications for hyperbaric oxygen treatment of illness or injury were as follows: 1) 151 cases of acute carbon monoxide poisoning(65.4%), 2) flap wound management, including 42 cases(18.2%), 3) skin care transplanted, including 23 cases(10.4%), 4) Burger's disease, including 5 five cases(2.1%), respectively. Total application time$^*$ frequency was 1,088 and total time was 1,239 hours. Among 233 patients who underwent hyperbaric oxygen therapy, 32 patients(13.7%) had complications: 1) otalgia in 21 cases(9.0%), 2) mastoiditis?in six cases(2.6%), 3) hemotympanum in five cases(2.1%), respectively. There were only 8 emergency centers that currently had an operational hyperbaric oxygen chamber in 77 emergency centers(10.4%). Conclusion: Indications identified through this study showed difference from current indications worldwide. It seems necessary that physicians' perception regarding application of hyperbaric oxygen therapy for more indications be changed and improved. A hyperbaric chamber capable of providing respiratory assistance and intensive care is also needed. A good network for sharing treatment experiences and a specialized team for administration of hyperbaric oxygen therapy is also required.

• IEIE Transactions on Smart Processing and Computing
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• 제5권2호
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• pp.107-116
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• 2016

Premature babies of less than 37 weeks gestation might require oxygen therapy as an integral part of treatment and respiratory support. Because of their under-developed lungs, these so-called "preemies" might contract respiratory distress syndrome (RDS). To treat RDS, neonatal oxygen therapy is administered, where controlled oxygen gas is measured as a fraction of inspired oxygen ($FiO_2$). However, exposure to high oxygen content during long treatment could cause oxygen intoxication, which might cause permanent blindness due to retinopathy of prematurity (ROP), whereas insufficient oxygen exposure could cause severe hypoxia. A doctor would use oxygen saturation ($SpO_2$) data and prescribe a dose of $FiO_2$ to maintain $SpO_2$ within a suitable range. One objective is to maintain $SpO_2$ within the acceptable range using $FiO_2$ that is as low as possible. Adjustment of $FiO_2$ would normally be done by nurses every 15 to 30 minutes, which might not be safe in many situations. An error in $FiO_2$ adjustment during a manual procedure could be as large as +/- 2.5%. This paper presents a system that can determine an $FiO_2$ value suitable to the current $SpO_2$ and that automatically adjusts $FiO_2$ with an error clearance of +/- 0.25%.

• The Journal of Korean Physical Therapy
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• 제23권4호
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• pp.23-28
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• 2011

Purpose: To investigate the effects of hyperbaric oxygen therapy (HBOT) on chronic low back pain in elderly patients with impaired functioning in daily life. Methods: 35 subjects with chronic low back pain were randomly allocated into two groups, HBOT group and Placebo group. We applied TENS and mechanical massage to the lower back in both groups. Then 35% oxygen at 1.4 ATA was given to the HBOT group and atmospheric oxygen at 1 ATA to the placebo group. Results: Comparing the HBOT group with the placebo group after performing interventions six times in 2 weeks, a statistically significant difference in the Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) scores was observed between the two groups. There was a statistically significant difference in VAS and ODI scores (56% and 34.97% respectively) between the HBOT group and the placebo group. A statistically significant difference was ascertained in the degree of variables VAS and ODI in the HBOT group. Conclusion: Application of HBOT in chronic low back pain could be beneficial for reducing pain and could help in functional recovery.

• 대한의생명과학회지
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• 제15권2호
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• pp.153-160
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• 2009

Photodynamic therapy(PDT) is a treatment utilizing the generation of singlet oxygen and other reactive oxygen species(ROS), which selectively accumulate in target cells. The aim of present work is to investigate the photodynamic therapy mechanism of 9-HpbD-a-mediated PDT in HeLa cell lines. We studied the general reactive oxygen species(G-ROS) activation after 9-HpbD-a PDT using fluorescence stain with $H_2DCF-DA$. G-ROS activation observed after 9-HpbD-a PDT and higher activation condition was 1 hour after PDT at 0.5 ${\mu}g/ml$ 9-HpbD-a concentration. Sodium azide and reduced glutathione(the singlet oxygen quencher) could protect HeLa cells from cell death induced by 9-HpbD-a PDT. But D-mannitol(the hydroxyl radical scavenger) could not protect cell death. Singlet oxygen played a decisive role in 9-HpbD-a PDT induced HeLa cell death. Type II reaction was the main type of ROS formation at 9-HpbD-a PDT.

• 대한물리치료과학회지
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• 제15권1호
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• pp.21-28
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• 2008

The purposes of this study are to quantify energy expenditure by measuring oxygen consumption while performing occupational therapy activities most commonly used for adult hemiplegia patients, to recommend a optimal dosage of exercise by comparing energy expenditure according to the recovery stage, and to suggest a precaution in the treatment of patients with cardiac disorders. According to Brunnstrom recovery stages in hand function, subjects were allocated to group I(3rd and 4th Brunnstrom recovery stages) and group II(5th and 6th Brunnstrom recovery stages). Outcome measures included oxygen consumption, energy expenditure rate, and heart rate during each activity and in recovery period after the activity. Occupational activities including sanding activity, putty activity, and skateboard activity were carried out for all patients. In sanding and putty activities, there were significant differences of oxygen consumption and energy expenditure during the activity between groupⅠandⅡ(p<0.05), but there were not significant differences of oxygen consumption, energy expenditure and heart rate in the recovery period(p>0.05). In skateboard activity, there were no significant differences in oxygen consumption, energy expenditure and heart rates between the two groups during the activity and in the recovery period(p>0.05). The findings indicates that cardiovascular demands for basic activities usually peformed for a treatment may be depended on the physical recovery of patients with hemiplegia. Therefore, therapeutic activities for patients should be selected with the great care.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2011년도 춘계학술대회 논문집
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• pp.1479-1480
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• 2011

• Tuberculosis and Respiratory Diseases
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• 제40권3호
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• pp.283-291
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• 1993

연구배경 : 장기간의 저농도 산소요법은 저산소혈증을 가진 만성폐쇄성폐질환 환자들의 생존율을 향상시킬 뿐만 아니라 삶의 질을 향상시킨다. 저자들은 재택산소요법을 시행하는 환자의 실태를 알아보고 효과적인 개선책을 알아보기 위하여 추적관찰중인 환자 26예에 대한 임상적 관찰을 하였다. 방법 : 대상환자는 경북대학병원 호흡기내과에서 진료를 받고 있는 환자 가운데 가정에서 장기간의 저농도 산소요법을 시행하고 있는 남자 18명 여자 8명 이었으며 재택산소요법을 시행하기전에 신체적 특성과 병력, 폐기능검사, 심전도, 동맥혈가스 및 말초 혈액검사 소견들과 사용중인 산소용기의 종류, 하루에 흡입하는 시간, 투여산소의 농도, 그리고 사용기간 및 문제점 등에 대해서 조사하였다. 결과 : 원인질환은 만성폐쇄성폐질환 14예, 중증폐결핵의 후유증 9예, 기관지확장증 2예 그리고 특발성 폐섬유증 1예였다. 산소치료의 시행동기는 폐성심이 21예, 운동시 호흡곤란 및 심한 환기장애 4예, 그리고 수면중 산소포화도가 90%미만인 경우가 1예였다. 치료시작전의 동맥혈가스소견의 평균치는 $PaO_2$ 57.7 mmHg, $PaCO_2$ 48.2 mmHg 및 $SaO_2$ 87.7% 였으며 폐활량의 평균치는 VC 2.05 L, $FEV_1$ 0.92 L, $FEV_1$/FVC% 51.9%였다. 사용중인 산소용기는 산소탱크를 사용하는 경우가 19예, 산소농축기를 사용하는 경우가 1예, 산소탱크와 액화산소를 함께 사용하는 경우가 2예, 그리고 산소탱크와 휴대용산소를 함께 사용하는 경우 4예였다. 산소사용 기간은 1년 미만이 3예, 1년에서 2년이 15예, 3년에서 5년이 6예 그리고 9년, 10년 동안 산소요법을 시행한 경우도 각각 1예씩 있었다. 산소농도는 전예에서 2.5L/min 이하를 사용하고 있었고 하루 사용시간은 10예 만이 15시간 이상을 사용하였고 대부분이 짧은 시간 동안만 산소를 사용하고 있었다. 결론 : 효과적인 산소투여를 위해서는 환자 및 주위의 사람들에게 장기간의 저농도 산소요법에 대한 교육이 필요하며 편리하게 사용할 수 있는 산소용기의 구입을 위한 제도적 뒷받침이 필요하다.

• 대한물리치료과학회지
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• 제10권1호
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• pp.38-46
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• 2003

Since the current tendencies show us the increasing number of cerebral palsy children and the standard longevity, we need to find out more research about the following various problems. Therefore I have tried to figure out the difference of oxygen saturation and heart rate between before ambulation and after. Objects chosen are 17 C.P children on the process of treatment those who were able to walk and 8 normal children in Ah-San hospital, Gang-Nung. They haven't had either any operation or suffered heart disease and I measured their oxygen saturation and heart rate by using pulse-oximeter and are analyzed by SPSS (10.07 version). Results are the followings; 1. There was no difference of oxygen saturation and heart rate between pre-ambulation and post-ambulation of normal and spastic hemiplegia children. 2. There showed the significant statistic difference of oxygen saturation, heart rate between pre-ambulates and post-ambulation of normal and spastic diplegia(p<.05). 3. There was no difference of oxygen saturation, heart rate in C.P between(p>.05), but shows the significant statistic difference in heart rate(p<.05). As I compared the oxygen saturation and heart rate of spastic and normal children on between pre-ambulation and post-ambulation, theres is significant statistic difference on both items (p<.05). However there was no difference of oxygen saturation among hemiplegia, normal and diplegia children while the pulse rate showed the significant difference(p<.05). According to this clinical research, CP children's oxygen saturation and heart rate had no change between pre and post compared to normal children. But there was difference in diplegia. This is why we need to invest time to study these kinds of research about various analysis and comparison of oxygen saturation and heart rate, and furthermore making use of pulse-oxymetry in physical therapy room for the children involved would be beneficial to calculate in accuracy without any discomfort for the patient as well.