• Title/Summary/Keyword: overall time

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Impact of Time Interval Between Chemoradiation and Surgery on Pathological Complete Response and Survival in Rectal Cancer

  • Akbar, Ali;Bhatti, Abu Bakar Hafeez;Niazi, Samiullah Khan;Syed, Amir Ali;Khattak, Shahid;Raza, Syed Hassan;Kazmi, Ather Saeed
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.89-93
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    • 2016
  • Background: Limited data are available regarding the impact of time duration between chemoradiation (CRT) and surgery on pathological complete response (PCR). A PCR translates into better overall and disease free survival. The objective of this study was to determine effect of time duration on outcome after preoperative CRT in rectal cancer. Materials and Methods: A retrospective review of patients undergoing operations for rectal adenocarcinoma between January 2005 and December 2010 was performed. Patients were divided in two groups: Group 1 underwent surgery in ${\leq}8weeks$ post neoadjuvant CRT and Group 2 after 8 weeks. Patient characteristics, surgical procedure, histopathological details and number of loco-regional and distant failures were compared. Expected 5 year overall survival and disease free survival was calculated using Kaplan Meier curves and significance was determined using the log rank test. Results: There were 66 patients in group 1 and 93 in group 2. No significant difference in PCR was observed between the two. However, estimated 5 year DFS was significantly higher in Group 1 (66.7%) as compared to Group 2 (53.8%) (P=0.04). Estimated overall 5 year overall survival was not significantly different at 68.2% versus 54.3% (P= 0.09). Conclusions: Delaying surgery more than 8 weeks after preoperative CRT does not impact for PCR in rectal cancer.

Optimization of the Preparation of Rice Snack by Response Surface Methodology (반응표면분석법을 이용한 쌀과자의 제조 최적화)

  • Choi, Ok Ja;Jung, Hee Nam;Kim, Young Doo;Shim, Jae-Han;Kwak, Sang Ho;Shim, Ki Hoon
    • Korean journal of food and cookery science
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    • v.30 no.4
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    • pp.454-462
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    • 2014
  • This study aimed at the optimization and development of rice snack by response surface methodology (RSM). The effect of rice soaking time and additional ratio of soybean milk on physicochemical properties and sensory evaluation of dried rice flour for non-fried snack was studied. After soaking for 0 to 12 days, Baekjinju rice was milled and then air-dried. A quadratic model was selected for weight, volume, hardness, taste and appearance. Two-factor interaction model was selected for expansibility, color and overall preference. A linear model was selected for yellowness and flavor. Weight, hardness and appearance were increased and decreased thereafter as rice soaking time increased, but the volume was reversed. Expansibility, color, taste and flavor were decreased as rice soaking time increased, but yellowness was reversed. Weight and overall preference decreased as additional ratio of soybean milk increased, but volume, expansibility and yellowness were reversed. Hardness, taste and appearance were increased after initial decrease as additional ratio of soybean milk increased, color and flavor were not changed by additional ratio of soybean milk. The optimum conditions of each factor were set to where the rice soaking time and additional ratio of soybean milk were at their minimum. Weight, volume, expansibility, yellowness, hardness, color, taste, flavor, appearance and overall preference were established at maximum level where the objective of the optimum was in level. Our data indicated the statistically predicted values of the highest desirability was 1.24 day of rice soaking time and 15.80% of additional ratio of soybean milk.

Propose Tonal Noise Evaluation Method for Air-conditioner based on Customer's Sensory Evaluation (소비자 감성 평가에 의한 에어컨 Tonal Noise 평가 방법 제안)

  • Lee, Jin-Kyung;Lee, Jea-Won;Joo, Jae-Man
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.05a
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    • pp.154-157
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    • 2005
  • Generally, noise from a indoor air conditioner has been measured by overall sound pressure level, dB. Customers evaluation, however, of the noise from an air conditioners should not be depend on the only overall level but also the sensory feeling. Moreover, in this sensory evaluation, irregular, time-varying and uneven sounds which are difficult to describe itself by overall level are more affectable. Unfortunately however the formal evaluation method for this kinds of noise is not determined yet. In this research, the evaluation method for tonal noise, which is one of the unmeasurable sounds by overall level, is proposed to evaluate its acceptability based on the consumer's sense of hearing. To consider the consumer's sense, several times of Jury evaluation are carried out. The proposed approach could be applied to the other sound, which acoustical characteristics are similar to the tonal noise .

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New Methods to Split Overall Gear Ratio of the Cylindrical Multi-Stage Gear Train (원통 기어로 구성된 다단 기어열의 기어비 분할법 개발)

  • 배인호;정태형
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.11 no.6
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    • pp.45-51
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    • 2002
  • The existing methods to split overall gear ratio of the cylindrical multi-stage gear train have their own limitations to be used in practical design and are also problematic to be implemented in a formalized algerian. This paper proposes two types of new methods to find gear ratios best approximating the overall gear ratio. The proposed methods are quite general to be applied to the gear train having any number of stages, and offer a considerably good result in a very short time. The first method uses the random search method and the second one is based on the simulated annealing algorithm. The proposed algorithms are expected to be very useful not only as an independent program to split overall gear ratio, but also as a desist sub-module for the integrated desist system of multi-stage gear drives.

Superconducting Properties of in situ Formed Multifilamentary Cu - Nb3Sn Composites and the Effects of Ti Addition on the Superconducting Properties (I) (In situ 법에 의한 Cu-Nb3Sn 복합재료선재의 초전도특성과 이에 미치는 Ti의 영향(I))

  • Park, H.S.;Suh, S.J.;Lee, U.D.;Ahn, J.M.
    • Journal of the Korean Society for Heat Treatment
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    • v.6 no.1
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    • pp.17-25
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    • 1993
  • The Cu - $Nb_3Sn$ composites wire as a superconducting material was prepared by in situ method as follow: Cu - 15wt.% Nb alloys which were melted in a high -frequency induction furnace and casted in bar were cold-worked up to the final diameter of 0.24 mm, electroplated with Sn, pre-treated in two steps and then diffused at $550{\sim}650^{\circ}C$ for 24 ~ 96 hrs. The overall $J_c$ and $T_c$ of the specimens were measured by the four point-probe method at 10 K in the magnetic field of 0 Tesla. The overall $J_c$ of the composites wire which diffused at $550^{\circ}C$ after pre-treating in two steps were generally higher than those of the wire at either $600^{\circ}C$ or $650^{\circ}C$. For the specimens diffused at $550^{\circ}C$, the overall $J_c$ were increased until 72 hrs. of diffusion time and then decreased. However, in case of diffusion at $600^{\circ}C$ and $650^{\circ}C$, the overall $J_c$ were gradually decreased from the beginning. The maximum overall $J_c$ obtained in this experiment was $1.3{\times}10^4\;A/cm^2$, which was measured for the specimen diffused at $550^{\circ}C$ for 72 hrs. When the specimens were diffused at $550^{\circ}C$ for 72 hrs, after pre-treating, the measured critical temperature, $T_c$ was 16.19 K. Similar $T_c$ value were obtained in other specimens regardless of diffusion time and temperature.

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The Effect of Processing Condition on Preference in Sensory Quality of Pine Nut Gruel (잣죽의 제조조건이 관능적 품질의 기호도에 미치는 영향)

  • Zhang, Xian;Lee, Fan-Zhu;Kum, Jun-Seok;Ahn, Tae-Hoi;Eun, Jong-Bang
    • Korean Journal of Food Science and Technology
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    • v.35 no.1
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    • pp.33-37
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    • 2003
  • Sensory quality of pine nut gruel was investigated to determine the effects of processing conditions on its quality. Response surface methodology was applied to investigate effects of water volume and pine nut weight ratios to rice weight and heating time on the preference of pine nut gruel in terms of color, flavor, viscosity, taste, and overall acceptance. Results showed that processing conditions did not affect the color of pine nut gruel. Viscosity and overall acceptance were affected by the ratio of water volume to rice weight and heating time. $R^2$ of response surface regression equations were 0.6954, 0.8333 (p<0.05), 0.9668 (p<0.01), 0.8664 (p<0.05), and 0.8159 (p<0.10) for color, flavor, viscosity, taste, and overall acceptance respectively. No relationship was observed between color and overall acceptance. The relationship between viscosity and overall acceptance was the highest.

The Influence of Compression Holding Step on Mechanical Properties of Products in Closed-Die Compression Process for Semi-Solid Material (반융용 재료의 밀폐 압축 공정에서 가압유지 단계가 제품의 기계적 성질에 미치는 영향)

  • 최재찬;박형진;이병목
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1995.10a
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    • pp.199-203
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    • 1995
  • The technology of Semi-Solid Forging (SSF) has been actively developed to fabricate near-net- shape products using light and hardly formable materials, the SSF process is composed of slug heating, forming, compression holding and ejecting step. After forming step in SSF, the slug is compressed during a certain holding time in order to be completely filled in the die cavity and be accelerated in solidification rate. The compression holding time that can affect mechanical properties and shape of products is important to make decision, where it is necessary to find overall hert transfer coefficeient properly which has large effect on heat transfer between slug and die. This paper presents the procedure to predict compression holding time of octaining the final shaped part with information of temperature and solid fraction for a cylindrical slug at compression hoiding step in closed-die compression process using heat transfer analysis considering latent heat by means of finite element method. The influence of the predicted compression hoiding time on mechanical properties of products is finally investigated by experiment.

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Quality Characteristic of Low Salted Yacon Jangachi Using Soybean Sauce (간장을 이용한 저염 야콘 장아찌의 품질특성)

  • Shim, Ki-Hoon
    • The Korean Journal of Community Living Science
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    • v.23 no.1
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    • pp.79-88
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    • 2012
  • To evaluate the possibility of low-salinity of traditional fermented food, we investigated quality characteristic of low-salted Yacon Jangachi using soybean sauce with sugar or vinegar for 50 days. Sugar content, titration acidity, and salinity of all Yacon Jangachi was increased as storage time increased. All of the Yacon Jangachi had less than 3.0% salinity. Especially, the salinity of the Yacon Jangachi with sugar and vinegar was the lowest during storage time. The L value was decreased as storage time increased but the results of the a and b values were reversed. Cutting force was not significant among samples and storage periods. In the results of sensory evaluation, preference of all samples were increased as storage time increased. The preference of color was not significant among samples from 30 days but the taste was reversed. The preference of flavor was significant between samples in 40 days, texture was not significant during storage time. Overall preference was not significant after 30 days, which suggested that Yacon Jangachi using soybean sauce retains overall preference in steady level from 30 days. Yacon Jangachi using soybean sauce showed the highest preference when produced with sugar and vinegar.

Physicochemical Characteristics of Jujube Concentrates Prepared by Boiling (가열처리한 대추 농축액의 물리화학적 특성)

  • Park, Byung-Hak;Chae, Kyung-Yeon;Hong, Jin-Sook
    • Journal of the East Asian Society of Dietary Life
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    • v.18 no.2
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    • pp.190-197
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    • 2008
  • The aim of this study was to determine the optimal cooking conditions in preparing jujube concentrates using various boiling times (5, 10, 15, 20 hours). The moisture contents of the concentrate samples ranged from 38.86 to 42.36%. Crude protein content was highest in the 15 hr-boiled concentrate, crude fat was highest in the 20 hr-boiled concentrate and both the 15 and 20 hr boiled concentrates had high crude fiber contents. There were no differences in color L- and a-values by boiling time; however, the b-value decreased with increasing boiling time. The pH levels of the concentrates ranged from 5.24 to 5.27, and the brix level increased with increasing boiling time. Glucose was the primary of free sugar in the concentrates and its highest level was 102.3 ${\mu}M$ in the 20 hr-boiled concentrate. The 15 hr-boiled concentrate had the highest electron donating ability to 46.68%. The total polyphenol contents of the concentrates ranged from 21.53 to 24.56%, in which the 15-boiled concentrate had the highest level (24.56%). In the sensory evaluation, the 15-hr-boiled concentrate again performed well, showing the highest overall acceptability scores. From these results, 15 hrs was the optimal boiling time for preparing jujube concentrate in terms of obtaining functional compounds and overall product acceptability.

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Development of Salted Semi-dried Common Gray Mullet Mugil cephalus using Response Surface Methodology (Response Surface Methodology를 이용한 숭어(Mugil cephalus) 반염건품의 개발)

  • Park, Kwon Hyun;Heu, Min Soo;Kim, Jin-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.48 no.6
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    • pp.839-848
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    • 2015
  • This study examined the optimal salting drying method and processing conditions (salt concentration, curing time, dry temperature, and drying time) for preparing salted semi-dried common gray mullet (SSD-CGM) Mugil cephalus based on the moisture content, salinity, and overall acceptance using response surface methodology (RSM). The moisture content, salinity, and overall acceptance of SSD-CGM prepared with different salting methods revealed that dry salting was the optimal salting method for preparing high-quality SSD-CGM. The optimal drying method for preparing high-quality SSD-CGM based on the drying velocity and sensory color was hot air-blast drying. The results of the RSM program indicated that the optimal independent variables ($X_1$, salt concentration; $X_2$, curing time; $X_3$, dry temperature; $X_4$, drying time) based on the dependent variables ($Y_1$, moisture content; $Y_2$, salinity; $Y_3$, overall acceptance) for high-quality SSD-CGM were 5.6% for $X_1$, 2.7 h for $X_2$, $47.0^{\circ}C$ for $X_3$, and 8.5 h for $X_4$ for uncoded values. The predicted values of $Y_1$, $Y_2$, and $Y_3$ for SSD-CGM prepared under optimal conditions were 54.4%, 4.2%, and 6.3, respectively, while the experimental values were $55.2{\pm}1.0%$, $4.1{\pm}0.3%$ and $6.7{\pm}0.8$. The actual and predicted values did not differ.