• 대한유전성대사질환학회지
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• 제15권3호
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• pp.160-164
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• 2015

Hunter syndrome(Mucopolysaccharidosis type II, MPS type II) is an X-linked disorder of glycosaminoglycans (GAGs) metabolism caused by an iduronate-2-sulfatase (IDS2) deficiency. A 24-month-old boy visited the department of pediatrics with the chief compliant of chronic purulent rhinorrhea beginning at age one. He had a history of repeated acute otitis media and chronic rhinitis. On physical examination he had a coarse face, enlarged tongue, distended abdomen, joint stiffness, and Mongolian spots at his first visit. The urine GAGs level was elevated at 66.10 mg/mmolCr (reference range, <11.1) and iduronate-2-sulfatase activity in leukocyte was decreased at 0.21 nmol/mg protein/hr (reference range, 18.7-57). Finally with an IDS gene mutational analysis, recombinant known mutation between intron 7 and distal of exon 3 in IDS2 was detected. Recombinant iduronate-2-sulfatase therapy was started without any infusion related reactions. The author highlights the importance of suspecting Hunter syndrome when pediatric patients visit with chronic purulent rhinorrhea which is a common cause of hospital visits for infants and children.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1987년도 제21차 학술대회 연제순서 및 초록
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• pp.11.3-12
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• 1987

삼출성 중이염은 소아연령군의 이비인후과질환중 유병율이 가장 높은 질환의 하나로 1867년 Politzer가 최초로 기술하고 치료법을 소개한 이후 그 병인 및 치료법이 다양하게 연구 개발되어 왔으며 1950년대 및 1960년대 electroacoustic impedance unit의 발전에 따라 진단법에 많은 변혁이 이루어졌다. 연자들은 1981년 1월1일 부터 1986년 12월31일까지 삼출성 중이염으로 중이내 통기관유치술 및 고막천자를 시행한 15세 이하의 290명의 환자를 대상으로 tympanogram의 양상 및 술전 기골도차를 조사하여 중이내 삼출액의 유무 및 점성도의 예측도에 대하여 살펴 보았다. Tympanometric peak pressure (T. P. P.) 가 -50mm$H_2$O 미만이며 compliance가 0.4 c.c.미만인 영역을 B영역으로. T.P.P.가 -50mm$H_2$O 미만이며 compliance가 0.4 c.c. 이상인 영역을 C영역으로 정하였을 때 중이내 삼출액 유무의 예측도는 B영역이 87.5%. C영역은 81.48%였으며 삼출액이 장액성일 경우의 예측도는 B영역이 24.51%, C영역이 22.72%이었고, 삼출액이 점액성일 경우의 예측도는 B영역이 70.39%, C영역이 54.54%이었다. 연령을 15세 - 7세군과 6세이하의 군으로 세분하였을 경우에도 비슷한 결과를 얻었다.

• 한방안이비인후피부과학회지
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• 제17권3호
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• pp.88-94
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• 2004

Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement of one side face. In the treatment of hemifacial spasm, the Western operation or non-operation therapy has many side effect such as hearing loss, exudative otitis media, facial paralysis etc. So we studied mainly the effect of cause, treatment frequency, diseased part of 29 cases with hemifacial spasm for effective clicical application of oriental medicine. The results of study are as follow; 1. It shows more female patients than male patients, and mostly patients in their forties. 2. The diseased part is shown more on left side than right side, and the left side hemifacial spasm is cured more effective. 3. The causes of hemifacial spasm are mainly stress, ignorance, overwork, and the stress, a cold are more effective causes than ignorance in. 4. The disease period is mainly within six months, and that period is the most effective time. 5. The palpebral site is the most frequent site, ineffective site. 6. The effect go with the treatment frequency is not available. 7. There is a 55 percent improvement of 29 cases.

• 대한장애인치과학회지
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• 제7권2호
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• pp.119-122
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• 2011

연골무형성증 환아는 작은 키, 짧은 사지, 척추 측만, 아데노이드와 편도 비대 등의 특징적인 소견으로 인해 치과치료시 많은 주의를 요한다. 대부분의 환자들이 구호흡을 하기 때문에 치과 시술시 호흡이 어려우며, 척추 이상으로 인해 체어에 오래 누워있기 힘든 경우가 많아 이번 증례와 같이 다발성 우식증을 치료하기 위해서는 전신마취 하 시술이 필요한 경우도 있다. 연골무형성증 환아의 치과 진료시에는 타과와의 긴밀한 협조 하에 이러한 전신적인 특징을 이해하고 접근해야 할 것이다.

• 한국보건간호학회지
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• 제25권2호
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• pp.197-208
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• 2011

Background: This study investigated the hearing status in Korean adults according to data from the Korea National Health and Nutrition Examination Survey 2009. Methods: The data of 3,479 adults(${\geq}20$ years, 1,492 men, 1,987 women) collected by the Korean Center for Disease Control was analyzed using ${\chi}^2$-test and logistic regression. Results: Differences in hearing loss according to individual factors were evident by follows gender, region, education status, economic status, current smoking and recognition of stress. Differences in - hearing loss according to ear related factors were evident subjective hearing status, experience of tinnitus, prevalence of chronic otitis media, and tympanomembrane abnormality. Conclusion: Hearing-related disorders can cause many social problems. This study investigated a representative cross-section of Koreans to determine the hearing status. The study was limited in that the risk factors of hearing loss were not identified. It is also recommended that a program be developed that can help control the variables identified in this study along with follow-up studies to verify the model.

• Journal of the Optical Society of Korea
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• 제15권1호
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• pp.74-77
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• 2011

We report a novel extension of 840 nm wavelength- based spectral domain optical tomography to in vivo/real-time human middle ear diagnosis. The system was designed to access the middle ear region with a specifically dedicated handheld probe. The real-time displaying feature was mandatory for in vivo imaging human subject with the handheld probe, and the system could provide about 20 frames per second for 2048 pixels by 1000 A-scans without using any graphics process units under the Labview platform. The inner ear structure of a healthy male volunteer was imaged with the developed system with the axial and lateral resolutions of $15\;{\mu}m$ and $30\;{\mu}m$, respectively. The application of the OCT technology to early diagnose otitis media(OM) is very promising and could be another extensive branch in the OCT field because it provides the depth resolved image including tympanic membrane (TM) and structures below TM whereas the conventional otoscope technique only gives asurface image of the TM.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권12호
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• pp.705-709
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• 2018

It is challenging to achieve sufficient hearing gain in patients with mixed hearing loss. In chronic middle ear diseases, conventional passive reconstructive surgeries often result in suboptimal hearing gain and additional hearing aids may have limitations due to insufficient sound amplification, occlusion effect, acoustic feedback, and skin irritation. Middle ear implantation (MEI) using Vibrant Soundbridge (VSB) is another option for auditory rehabilitation in mixed hearing loss as well as sensorineural hearing loss. The floating mass transducer of VSB can be placed on various middle ear structures either directly or using different types of couplers in order to deliver vibratory mechanical energy to the cochlea. We report a patient who presented with bilateral mixed hearing loss due to chronic otitis media and had limitations using conventional hearing aids in the worse hearing ear. The patient was successfully treated with MEI using the Bell coupler together with middle ear surgery in a single step.

• 한국해양바이오학회지
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• 제13권1호
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• pp.48-57
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• 2021

Vibrio species are Gram-negative basophils that are ubiquitous in seawater, increasing in number as the water temperature increases. Humans are usually infected by the consumption of contaminated seawater or seafood. V. alginolyticus infection in humans is mainly associated with infections of the skin and ears, such as acute otitis media and cellulitis. In this study, the distribution of V. alginolyticus along the coast of Jeju Island, and its relationship with water temperature, salinity, DO, and pH was investigated. The antibiotic susceptibility of the bacteria isolated was also tested. In seawater, the Daejeong area had the highest detection rate, with 13 cases (21.7%), and the Hallim area showed the lowest detection rate, with eight cases (13.3%) in. In shellfish, the Daejeong area had the highest rate, with seven cases (23.3%), and the Seongsan and Hallim areas had the lowest detection rate, with four cases (13.3%). The overall detection rate was the highest in Daejeong area, with 20 cases (22.2%), and the lowest in the Hallim area, with 12 cases (13.3%). The detection rate was highest when the water temperature was highest.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1972년도 춘계종합 학술대회 초록집
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• pp.1.2-1
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• 1972

만성중이염의 원인균에 대해서는 여러가지 방면으로 고찰되어 왔다. 저자들은 시대에 따르는 원인균의 분포와 아울러 새로운 항생제제의 개발에 따르는 내성 및 감수성의 정도와 변화 등을 고찰하기 위하여 임의로 선택된 중이염환자의 이루에서 채취된 세균에 대해 이를 분류하고 각종 항생제에 대한 감수성을 검사하였기에 보고한다. 65이에서 분류된 65균주에 대해 Ampicillin Chloramphenicol, Erythromysin, Kanamycin, Gentamycin, Orbenin, penicillin, Streptomycin, Terramyin 및 Colimycin등 10종류의 항생제제에 대한 감수성 청사를 하였다. Gram-negative 군인 pseudomonas(12례, 18.5%)에서는 Colimycin에 91.7% 및 Gentamycin에는 75%의 순으로 감수성이 높았고 proteus (11례 16.9%)에 가장 감수성이 높은 약제는 Ampicillin 81.8%이고 Genta-mycin에 81.8% 등이었다. Gram-positive인 Staphyloccus aureus(19례 29.2%)에서는 Erythromyin에 100% Orbenin에 94.7%의 순으로 감수성이 높았다.

• Journal of Chest Surgery
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• 제43권6호
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• pp.816-819
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• 2010

호너 증후군은 폐쇄식 흉강삽관술 후 발생할 수 있는 드문 합병증으로 이를 치험하여 보고하고자 한다. 17세 여자 환자로 2번째 발생한 좌측 기흉으로 폐쇄식 흉강삽관술 시행 후 수술 위해 입원하였다. 입원 후 우측 중이염 발생으로 항생제 치료 중 폐쇄식 흉강삽관술 후 3일째 흉관 삽입한 동측 동공 축동과 눈꺼풀 처짐을 증상으로 하는 호너 증후군이 발생하였고, 즉시 흉관을 2~3 cm 잡아 빼서 흉관의 위치를 교정하였다. 폐쇄식 흉강삽관술 후 5일째 기흉에 대한 낭포 절제술과 기계적 흉막 유착술을 시행하였고, 특별한 문제 없이 수술 후 7일에 퇴원하였다. 수술 후 호너 증후군으로 인한 증상은 점차 호전되었고, 2달만에 완전히 회복하였다.