• 대한수학회지
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• 제54권4호
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• pp.1281-1299
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• 2017

A submodule N of a module M is called ${\mathcal{S}}$-closed (in M) if M/N is nonsingular. It is well-known that the class Closed of short exact sequences determined by closed submodules is a proper class in the sense of Buchsbaum. However, the class $\mathcal{S}-Closed$ of short exact sequences determined by $\mathcal{S}$-closed submodules need not be a proper class. In the first part of the paper, we describe the smallest proper class ${\langle}\mathcal{S-Closed}{\rangle}$ containing $\mathcal{S-Closed}$ in terms of $\mathcal{S}$-closed submodules. We show that this class coincides with the proper classes projectively generated by Goldie torsion modules and coprojectively generated by nonsingular modules. Moreover, for a right nonsingular ring R, it coincides with the proper class generated by neat submodules if and only if R is a right SI-ring. In abelian groups, the elements of this class are exactly torsionsplitting. In the second part, coprojective modules of this class which we call ec-flat modules are also investigated. We prove that injective modules are ec-flat if and only if each injective hull of a Goldie torsion module is projective if and only if every Goldie torsion module embeds in a projective module. For a left Noetherian right nonsingular ring R of which the identity element is a sum of orthogonal primitive idempotents, we prove that the class ${\langle}\mathcal{S-Closed}{\rangle}$ coincides with the class of pure-exact sequences of modules if and only if R is a two-sided hereditary, two-sided $\mathcal{CS}$-ring and every singular right module is a direct sum of finitely presented modules.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권11호
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• pp.1959-1975
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• 2011

Adaptive Bit Loading (ABL) in Multiple-Input Multiple-Output Orthogonal Frequency-Division Multiplexing (MIMO-OFDM) is often used to achieve the desired Bit Error Rate (BER) performance in wireless systems. In this paper, we discuss some of the bit loading algorithms, compare them in terms of the BER performance, and present an effective and concise Adaptive Grouped Loading (AGL) algorithm. Furthermore, we propose a "weight factor" for loading algorithm to converge rapidly to the final solution for various data rate with variable Signal to Noise Ratio (SNR) gaps. In particular, we consider the bit loading in near optimal Singular Value Decomposition (SVD) based MIMO-OFDM system. While using SVD based system, the system requires perfect Channel State Information (CSI) of channel transfer function at the transmitter. This scenario of SVD based system is taken as an ideal case for the comparison of loading algorithms and to show the actual enhancement achievable by our AGL algorithm. Irrespective of the CSI requirement imposed by the mode of the system itself, ABL demands high level of feedback. Grouped Loading (GL) would reduce the feedback requirement depending upon the group size. However, this also leads to considerable degradation in BER performance. In our AGL algorithm, groups are formed with a number of consecutive sub-channels belonging to the same transmit antenna, with individual gains satisfying predefined criteria. Simulation results show that the proposed "weight factor" leads a loading algorithm to rapid convergence for various data rates with variable SNR gap values and AGL requires much lesser CSI compared to GL for the same BER performance.

• 대한의용생체공학회:의공학회지
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• 제33권4호
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• pp.169-176
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• 2012

Tumor cell morphology is closely related to its migratory behaviors. An active tumor cell has a highly irregular shape, whereas a spherical cell is inactive. Thus, quantitative analysis of cell features is crucial to determine tumor malignancy or to test the efficacy of anticancer treatment. We use 3D time-lapse phase-contrast microscopy to analyze single cell morphology because it enables to observe long-term activity of living cells without photobleaching and phototoxicity, which is common in other fluorescence-labeled microscopy. Despite this advantage, there are image-level drawbacks to phase-contrast microscopy, such as local light effect and contrast interference ring. Therefore, we first corrected for non-uniform illumination artifacts and then we use intensity distribution information to detect cell boundary. In phase contrast microscopy image, cell is normally appeared as dark region surrounded by bright halo ring. Due to halo artifact is minimal around the cell body and has non-symmetric diffusion pattern, we calculate cross sectional plane which intersects center of each cell and orthogonal to first principal axis. Then, we extract dark cell region by analyzing intensity profile curve considering local bright peak as halo area. Finally, we calculated the Fourier descriptor that morphological characteristics of cell to classify tumor cells into active and inactive groups. We validated classification accuracy by comparing our findings with manually obtained results.

• Archives of Pharmacal Research
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• 제16권3호
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• pp.219-226
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• 1993

For the analysis of structure relationship of ar-turmerone analogues, the compounds containing the various substituents on the phenyl ring and 1(or 2)-naphthyl group in the place of phenyl of ar-turmerone were prepared and tested their cytotoxicity against HL-60, K-562, and L1210 leukemia cells in vitro. The substituents at para position are methoxy, phenoxy, methyl, trifluoromethyl, fluoro, and chloro. At meta position methoxy, methyl, trifluoromethyl, or chloro groups at ortho position mathoxy or chloro group were introduced. Against HL-60 and K-562 cells, $ED_{50}$ values of the analogues are ranged from 0.8 to $30.0\;\mu{g/ml}$. Againste L1210 cell, these are located more than $20.0\;\mu{g/ml}$. However, 5-carbone-thoxy-2-methyl-6(1-naphthyl)-2-octen-4-one (5n)possesses $ED_{50}$ valuses 0.8, 2.1, $6.5\;\mu{g/ml}$ against HL-60, L1210 cells, respectively. The electronic nature of the substituents on phenyl ring of ar-tumerone dose not affect the biological activity. Therefore the flat structure of aromatic potion of ar-tumerone analogues is the more important factor for their activity rather than its electronic nature. The potentiation of the cytotoxicity with the enlargement of aromatic ring region also supports the importance of the plane structure of this area. The restriction of the single bond rotation between C-6 and aromatic ring through the introduction of substituents at the ortho position of phenyl ring and the increment of size of alkyl group at C-6 position enhances the activity. Therefore the effective conformation should by the one having the orthogonal arrangement between the aromatic ring and the side chain.

• 한국건축시공학회지
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• 제2권4호
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• pp.89-98
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• 2002

Self-leveling material(SLM) is one of the floor finishing materials which make flat surface like as water level by itself in a short time. So it is possible to increase construction speed and enhance economical efficiency In this study, author intended to develop SLM for the industrial warehouse and factory loading heavy weight machinery and vehicles. The demanded properties for this type of SLM are above 200mm of flow value and above 300kgf/$cm^2$ of 28-days compressive strength. To possess demended strength and fluidity, SLM have to be composed of many types of binders and chemical additives. So it is difficult to decide suitable mixing proportion of composition materials. In this study, author investigated the weight percentage effect of main composition materials for high-strength self-leveling material, by experimental design such as tables of orthogonal arrays and simplex design, and by statistical analysis such as analysis of variance and analysis of response surface. Variables of experiments were ordinary Portland cement(OPC), alumina cement(AC), anhydrous gypsum(AG), lime stone(LS) and sand, and properties of tests were fluidity of fresh state and strength of hardened state. Results of this study are showed that suitable mix proportions of binders for the high strength self-leveling materials are two groups. One is 78~85.5% OPC, 7.5~9.5% AC, 9~12.5% AG and the other is 72.5~78% OPC, 9~12.5% AC, 13~15% AG.

• 한국산학기술학회논문지
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• 제11권7호
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• pp.2623-2631
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• 2010

본 논문에서는 다중 전송률을 갖는 다중 캐리어(MC) DS/CDMA 시스템에서 OVSF코드를 사용한 새로운 코드 그룹화 간섭제거기를 제안한다. 사용자들은 가변처리이득을 만족하기 위하여 전송률에 따라 길이가 다른 OVSF 코드를 할당하며 대표코드가 같은 OVSF 코드를 사용하는 사용자들을 그룹화 한다. 제안된 코드그룹화 간섭제거기는 그룹간 간섭을 제거한 후 그룹내 간섭을 차례로 제거한다. 간섭제거기는 간섭사용자들의 정확한 정보 없이 원하는 사용자의 코드 정보만 알고 있어도 간섭제거 및 사용자신호의 검출이 가능하다. 제안된 시스템은 그룹 단위의 처리를 통하여 간섭을 보다 쉽고 간단하게 제거함으로써 성능이 향상되며 기존 방식보다 효율적인 시스템을 구현할 수 있다. BER 성능을 주파수 선택적 레일리 페이딩 채널 하에서 분석하였으며 제안된 시스템을 다중 전송률 DS/CDMA 시스템과 비교하였다. 제안한 시스템을 동일 대역폭과 동일 처리이득에 따라 성능을 분석하였으며, 간섭제거기를 사용하여 성능이 향상됨을 알 수 있다.

• Design & Manufacturing
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• 제15권1호
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• pp.48-56
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• 2021

The quality of products produced by injection molding process is greatly influenced by the process variables set on the injection molding machine during manufacturing. It is very difficult to predict the quality of injection molded product considering the stochastic nature of manufacturing process, because the process variables complexly affect the quality of the injection molded product. In the present study we predicted the quality of injection molded product using Artificial Neural Network (ANN) method specifically from Multiple Input Single Output (MISO) and Multiple Input Multiple Output (MIMO) perspectives. In order to train the ANN model a systematic plan was prepared based on a combination of orthogonal sampling and random sampling methods to represent various and robust patterns with small number of experiments. According to the plan the injection molding experiments were conducted to generate data that was separated into training, validation and test data groups to optimize the parameters of the ANN model and evaluate predicting performance of 4 structures (MISO1-2, MIMO1-2). Based on the predicting performance test, it was confirmed that as the number of output variables were decreased, the predicting performance was improved. The results indicated that it is effective to use single output model when we need to predict the quality of injection molded product with high accuracy.

• 인간식물환경학회지
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• 제23권5호
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• pp.495-506
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• 2020

Background and objective: This study conducted a conjoint analysis on early childhood teachers to find out their preferences in horticultural activities that are used as a means of education in early childhood education. Methods: For the conjoint analysis, five attributes of horticultural activities were selected. Attribute 1 was method of horticultural activities, divided into two levels: exclusive and integrated horticultural activities. Attribute 2 was object of horticultural activities, divided into three levels: fruit crops, vegetable crops, and floricultural crops. Attribute 3 was activity type, divided into three levels: big and small group, free choice, and outdoor play. Attribute 4 was place for horticultural activities, and divided into two levels: indoors and outdoors. Attribute 5 was time for horticultural activities, divided into two levels: 30 minutes and 30-60 minutes. The orthogonal design was used to extract 20 profiles, after which we conducted a survey on 320 early childhood teachers and analyzed the valid responses from 257 teachers. Results: The preference of early childhood teachers showed highest importance in object (29.1%), followed by activity type (23.2%), activity method (17.4%), time (16.1%), and place (14.2%) (Pearson's R = .591, p = .008). By level of each attribute, the importance was high in exclusive horticultural activities for activity method, big and small group for activity type, vegetable and floricultural crops for object, indoors for place, and 30 minutes for time. Conclusion: The horticultural program preferred by early childhood teachers is comprised of big and small group activities using vegetable and floricultural crops, carried out indoors for 30 minutes as an exclusive class.

• Animal Bioscience
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• 제35권6호
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• pp.858-868
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• 2022

Objective: This study was conducted to evaluate the effects of dietary yeast hydrolysate (YH) supplementation on intestinal morphology, barrier, and anti-inflammatory functions of broilers. Methods: A total of 320 one day old male broilers were randomly allocated into four groups with eight replicates of ten broilers each. The broilers were supplemented with a basal diet (the control group) or basal diets adding 50, 100, 150 mg/kg YH, respectively. This trial lasted for 42 days. The orthogonal polynomial contrasts were used to determine the linear and quadratic effects of increasing levels of YH. Results: In our previous research, supplementing YH improved growth performance by enhancing body weight gain but decreased feed-to-gain ratio. In this study, compared with the control group, dietary YH addition linearly and quadratically decreased serum diamine oxidase activity (p<0.05). Additionally, supplementing YH linearly and/or quadratically decreased jejunal crypt depth (CD), tumor necrosis factor-alpha (TNF-α) concentration as well as mucin 2, interleukin-6 (IL-6), IL-1β, TNF-α, nuclear factor kappa B, and myeloid differentiation factor 88 gene expression levels (p<0.05). Whereas the jejunal villus height (VH), VH/CD, IL-10 concentration as well as zonula occludens-1 and IL-10 gene expression levels were linearly and/or quadratically increased by YH supplementation (p<0.05). Conclusion: Dietary YH supplementation improved intestinal morphology, barrier and anti-inflammatory functions while decreased intestinal permeability of broilers, which might be related with altering pertinent genes expression. This study provides evidence of YH as a promising feed additive for broilers.

• 농업과학연구
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• 제48권4호
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• pp.875-890
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• 2021

In order to confirm the safety of a genetically modified organism (GMO), we assess its potential toxicity on non-target insects and spiders. In this study, the effects of GM soybean, a type of vitamin-A-enhanced transgenic soybean with tolerance to the herbicide glufosinate, were assessed under a field condition. The study compared this vitamin-A-enhanced transgenic soybean and a non-GM soybean (Gwangan) in a living modified organism (LMO) isolated field of Kyungpook National University (Gunwi) and the National Institute Agricultural Sciences (Jeonju) in the Republic of Korea in 2019 - 2020. In total, 207,760 individual insects and arachnids, representing 81 families and 13 orders, were collected during the study. From the two types of soybean fields, corresponding totals of 105,765 and 101,995 individuals from the vitamin-A-enhanced transgenic soybean and Gwangan samples areas were collected. An analysis of variance indicated no significant differences (p < 0.05). A multivariate analysis showed that the dominance and richness outcomes of plant-dwelling insects were similar. The data on insect species population densities were subjected to a principal component analysis (PCA) and an orthogonal partial least squares-discriminant analysis (OPLS-DA), which did not distinguish between the two varieties, i.e., the vitamin-A-enhanced transgenic soybean and the non-GM soybean in any cultivated field. However, the results of the PCA analysis could be divided overall into four groups based on the yearly survey areas. Therefore, there was no evidence for the different impact of vitamin A-enhanced transgenic soybean on the above-ground insects and spiders compared to non-GM soybean.