• Journal of Sasang Constitutional Medicine
• /
• v.24 no.2
• /
• pp.19-30
• /
• 2012

1. Objectives : The aim of this study was to survey the Original symptoms of Soyangin's and to compare the tendency of their symptoms between Soyangin Gyolhyungjeung and Soyangin Heat-related diarrhea accompanied by headache in patients of indigestion. 2. Methods : We recruited 76 Soyangin subjects in the Korean Medicine clinic and researched their original symptoms. Subjects were diagnosed by the Sasang Constitutional specialists and Sasang Constitutional Medication. Subjects were two groups, confirmed to Soyangin Gyolhyungjeung and Soyangin Heat-related diarrhea accompanied by headache. All subjects answered the questionnaire about their Original symptoms. We found the differences between 2 groups using the Mann-Whitney U Test. Analysis was conducted using SPSS 18.0 for Korean. 3. Results : In Original symptoms, there was no difference between 2 groups in sleep, appetite, digestion, eating habits, water temperature, function of bowel movement, urination, sweating, sensitivity to coldness and sensitivity to warmness. But there was difference between 2 groups in frequency of defecation & hardness of feces(p=0.027). 4. Conclusions : We found the differences of heat and cold in symptoms between two Soyangin syndromes.

• Journal of the Korean Institute of Oriental Medical Informatics
• /
• v.15 no.2
• /
• pp.7-56
• /
• 2009

Objective: The purpose of this study is to compare the original texts with quotations in 16 Kinds of Cough Part in Haesu Chapter of Dong-Yi-Bo-Gam and to find out the ideas of Huh Jun(許浚, 1546-1615; the author of Dong-Yi-Bo-Gam) in there. Methods: I compared the original texts with quotations in 16 Kinds of Cough Part in Haesu Chapter of Dong-Yi-Bo-Gam. Results: 1. There is only one quoted sentence which perfectly matches with original text in 16 Kinds of Cough Part in Haesu Chapter of Dong-Yi-Bo-Gam. The other sentences are all modified while they are quoted by Huh Jun, at least one word. 2. The arrangement order of 'medical effect', 'consisting medicines and their dosages' and 'doctrine in application' were rearranged following the form of Dong-Yi-Bo-Gam when being quoted. 3. In cases of reciting the text, Huh Jun tries to clarify the original source of the context. However, instead of using original quotations he recited rephrased quotes from other sources. 4. Huh Jun cites from not only cough parts of other texts but also asthma(喘症) or heat(積熱) parts. 5. Titles of original text books are recorded in the end of all sentences of Dong-Yi-Bo-Gam, but there are a few wrong titles recorded. Conclusion: In consideration of the above-mentioned, the Dong-Yi-Bo-Gam is not the mere collection of various Oriental Medical books, but the Classic of Oriental Medicine to hold Huh Jun's own opinion.

• Journal of Acupuncture Research
• /
• v.29 no.5
• /
• pp.61-74
• /
• 2012

Objectives : This study is perfomed for preparation of oriental medicine clinical guidelines for drawing up the standards of oriental medicine demonstration and diagnosis classification about the knee pain. Methods : Statistical analysis about Crane's-knee wind(鶴膝風), arthralgia syndrome(痺症), knee injury(膝傷), gout arthritis(痛風), Youk jeol poung(歷節風) classified experts' opinions about knee pain patients by Delphi method is conducted by using oriental medicine diagnosis questionnaire. The result was classified by using linear discriminant analysis(LDA), diagonal linear discriminant analysis(DLDA), diagonal quadratic discriminant analysis(DQDA), K-nearest neighbor classification(KNN), classification and regression trees(CART), support vector machines(SVM). Results : The results are summarized as follows. 1. The result analyzed by using LDA has a hit rate of 81.65% in comparison with the original diagnosis. 2. The result analyzed by using DLDA has a hit rate of 63.3% in comparison with the original diagnosis. 3. The result analyzed by using DQDA has a hit rate of 65.14% in comparison with the original diagnosis. 4. The result analyzed by using KNN has a hit rate of 74.31% in comparison with the original diagnosis. 5. The result analyzed by using CART has a hit rate of 75.23% in comparison with the original diagnosis when the test of selected 13 significant questions based on analysis of variance was performed. 6. The result analyzed by using SVM has a hit rate of 87.16% in comparison with the original diagnosis. Conclusions : Statistical analysis using oriental medicine diagnosis questionnaire on knee pain generally turned out to have a significant result.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.3
• /
• pp.590-595
• /
• 2005

The following conclusions are produced by the consideration of Bojungikki-tang(補中益氣湯) from the view point of Hyungsang medicine. A review on the explanation and provisions of Bojungikki-tang stipulated in 'Donguibogam(東醫寶鑑)' results in the idea that the main purpose of Dongwon(東垣) and various application in clinic by Jeesan(芝山) cannot be understood without the deep comprehension of ki(especially Jungki and Wonki) and the fire. Jungki(中氣, the middle warmer ki) is the ki of stomach. Wonki(元氣, the original ki) is a combination of innate Jung(先天之精, Ki stored between the two kidneys) and acquired Jung(後天之精, Ki of the stomach) and the sources of five Jang and six Bu, twelve meridians and triple warmer. Yin fire is referred to the ministerial fire of spleen, liver and kidney. Excess or lack of the ministerial fire can cause a disease and especially the excess of it is harmful to original ki. Deficiency of original ki is thought to be a cause of allergic diseases. Damages on the original ki by the abdominal surgery lead to a disease. Pale complexion, long face and the long limbs are considered as the Hyungsang of deficiency of Jung ki by Jeesan. Clinical cases of Bojungikki-tang in Hyungsang medicine draw the following conclusions ; Bojungikki-tang is usually prescribed to the person who has one of the following Hyungsang : Bangkwang type, pale complexion, long face, short-sight, astigmatism and wrinkles on face. Bojungikki-tang can be applied to the every disease caused by the deficiency of original ki regardless of name and symptoms of disease.

• Journal of Sasang Constitutional Medicine
• /
• v.23 no.2
• /
• pp.240-253
• /
• 2011

1. Objectives: The purpose of this study was to survey the Original symptoms(素證) of Soyangin's and to compare the tendency of their symptoms between Soyangin Heat-related diarrhea accompanied by headache(身熱頭痛亡陰證) and Soyangin Cold-related diarrhea accompanied by abdominal pain(身寒腹痛亡陰證). 2. Methods: We recruited 56 Soyangin subjects in the Korean Medicine clinic and researched their original symptoms. Subjects were diagnosed by the Sasang Constitutional specialists and Sasang Constitutional Medication. Subjects were two groups, confirmed to Soyangin Heat-related diarrhea accompanied by headache and Soyangin Cold-related diarrhea accompanied by abdominal pain. All subjects answered the questionnaire about their Original symptoms. We found the differences between 2 groups using the Independent-Samples T-test. Analysis was conducted using SPSS 12.0 for Korean. 3. Results and Conclusions: In Original symptoms, Tendency of overeating(p=0.01), Condition of digestion(p=0.04), Perspiration after exercise (p=0.02), Usual perspiration(p=0.00), Tiredness after perspiration(p=0.05) Cold intolerance on extremities(p=0.04), General edema(p=0.01) etc. are different between 2 groups. We found the differences of heat and cold in symptoms between two Soyangin syndromes.

• BMB Reports
• /
• v.52 no.12
• /
• pp.689-694
• /
• 2019

Ethical and safety issues have rendered mesenchymal stem cells (MSCs) popular candidates in regenerative medicine, but their therapeutic capacity is lower than that of induced pluripotent stem cells (iPSCs). This study compared original, dental tissue-derived MSCs with re-differentiated MSCs from iPSCs (iPS-MSCs). CD marker expression in iPS-MSCs was similar to original MSCs. iPS-MSCs expressed higher in pluripotent genes, but lower levels in mesodermal genes than MSCs. In addition, iPS-MSCs did not form teratomas. All iPSCs carried mtDNA mutations; some shared with original MSCs and others not previously detected therein. Shared mutations were synonymous, while novel mutations were non-synonymous or located on RNA-encoding genes. iPS-MSCs also harbored mtDNA mutations transmitted from iPSCs. Selected iPS-MSCs displayed lower mitochondrial respiration than original MSCs. In conclusion, screening for mtDNA mutations in iPSC lines for iPS-MSCs can identify mutation-free cell lines for therapeutic applications.

• Journal of Korean Medical classics
• /
• v.23 no.1
• /
• pp.217-233
• /
• 2010

"Singijonmangron(神氣存亡論; theory of mind-spirit activities)" is a medical discourse of Janggyeongak(張景岳) in the Ming[明] dynasty, and "Wongijonmangron(元氣存亡論; theory of original gi functioning)" is a work by Seoryeongtae(徐靈胎) in the Qing[淸] dynasty. One emphasized the importance of mind-spirit activities and the other said seriously about original gi functioning. We did a study on these two medical theories, and began with identifying the meaning of 'Gi' among the ancient chinese philosophy and medicine such as "Hwangjenaegyeong(黃帝內經)". After that, we showed the general 'Gi' and its variations in the meaning of 'Gi' according to name and function in "Hwangjenaegyeong(黃帝內經)"and other classics of prominent historic scholars of medicine, finally trying to find out the essentials of mind-spirit[神氣] by Janggyeongak(張景岳) and original gi[元氣] by Seoryeongtae(徐靈胎).

• Korean Journal of Oriental Medicine
• /
• v.12 no.2 s.17
• /
• pp.63-73
• /
• 2006

In the original plant of Arisaematis Rhizomas, the features of external and internal shape of Arisaema amurense var. serratum $N_{AKAI}$ and A. amurense $_{MAXIM}$. are as follows. 1. In the external shape of original plant, Arisaema amurense var. serratum $N_{AKAI}$ has high stem, an oval-elliptic leaflet and a serrate leaf margin. But A. amurense $M_{AXIM}$ has a relatively low stem, an upside oval leaflet and no serrate leaf margin. 2. On the herbs character of original plant, Ansaema amurense var. serratum $N_{AKAI}$ is small in height and diameter, but A. amurense $M_{AXIM}$ is relatively large in height and diameter. 3. On the gathered herbs character of original plant, the section of Arisaema amurense var. serratum $N_{AKAI}$ is brightly white, easily spilt and strong scent. But the section of A. amurense $M_{AXIM}$ is thin yellowish brown, not easily spilt and weak scent. Also the grade of gathered herbs, both can be classified by diameter and external scent. 4. In the current herbs character, Korean and Sichuan Province products are irregullar shape and have no scent, Jilin Province products are regular shape. Also, Guangxi Province products are small size and concave in one side, Hebei Province products are irregular size and shape. 5. In internal shape of original plant, epidermal cell of Arisaema amurense var. serratum is very tight. With the except of micro difference in parenchyma cell of cortex, on the whole there are nearly no differences with A. amurense $M_{AXIM}$. Also, samely in the internal shape, according to collecting sites, epidermis exhibits a lot layer in curving state and secreting duct is developed and vascular bundle and exists between parenchyma cell of cortex. In the future, additional study is needed to distinguish herb and effect between same genus-degree of relatedness.

• Progress in Medical Physics
• /
• v.27 no.4
• /
• pp.189-195
• /
• 2016

This paper aims to verify the clinical feasibility of a custom-made film created by a laser cutting tool for End-to-End (E2E) quality assurance in robotic intensity modulated radiation therapy system. The custom-made film was fabricated from the Gafchromic EBT3 film with the size of $8^{{\prime}{\prime}}{\times}10^{{\prime}{\prime}}$ using a drawing that is identical to the shape and scale of the original E2E film. The drawing was created by using a computer aided design program with the image file, which is obtained by scanning original E2E film. Beam delivery and evaluations were respectively performed with the original film and the custom-made film using fixed-cone collimator on three tracking modes: 6D skull (6DS), Xsight spine (XS), and Xsight lung (XL). The differences between total targeting errors of the original and custom-made films were recorded as 0.17 mm, 0.3 mm, and 0.17 mm at 6DS, XS, and XL tracking modes, respectively. This indicates that the custom-made film could yield nearly equivalent results to those of the original E2E film, given the uncertainties caused by distortions during film scanning and vibrations associated with film cutting. By confirming the clinical feasibility of a custom-made film for E2E testing, it can be expected that economic efficiency of the testing will increase accordingly.

• The Journal of Korean Medicine
• /
• v.18 no.2
• /
• pp.199-213
• /
• 1997

A comparative study of influence by area between acupuncture points on hand of original acupuncture system with those of hand acupuncture system was resulted as followes 1. The influence of acupuncture points on original acupuncture system was different from those on hand acupuncture system by meridian system even though on same area or point but was similar by meridian coordination even though on different area or point. 2. The influence of acupuncture points on hand acupuncture system was almost added by those of coordinated original acupuncture system point on those of hand acupuncture system point. 3. The influence of non coordinated hand acupuncture points with several original acupuncture points was according to those of up or down point on same meridian. 4. Tung;s acupuncture system had no corelationship with other two acupuncture systems, where it has no holistic system on original princeple and Extra-points had also no corelationship, where it has no meridian system.