• The Journal of Internal Korean Medicine
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• v.18 no.2
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• pp.151-159
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• 1997

Fructus Tribuli has been used in Korea for many centuries as a therapeutic agent for headache and dizziness due to hyperactivity of the liver-yang. The effect of Fructus Tribuli on the blood pressure is not known. The purpose of this study was to determine the effect of Fructus Tribuli on blood pressure and artery rats and rabbits. 1. Fructus Tribuli exerted a dose-dependent relaxation of isolated rabbit common carotid artery. 2. Blood pressure was significantly decreased by Fructus Tribuli (10.0mg/kg) in rats.

• The Journal of Korean Physical Therapy
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• v.26 no.1
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• pp.27-32
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• 2014

Purpose: The purpose of the study was to comparison of trunk muscle activity during static standing position and standing position on therapeutic climbing wall of adult. Methods: Study subject is arbitrarily classified into 10 of experimental group and 10 control group among 20 of adult. Trunk activity measured as rectus abdominalis, external oblique, internal oblique, erector spinae. Control group maintains that center of gravity of trunk pass the front of shoulder, pelvis, knee and ankle on stable surface with putting legs apart more than shoulder width. Experimental group had static exercise on 4 by 3 meter, 90 degree of Therapeutic climbing wall. Starting position is that putting arms and legs apart more than shoulder width. In order to compare the effect of it between the groups, independent t-test was used. Results: According to the test result, significant difference between among rectus abdominalis, erector spinae the experimental groups. And external oblique, internal oblique muscle atvity is no significant difference experimental groups between among the control groups was observed. Conclusion: Trunk muscle activation is activated to standing position on the Therapeutic Climbing Wall more than static standing position.

• The Journal of Dong Guk Oriental Medicine
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• v.9
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• pp.1-23
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• 2000

Osteoporosis is a common disorder characterized by reduced bone mineral density, deterioration of the microarchitecture of bone tissue and increased risk of fracture. The aim of treatment of osteoporosis is to maintain and, ideally, to restore bone strength safely. In recent years the role of polypeptide growth factors in bone metabolism has begun to appear. It has been proposed that alterations in the expression or production of growth factor can modulate the proliferation and activity of bone forming cells. Thus, the role of structurally diverse peptides for the management and diagnosis of osteoporosis has attracted the attention of many investigators. This paper reviews numerous findings concerning the use of polypeptides, hormones, and growth factors, for the management of osteoporosis. Many of the compounds mentioned here are experimental prototypes of new therapeutic classes. Though it is unlikely that some of the compounds may ever be used clinically, development of safe and efficacious agents in each class will define the future course of therapy for osteoporosis.

• The Journal of Internal Korean Medicine
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• v.28 no.1
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• pp.193-198
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• 2007

Objective : The aim is to derive further studies evaluating the effectiveness of oriental medical treatment on advanced gastric cancer (AGC) patients. We present a case of a stage IV AGC patient who has survived over 8 years. Methods : We followed up all documents related to the patient. We prescribed to the patient HangAmDan (HAD) three times a day over five years. Abdomen CT was performed to evaluate the therapeutic efficacy. Results : The patient has survived over 8 years. Abdomen CT has shown complete regression. Conclusion : This case may give us the possibility of that oriental medical treatment offers potential benefits for patients with AGC.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.3
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• pp.27-35
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• 2013

Objectives The aim of this study was to investigate anti-inflammatory activity of Mugi-hwan (MGH) Water Extract. Methods Cells were treated with 2 ug/ml of LPS 1 hour prior to the addition of MGH. Cell viability was measured by MTS assay. The production of NO was determined by reacting cultured medium with Griess reagent. The expression of COX-2, iNOS and MAPKs was investigated by Western blot, RT-PCR. The content of level of cytokines ($PGE_2$, IL-6, in media from LPS-stimulated Raw 264.7 cells was analyed by ELISA kit. Results MGH inhibited the production of NO, $PGE_2$, IL-6 as well as the expressions of iNOS, COX-2 in the murine macrophage, RAW 264.7 cells. MGH also had suppression effects of LPS induced MAPKs activation. Conclusions These results suggest that MGH has an anti-inflammatory therapeutic potential, which may result from inhibition of MAPK phosphorylation, thereby decreasing the expression of pro-inflammatory genes.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.2
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• pp.27-38
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• 2011

Objectives: The purpose of this study is to demonstrate the therapeutic effect of oriental medical treatment on Hemophilic arthropathy. Methods: The patient was treated by Herb medicine, Acupuncture, Moxibustion, and Cupping. As a result, improvement in the ROM of joints was shown. ROM(Range of motion), Lequesne's functional index(LFI), WOMAC index and Visual analogue scale(VAS) were used to measure the progression. Results The ROM, LFI, WOMAC index and VAS were evaluated during admission. All scales improved; ROM of knee joint : $60^{\circ}$($105^{\circ}$ to $165^{\circ}$), ROM of ankle joint : $40^{\circ}$($20^{\circ}$ to $60^{\circ}$), LFI : 15 to 4, WOMAC index : 55 to 12 and VAS : 5.0 to 1.0. We also improved the patient's symptoms with oriental medical treatment. Conclusions: According to the results, oriental medical treatment is considered to be effective on Hemophilic arthropathy and further study is needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1303-1310
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• 2006

In oriental medicine, Samul-tang (SMT) has been used for the treatment of cardiovascular diseases and neuronal disorders. Here, possible effects of SMT on axonal regeneration after the spinal cord injury were examined. SMT treatment induced increases in regeneration-related proteins GAP-43, cell division cycle 2 (Cdc2) and phospho-Erk1/2 in the peripheral sciatic nerves after crush injury. Increased levels of Cdc2 and phospho-Erk1/2 were observe mostly in the gray matter area and some in the dorsomedial white matter. These increases correlated with increased cell numbers in affected areas. Moreover, axons of corticospinal tract (CST) showed increased sprouting in the injured spinal cord when administrated with SMT compared with saline-treated control. Thus, the present data indicate that SMT may be useful for identifying active components and for therapeutic application toward the treatment of spinal cord disorders after injury.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.793-799
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• 2021

Objectives: This study examined the effects of Gamisachil-tang on an anorexic patient with depression. Methods: A patient suffering from anorexia and depression was treated with Korean herbal medicine (Gamisachil-tang) for 14 days. To evaluate the therapeutic effect, we measured the daily food intake of the patient and used the Visual Analogue Scale (VAS) for anorexia. Results: Following treatment, both the patient's daily food intake of the patient and VAS score for anorexia had improved. Conclusion: These results suggest that Gamisachil-tang has a beneficial effect on both anorexia and depression.

• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.144-151
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• 2022

Objective: The purpose of this study is to report the effects of Shihogayonggolmoryo-tang on elderly delirium. Methods: A patient suffering from delirium was treated with Shihogayonggolmoryo-tang herbal therapy for 35 days. To evaluate the therapeutic effects, the Korean version of the Mini Mental State Examination (MMSE-K) and the Korean Nursing Delirium Screening Scale (nu-DESC) were used twice a week. Results: After treatment, the patient's MMSE-K score increased from 0 to 12, and the nu-DESC results decreased 4 to 0. Conclusion: These scores suggest that therapy with Shihogayonggolmoryo-tang has a positive effect on elderly delirium.

• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.152-158
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• 2022

Objective: This study addresses a case of fibromyalgia with insomnia and dry mouth. Methods: A patient diagnosed with fibromyalgia was treated with Korean medicine including herbal therapy with Guibiondam-tang-gagam, acupuncture, pharmacopuncture, moxibustion, and chuna for 16 days. To evaluate the therapeutic effects, sleeping hours, time taken to fall asleep, and surprise on waking were assessed, and a numeric rating scale (NRS) was used to monitor dry mouth. Results: After treatment, the patient's sleeping hours increased, time taken to fall asleep decreased, and the patient woke up surprised less often. The NRS score for dry mouth also decreased. Conclusion: These results suggest that Korean medicine therapies with Guibiondam-tang-gagam have a beneficial effect on insomnia and dry mouth as additional symptoms of fibromyalgia.