• Microbiology and Biotechnology Letters
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• v.37 no.3
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• pp.273-279
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• 2009

Hyungbangjihwang-Tang (HT), an Oriental herbal formula, has been known to play a role which helps to recover vigor of human in the Orient. In this study, antifungal substance (HTI) was purified from the ethyl-acetate extracts of HT by using $SiO_2$ column chromatography and HPLC, and the antifungal effects of HTI and its mode of action were investigated. By using a broth micro-dilution assay, the activity of HTI was evaluated against fungi. HTI showed antifungal activities without hemolytic effect against human erythrocytes. To confirm antifungal activity of HTI, we examined the accumulation of intracellular trehalose as stress response on toxic agents and effect on dimorphic transition in Candida albicans. The results demonstrated that HTI induced the accumulation of intracellular trehalose and exerted its antifungal effect by disrupting the mycelial forms. To understand its antifungal mode of action, cell cycle analysis was performed with C. albicans, and the results showed HTI arrested the cell cycle at the S phase in yeast. The present study indicates that HTI has considerable antifungal activity, deserving further investigation for clinical applications.

• Journal of Korean Neurosurgical Society
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• v.61 no.5
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• pp.568-573
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• 2018

Objective : Thoracic pedicles have special and specific properties. In particular, upper thoracic pedicles are positioned in craniocaudal plane. Therefore, manipulation of thoracic pedicle screws on the left side is difficult for right-handed surgeons. We recommend a new position to insert thoracic pedicle screw that will be much comfortable for spine surgeons. Methods : We retrospectively reviewed 33 patients who underwent upper thoracic pedicle screw instrumentation. In 15 patients, a total of 110 thoracic pedicle screws were inserted to the upper thoracic spine (T1-6) with classical position (anesthesiologist and monitor were placed near to patient's head. Surgeons were standing classically near to patient's body while patients were lying in prone position). In 18 patients, a total of 88 thoracic pedicle screws were inserted to the upper thoracic spine with the new standing position-surgeons stand by the head of the patient and the anesthesia monitor laterally and under patient's belt level. All the operations performed by the same senior spine surgeons with the help of C-arm. Postoperative computed tomography scans were obtained to assess the screw placement. The screw malposition and pedicle wall violations were divided and evaluated separately. Cortical penetration were measured and graded at either : 1-2 mm penetration, 2-4 mm penetration and >4 mm penetration. Results : Total 198 screws were inserted with two different standing positions. Of 198 screws 110 were in the classical positioning group and 88 were in the new positioning group. Incorrect screw placement was found in 33 screws (16.6%). The difference between total screw malposition by both standing positions were found to be statistically significant (p=0.011). The difference between total pedicle wall violations by both standing positions were found to be statistically significant (p=0.003). Conclusion : Right-handedness is a problem during the upper thoracic pedicle screw placement on the left side. Changing the surgeon's position standing near to patient's head could provide a much comfortable position to orient the craniocaudal plane of the thoracic pedicles.

• Elastomers and Composites
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• v.46 no.4
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• pp.311-317
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• 2011

The neodymium magnet inserted mold was proposed to orient magneto-responsible particles efficiently. The anisotropic magneto-rheological elastomer(MRE) was prepared using the new mold and the optimum amounts of the particles was 30 vol.%. As the orientation of particles was increased, the tensile strength of MRE was decreased, while the hardness of MRE was increased. It was found that the MRE containing 30 vol.% of magneto-responsible particles showed the maximum magneto-rheological effect. The ratio of shear modulus shift was 59% at the input current of 3 A. The transmissibility of MRE was decreased with increasing the input current and loading amounts of magneto-responsible particles. Therefore, the damping property of MRE could be improved by preparing the anisotropic MRE.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.22-22
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• 2018

Based on medicinal plant references from Vietnam, 1884 flowering plant species (194 families, 956 genera) can be used to treat 30 diseases or have 4 valuable uses such as Tranquillizer, Detoxify, Galactopoietic and Diuretic. 23 species (15 families, 18 genera) for Tranquillizer, 94 species (50 families, 79 genera) for Vaginitis, 18 species (13 families, 15 genera) for Paralytic, 6 species (6 families, 6 genera) for Obese, 60 species (28 families, 50 genera) for Flu, 63 species (37 families, 56 genera) for Eyesore, 96 species (45 families, 77 genera) for Toothache, 97 species, (50 families, 86 genera) for Detoxify, 18 species (18 families, 18 genera) for Syphilis, 80 species (50 families, 71 genera) for Asthma, 17 species (8 families, 11 genera) for HIV AIDS, 56 species (41 families, 54 genera) for Gonorrhoea, 378 species (108 families, 56 genera) for Dysentery, 31 species (22 families, 29 genera) for Galactopoietic, 131 species (69 families, 116 genera) for Diuretic, 11 species (9 families, 9 genera) for Mump, 737 species (129 families, 626 genera) for "Snack bite", 23 species (18 families, 22 genera) for Urolithiasis, 134 species (56 families, 122 genera) for Malaria, 462 species (113 families, 323 genera) for Rheumatism, 55 species (34 families, 49 genera) for Diabetes, 87 species (42 families, 70 genera) for Heart and blood pressure diseases, 70 species (46 families, 63 genera) for Haemorrhoids, 21 species (16 families, 20 genera) for Cancer, 42 species (27 families, 38 genera) for Gastritis, 154 species (66 families, 129 genera) for Hepatitis, 5 species (5 families, 5 genera) for Keratitis, 81 species (42 families, 75 genera) for Sore throat, 11 families (9 families, 11 genera) for Encephalitis, 72 species (41 families, 66 genera) for Nephritis, 10 species (6 families, 8 genera) for Sinusitis, 22 species (17 families, 20 genera) for Sterile, 19 species (14 families, 17 genera) for Cirrhosis, 3 species (3 families, 3 genera) for Brain hemorrhage. Each species can be used to treat some diseases. The information of species can be used to orient researches fast and effectively.

• Journal of Acupuncture Research
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• v.21 no.1
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• pp.99-110
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• 2004

Objective: The purpose of this study was to examine the different effects on labor pain, length of delivery time, and hemoglobin for primipara women treated by San-Yin-Jiao(SP-6) acupressure of 15 minutes or 30 minutes. Methods: The design of this study was a randomized clinical trial with two experimental groups and one control group, the participants included primiparas who underwent vaginal delivery. Data were collected using a structured questionnaire consisting of general characteristics with a subjective labor pain scale with VA.S, and length of delivery time and hemoglobin were collected in the medical record. Data was analyzed using descriptive statistics, x2- test, t-test, and ANCOVA. Results: There was statistically significant lower labor pain in the group of 30 minutes SP6 acupressure than the control group(t=7.733, p=.007), and there was statistically significant short length of delivery time in the group of 15 minutes SP6 acupressure than the control group(t=-2.230, p=.030). Conclusions: Even though we could not found a consistent effect with the SP6 acupressure, It was found that there was effect on shortening length of delivery time by 15 minutes of SP6 acupressure or lessening labor pain by 30 minutes of SP6 acupressure without risk of blood loss. It is necessary to replicate the study with a larger number of participants to find a consistent result.

• The Korea Journal of Herbology
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• v.27 no.4
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• pp.45-51
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• 2012

Objectives : WHW is a polyherbal medicine for the treatment of chronic renal failure (CRF). WHW previously reported various biological property such as anti-inflammation, anti-oxidation and anti-renal fibrosis in CRF. This study aimed to investigate the anti-apoptotic effect of WHW on staurosporin(SSP)-induced apoptosis in canine kidney epithelial cells (MDCK). Methods : MDCK cells were treated with different concentrations of WHW (0.1, 0.2, 0.5 and $1mg/m{\ell}$) for 1 h, and then induced apoptosis by treatment of SSP ($1{\mu}M$) for 24 h. Cell viability was measured by WST-1 assay. The expression of apoptotic proteins such as caspase-3, Bax and Bcl-2 was determined by Western blot. Caspase-3 activity and ROS levels were also measured by their commercial available assay kits. Cell apoptosis was observed by Hoechst and DNA fragmentation. Results : WHW significantly increased the cell viability on SSP-treated MDCK cells. WHW inhibited SSP-induced expression of apoptotic proteins such as caspase-3 and Bax, and significantly decreased caspase-3 activity in MDCK cells. WHW significantly decreased SSP-induced production of ROS, and suppressed SSP-induced chromatin condensation and DNA fragmentation in MDCK cells. Conclusions : These results suggest that WHW has an anti-apoptotic effect in renal cells through suppressing the expression of apoptotic proteins, ROS production and DNA damages.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.628-641
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• 2012

This research investigates a dynamic mechanism underlying the co-evolution between network and space by applying hype-curve model, typical phenomenon which shows how new technologies and ideas initially adapted in the society. This study analysis the knowledge intensive industry of digital contents using social network analysis (SNA) in terms of structural, spatial, and temporal aspects, year of 2000, 2005, and 2010 focused on Seoul area. First of all, network and space establish 'inter-feedback' as a result of evolution and differentiation process. Second, it happen temporal 'delay' through the learning process stage of 'peak of inflated expectation' and 'trough of disillusionment.' As a result, Seoul develops with the technology commercialized-orient strategy affect government policy. This trend changes to technology-oriented development in Seoul area in the late of 2000 established 'self-organization' with geographical proximity organizations through learning process.

• International Journal of Ocean System Engineering
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• v.1 no.2
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• pp.95-101
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• 2011

Perforated plates with cutouts (or holes) are widely used in structural members. These cutouts provide stress concentration in plates. Extensive studies have been carried out on stress concentration in perforated plates, which consider cutout shapes, boundary conditions, bluntness of cutouts, and more. This study presents stress concentration analyses of perforated plates with not only various cutouts and bluntness but also different cutout orientations. Especially, the effect of cutout orientation on stress concentration is emphasized since structural members have become more complicated recently. To obtain stress concentration patterns, a finite element program, ANSYS, is used. For the designated goal, three parameters are considered as follows: the shapes of polygonal cutouts (circle, triangle, and square), bluntness (a counter measure of radius ratio, r/R), and rotation of cutouts (${\theta}$). From the analyses, it is shown that, in general, as bluntness increases, the stress concentration increases, regardless of the shape and rotation. A more important finding is that the stress concentration increases as the cutouts become more oriented from the baseline, which is the positive horizontal axis (+x). This fact demonstrates that the orientation is also a relatively significant design factor to reduce stress concentration. In detail, in the case of the triangle cutout, orienting one side of the triangle cutout to be perpendicular to the applied tensile forces is preferable. Similarly, in the case of the square cutout, it is more advantageous to orient two sides of square cutout to be perpendicular to the applied tensile force. Therefore, at the design stage, determining the direction of a major tensile force is required. Then, by aligning those polygon cutouts properly, we can reduce stress concentration.

• Journal of the Korean Society of Food Science and Nutrition
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• v.16 no.2
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• pp.83-86
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• 1987

Lipids extracted and purified from Herbs Capsellae leaf ana root were studied, To investigate those, silicic acid column chromatography, TLC, GLC was used for analysis of lipids and Fatty acids composition. Following results were obtained. 1. From result of total lipid classes in Herba Capsellae leaf and root, NL were obtained 62.6%, 58.5% respectly. GL 20.8%, 17,8%. PL 16.6%, 23.7%, respectively. 2. Among the NL in Herba capsellae leaf and root, TG were predominant 77.5%, 80.3%, respectly. SE 9.2%, 8.4%. FFA 4.8%, 3.4%. 1.2-DG 4.1%, 3.6%. FS 2.2%, 2.2%. and 1, 3-DG 1.3%, 1.0%, in turn. 3. The major fatty acids in the lipid classes were linoic acid, palmitic acid, oleid acid, in all. And total unsaturated fatty acid was NL 78.0%, GL 66.6%, and PL 75.2% in Herbs capsellae leaf, and NL 66.1% GL 63.6% and PL 61.2% in Herbs capsellae root.

• Journal of the Korean Society of Costume
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• v.3
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• pp.29-46
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• 1980

The purpose of this thesis is to find out how the upper garment styles in the Ancient East and est had been influenced with each other. Analytical studies conclude the fellowing findings: 1) Upper garment styles in the feat Asia and the Egypt already highly developed in 28th century B.C. and show us the original style of the wrap-over to the left and that of the round neckline(曲領). Upper garment of the open in the center front shown in Babylonia in 18th century B.C. had been inherited to the caftan of the Hebrew and later succeeded to the Persia. 2) The tunic styles of the round neckline, the wrap-over to the left and the open in the cotter front, which were the basic styles of the upper garment, had teen widely accepted to the central Asia and the East Asia, as well as the Northern Europe, from the West Asia. 3) The styles of the wrap-over to the right originated from China since it had begun to show in the Shang Dynasty(商代, 殷代). 4) The East and the West costumes had been very much intermixed in 4th century B.C. Alexander the Great of Macedoria in 4th century B.C. expanded his territory to the central Asia and built up the Bacteria, when the most western civilization had been greatly transmitted to the Orient. Meanwhile the tunic being clad in the West and Central Asia began to be worn by soldiers in the period of the Warring States in China (326-299 B.C.) and afterwards worn even by civil officials since the age of the T'ang Dynasty of China. 5) The Upper garments of the open in the center front, the wrap-over to the right, the wrap-over to the left and the round neckline were found in Korea, which mean that the upper garment styles in the Ancient Korea were intermixed of the factors from the West Asia, the central Asia and the East Asia. 6) The styles of costume in the East Asia were influenced by the West Asia through the central Asia. The upper garment styles Europe were also influenced by the West Asia. Thus the upper garment styles in the Ancient East and West had been mutually affected with each other.