• Journal of Korea Society of Industrial Information Systems
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• v.14 no.5
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• pp.75-82
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• 2009

It is possible that gain good effect for saving electric charges by power-saving education to organizer, instead of buying new energy saving computer in the company, school and public organization. But this kind of education needs time very much. And power management system for controling whole computer of organizer is released, but it is hard to set up. In this paper we prevent computers which do not have power shutdown software, from obtaining IP address by DHCP. So we induce organizer to setup power shutdown software.

• KSCI Review
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• v.1 no.2
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• pp.1-7
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• 1995

• Journal of The Korean Association of Information Education
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• v.15 no.2
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• pp.189-199
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• 2011

The purpose of this study is to verify the effects of the advance organizer in programming class on elementary school students' logical thinking ability and self-efficacy. We developed our teaching-learning materials of programming for this purpose, Further, they are applied to the elementary school, and their effects are analyzed. Fourth grade students in elementary school were selected for the experiments of this study, For comparison, they were divided into a control group who taught by a traditional programming teaching method and an experimental group who taught by our advance organizer programming class. As a result, through before-and-after t-verifications performed on the experimental group and the control group respectively, we found statically significant differences between the two groups, and the effectiveness of our new programming teaching method was proved in both learner's self-efficacy and logical thinking ability.

• Environmental Mutagens and Carcinogens
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• v.10 no.2
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• pp.135-145
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• 1990

Silver-binding nucleolar organizer regions (Ag-NORs)염색법을 이용하여 in vivo 및 in vitro에서 발암과정과 관련된 세포증식능을 검토하였다. A/J마우스에 benzo (a) pyrene을 투여하여 유발된 폐선종, 폐선암 및 Sprague-Dawley랫트에 dimethylbenz (a) anthracene투여에 의해 발생된 유선의 선암세포에서 Ag-NORs의 염색상태를 정상 조직과 비교하여 또한 정상마우스 섬유모세포인 NIH3T3에서의 Ag-NORs의 수 및 DNA 증식 억제물질인 caffeine에 의한 변화를 관찰하였다. 은친화성 NOR과련 단백질은 핵내 흑색의 반점으로 나타났으며 정상 폐조직의 세포당 Ag-NORs 수치는 0.87+0.01였으며 양성종양인 폐선종세포 및 악성종양인 폐선암세포에서는 각각 2.33+0.02, 2.56+0.45 정상 유선조직의 세포당 Ag-NORs수치는 1.21+0.16였으며 악성종양인 선암세포는 3.91+0.11로써 종양성 병변에서 유의한 증가를 보였다 (P<0.005).

• 대한두경부종양학회:학술대회논문집
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• 1993.11a
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• pp.263.2-263.2
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• 1993

• Journal of The Korean Association of Information Education
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• v.14 no.2
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• pp.241-251
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• 2010

In knowledge-based society, various forms of visible and invisible works are produced and published. As production and distribution of those works are increased, importance and value of copyright are gradually emerged. In the light of importance, students must learn and understand the concept and the right use of copyright as early as possible. Scales that students experience in the introduction stage of the class take the role of Advance Organizer. Through these scales, students can combine concept of copyright into their existing recognition structure and are interested in study contents. According to test results, it is concluded that the proposed system is very useful to enhance copyright consciousness for students.

• Journal of Yeungnam Medical Science
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• v.8 no.2
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• pp.63-69
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• 1991

Nucleolar organizer regions (NOR) are loops of ribosomal DNA(rDNA) which are transcribed by RNA polymerase I. They produce ultimately ribosome and protein. Thus they are believed to reflect nuclear activity. We applied silver colloid staining technique to human glioma to examine relationship between the mean number of Ag-NOR and histopathological grading. The mean number of Ag-NOR(${\pm}$ S.E of the mean)were $1.17{\pm}0.07$ in normal brain, $1.53{\pm}0.25$ in astrocytoma, $2.37{\pm}0.71$ in malignant astrocytoma, and $2.88{\pm}0.41$ in glioblastoma multiforme. And there was a statistically significant difference among these. The results show that Ag-NOR technique is a rather simple and rapid method and will become a helpful tool for estimation of the proliferative potential of glioma.

• Molecules and Cells
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• v.41 no.2
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• pp.110-118
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• 2018

The objective of this study was to induce the production of isthmic organizer (IsO)-like cells capable of secreting fibroblast growth factor (FGF) 8 and WNT1 from human embryonic stem cells (ESCs). The precise modulation of canonical Wnt signaling was achieved in the presence of the small molecule CHIR99021 ($0.6{\mu}M$) during the neural induction of human ESCs, resulting in the differentiation of these cells into IsO-like cells having a midbrain-hindbrain border (MHB) fate in a manner that recapitulated their developmental course in vivo. Resultant cells showed upregulated expression levels of FGF8 and WNT1. The addition of exogenous FGF8 further increased WNT1 expression by 2.6 fold. Gene ontology following microarray analysis confirmed that IsO-like cells enriched the expression of MHB-related genes by 40 fold compared to control cells. Lysates and conditioned media of IsO-like cells contained functional FGF8 and WNT1 proteins that could induce MHB-related genes in differentiating ESCs. The method for generating functional IsO-like cells described in this study could be used to study human central nervous system development and congenital malformations of the midbrain and hindbrain.

• Journal of Animal Science and Technology
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• v.45 no.5
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• pp.695-702
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• 2003

Nucleolus Organizer Regions (NORs) are the specific chromosome sites where ribosomal genes are located and highly expressed. We have applied the AgNOR staining to identify the distribution of NORs in the chromosomes of Korean Cattle. We have also studied the NORs pattern on the cells originated from different breeds, tissues and sex. Peripheral blood from forty-four Korean Cattle and Holstein was cultured for chromosme preparation. The fibroblast culture from biopsied ear skins was also conducted for chromosome analysis. The distribution of NORs was analyzed by sequential Ag staining and G-banding on metaphases of the cells. In Korean Cattle, the NORs are localized on the telomeres of the five chromosome pairs number 2, 3, 4, 11 and 28. The number of NORs per metaphase ranged from 2 to 10 giving a mean value of 5.6. The number of NORs per cell varied among individuals and cells within same individual. The size of NORs also differed in NO-chromosomes. The number of NORs was significantly different between Korean Cattle and Holstein, fibroblasts and lymphocytes, and male and female. However, the distribution and frequency of NORs were similar among the cells regardless of breeds, tissues, and sex.

• Tuberculosis and Respiratory Diseases
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• v.42 no.4
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• pp.513-521
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• 1995

Background: Nucleolar organizer regions(NORs) are chromosomal segments encoding for ribosomal RNA and associated with argyrophilic nonhistone protein. Ribosomal RNA genes ultimately direct ribosome and protein synthesis, and it has been suggested the numbers of NORs detected in the cell may reflect nuclear and cellular activity. This study was performed to evaluate the applicability of AgNORs to the diagnosis of squamous cell carcinoma of the lung. Method: The one step silver methods(AgNORs) was used to stain NORs in the routinely processed, formalin fixed, paraffin embedded sections of 36 cases of squamous cell carcinoma of the lung obtained by surgical resection of primary tumor. In each specimen, 100 tumor cells and 100 normal cells adjacent to the tumor chosen at random were examined under an oil immersion lens at a magnification of ${\times}1000$. The mean number of AgNORs per nucleus was calculated for each specimen. Results: The mean number of AgNORs per nucleus(mAgNORs) of normal bronchial epithelium and squamous cell carcinoma of the lung was $1.74{\pm}0.25$ and $4.05{\pm}0.80$, respectively. The difference of mAgNOR between normal and tumor tissue was statistically significant(p<0.001). There was no statistical difference among tumors of different stages. The difference of mAgNOR between normal and tumor tissue was statistically significant in each TNM stage(p<0.05). Conclusion: Mean AgNOR count may be used as a useful marker for the differential diagnosis of benignancy and malignancy, and proliferative activity of the cell in squamous cell carcinoma of the lung. But there was no statistical difference in mean AgNOR count among tumors of different surgical stages. Further studies for the application of mAgNORs to the diagnosis of other histologic types and cytologic specimens of the lung cancer are needed.