• Korean Journal of Veterinary Research
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• v.58 no.2
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• pp.87-94
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• 2018

This study assessed the effects of Weissella cibaria (W. cibaria) CMU on oral health in male and female beagles (n = 18) by measuring oral malodor and periodontal disease-related parameters (calculus, plaque, and gingivitis indices). Oral malodor and indicators of periodontal disease were assessed in five treatment groups: negative control (scaling and 0.24 mg of maltodextrin, n = 3), positive control (0.24 mg of maltodextrin, n = 3), and W. cibaria CMU groups (each n = 4) at low (CMU-L, $2{\times}10^7$ colony forming unit [CFU]), medium (CMU-M, $2{\times}10^8CFU$), and high (CMU-H, $2{\times}10^9CFU$) concentrations. After feeding with W. cibaria CMU for 6 weeks, total volatile sulfur compound concentrations in the CMU-L ($2.0{\pm}1.04ng/10mL$), CMU-M ($2.4{\pm}1.05ng/10mL$), and CMU-H ($2.6{\pm}1.33ng/10mL$) groups were significantly lower than in the positive control group ($3.2{\pm}1.65ng/10mL$). Also, CMU-L ($1.4{\pm}0.83ng/10mL$) and CMU-H ($1.9{\pm}1.14ng/10mL$) groups had methyl mercaptan levels lower than that in the positive control group ($2.4{\pm}1.21ng/10mL$) at week 2. The plaque index was significantly lower in the CMU-H group ($4.5{\pm}0.28$) than in the positive control group ($5.9{\pm}1.08$) at week 6. W. cibaria CMU could be useful as a novel oral hygiene probiotics for reducing volatile sulfur compounds production and inhibiting plaque growth in companion animals.

• Journal of Oral Medicine and Pain
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• v.32 no.3
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• pp.273-281
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• 2007

Zinc compounds have been used in various fields - cosmetics, medicine, and dentistry -because of its effective functions to human tissues or organs. Especially, it is well known that zinc has many biologic effects in oral cavity. Zinc ion can affect various oral microorganisms, resulting in reduction of oral bacteria, dental plaque, and dental caries. Also, zinc ion has an ability to reduce amounts of oral anaerobic bacteria and oral VSC and can reduce oral malodor. The author summarized the characteristics and toxicity of zinc, several forms of zinc compounds applied in human tissues, and reviewed biologic effects of Zinc in oral cavity (anti-bacterial effects, anti-plaque effects, anti-caries effects, and anti-VSC effects of zinc). Because of many advantages of zinc in oral cavity, it can be concluded that application of zinc compound to various oral diseases will be extended and activated, and promising.

• The Journal of Korean Medicine
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• v.31 no.4
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• pp.115-128
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• 2010

Objectives: The aim of this study was to investigate deodorizing effectsof medicinal herbs (Mume Fructus, Eriobotryae Folium, Acanthopanacis Cortex, Angelicae Dahuricae Radix) for development of a gargle solution. Methods: 1. The antimicrobial effects of medicinal herbs were evaluated with the minimal bactericidal concentration (MBC) and the change of the number of viable cells in the herb extracts(1%) for 48 hrs against P. gingivalis 2561 and Pr. intermedia ATCC 25611. 2. Deodorizing activity of each herb and Garglin $Mint^{(R)}$gainst methyl mercaptan were analyzed by gas chromatography (GC). 3. We used the malodor modeling of the salivary sediment system with a Halimeter. 4. In the preliminary clinical study, the baseline concentration of VSC in the oral cavity of each subject was measured by Halimeter. Subjects would gargle for 30 seconds with cysteine. After 4 minutes subjects would gargle for 30 seconds with Garglin and herb extracts (2%). Subsequently, concentration of VSC were measured at 0, 4, 8, 12 and 20 minutes. Results: 1. MBC of Mume Fructusfor P. gingivalis 2561 was determined to be <1% and MBCs of Eriobotryae Folium for P. gingivalis 2561 and Pr. intermedia ATCC 25611 were determined to be <2% and <1%, respectively. Mume Fructus (1%) completely suppressed the P. gingivalis cell viability from 5 hrs and Eriobotryae Folium (1%) completely suppressed the Pr. intermedia cell viability from 48 hrs. 2. In GC analysis, deodorizing activities were 91.54% with Mume Fructus, 87.97% with Eriobotryae Folium, 100% with Acanthopanacis Cortex, 72.36% with Angelicae Dahuricae Radix and 40.54% with Garglin $Mint^{(R)}$. 3. In malodor modeling of the salivary sediment system, each of the medicinal herbs had significantly inhibitory effect on malodor formation (p<0.05). 4. In the preliminary clinical study, the concentration of VSC of the herb groups was significantly lower than of the control group, but not in Garglin $Mint^{(R)}$. Conclusions: Mume Fructus, Eriobotryae Folium, Acanthopanacis Cortex and Angelicae Dahuricae Radixhave deodorizing activities and potential as an effective mouthwash against oral malodor.

• Journal of Oral Medicine and Pain
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• v.49 no.1
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• pp.5-11
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• 2024

Halitosis is defined as a nasty odor emanating through the mouth and is primarily related to the enhanced concentration of volatile sulfur compounds (VSCs). VSC measurements have been commonly used for experimental comparison and clinical diagnosis. As quantitative methods for comparative analyses of oral malodor, gas chromatography devices have been most commonly used to quickly and easily determine the concentration of several gas components of VSCs, which are agents primarily responsible for halitosis. The concentrations of VSCs fluctuate dynamically depending on contributing factors, including various oral/systemic conditions, intake of medicine and food/drink, oral hygiene, and even routine daily activities. Therefore, the exact analysis of VSCs requires the appropriate standardization of not only exact measurement techniques but also participant conditioning with scientific considerations. Thus, this paper describes the experimental standardizations commonly recommended in previous literature and their scientific background.

• Journal of Korean society of Dental Hygiene
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• v.15 no.4
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• pp.671-677
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• 2015

Objectives: The purpose of the study was to examine the influencing factors of self-reported dry mouth in the employees in social welfare facilities. Methods: A self-reported questionnaire was completed by 260 employees in social welfare facilities from January 5 to 30, 2015 by convenience sampling method. Except 25 incomplete answers, 215 data were analyzed by t test, one way ANOVA, Pearson's correlation coefficient analysis, and multiple linear regression analysis using SPSS 180. program. The questionnaire consisted of general characteristics of the subjects, health-related characteristics, whole body dryness and self-reported dry mouth. The oral health-related quality of life was measured by five point Likert scale, and a higher score indicated a lower quality of life. Results: The self-reported dry mouth in the employees in the social welfare facilities varied by the general health status, stress, oral health status and oral malodor. The self-reported dry mouth was closely related to the quality of life and the four subfactors including dryness of skin, eye, lip and nasal mucosa. The quality of life had the influence on the self-reported dry mouth, nasal mucosa dryness, eye dryness, and oral malodor in order. Conclusions: The self-reported dry mouth was closely related to whole body dryness and the quality of life. It is necessary to develop the quality of life improvement programs that prevent and manage the dry mouth and whole body dryness in the employees in the social welfare facilities.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.252-259
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• 2004

Objectives : Halitosis is a common human condition, exact pathophysiological mechanisms of which are unclear. This study, which investigates halitosis patients' characteristics and their related factors, was done with intent to establish a foundation for the Oriental Medical treatment of halitosis. Methods : 329 patients were surveyed by reviewing medical charts and questionnaires from the East-West Halitosis Clinic of Kyunghee Medical Center from May 1, 2001 to December 31, 2002. Sex, age, illness duration, coating on the tongue, postnasal drip, globus pharyngeus, indigestion, condition of feces, halimeter measurements and results of the salivary scans were analyzed. Results : The thick and yellowish coating on the tongue was not a major cause of halitosis in the patients studied. Among the halitosis patients, 21.6% complained of postnasal drip, 15.6% of globus pharyngeus, 37.4% of indigestion, and 23.8% of diarrhea or constipation, suggesting the possibility of extra-oral origin in oral malodor. Conclusions : This study suggests that, when treating halitosis patients, intra-oral causes of halitosis aside, Oriental Medical treatments such as solving qi-stasis(氣鬱), augmenting deficiency of the spleen qi(碑氣虛) and treating gastric fever(胃熱) constitute effective management for oral malodor patients.

• Journal of Korean society of Dental Hygiene
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• v.9 no.2
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• pp.165-178
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• 2009

The purpose of this study was to provide basic information for improving oral health and dental hygiene through comprehensive dental hygiene care. The subjects in this study were 54 patients who had been treated for 4 weeks in clinic of the Dental Hygiene Department of G University under comprehensive dental hygiene control and care and measured their oral condition, intensity of oral malodor, Simplified Oral Hygiene Index (S-OHI), and Modified Personal Hygiene Performance Index (PHP-M), and surveyed their oral health behavior and oral health consciousness. The results of the study were as follows: 1. The intensity of malodor decreased by 16.49ppb from 75.33ppb on the first visit to 50.84ppb on the last visit when the comprehensive dental hygiene care had been finished. 2. As to change in S-OHI according to gender between the first visit and the last visit for comprehensive dental hygiene care, S-OHI decreased from 2.89 on the first visit to 1.16 on the last visit, and the difference was statistically highly significant. 3. As to change in PHP-M index by tooth according to gender and age between the first visit and the last visit, PHP-M index of the first 6 teeth decreased very significantly from 0.50 on the first visit to 0.34 on the last visit. 4. As a whole, significant improvement was observed in every tooth. According to gender and age, PHP-M index for Tooth No. 26, 36 and 32 decreased significantly in men and women, and those aged under 30 and those aged 30 or over, but for Tooth No. 13 and 15 and 44 it decreased significantly only in men and those aged 30 or over, and for Tooth No. 44 only in men. As presented above, the oral health behavior and oral health consciousness of the visitors to the oral prophylaxis practice room are very important, and it is necessary to enhance their interest in and knowledge of how to improve oral health. Furthermore, comprehensive dental hygiene care required for improving the visitors' oral health.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.2
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• pp.187-193
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• 2014

Dental caries are one of the most common oral diseases and Streptococcus mutans (S. mutans) plays an important role in the initiation and progression of dental caries. Oral malodor is primarily the result of microbial metabolism such as Porphyromonas gingivalis (P. gingivalis) that produce volatile sulfur compounds (VSCs), causing oral malodor. Prevotella intermedia (P. intermedia) is known as typical periodontopathic bacteria, and periodontal disease is chronic inflammatory disease that leads to damage of gingival connective tissue and alveolar bone, eventually loss of teeth. In this study, we investigated antimicrobial effect of mouthwash containing cetylpyridinium chloride (CPC), sodium fluoride (NaF), green tea water extract and pine needles water extract against cariogenic and periodontopathic bacteria sucn as S. mutans, P. gingivalis and P. intermedia. As a result, the reduction ratios of S. mutans and P. gingivalis were 4.00 Log and 4.68 Log reduction for 30 s, and P. intermedia were 2.40 Log reduction for 30 s and 2.70 Log reduction for 60 s. Dentocult SM Strip mutans (SM Strip) provides easy detection of visual data showing a significant inhibition on S. mutans. In conclusion, we expected that mouthwash containing CPC, NaF, green tea water extract and pine needles water extract could help preventing the dental disease like dental caries and oral malodor.

• Journal of the Korea Convergence Society
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• v.9 no.4
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• pp.99-110
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• 2018

The data were collected from 171 physiologic malodor patients diagnosed in KUMC halitosis control clinic between 2008 and 2016. We selected 11 independent variables and 3 dependent variables, then planned to extract some convergent common factors affecting their physiologic malodor. We thought that those extracted convergent common factors could be utilized when preparing the contents of oral malodor preventive program. We used multiple regression analysis and path analysis method, for the analysis of influence of 11 independent factors to three salivary dependent factors(resting salivary flow rate, salivary buffering capacity, salivary precipitation rate). We have presented the physiologic malodor patients' chracteristics by descriptive statistical analysis, and also statistically analysed convergent common factors influencing directly or indirectly to their three dependent factors. We could reason that the sex, the character, the intake habit of breakfast, and the regular food intake habit could affect resting salivary flow rate, salivary buffering capacity and salivary precipitation rate.

• Journal of Korean society of Dental Hygiene
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• v.10 no.4
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• pp.607-616
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• 2010

Objectives : This study was performed to enhance a rate of Using oral clinic and to search related factors of using oral clinics. Methods : The subjects of the study were 74,698 subjects who answered to the 2007 korea Youth Risk Behavior Web-based survey. Answers of 73,836 subjects were used for the final analysis. We used spss of version 12.0. This study conducted a Chi-square test to identify using oral clinics rate according to characteristics of subjects and a multivariate logistic regression analysis to identify whether they are independently significant. Results : Tooth scaling experiences were responded by 10,060 subjects(25.6%). Grade and metropolis, economic level had significant associations with using oral clinic experiences. The rate of using oral clinic showed significant difference in point, depending on general characteristics. Their oral health showed significant difference in point between using oral clinic experience and non-experience groups. According to the multiple logistics regression analysis whose significant independent variables were sex, grade, metropolis, economic level, blooding gum, tooth brushing, oral malodor. Conclusions : The policy is needed to prevent economic constraints from worsening oral health by supporting the poor. And our government should eventually prepare a public relation program suitable for public.