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http://dx.doi.org/10.15230/SCSK.2014.40.2.187

Antimicrobial Effect of Mouthwash against Streptococcus mutans by Visual Staining Method  

Park, Taehun (Amorepacific Corporation R&D Center)
Cho, Jeong Hun (Amorepacific Corporation R&D Center)
Sung, Youngeun (Amorepacific Corporation R&D Center)
Cho, Jun-Cheol (Amorepacific Corporation R&D Center)
Shin, Kyeho (Amorepacific Corporation R&D Center)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.40, no.2, 2014 , pp. 187-193 More about this Journal
Abstract
Dental caries are one of the most common oral diseases and Streptococcus mutans (S. mutans) plays an important role in the initiation and progression of dental caries. Oral malodor is primarily the result of microbial metabolism such as Porphyromonas gingivalis (P. gingivalis) that produce volatile sulfur compounds (VSCs), causing oral malodor. Prevotella intermedia (P. intermedia) is known as typical periodontopathic bacteria, and periodontal disease is chronic inflammatory disease that leads to damage of gingival connective tissue and alveolar bone, eventually loss of teeth. In this study, we investigated antimicrobial effect of mouthwash containing cetylpyridinium chloride (CPC), sodium fluoride (NaF), green tea water extract and pine needles water extract against cariogenic and periodontopathic bacteria sucn as S. mutans, P. gingivalis and P. intermedia. As a result, the reduction ratios of S. mutans and P. gingivalis were 4.00 Log and 4.68 Log reduction for 30 s, and P. intermedia were 2.40 Log reduction for 30 s and 2.70 Log reduction for 60 s. Dentocult SM Strip mutans (SM Strip) provides easy detection of visual data showing a significant inhibition on S. mutans. In conclusion, we expected that mouthwash containing CPC, NaF, green tea water extract and pine needles water extract could help preventing the dental disease like dental caries and oral malodor.
Keywords
Dental caries; Mouthwash; Streptococci mutans; Antimicrobial effect; Dentocult SM Strip mutans;
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