• 한국미생물·생명공학회지
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• 제21권6호
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• pp.615-621
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• 1993

In order to maximize the riboflavin production by a mutant strain Ashbya gosspyii, the optimization of medium and fed-batch fermentation were performed. As carbon sources, glucose and soybean oil were necessary for the riboflavin overproduction. Optimal concentrations of glucose and soybean oil in the flask cultures were found to be 3.0% and 0.5%, respectively, in a complex medium containing corn steep liquor(CLS) 1%. Among the various organic nitrogen sources tested, CSL was the most effective one both for the cell growth and riboflavin overproduction.

• 한국항공우주학회지
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• 제30권6호
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• pp.7-13
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• 2002

본 논문에서는 새로운 형태의 혼합형 유전 알고리즘을 제안하고 성능을 검증한 후 30kW 피치제어 가변 풍력발전시스템의 블레이드 설계와 피치제어 최적화에 적용하여 주어진 Weibull 분포함수에서 동력을 최대화하는 최적의 블레이드 시위 및 비틀림각의 분포와 작동범위내에서 동력을 일정하게 유지하기 위한 최적의 피치각을 결정하였다.

• Journal of Microbiology and Biotechnology
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• 제19권7호
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• pp.690-697
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• 2009

In the present study, production of compactin by Penicillium brevicompactum WA 2315 was studied. In the first step, various precultural parameters were studied by substituting one factor at a time. Subsequently, the effect of maltodextrin DE 18 on compactin production was studied. The optimized parameters gave maximum compactin production of 850 ${\mu}g/gds$as compared with 678 ${\mu}g/gds$before optimization. Statistical study was performed to further improve the production and develop a robust model. An improved yield of 950 ${\mu}g/gds$was obtained using the conditions proposed by the experimental model. The present study emphasizes the importauce of precultural and nutritional parameters on the production of compactin, and further confirms the usefulness of solid-state fermentation for the production of industrially important secondary metabolites. It also confirms that complex nitrogen sources such as oil cakes can be used for the production of compactin.

• Mycobiology
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• 제37권3호
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• pp.211-214
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• 2009

An actinomycete strain was isolated from northern part of Bangladesh and identified as a new Streptomyces species on the basis of its morphological, biochemical, cultural characteristics and 16S rRNA data. Attempts were made to optimize the culture conditions for the production of antimicrobial metabolites by this strain. Antimicrobial metabolites production was started after 7 days of incubation of culture broth and reached its maximum levels after 10 days and thereafter gradually decreased. The maximum production of antimicrobial metabolites was obtained when the culture medium pH was adjusted to 8. The optimum temperature for antimicrobial metabolites production was $39^{\circ}C$, indicated the new strain as mesophilic organism. Basel medium supplemented with glucose and yeast extract as carbon and nitrogen sources, respectively, was proved to be the best for the production of bioactive metabolites. Maximum production of bioactive metabolites was when NaCl concentration was 1% and among different minerals tested, $K_2HPO_4$ and NaCl showed positive influence on antibiotic production by the strain.

• 한국콘텐츠학회논문지
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• 제19권12호
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• pp.565-572
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• 2019

생산설비의 적절한 조합을 통한 생산 라인의 최적화는 국내 폴리에스터 산업의 경쟁력 강화를 위해 중요한 과제다. 본 연구의 목적은 폴리에스터 생산 라인의 최적화를 위해 생산 설비의 조합에 대한 우선순위를 평가하는 방법을 제시하고, 이를 통해 최적의 생산 라인 구성 방안을 도출하는데 있다. 이를 위해 폴리에스터 생산라인의 평가에 필요한 요소들을 도출하고, 이를 활용한 계층분석절차를 제시하였다. 이 방법을 활용하여 폴리에스터 생산라인 평가를 위한 요소들에 대한 가중치를 도출하였으며, 검토 중인 실제 생산라인들에 대한 우선순위와 그 시사점을 제시하였다.

• Korean Chemical Engineering Research
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• 제52권5호
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• pp.564-573
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• 2014

이 연구는 벤젠과 프로필렌의 기상반응을 통해 쿠멘을 생산하는 쿠멘 생산 공정의 경제성 최적화에 대한 것이다. 최적화의 목적함수는 제품 판매 이득에서 자본비용, 유틸리티 비용, 원료 비용을 뺀 연간 조업이득이고, 설계변수는 6개이다. 설계변수의 변화에 따른 조업이득의 계산을 위해 Unisim Design과 Matlab을 연동하였다. 최적화는 3단계로 수행되었다. 설계변수를 샘플링한 후 조업이득 데이터를 얻고, 이 데이터로부터 설계변수와 조업이득의 관계를 추정 모델로 표현하고, 이 모델을 이용하여 최적화하였다. 추정모델로는 반응표면법에서 사용되는 2차 회귀 다항식과 비선형 모델인 support vector regression을 비교하였다. 설계변수의 샘플링 방법으로는 중심합성계획과 Hammersley 순차 추출법을 비교하였다. 각각 얻어진 모델을 이용한 최적화 결과, 추정방법으로는 SVR이, 샘플링 방법은 Hammersley 순차추출법이 더 정확하였다. 최적화된 조업이득은 연간 17.96 MM$로, 기준 조건에서의 연간 16.04 MM$에 비해 12% 증가하였다.

• Journal of applied mathematics & informatics
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• 제41권1호
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• pp.215-228
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• 2023

The ready-made garments (RMG) have been making a crucial contribution about of 81% of total export and 12.36 % of total GDP of the country which is now the single biggest export earner for Bangladesh. The cheap production cost is the key important factor to explore this RMG sector. But these RMG sector is running on the basis of intuition based decisions. Though they are making profit it is not optimal. In this study, a deterministic model is developed to help the RMG to minimize the production cost and to maximize their profit along with optimal utilization of available resources. 10 different types of products are taken from one of the garments factories of Gazipur, Dhaka to prepare this research work. This model suggests the manufacturer on which products along with how much should be produced to meet the future demand by maintaining the lowest production cost that ultimately maximize the profit of the organization, and also helps Bangladesh to compete in the international market with 'Made in Bangladesh'. LINDO programming is used here to solve this LP model.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.518-519
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• 2006

A connection between pulse-periodical laser radiation power and stability of liquid-metal contacts between powder particles during selective laser sintering (SLS) is determined based on analysis solving the problem of stability of liquid column in the gravity and capillary forces field. On the grounds of obtained relationships the optimization of pulse-periodical laser radiation power and SLS-process duration is realized, that allows to produce voluminous powder porous materials with pre-determined physical and mechanical properties and surface geometry. Results of metallographic investigations of powder porous materials of titanium powder produced with technological regimes calculated by means of obtained relationships are given in the work

• International Journal of Concrete Structures and Materials
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• 제4권1호
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• pp.55-62
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• 2010

The performance evaluation of a sodium lauryl sulfate to qualify as a foaming agent is presented in this paper. When new surfactants are used a systematic study of production parameters on the foam characteristics needs to be undertaken unlike proprietary foaming agents and foam generator for which manufacturer has predefined the parameters. The relative influence of the foam parameters and optimization of factors were carried out through a systematic experiment design. The foam production parameters namely foam generation pressure and dilution ratio of foaming agents are observed to have significant effect on all foam characteristics with the exception of foam output rate on which only foam generation pressure has influence. The foam with good initial foam density need not necessarily be stable foam. The optimum levels of foam production parameters are determined for the surfactant Sodium lauryl sulfate which can be used to produce stable foam for foam concrete production.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVI)
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• pp.207-209
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• 2005

Serum is a potential source of bacterial, mycoplasmal and viral contamination, and it has a possibility of the introduction of serum proteins, prion and pyrogens into the final vaccine product. For porcine Rotavirus vaccine production, it is necessary to develop serum free medium which do not cause those problems. A new serum free medium was developed for porcine Rotavirus vaccine based on DMEM, and the performance of developed serum free medium was evaluated in terms of Vero cell growth and Rotavirus vaccine production. The cell density, gown in serum free medium developed, was similar with that in serum supplemented medium. Also, it was higher than that in other commercially available serum free medium. The productivity of Rotavirus vaccine using serum free medium developed and optimum production strategies will be also discussed.