• 한국해양공학회지
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• 제13권3호통권33호
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• pp.83-91
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• 1999

Taking a view of joining by welding the IN713C to SCM440 and SCM415 steel in production of turbochargers, the frictin welding process may be utilized as a new approach for joining them of other conventional welding processes. It is because the friction welding has more technical and technical and economic advantages than the other welding processes. As this welding process has the characteristics such as curtaliment of production time and materials and cost reduction, etc.. So, this paper deals with determining the preper friction welding condition and analyzing various mechanical properties of friction welded joints of the super heat resisting steel to alloy stee(IN713C to SCM440 and SCM415). And the in-process real-time weld quality evaluation technique by acoustic emission during friction welding of IN713C to SCM440 and SCM415 steels with higher confidence and relibility has been much required even though it might be the first trial approach for developing it. Then, this first study aimed to develop the optimization of dissimilar friction welding of heat resisting steels (INC713 to SCM440, SCM415) for turbine, considering on strength and toughness.

• 한국해양공학회지
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• 제24권1호
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• pp.153-160
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• 2010

This paper deals with the topology optimized design of the riser support structures for floating production storage and offloading units (FPSOs) under global and local loading conditions. For a preliminary study and validation of the numerical approach, a simplified plate under static loading is first evaluated with the representative topology optimization methods, the Homogenization Design Method (HDM) and Density Method (DM) or Simple Isotropic Material with Penalization (SIMP). In the context of the corresponding riser support structures, the design problem is formulated such that structure shapes based on design domain variables are determined by minimizing the compliance subject to a mass target, considering the stress criterion. An initial design model is generated based on an actual FPSO riser support configuration. The topology optimization results present improved design performances under various loading conditions, while staying within the allowable limit of the offshore area.

• 생명과학회지
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• 제9권1호
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• pp.22-28
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• 1999

A bacterium producing exo-inulinase was isolated from soil and identified Pseudomonas sp. and named as Pseudomonas sp. NO5. The optimal culture conditions for the efficient production of exo-inulinase from Pseudomonas sp. NO5 were obtained by cultivating with the medium 1$\%$ sucrose, 0.5$\%$ yeast extract, 0.5$\%$ $(NH_4)_2$$HPO_4$, 0.05$\%$ $MgSO_4$ㆍ$7H_2$0, 0.001$\%$ and $FeSO_4$ㆍ$7H_2$0 at $37^{\circ}C$ in initial pH 7.0 for 20 hours. The enzyme was induced maximally in the presence of sucrose or inulin at early stationary phase about 20 hour after cultivation.

• Journal of Microbiology and Biotechnology
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• 제15권1호
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• pp.197-201
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• 2005

A novel chitinase-producing bacterial strain of Pantoea dispersa was isolated from the sea near Bhavnagar, India for efficient disposal of chitinous waste from the seafood processing industry. The medium components were optimized by using a cubic model in the central composite design for increasing chitinase production. The optimal concentrations for higher production of chitinase were (g l-1) chitin, 10.0; urea, 0.35; MgSO4 7H2O, 0.08, and CaCl2, 0.15. Here, peptone (0.05 g l-1) was used as a constant variant in all trials. Using a statistical optimization method, the chitinase production was found to increase from 108 to 486.4 units ml-1. Chitin was prepared from the crustacean waste, and Fourier Transform Infrared (FTIR) Spectroscopy was used to characterize the isolated chitin. Chitinous waste degradation was studied in terms of chitinase production.

• Journal of Microbiology and Biotechnology
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• 제21권5호
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• pp.470-476
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• 2011

A potent fungus for amylase production, Chrysosporium asperatum, was isolated from among 30 different cultures obtained from wood samples collected in the Junagadh forest, India. All of the isolated cultures were screened for their ability to produce amylase by submerged fermentation. Among the selected cultures, C. asperatum (Class Euascomycetes; Onygenales; Onygenaceae) gave maximum amylase production. In all of the different media tested, potato starch was found to be a good substrate for production of amylase enzyme at $30^{\circ}C$ and pH 5.0. Production of enzyme reached the maximum when a combination of starch and 2% xylose, and organic nitrogen (1% yeast extract) and ammonium sulfate were used as carbon and nitrogen sources, respectively. There was no significant effect of metal ions on enzyme activity. The enzyme was relatively stable at $30^{\circ}C$ for 20 min, and no inhibitory effect of $Ca^{+2}$ ions on amylase production was observed.

• 한국미생물·생명공학회지
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• 제24권4호
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• pp.507-511
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• 1996

Medium optimization for xylitol production from xylose by Candida parapsilosis ATCC 22019 mutant was performed. Effect of various nitrogen sources on xylitol production was investigatied. Of inorganic nitrogenous compounds, ammonium sulfate was effective for xylitol production and yeast extract was the most suitable orangic nitrogen nutrient for enhancement of xylitol production. Effect of inorganic salts such as KH$_{2}$PO$_{4}$ and MgSO$_{4}$-7H$_{2}$0 on xylitol production was also studied. Optimal medium was selected as xylose of 50 g/l, yeast extract of 5 g/l, (NH4$_{4}$)$_{2}$SO$_{4}$ of 5 g/l, KH$_{2}$PO$_{4}$ of 5 g/l, MgSO$_{4}$-7H$_{2}$O of 0.2 g/l. In a fermentor by using the optimal medium, a final xylitol concentration of 37 g/l could be obtained from 50 g/l of xylose with a xylitol yield of 74% and a xylitol productivity of 0.58 g/1-hr. At 300 g/l xylose, fermentation was also carried out and then a final xylitol concentration of 242 g/l was obtained at 272 hours. It was corresponding to xylitol yield of 80.7% and xylitol productivity of 0.58 g/1-hr.

• 전기학회논문지
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• 제57권4호
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• pp.692-699
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• 2008

Semiconductor research and development(R&D) fabs are very different than production fabs in many ways such as the scales of production, job priority, production methods, and performance measures. Efficient operations of R&D fabs are very important to the development of new product, process stability, high yield, and ultimately company competitiveness. This paper proposes the fab-wide scheduling method for operational optimization of the R&D fabs. Most scheduling systems of semiconductor fabs have only focused on maximizing throughput of each separated areas without considering WIP(works in process) flows of entire fab. In this paper, we proposes the a fab-wide scheduling system which schedules all lots to entire fab equipment at once. We develop the MIP(mixed integer programing) model which allocates the lots to production equipment considering many constraints of all processes and the CP(constraint programming) model which determines the sequences of the lots in the production equipment. The proposed FAB-wide scheduling model is applied to the newly constructed R&D fab. As a result, we have accomplished the system based automated job reservation, decrease of the hot lot delay, increase of the queue time satisfaction, the high throughput by maximizing the batch sizes, decrease of the WIP TAT(Turn Around Time).

• 한국항해항만학회지
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• 제39권4호
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• pp.353-360
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• 2015

해양 석유 생산은 '해양'이라는 특성에 기인하는 여러 가지 변수를 동반하면서 막대한 비용과 시간을 필요로 한다. 모든 관련된 프로세스는 인명, 환경 그리고 재산의 손실을 줄이기 위한 치밀한 일련의 계획에 의하여 통제된다. 이 논문은 해양 석유 생산 및 수송의 최적화 문제를 다룬다. 문제 영역의 범위를 정의하기 위해 해양 석유 생산 및 수송 네트워크를 제시하고 그 문제를 해결하기 위한 혼합정수계획모형을 구축하였다. 제안된 최적화 모형의 타당성을 확인하기 위해 가상의 해양 유전과 수요 시장을 바탕으로 MS Office Excel의 해찾기를 이용하여 계산실험들을 수행하였다. 해양 석유 생산 및 수송 네트워크 하위 흐름은 해양 유전에서 생산된 원유를 수요 시장으로 배분하는 해사수송문제가 된다. 이 해사수송문제를 해결하기 위해 집합 패킹 모형을 이용하여 구축된 MoDiSS(Model-based DSS in Ship Scheduling)를 사용하였다. 이러한 연구결과들은 실제적인 해양 석유 생산 및 수송 최적화 문제에 의미 있게 적용될 수 있으리라 사료된다.

• Food Science and Biotechnology
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• 제18권6호
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• pp.1342-1350
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• 2009

This paper investigates the production and optimization of $\beta$-galactosidase enzyme using synthetic medium by Kluyveromyces lactis NRRL Y-8279 in stirred tank bioreactor. Response surface methodology was used to investigate the effects of fermentation parameters on $\beta$-galactosidase enzyme production. Maximum specific enzyme activity of 4,622.7 U/g was obtained at the optimum levels of process variables (aeration rate 2.21 vvm, agitation speed 173.4 rpm, initial sugar concentration 33.8 g/L, incubation time 24.0 hr). The optimum temperature and pH of the $\beta$-galactosidase enzyme produced under optimized conditions were $37^{\circ}C$ and pH 7.0, respectively. The enzyme was stable over a pH range of 6.0-7.5 and a temperature range of $25-37^{\circ}C$. The $K_m$ and $V_{max}$ values for O-nitrophenol-$\beta$-D-galactopyranoside (ONPG) were 1.20 mM and $1,000\;{\mu}mol/min{\cdot}mg$ protein, respectively. The response surface methodology was found to be useful in optimizing and determining the interactions among process variables in $\beta$-galactosidase enzyme production. Hence, this study fulfills the lack of using mathematical and statistical techniques in optimizing the $\beta$-galactosidase enzyme production in stirred tank bioreactor.

• 한국미생물·생명공학회지
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• 제25권3호
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• pp.311-316
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• 1997

A high xylitol producing yeast was isolated from the sludge of xylose manufacturing factory and then identified as Candida tropicalis DS-72 according to physiological properties. The strain was able to produce xylitol in a high concentration up to 72g/l from 100g/l xylose in 32 hours. Medium optimization for xylitol production by C. tropicalis DS-72 was performed. Effect of various nitrogen sources on xylitol production was investigated. Of nitrogenous compounds, yeast extract was the most suitable organic nitrogen nutrient for the enhancement of xylitol production. However, inorganic nitrogen resulted in a low cell concentration and did not produce xylitol. Effect of inorganic salts such as KH$_{2}$PO$_{4}$, and MgSO$_{4}$, 7H$_{2}$O on xylitol production was also studied. Optimal medium was selected as xylose 100g/l, yeast extract 10g/l, KH$_{2}$PO$_{4}$, 5 g/l and MgSO$_{4}$, 7H$_{2}$O 0.2 g/l. Xylitol of 88 g/l was produced from 100 g/l xylose in 30 hours using the optimal medium in a flask. In a fermentor, a fed-batch culture with 300g/l xylose was carried out. A final xylitol concentration of 240 g/l in the culture could be obtained in 43 hours of culture time by maintaining the high level of dissolved oxygen during growth phase and limiting the dissolved oxygen in the same culture during production phase. This result corresponded to a xylitol yield of 80% and a xylitol productivity of 5.58 g/1-h.