• Journal of Technology Innovation
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• v.25 no.3
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• pp.25-50
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• 2017

Declining research competitiveness and inefficiency are constantly being raised in the National Assembly and the media for the Government-funded Research Institutes(GFRIs), which are highly dependent on government funding. These external stakeholders point to the workforce aging of the GFRIs as one of the main causes of inefficiency. They insist that the aging leads to an increase in labor costs, a discontinuity in research, a decrease in employment of new researchers, and a decrease in research competitiveness. However, the GFRIs argue that the aging is a natural phenomenon due to an increase in the age of recruitment, and even if there is an side effect, it is extremely small or even vice versa. It is interesting that there is no empirical study identifying the correlation between the workforce aging and the research performance of the GFRIs, despite the discussion. This study tracked and analyzed the changes of the research performance and the workforce for the five years from 2011 to 2015, and tried to demonstrate the correlation between the workforce aging and the research performance. As a result, we confirmed that there is an inverted U-type correlation between the aging and the papers, one of the research performance, and that the optimal age is 44.96 years. Also, we could not find any correlation between the aging and the patents.

• Journal of Life Science
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• v.18 no.6
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• pp.845-851
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• 2008

${\beta}-Lactamase$, secreted from Bacillus sp. J105 strain was purified to a single band on SDS-PAGE by ammonium sulfate precipitation, ion exchange column chromatography and gel-filtration. The molecular weight of the purified enzyme was 31 kDa on SDS-PAGE and its isoelectric point was 7.35. Optimal pH and temperature for enzymatic reaction were 5 and $40^{\circ}C$, respectively. As a result of total amino acid composition analysis of the purified enzyme, Gly and Ala were occupied 14.1 and 13.3 mole %, respectively. Km and Vmax value of purified enzyme were 1.33 mM and 0.36 mM/ml using ampicillin as a substrate, respectively.

• Archives of Plastic Surgery
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• v.38 no.2
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• pp.161-165
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• 2011

Purpose: Zygomaticomaxillary complex (ZMC) fracture is one of the most common facial injuries after facial trauma. As ZMC composes major facial buttress, it is a key element of the facial contour. So, when we treat these fractures, the operator should have a concern with the symmetry to restore normal appearance and function. But sometimes, unfavorable results may occur. The aim of this study is to analyze the unsatisfied midfacial contour after ZMC fractures reduction retrospectively and to point out the notandum. Methods: 369 patients, treated for fractures of the ZMC were included in the study. After the operation, such as open reduction and internal fixation (ORIF with titanium or absorbable materials), open reduction, and closed reduction, midfacial contour was evaluated with plain films and 3-dimensional computed tomography. And unfavorable asymmetric midfacial contours were correcterd by secondary correction and re-evaluated. Gross photographs were obtained at outpatient clinic. Results: Total of 38 patients had got a facial asymmetry and among of them 24 patients were treated secondary revisional ORIF operations for correction of unfavorable result of after primary reduction. Two of them had received tertiary operations, three patients had got osteotomy more than after one year and six patients had got minor procedures. The etiology of asymmetry were lateral displaced simple fracture of arch (n=2), lateral displaced comminuted fracture of arch (n=6), comminuted arch fracture combined posterior root fracture (n=9), and communited arch and body fracture (n=12), severely contused soft tissue (n=9). After the manipulations outcomes were acceptable. Conclusion: To prevent the asymmetry in ZMC fracture reduction, complete analysis of fracture, choice of appropriate operation technique, consider soft tissue, and secure of zygoma position are important. Especially, we should be more careful about communited fracture of zygomatic body and lateral displacement, root fracture of zygomatic arch. Because they are commom causes that make facial asymmetry. To get optimal result, ensure the definite bony reduction.

• International Journal of Highway Engineering
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• v.11 no.3
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• pp.13-21
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• 2009

The traveler's travel pattern has significantly changed due to the social and economic changes. The travel time among the traveler's pattern is the limited resource. The travelers are trying to maximize the utility of travel with the least travel cost. So, the travelers travel with their own travel time budget in mind, which they can pay or choose to pay for the optimal maximization of the utility of the individuals. This research is to group and extract the specific factors which affect the travel time budget by utilizing the CART analysis method, which enables the analysis of traveler's characteristics and their interrelationship based on the data collected from "2002 Household Travel Practice Research" and then try to derive a model for estimating the traveler’s travel time budget. The result of CART analysis shows that the factors which affect the travel time budget include the traveler's age, size of house, type of house, type of employment, job and relation to the head of household. Considering the affecting factors derived, I developed an estimation model. From that model, we found that the age, size of house and type of house were positively (+) related to the travel time budget while the homeworking people who have less travel frequency as a type of employment were negatively (-) related to it. In particular, from the point of type of job, the housewives, children not yet old enough to attend schools and people who are working in the agricultural, or marine product industries were found to have the negative (-) value while the people who have the administrative, office, management jobs were found to have the positive (+) value.

• Journal of Korean Society of Transportation
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• v.27 no.1
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• pp.143-155
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• 2009

A dynamic traffic assignment (DTA) has recently been implemented in many practical projects. The core of dynamic model is the inclusion of time scale. If excluding the time dimension from a DTA model, the framework of a DTA model is similar to that of static model. Similar to static model, with given exogenous travel demand, a DTA model loads vehicles on the network and finds an optimal solution satisfying a pre-defined route choice rule. In most DTA models, the departure pattern of given travel demand is predefined and assumed as a fixed pattern, although the departure pattern of driver is changeable depending on a network traffic condition. Especially, for morning peak commute where most drivers have their preferred arrival time, the departure time, therefore, should be modeled as an endogenous variable. In this paper, the authors point out some shortcomings of current DTA model and propose an alternative approach which could overcome the shortcomings of current DTA model. The authors substitute a traditional definition for time-dependent OD table by a new definition in which the time-dependent OD table is defined as arrival time-based one. In addition, the authors develop a new DTA model which is capable of finding an equilibrium departure pattern without the use of schedule delay functions. Three types of objective function for a new DTA framework are proposed, and the solution algorithms for the three objective functions are also explained.

• Parasites, Hosts and Diseases
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• v.26 no.4
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• pp.229-238
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• 1988

In vitro culture of Toxoplasma gondii in HL-60 cells and cell-mediates immunity against Toxoplasma in dimethylsulfoxide(DMSO) -induced HL-60 cells, i.e., differentiation into granulocytes, were pursued. HL-60 calls were treated with various concentrations of DMSO, and 1.3%(v/v) for 3 day incubation was chosen as the optimal condition icy differentiation into granulocytes. The degree of differentiation was assayed in physiological and functional aspects in addition to morphological point. When treated with 1.3% DMSO for 3 days, HL-60 cells did not synthesiar DNA materials beyond background level, and showed active chemotactic response to chemotactic peptide, formal-methionyl-leucyl-phenylalanine(FMLP). Morphologically promyelocytes of high nuclearlcytoplasmic(NIC) ratio changed to granulocytes of relatively low WJC ratio. The relationships between HL-60 cells or DMSO-induced HL-60 cells and Toxoplasma were examined after stain with Giemsa and Buorescent dye (acridine orange). HL-60 cells did not show any sign of torso- plasmacidal activity but showed intracellular proliferation of Texoplasma to form rosette for 72 hr co-culture. In contrast, OMSO-induced HL-60 cells phagocytosed Toxoplasma within 1 hr, and performed a process of intracellular digestion of Toxoplasma thereafter. With the above results, it is suggested that phagosome-Iysosome fusion is one of the critical events for the parasitism by Toxoplasma or for susceptibility of host cells. The in vitro culture system of this study has offered a defined condition to study the protozoan parasite-host cell interactions.

• Journal of Wetlands Research
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• v.18 no.3
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• pp.324-329
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• 2016

Constructed wetlands are widely applied in urban and rural areas for various purposes such as pollutants reduction, acquisition of eco-spaces and habitats, flooding reduction, acquisition of water resources and environmental education. Since the design of constructed wetlands utilizes ecosystems, special consideration must be given to ecological mechanisms, environmental mechanisms and hydrological mechanisms. To ensure the sustainable functionality of constructed wetlands, it is necessary to achieve stable flow rate and velocity, and remove sediments to ensure sufficient space for detention. To enhance the efficiency of constructed wetland sedimentation basins, this study determined the optimal position for baffle installation, and applied Computational Fluid Dynamics (CFD) to the cross-sectional design of wetlands. CFD analysis revealed that the decrease in flow velocity with baffle installation enhanced the efficiency of sedimentation of particulate matters. Vertical baffles had higher sedimentation efficiency than those with an inclined angle. When vertical baffles were installed in the sedimentation basin of a hybrid constructed wetland to reduce non-point source pollutants in urban areas, the average flow velocity within the basin decreased by 10~30%, while the sedimentation efficiency improved by 1.3~1.5 times. The application of CFD to constructed wetlands is expected to improve the cost efficiency of designing hybrid constructed wetlands with high removal efficiency.

• Korean Journal of Food Science and Technology
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• v.40 no.5
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• pp.510-515
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• 2008

Microwave energy was applied to the extraction of functional catechins from grape seed. The solvent, absolute ethanol, reached the boiling point when exposed for less than 3 min microwave treatment at 100 W. The effects of independent variables in microwave-assisted extraction (MAE), including microwave power (0-160W, $X_1$), ethanol concentration (0-100%, $X_2$) and extraction time (1-5 min, $X_3$), were investigated on each response variable ($Y_n$), and the contents of catechin and its derivatives were determined via response surface methodology, thereby allowing us to predict their optimal extraction conditions. The predicted maximal values of (+)-catechin, procyanidin $B_2$, (-)-epicatechin, and (-)-epicatechin gallate were 137.99, 72.78, 222.38, and 9.59 mg%, respectively, under different MAE conditions. The predicted extraction conditions for maximum catechin responses were as follows: 104.10 W of microwave power, 45.35% of EtOH, and 4.89 min of extraction time for (+)-catechin (137.99 mg%), 133.16 W, 46.16% and 4.49 min for procyanidin $B_2$ (72.78 mg%), 136.00 W, 41.37% and 4.39 min for (-)-epicatechin (222.38 mg%), 143.20 W, 37.51% and 1.88 min for (-)-epicatechin gallate (9.59 mg%), respectively. The contents of (+)-catechin, procyanidin 1B2 and (-)-epicatechin in MAE were similarly influenced by three independent variables, whereas (-)-epicatechin gallate was influenced less profoundly by ethanol concentration and extraction time.

• Korean Journal of Food Science and Technology
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• v.43 no.3
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• pp.303-314
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• 2011

The purpose of this study was to determine the optimal mixing conditions for two different amounts of added mulberry powder and fresh cream to prepare functional chocolate with added mulberry powder. The experiment was designed according to the central composite response surface design, which showed 10 experimental points, and included two replicates for mulberry powder and fresh cream. The physiochemical, mechanical, and sensory properties of the test were measured, and these values were applied to the mathematical models. The results of the physiochemical and mechanical analyses of each sample, including pH, moisture content, total phenolic content, DPPH free radical scavenging activity, color L, color b, hardness, gumminess, and cohesiveness showed significant differences. The sensory characteristics of the samples tested were significantly different in flavor, texture, sourness, bitterness, and overall acceptability. The optimum formulation calculated by numerical and graphical methods was 25.76 g mulberry powder and 72.21 g fresh cream.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.92-99
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• 2016

A wind turbine is controlled for the purpose of obtaining the maximum power below its rated wind speed. Among the methods of obtaining the maximum power, TSR (Tip Speed Ratio) optimal control and P&O (Perturbation and Observation) control are widely used. The P&O control algorithm using the turbine power and rotational speed is simple, but its slow response is a weak point. Whereas TSR control's response is fast, it requires the precise wind speed. A method of measuring or estimating the wind speed is used to obtain a precise value. However, estimation methods are mostly used, because it is difficult to avoid the blade interference when measuring the wind speed near the blades. Neural networks and various numerical methods have been applied for estimating the wind speed, because it involves an inverse problem. However, estimating the wind speed is still a difficult problem, even with these methods. In this paper, a new method is introduced to estimate the wind speed in the wind-power graph by using the turbine power and rotational speed. Matlab/Simulink is used to confirm that the proposed method can estimate the wind speed properly to obtain the maximum power.