• Title/Summary/Keyword: optical biochip sensors

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Creating Highly Sensitive and Selective Biochip Sensors for the Detection of Organophosphorus/carbamate Pesticides (고감도 및 고선택성의 유기인계/카바메이트계 농약 검출용 바이오칩 센서)

  • Sim, Hyerim;Kim, Suhee;Lee, Jaeyoung;Lee, Hye Jin
    • Applied Chemistry for Engineering
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    • v.20 no.6
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    • pp.571-580
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    • 2009
  • Biochip sensing technologies offering in-situ, fast and real-time measurements in addition to portability can be powerfully utilized in a wide spectrum of research areas including environmental science, food science, medical diagnostics and drug development. In this article, we introduce current research trends and economic aspects of the development of various optical biochip technologies for the analysis of organophosphorus/carbamate pesticides in environmental samples, which is of global importance with serious consequences for both current and future generations. In particular, we will highlight recent efforts made in the creation of highly sensitive and selective optical biochip sensors in conjunction with nanobiotechnologies and microfabrication for the rapid detection of organophosphorus/carbamate pesticides.

Research Trend of Biochip Sensors for Biomarkers Specific to Diagnostics of Lung Cancer Diseases (폐암 질환 진단에 활용 가능한 바이오마커 검출용 바이오칩 센서 연구 동향)

  • Lee, Sang Hyuk;Goh, Eunseo;Lee, Hye Jin
    • Applied Chemistry for Engineering
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    • v.29 no.6
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    • pp.645-651
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    • 2018
  • Lung cancer has the highest death rate of any cancer diseases in Koreans. However, patients often feel difficult to recognize their disease before facing the terminal diagnosis due to the absence of any significant symptoms. Furthermore, the clear detection of an early cancer stage is usually obscure with existing diagnostic methods. For this reason, extensive research efforts have been made on introducing a wide range of biochemical diagnostic tools for the molecular level analysis of biological fluids for lung cancer diagnoses. A chip-based biosensor, one type of the analytical devices, can be a great potential for the diagnosis, which can be used without any further expensive analytical equipments nor skilled analysts. In this mini review, we highlight recent research trends on searching biomarker candidates and bio-chip sensors for lung cancer diagnosis in addition to discussing their future aspects.

MEMS Technology for Biophotonic Applications (바이오포토닉스응용을 위한 MEMS 미세광학소자의 개발)

  • Jeong, Gi-Hun
    • Proceedings of the Optical Society of Korea Conference
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    • 2009.02a
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    • pp.387-388
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    • 2009
  • Biophotonics is an emerging area in a fusion of biology and photonics, especially in advanced bioimaging, optical biosensors, photomodulation, and biochip optical read-out, and optical manipulation. This emerging area also creates many opportunities for interdisciplinary study of biology and photonics. Micro-Electro-Mechanical-System(MEMS) is an attractive technology in miniaturizing sensors and actuactors. For last decade, it has contributed to the development for active and passive small and integrated optical components in optical communication. Recently, this technology is also merging into biology for high sensitive biosensing and high resolution and fast bioimaging in small form factor. In this talk, some key advantages of small optical components and recent biophotonic MEMS achievement will be discussed for miniaturized advanced biophotonic systems.

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