• 해양환경안전학회지
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• 제17권2호
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• pp.105-121
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• 2011

본 연구에서는 시화호의 수질 관리 정책 연구를 위한 최근의 수질 자료 확보를 목적으로 2010년에 시화호 내 외측 해역에서 수질 조사를 수행하였다. 시화호 표층수 수질항목들의 수평적 농도분포는 하천을 통한 담수 유업과 배수갑문을 통한 외해수 유입의 영향으로 인하여 반윌 및 시화 산단 얀근 상류지역에서는 높고 배수갑문으로 갈수록 낮아지는 경향을 나타냈다. 시화호 외해에서는 TN 및 TP가 소래포구에 가까운 곳에서 높은 농도를 나타내었으며, 전체적으로 시화호 내해보다는 상대적으로 낮은 농도를 나타내었다. 시화호 내측의 경우, 여름철 성층 형성 및 저층의 활발한 유기물 분해로 빈산소층이 발달되고 있었다. 수질항목들의 수직적 농도분포의 경우, 용존영양염, TN 및 TP는 표층보다 저층에서 높았지만, COD, 클로로필-a 및 POC는 이와 반대로 저층보다 표층에서 높은 분포를 나타냈다. 시화호 표층수에서 염분은 용존영양염과 양호한 음의 상관성을 보여 담수 기원의 영양염 공급이 확인되었고, 이에 의한 식물플랑크톤의 대증식으로 COD 및 POC가 높게 나타났다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권4호
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• pp.346-355
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• 2020

Purpose: Peroxisome proliferator-activated receptor gamma (PPAR-γ) has a key role in hepatic fibrogenesis by virtue of its effect on the hepatic stellate cells (HSCs). Although many studies have shown that PPAR-γ agonists inhibit liver fibrosis, the mechanism remains largely unclear, especially regarding the cross-talk between PPAR-γ and other potent fibrogenic factors. Methods: This experimental study involved 25 male Wistar rats. Twenty rats were subjected to bile duct ligation (BDL) to induce liver fibrosis, further divided into an untreated group (BDL; n=10) and a group treated with the PPAR-γ agonist thiazolidinedione (TZD), at 14 days post-operation (BDL+TZD; n=10). The remaining 5 rats had a sham operation (sham; n=5). The effect of PPAR-γ agonist on liver fibrosis was evaluated by histopathology, protein immunohistochemistry, and mRNA expression quantitative polymerase chain reaction. Results: Histology and immunostaining showed markedly reduced collagen deposition, bile duct proliferation, and HSCs in the BDL+TZD group compared to those in the BDL group (p<0.001). Similarly, significantly lower mRNA expression of collagen α-1(I), matrix metalloproteinase-2, platelet-derived growth factor (PDGF)-B chain, and connective tissue growth factor (CTGF) were evident in the BDL+TZD group compared to those in the BDL group (p=0.0002, p<0.035, p<0.0001, and p=0.0123 respectively). Moreover, expression of the transforming growth factor beta1 (TGF-β1) was also downregulated in the BDL+TZD group (p=0.0087). Conclusion: The PPAR-γ agonist inhibits HSC activation in vivo and attenuates liver fibrosis through several fibrogenic pathways. Potent fibrogenic factors such as PDGF, CTGF, and TGF-β1 were downregulated by the PPAR-γ agonist. Targeting PPAR-γ activity may be a potential strategy to control liver fibrosis.

• 대한두개안면성형외과학회지
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• 제12권2호
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• pp.116-120
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• 2011

Purpose: Scalp avulsion is a life-threatening injury that may cause trauma to the forehead, eyebrows, and periauricular tissue. It is difficult to treat scalp avulsion as it may lead to severe bleeding. Therefore, emergency scalp replantation surgery is necessary, and we must consider the function, aesthetics, and psychology of the patients. A case of scalp avulsion leading to massive bleeding was encountered by these authors, which led to a failure to achieve the proper operation conditions in an adequate time period. Methods: A 49-year-old female was hospitalized due to having had her head caught in a rotatory machine, causing complete scalp avulsion which included the dorsum of the nose, both eyebrows, and ears. Emergent microsurgical replantation was performed, where a superficial temporal artery and a vein were anastomosed, but the patient's vital signs were too unstable for further operation due to excessive blood loss. Three days after the microanastomosis, venous congestion developed at the replanted scalp, and a medicinal leech was used. Leech therapy resolved the venous congestion. A demarcation then developed between the vitalized scalp tissue and the necrotized area. Debridement was performed 2 times on the necrotized scalp area. Finally, split-thickness skin graft with a dermal acellular matrix ($Matriderm^{(R)}$) was performed on the defective areas, which included the left temporal area, the occipital area, and both eyebrows. Results: The forehead, vertex, right temporal area, and half of the occipital area were successfully replanted, and the hair at the replanted scalp was preserved. As stated above, two-thirds of the scalp survived; the patient could cover the skin graft area with her hair, and could wear a wig. Conclusion: Complete scalp avulsion needs emergent replantation with microsurgical revascularization, but it often leads to serious vital conditions. We report a case with acceptable results, although the microanastomosed vessel was minimal due to the patient's unstable vital signs.

• 정보처리학회 논문지
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• 제13권9호
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• pp.444-452
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• 2024

본 연구는 Layer Importance Evaluation을 통해 도출된 화재 감지에 최적화된 딥러닝 아키텍처를 제안한다. 기존의 합성곱 신경망(Convolutional Neural Network, CNN) 기반 화재 감지 시스템의 불필요한 복잡성과 연산을 초래하는 문제점을 해결하기 위해, Layer Importance Evaluation 기법을 통해 가중치 및 활성화 값에 근거한 모델의 내부 레이어의 동작을 분석하고, 화재 감지에 기여도가 높은 레이어를 식별한 뒤, 식별한 레이어만으로 모델을 재구성하여, 기존 모델과의 성능 지표를 비교 분석하였다. Xception, VGG19, ResNet, EfficientNetB5 등 네 가지 전이 학습 모델을 사용하여 화재 데이터를 학습시킨 후, Layer Importance Evaluation기법을 적용하여 각 레이어의 가중치와 활성화 값을 분석한 뒤 기여도가 가장 높은 상위 랭크 레이어들을 선별하여 새로운 모델을 구축하였다. 연구 결과, 구현된 아키텍처는 기존 모델 대비 약 80% 가량 경량화 된 파라미터로도 동등한 성능을 유지하며, 약 3~5배가량 신속한 학습 속도를 가지면서도 기존의 복잡한 전이학습 모델에 비해 정확도, 손실, 혼동행렬 지표에서 동등한 성능을 출력함으로써, 화재 감시 장비의 효율성을 높이는 데 기여할 수 있음을 확인하였다.

• 한국융합학회논문지
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• 제13권1호
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• pp.71-80
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• 2022

이 연구의 목적은 빅데이터 분석 방법을 이용하여 발명 교육 센터에 대한 사회적 인식을 확인해 보는 데 있다. 이를 위해 TEXTOM 사이트를 이용하여 네이버와 다음 사이트의 블로그, 카페, 뉴스 채널에서 '발명+교육+센터'를 검색 키워드로 2014년 1월부터 2021년 9월까지의 데이터를 수집하였다. 수집된 데이터는 TEXTOM 사이트에서 정제하였으며, 텍스트 마이닝 분석과 의미 연결망 분석을 위해 TEXTOM 사이트, Ucinet 6, Netdraw 프로그램을 이용하였다. 수집된 데이터는 1차와 2차의 정제 과정을 거쳐 단어빈도를 바탕으로 주요 키워드 60개를 선정하였으며, 선정된 주요 키워드는 매트릭스 데이터로 변환하여 의미 연결망 분석을 실시하였다. 이 연구의 텍스트 마이닝 분석 결과 '학생', '운영', '한국발명진흥회', '특허청' 등이 의미 있는 키워드임을 확인하였다. 의미 연결망 분석 결과 발명 교육 센터와 관련된 '교육 운영', '발명 대회', '교육 과정 및 진행', '사업 모집 및 지원', '주관 및 선정 기관' 등 5개의 군집을 확인할 수 있었다. 이 연구의 결과는 발명 교육 센터에 대한 연구를 수행하는 연구자나 정책 입안자의 학술 연구에 활용될 수 있을 것이다.

• 대한치과보철학회지
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• 제38권5호
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• pp.575-582
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• 2000

This investigation was designed to determine whether heat-pressing and/or simulated heat treatments affected the flexure strength and the microstructure of the lithium disilicate glass-ceramic in the IPS Empress 2 system. Four groups of the specimens were prepared as follows: group 1 - as-received material, group 2 - heat-pressed material; group 3 - heat-pressed and simulated initial heat-treated material; group 4 - heat-pressed and the simulated heat-treated material with full firings for a final restoration. The three-point bending test and the scanning elec-tron microscope (SEM) analysis was conducted for the purpose of this study. The flexure strength of group 2 was significantly higher than that of group 1. However, there were no significant differences in strength among group 2, 3, and 4, and between group 1 and 4. The SEM micrographs of the lithium disilicate glass-ceramic showed the closely packed, multi-directionally interlocking microstructure of numerous lithium disilicate crystals protruding from the glass matrix. The crystals of the heat-pressed materials (group 2, 3, and 4) were a little denser and about two times bigger than those of the as-received material (group 1). This change of microstructure is more obviously exhibited particularly between group 1 and 2. However, there was no a marked difference among group 2, 3, and 4 after the heat-pressing procedure. Although there were significant increase of the strength and some changes of the microstructure after the heat-pressing operation, the combination of the heat-pressing and the simulated subsequent heat treatments did not produce the increase of strength of IPS Empress 2 glass-ceramic.

• Journal of Periodontal and Implant Science
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• 제29권2호
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• pp.355-373
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• 1999

Many researches have been reported that collagen as cellular stroma, matrix of grafting materials, mediator of agents for the purpose of promoting healing process invivo, but the responses in vivo were seen various. The goal of this experiment is to assess the effect of collagen on bony healing, through histological evaluation of implanted collagen on the calvarial defect in rats. 2-month-old Sprague-Dawley, 24 rats were used and 12 rats assigned to each group of control and test. Defect of 5mm in diameter was made on the calvarial bone with trephine bur. Following thorough saline rinse, defect of control group was left in empty and that of experimental group was filled with fibrillar collagen($COLLATAPE^{(R)}$, COLLA-TEC. INC. U.S.A.) soaked in saline. 3 rats in each group were sacrificed at 3, 7, 14, 21 days after operation respectively, and the tissue blocks were prepared for light microscope with H-E for evaluation of overall healing, with TRAP(tartrate resistant acid phosphatase) for evaluation of osteoclastic activity and with immunohistochemical staining for macrophages. The results were as follows : 1. In the control group, inflammatory responses were disappeared at day 14, but, in the experimental group inflammatory infiltrates were reduced at day 21. Thus, the experimental group showed more severe soft tissue inflammation than control group. 2. Both control and experimental group showed slight appositional growth at day 7 and gradual bony growth to 21th day. But, complete bony healing of the defect was not shown. There was no significant difference in bony healing between control and experimental group 3. Specific response of macrophages for implanted collagen was observed at day 14 in the experimental group. In conclusion, although fibrillar collagen caused inflammation of soft tissue during initial healing period, inflammatory responses by fibrillar collagen didn't inhibit bony regeneration and implanted collagen was biodegradaded by macrophages. Thus, we expect that fibrillar collagen can be used for useful mediator of graft materials or growth factors.

• Archives of Plastic Surgery
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• 제37권3호
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• pp.250-255
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• 2010

Purpose: Pincer nail is a relatively rare deformity characterized by an increase in transverse curvature along the longitudinal axis of the nail. This curvature commonly increases from proximal to distal end of nail, leading to pinching, curling, and distortion of the underlying soft tissue and resulting frequently in severe pain. Numerous surgical procedures have been reported. Preserving the width of the nail in the correction of the pincer nail is very important for functional and aesthetic reasons. We report the results of the correction of the pincer nail using autogenous dermofat graft with a good result. Methods: From May 2006 to September 2008, dermofat graft was performed in 6 patients with pincer nail. Patients were four women and two men, and the average age was 51. The affected digits were the unilateral great toes in four patients and the unilateral thumbs in two patients. Average follow-up period was 13 months. Surgical procedure was removal of nail using an elevator to avoid damage to the nail bed. An incision was created in distal portion of hyponychium. Paronychium was dissected from distal phalanx by periosteal elevator through incision of hyponychium and tunnel was made. Then dermofat grafts harvested from inguinal area were inserted into the tunnel. Finally, a silicone sheet was inserted eponychial fold for prevention of synechia. Objective assessment was evaluated by use of the width index and height index. Results: All patients reported resolution of the pain and soft tissue pinching sensation that they had before the operation. There was good adherence between the nail plate and the underlying nail bed. The nails have regrown and were corrected in a normal and flattened appearance. The width index and height index were improved. Conclusion: The autogenous dermofat graft seems to provide an effective treatment of the pincer nail with preservation of the nail matrix.

• Geomechanics and Engineering
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• 제23권1호
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• pp.51-59
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• 2020

In this paper, the WEKA platform was used to mine and analyze measured data of floor failure depth and a prediction system of floor failure depth was developed with Java. Based on the standardization and discretization of 35-set measured data of floor failure depth in China, the grey correlation degree analysis on five factors affecting the floor failure depth was carried out. The correlation order from big to small is: mining depth, working face length, floor failure resistance, mining thickness, dip angle of coal seams. Naive Bayes model, neural network model and decision tree model were used for learning and training, and the accuracy of the confusion matrix, detailed accuracy and node error rate were analyzed. Finally, artificial neural network was concluded to be the optimal model. Based on Java language, a prediction system of floor failure depth was developed. With the easy operation in the system, the prediction from measured data and error analyses were performed for nine sets of data. The results show that the WEKA prediction formula has the smallest relative error and the best prediction effect. Besides, the applicability of WEKA prediction formula was analyzed. The results show that WEKA prediction has a better applicability under the coal seam mining depth of 110 m~550 m, dip angle of coal seams of 0°~15° and working face length of 30 m~135 m.

• Journal of Power Electronics
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• 제19권1호
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• pp.190-200
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• 2019

The flyback converter, which can be regarded as a nonlinear time-varying system, has complex dynamics and nonlinear behaviors. These phenomena can affect the stability of the converter. To simplify the modeling process and retain the information of the output capacitor branch, a special sampled-data model of a peak current-mode (PCM) controlled flyback converter is established in this paper. Based on this, its dynamic behaviors are analyzed, which provides guidance for designing the circuit parameters of the converter. With the critical stability boundary equation derived by a Jacobian matrix, the stable operation range with a varied output capacitor, proportional coefficient of error the amplifier, input voltage, reference voltage and slope of the compensation ramp of a PCM controlled flyback converter are investigated in detail. Research results show that the duty ratio should be less than 0.5 for a PCM controlled flyback converter without ramp compensation to operate in a stable state. The stability regions in the parameter space between the output capacitor and the proportional coefficient of the error amplifier are enlarged by increasing the input voltage or by decreasing the reference voltage. Furthermore, the ramp compensation also can extend to the stable region. Finally, time-domain simulations and experimental results are presented to verify the theoretical analysis results.