• Title/Summary/Keyword: operating characteristic

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Serum anti-M$\ddot{u}$llerian hormone levels as a predictor of the ovarian response and IVF outcomes

  • Choi, Min-Hye;Yoo, Ji-Hee;Kim, Hye-Ok;Cha, Sun-Hwa;Park, Chan-Woo;Yang, Kwang-Moon;Song, In-Ok;Koong, Mi-Kyoung;Kang, Inn-Soo
    • Clinical and Experimental Reproductive Medicine
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    • v.38 no.3
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    • pp.153-158
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    • 2011
  • Objective: The aim of this study was to investigate whether anti-M$\ddot{u}$llerian hormone (AMH) levels could be predict ovarian poor/hyper response and IVF cycle outcome. Methods: Between May 2010 and January 2011, serum AMH levels were evaluated with retrospective analysis. Three hundred seventy infertile women undergoing 461 IVF cycles between the ages of 20 and 42 were studied. We defined the poor response as the number of oocytes retrieved was equal or less than 3, and the hyper response as more than 25 oocytes retrieved. Serum AMH was measured by commercial enzymelinked immunoassay. Results: The number of oocytes retrieved was more correlated with the serum AMH level (r=0.781, $p$ <0.01) than serum FSH (r=-0.412, $p$ <0.01). The cut-off value of serum AMH levels for poor response was 1.05 ng/mL (receiver operating characteristic [ROC] curves/area under the curve [AUC], $ROC_{AUC}$=0.85, sensitivity 74%, specificity 87%). Hyper response cut-off value was 3.55 ng/mL $ROC_{AUC}$=0.91, sensitivity 94%, specificity 81%). When the study group was divided according to the serum AMH levels (low: <1.05 ng/mL, middle: 1.05 ng/mL - 3.55 ng/mL, high: >3.55 ng/mL), the groups showed no statistical differences in mature oocyte rates (71.6% vs. 76.5% vs. 74.8%) or fertilization rates (76.9% vs. 76.6% vs. 73.8%), but showed significant differences in clinical pregnancy rates (21.7% vs. 24.1% vs. 40.8%, $p$=0.017). Conclusion: The serum AMH level can be used to predict the number of oocytes retrieved in patients, distinguishing poor and high responders.

THE CHANGES OF SERUM C-REACTIVE PROTEIN IN THE HEAD AND NECK INFECTION (두경부 감염 환자에서 혈청 내 C-Reactive Protein의 변화)

  • Lee, Ju-Hyun;Kim, Chin-Soo;Lee, Sang-Han;Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.29 no.1
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    • pp.5-13
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    • 2003
  • The purpose of this study is to determine the value of serum concentration of C-reactive protein(CRP) in comparison with ESR and leukocyte as the tools for diagnosis and follow-up study of infection. For this study, thirty-one patients with head and neck infection and thirty-two patients performed the orthognathic surgery were selected for experimental and control groups each other. we analyzed the blood sample daily to measure CRP, ESR and leukocytosis. The results of this study are as the following : 1. Serum C-Reactive Protein levels in the experimental group were higher than control group and the pattern of CRP changes continued to decline in both groups(P<0.001). 2. ESR changes in both groups were scattered without any special pattern. 3. Correlation between CRP and Leukocyte was higher than others(r=0.664, P<0.01). 4. In the Receiver Operating Characteristic(ROC) Curve of experimental group, rapid increase of CRP curve and Area under the curve(AUC) value, 0.774, indicate the high accuracy of estimation. 5. In experimental group, sensitivity of CRP, ESR, and Leukocytosis on recovery day were 83%, 17% and 71%. Based on the results of this study, we could conclude that determination of CRP is more useful method to diagnosis and follow-up study of infection than other commonly used variables in oral and maxillofacial region.

A New Shock Index for Predicting Survival of Rats with Hemorrhagic Shock Using Perfusion and Lactate Concentration Ratio (흰쥐의 출혈성 쇼크에서 관류와 젖산 농도 비를 이용한 새로운 생존 예측 지표 개발)

  • Choi, Jae-Lim;Nam, Ki-Chang;Kwon, Min-Kyung;Jang, Kyung-Hwan;Kim, Deok-Won
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.4
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    • pp.1-9
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    • 2011
  • Hemorrhagic shock is a clinically widespread syndrome characterized by inadequate oxygenation and supply. It is important to diagnose hemorrhagic shock in its early stage for improving treatment effects and survival rate. However, an accurate diagnosis and treatment could be delayed in the early stage of hemorrhagic shock by evaluating only vital signs such as heart rate and blood pressure. There have been many studies for the early diagnosis of hemorrhagic shock, reporting that lactate concentration and perfusion were useful variables for tissue hypoxia and metabolic acidosis. In this study, we measured both perfusion using a laser Doppler flowmeter and lactate concentration from the volume controlled hemorrhagic shock using rats. We also proposed a new shock index which was calculated by dividing lactate concentration by perfusion for early diagnosis. As a result of the survival prediction by the proposed index with the receiver operating characteristic curve method, the sensitivity, specificity, and accuracy of survival were 90.0, 96.7 and 94.0%, respectively. The proposed index showed the fastest significant difference among the other parameters such as blood pressure and heart rate. It could offer early diagnosis and effective treatment for human hemorrhagic shock if it is applicable to humans.

A Study on Relationship Between Violation of Environmental Regulations and Firm's Characteristics (기업특성과 환경규제 위반의 관계 연구)

  • Kim, In-Su
    • Management & Information Systems Review
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    • v.31 no.4
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    • pp.33-56
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    • 2012
  • The purposes of this paper are analysed the relationship between environmental regulation and financial performance in Korea. The financial performance of listed companies and Outside Auditing firms was evaluated by logistic regression. First, R&D investment is proportionally correlated with the ability to comply with environmental regulations. It can be explained increase of investment in R&D causes enhancement of compliance of environmental regulations with development of environmental technology. Second, statistical significance is not observed between financial aspects such as current ratio, debt-to-equity ratio, cash flow, and operating profit margin and the ability to comply with environmental regulations. It indicates high financial performance could not directly lead investment for the ability of that. Third, in terms of structural aspects, firm size and employees have a reliable correlation with compliance with environmental regulations due to high attention of larger firms for PR, and IR, while capital intensity and gravity, and exports do not. Finally, violation of environmental regulations is not affect by the controlling shareholder ownership.

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Predictive value of sperm motility characteristics assessed by computer-assisted sperm analysis in intrauterine insemination with superovulation in couples with unexplained infertility

  • Youn, Joung-Sub;Cha, Sun-Hwa;Park, Chan-Woo;Yang, Kwang-Moon;Kim, Jin-Yeong;Koong, Mi-Kyoung;Kang, Inn-Soo;Song, In-Ok;Han, Sang-Chul
    • Clinical and Experimental Reproductive Medicine
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    • v.38 no.1
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    • pp.47-52
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    • 2011
  • Objective: To determine whether characteristics of sperm motility obtained by computer-assisted sperm analysis (CASA) could predict pregnancy after intrauterine insemination (IUI) in couples with unexplained infertility. Methods: Three hundred eighty-three cycles of intrauterine insemination with superovulation were retrospectively analyzed. Semen analysis was performed with CASA before and after swim-up and the parameters were compared between pregnant and non-pregnant women. Results: The pregnancy rate per cycle was 14.1%. Pregnant and non-pregnant women were comparable in terms of age, infertility duration, the number of dominant follicles. While sperm concentration, motility, and parameters such as average path velocity (VAP) and percentage rapid (RAPID) before semen preparation were significantly different between the pregnancy and non-pregnancy groups, there were no differences in sperm parameters when comparing the two groups after preparation. Using a receiver operating characteristic curve to measure sensitivity and specificity, the optimal threshold value for the predictors of pregnancy was revealed to be a concentration of ${\geq}111{\times}10^6/mL$, a motility of ${\geq}$ 51.4%, and RAPID ${\geq}$ 30.1% before preparation for IUI. Conclusion: Sperm parameters including concentration, motility, and RAPID before sperm preparation could have predictive value for pregnancy outcome after intrauterine insemination with superovulation in couples with unexplained infertility, and would be helpful when counseling patients before they make the decision to proceed with IVF/ICSI-ET.

Risk factors affecting the difficulty of fiberoptic nasotracheal intubation

  • Rhee, Seung-Hyun;Yun, Hye Joo;Kim, Jieun;Karm, Myong-Hwan;Ryoo, Seung-Hwa;Kim, Hyun Jeong;Seo, Kwang-Suk
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.20 no.5
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    • pp.293-301
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    • 2020
  • Background: The success rate of intubation under direct laryngoscopy is greatly influenced by laryngoscopic grade using the Cormack-Lehane classification. However, it is not known whether grade under direct laryngoscopy can also affects the success rate of nasotracheal intubation using a fiberoptic bronchoscpe, so this study investigated the same. In addition, we investigated other factors that influence the success rate of fiberoptic nasotracheal intubation (FNI). Methods: FNI was performed by 18 anesthesiology residents under general anesthesia in patients over 15 years of age who underwent elective oral and maxillofacial operations. In all patients, the Mallampati grade was measured. Laryngeal view grade under direct laryngoscopy, and the degree of secretion and bleeding in the oral cavity was measured and divided into 3 grades. The time required for successful FNI was measured. If the intubation time was > 5 minutes, it was evaluated as a failure and the airway was managed by another method. The failure rate was evaluated using appropriate statistical method. Receiver operating characteristic (ROC) curves and area under the curve (AUC) were also measured. Results: A total of 650 patients were included in the study, and the failure rate of FNI was 4.5%. The patient's sex, age, height, weight, Mallampati, and laryngoscopic view grade did not affect the success rate of FNI (P > 0.05). BMI, the number of FNI performed by residents (P = 0.03), secretion (P < 0.001), and bleeding (P < 0.001) grades influenced the success rate. The AUCs of bleeding and secretion were 0.864 and 0.798, respectively, but the AUC of BMI, the number of FNI performed by residents, Mallampati, and laryngoscopic view grade were 0.527, 0.616, 0.614, and 0.544, respectively. Conclusion: Unlike in intubation under direct laryngoscopy, in the case of FNI, oral secretion and nasal bleeding had a significant effect on FNI difficulty than Mallampati grade or Laryngeal view grade.

A Study on the Characteristic of Conversion Efficiency for Three-way Catalyst in Hydrogen-Natural Gas Blend Fueled Engine (수소-천연가스 혼합연료 엔진의 삼원촉매 전환효율 특성 연구)

  • Park, Cheol-Woong;Yi, Ui-Hyung;Kim, Chang-Gi;Lee, Janghee
    • Journal of the Korean Institute of Gas
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    • v.20 no.6
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    • pp.23-30
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    • 2016
  • The conventional natural gas engine realized lean combustion for the improved efficiency. However, in order to cope with exhaust gas regulations enforced gradually, the interest has shifted at the stoichiometric mixture combustion system. The stoichiometric mixture combustion method has the advantage of a three-way catalyst utilization whose purification efficiency is high, but the problem of thermal durability and the fuel economy remains as a challenge. Hydrogen-natural gas blend fuel (HCNG) can increase the rate of exhaust gas recirculation (EGR) because the hydrogen increases burning speed and lean flammability limit. The increase in the EGR rate can have a positive impact on heat resistance of the engine due to the decreased combustion temperature, and further can increase the compression ratio for efficient combustion. In this study, to minimize the exhaust emission developed HCNG engine with stoichiometric combustion method, developed three-way catalyst was applied to evaluate the conversion characteristics. The tests were carried out during the steady state and transient operating conditions, and the results were compared for both the conventional and proto-three-way catalyst of HCNG engine for city buses.

Prediction of Shift in Fish Distributions in the Geum River Watershed under Climate Change (기후변화에 따른 금강 유역의 어류 종분포 변화 예측)

  • Bae, Eunhye;Jung, Jinho
    • Ecology and Resilient Infrastructure
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    • v.2 no.3
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    • pp.198-205
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    • 2015
  • Impacts of climate change on aquatic ecosystems range from changes in physiological processes of aquatic organisms to species distribution. In this study, MaxEnt that has high prediction power without nonoccurrence data was used to simulate fish distribution changes in the Geum river watershed according to climate change. The fish distribution in 2050 and 2100 was predicted with RCP 8.5 climate change scenario using fish occurrence data (a total of 47 species, including 17 endemic species) from 2007 to 2009 at 134 survey points and 9 environmental variables (monthly lowest, highest and average air temperature, monthly precipitation, monthly lowest, highest and average water temperature, altitude and slope). The fitness of MaxEnt modeling was successful with the area under the relative operating characteristic curve (AUC) of 0.798, and environmental variables that showed a high level of prediction were as follows: altitude, monthly average precipitation and monthly lowest water temperature. As climate change proceeds until 2100, the probability of occurrence for Odontobutis interrupta and Acheilognathus yamatsuatea (endemic species) decreases whereas the probability of occurrence for Microphysogobio yaluensis and Lepomis macrochirus (exotic species) increases. In particular, five fish species (Gnathopogon strigatus, Misgurnus mizolepis, Erythroculter erythropterus, A. yamatsuatea and A. koreensis) were expected to become extinct in the Geum river watershed in 2100. In addition, the species rich area was expected to move to the northern part of the Geum river watershed. These findings suggest that water temperature increase caused by climate change may disturb the aquatic ecosystem of Geum river watershed significantly.

A Ranking Cleaning Policy for Embedded Flash File Systems (임베디드 플래시 파일시스템을 위한 순위별 지움 정책)

  • Kim, Jeong-Ki;Park, Sung-Min;Kim, Chae-Kyu
    • The KIPS Transactions:PartA
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    • v.9A no.4
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    • pp.399-404
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    • 2002
  • Along the evolution of information and communication technologies, manufacturing embedded systems such as PDA (personal digital assistant), HPC (hand -held PC), settop box. and information appliance became realistic. And RTOS (real-time operating system) and filesystem have been played essential re]os within the embedded systems as well. For the filesystem of embedded systems, flash memory has been used extensively instead of traditional hard disk drives because of embedded system's requirements like portability, fast access time, and low power consumption. Other than these requirements, nonvolatile storage characteristic of flash memory is another reason for wide adoption in industry. However, there are some technical challenges to cope with to use the flash memory as an indispensable component of the embedded systems. These would be relatively slow cleaning time and the limited number of times to write-and-clean. In this paper, a new cleaning policy is proposed to overcome the problems mentioned above and relevant performance comparison results will be provided. Ranking cleaning policy(RCP) decides when and where to clean within the flash memory considering the cost of cleaning and the number of times of cleaning. This method will maximize not only the lifetime of flash memory but also the performance of access time and manageability. As a result of performance comparison, RCP has showed about 10 ~ 50% of performance evolution compared to traditional policies, Greedy and Cost-benefit methods, by write throughputs.

N-Terminal Pro-B-type Natriuretic Peptide Is Useful to Predict Cardiac Complications Following Lung Resection Surgery

  • Lee, Chang-Young;Bae, Mi-Kyung;Lee, Jin-Gu;Kim, Kwan-Wook;Park, In-Kyu;Chung, Kyung-Young
    • Journal of Chest Surgery
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    • v.44 no.1
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    • pp.44-50
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    • 2011
  • Background: Cardiovascular complications are major causes of morbidity and mortality following non-cardiac thoracic operations. Recent studies have demonstrated that elevation of N-Terminal Pro-B-type natriuretic peptide (NT-proBNP) levels can predict cardiac complications following non-cardiac major surgery as well as cardiac surgery. However, there is little information on the correlation between lung resection surgery and NT-proBNP levels. We evaluated the role of NT-proBNP as a potential marker for the risk stratification of cardiac complications following lung resection surgery. Material and Methods: Prospectively collected data of 98 patients, who underwent elective lung resection from August 2007 to February 2008, were analyzed. Postoperative adverse cardiac events were categorized as myocardial injury, ECG evidence of ischemia or arrhythmia, heart failure, or cardiac death. Results: Postoperative cardiac complications were documented in 9 patients (9/98, 9.2%): Atrial fibrillation in 3, ECG-evidenced ischemia in 2 and heart failure in 4. Preoperative median NT-proBNP levels was significantly higher in patients who developed postoperative cardiac complications than in the rest (200.2 ng/L versus 45.0 ng/L, p=0.009). NT-proBNP levels predicted adverse cardiac events with an area under the receiver operating characteristic curve of 0.76 [95% confidence interval (CI) 0.545~0.988, p=0.01]. A preoperative NT-proBNP value of 160 ng/L was found to be the best cut-off value for detecting postoperative cardiac complication with a positive predictive value of 0.857 and a negative predictive value of 0.978. Other factors related to cardiac complications by univariate analysis were a higher American Society of Anesthesiologists grade, a higher NYHA functional class and a history of hypertension. In multivariate analysis, however, high preoperative NT-proBNP level (>160 ng/L) only remained significant. Conclusion: An elevated preoperative NT-proBNP level is identified as an independent predictor of cardiac complications following lung resection surgery.