• 대한물리치료과학회지
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• 제25권1호
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• pp.52-61
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• 2018

Background: The purpose of this study was to investigate the effect of open and close kinetic chain exercise on the muscle activity of pectoralis major and triceps. Method: Twenty healthy male college students were assessed three times over two weeks. The participants were randomly assigned to OKCE(Open Kinetic Chain Exercise) and CKCE(Close Kinetic Chain Exercise). On the first day, the 7th day and the last day, The MP(mean power) and PT(peak torque) of the PM(pectoralis major) and TR(triceps) during the exercise were measured with an electromyography device and the study was compared. Result: In the present study, it was found that Statistical analysis of the measured values at the end of experimental period revealed statistically significant differences in the MP and PT values of TR and PM. Conclusion: These findings suggest that CKCE and OKCE may be an effective physical therapy intervention for strengthening muscular activity in patients with low activity in the upper limb, including normal subjects, although it is not suitable for effective exercise by selecting either CKCE or OKCE.

• 대한수학교육학회지:학교수학
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• 제9권1호
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• pp.141-160
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• 2007

본 연구의 목적은 대수 문장제를 해결하기 위하여 학생들이 이전지식이나 경험을 어떻게 적용하는가를 조사하고자 학생들의 풀이과정에 대한 유사성을 일련의 표시(chain of signification) 관점에서 분석하는 것이다. 이를 위하여 본 연구에서는 중학생 3명을 대상으로 사례 연구를 실시하였다. 연구 결과, 학생A나 학생C는 (반)열린 공식을 해법 원리로 생각하여 구체화하는 과정을 일련의 표시로 구성하였다. 학생A와 학생C는 문제를 읽으면서 숫자 정보와 텍스트를 기반으로 정신적 모델을 구성하였으며, 그 의미(기의)와 기록(기표) 과정을 점진적으로 구성함으로써 일련의 표시 과정을 구성하였다. 학생A의 표시과정은 숫자나 문자, 그리고 그리기가 혼합된 것이었다. 그러나 학생C와 학생B는 단지 숫자나 문자만으로 구성하였다. 특히, 학생B는 특정한 문제정보만을 근거로 그 상황을 생각하지 않고, 자신의 알고리즘을 적용하기 위하여 자신이 구성한 규칙을 적용하고자 하는 시행착오에 대한 유사성을 구성하였다.

• Archives of Pharmacal Research
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• 제20권5호
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• pp.501-506
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• 1997

Novel 9-[2-fluoro-4-hydroxy-3-hydroxymethyl-2-butenyl]adenine and its related compounds were designed and synthesized as open-chain analogues of neplanocin A. Alkylation of adenine or pyrimidine bases with the mesylate 4 was chosen as a simple approach to the synthesis of 2-fluoro-2-butenylated nucleosides. Mesylate 4 was prepared from dihydroxyacetone dimer via four steps in 58% overall yield. The synthesized compounds were evaluated their antiviral activity against HSV, HIV and Polio viruses.

• 대한물리의학회지
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• 제9권4호
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• pp.475-483
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• 2014

PURPOSE: The purpose of the study was to determine the effects of close kinetic chain resistant exercise of lower extremity on the gait with stroke patients. METHODS: The subjects were 50 patients who were diagnosed with cerebrovascular accident. They were randomly assigned either to a close kinetic chain resistant exercise of lower extremity group (study group)(n=25) or open kinetic chain resistant exercise of lower extremity exercise group (control group)(n=25). Gait abilities were measured by using Timed Up & Go (TUG) test, Functional Gait Assessment (FGA) and spatio-temporal gait variable that were velocity, cadence, stride length, double limb support by 3 axises wireless accelerometer and sway angle of center of mass by same instrument. RESULTS: Study group and control group before and after the intervention there were significantly difference in TUG, FGA, spatio-temporal gait variables and sway angle of center of mass (p<.05). There were significantly different between study group and control group for all variables at post-exercise. CONCLUSION: When all is said and done it is expected to be used as a method for the treatment and prevention in the process of rehabilitation of patients with stroke. In its final analysis when applying resistant exercise of lower extremity to stroke patients' gait, close kinetic chain is more effective than open kinetic chain.

• 대한물리의학회지
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• 제4권1호
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• pp.23-30
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• 2009

Purpose : This study was investigated the effect of static balance recovery during open kinetic chain exercise (OKC) and closed kinetic chain exercise(CKC). Methods : The paticipants were consisted of forty-one, was perform 3 sets, 3 times per week for 6 weeks, balance was measured by GOOD BALANCE. Statistical analysis was used repeated measure two-way ANOVA and independent t-test. Results : In CKC group, Center of presure(COP) medial-lateral(ML) velocity was significantly increased post 6 week test than pre-test, post 2 week test. COP anterior-posterior(AP) velocity was significantly increased post 6 week test than pre-test (p<.05). Conclusion : It was found that both OKC and CKC was significantly increased balance recovery in normal younng adults. In further study, it was suggested that was regard patient with muscle weakness.

• 한국전문물리치료학회지
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• 제26권2호
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• pp.49-60
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• 2019

Background: After stroke, in order to improve gait function, it is necessary to increase the muscle strength and to enhance the propriocetive function of the lower extremity. Objects: This study aimed to compare the effects of open kinetic chain (OKC) versus closed kinetic chain (CKC) isokinetic exercise of the hemiparetic knee using the isokinetic equipment on lower extremity sensorimotor function and gait ability in patients with chronic stroke. Methods: Thirty participants with chronic hemiplegia (> 6 months post-stroke) were randomly divided into 2 equal groups: CKC group and OKC group. Patients from both groups attended conventional physiotherapy sessions 3 times a week for 6 weeks. Additionally, subjects from the CKC group performed isokinetic exercise using the CKC attachment, while those from the OKC group performed isokinetic exercise using the OKC attachment. The isokinetic knee and ankle muscles strength, position sense of the knee joint, and spatiotemporal gait parameters were measured before and after interventions. Results: The knee muscles peak torque/body weight (PT/BW) and hamstring/quadriceps (H/Q) ratio significantly increased in both groups (p<.01). In particular, ankle plantarflexors PT/BW, position sense of the knee, gait velocity, and spatial gait symmetry significantly improved in the CKC group (p<.01, p<.05, p<.01, and p<.01, respectively). Conclusion: CKC isokinetic exercise can be an effective therapeutic intervention for the improvement of sensorimotor function of the lower extremity and gait functions, such as gait velocity and symmetry. CKC position in isokinetic strength training is effective to improve functional ability in patients with chronic stroke.

• 산업공학
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• 제22권2호
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• pp.153-164
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• 2009

An effective management for reverse flows of products such as reuse, repair and disposal, has become an important issue for every aspect of business. In this paper, we study the Location-Routing Problem (LRP) in the multi-stage closed-loop supply chain network. The closed-loop supply chain in this study integrated both forward and reverse flows. In forward flow, a factory, Distribution Center (DC) and retailer are considered as usual. Additionally in reverse flow, we consider the Central Returns collection Center (CRC) and disposal facility. We propose a mixed integer programming model for the design of closed-loop supply chain integrating both forward and reverse flows. Since the LRP belongs to an NP-hard problem, we suggest a heuristic algorithm based on genetic algorithm. For some test problems, we found the optimal locations and routes by changing the numbers of retailers and facility candidates. Furthermore, we compare the efficiencies between open-loop and closed-loop supply chain networks. The results show that the closed-loop design is better than the open one in respect to the total routing distance and cost. This phenomenon enlarges the cut down effect on cost as an experimental space become larger.

• 대한통합의학회지
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• 제7권2호
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• pp.165-179
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• 2019

Purpose : The purpose of this study is to improve the stroke patient's gait ability by applying a closed or kinetic chain lower limb exercise Methods : The study subjects were 48 hospitalized hemiplegic patients who agreed to participate in the study. 48 subjects went through the intervention: 24 in the experimental group and 24 in the control group. One set consisted of 10 repeats of the exercise. The subjects performed three sets of the exercise once a day, 5 times a week, for 6 weeks. Results : TUG and FGA were significantly improved in the experimental group. The spatio-temporal gait variables in the experimental group all showed significant improvement. In the control group, velocity, cadence, and double limb support showed significant improvement, Trunk sway angle showed significant improvement in all three axes in both groups. Conclusion : The results of this study indicate that a more positive effect in terms of improvement of the stroke patient's gait ability will be seen for closed rather than open kinetic chain lower limb resistance exercise.

• 대한통합의학회지
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• 제2권4호
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• pp.49-58
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• 2014

Purpose : The purpose of this study was to research the effects on resistance CKC & OCK exercise method on lower limb muscle activity, in chronic stroke patients. Method : In this study, 18 patients with stroke caused by hemorrhage or infarction were participated. resistance exercise method was conducted in tow different group : one is a close kinetic chain exercise(CKC) group and the other is an open kinetic chain exercise(OKC) group. CKC with physical therapy was applied to 9 patients, and OKC with physical therapy was applied to 9 patients. Under the researcher's guidance, exercise for CKC and OKC group carried out 3 times a week for 30 minutes during 4weeks. Result : There was significantly different for the vastus lateralis, tibialis anterior and gastrocnemius muscle activity within the intervention period both group. The vastus lateralis, tibialis anterior and gastrocnemius muscle activity was significantly increased within the CKC group. The vastus leteralis and tibialis anterior muscle activity was significantly increased within the OKC group. Conclusion : It was confirmed in this study that the CKC exercise was more effective than OKC exercise in improving lower limb muscle activity of chronic stroke patients. This study seggested that CKC may be suitable for individuals with a chronic stroke. furthermore study should be made a lot of researches regarding in other method and varying conditions for many hemiplegic patients.

• 대한물리의학회지
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• 제6권2호
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• pp.215-223
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• 2011

Purpose: The purpose of this study was to determine the effect of leg muscle activation by applying proprioceptive neuromuscular facilitation (PNF) arm patterns to unilateral upper extremities under the condition of both open and closed kinetic chains in a seated position. Methods: Twenty-two healthy subjects participated in this study. Four PNF patterns were applied to each subject's unilateral upper extremity. EMG data were collected from the vastus medialis, biceps femoris, tibialis anterior and gastrocnemius. The measured EMG data were digitized and processed to root mean square (RMS) and expressed as percentage maximal voluntary isometric contraction (%MVIC). The data were analyzed using two-way analysis of variance (ANOVA) with repeated measures to determine the statistical significance. Results: The results of this study were summarized as follows: Firstly, in comparison to muscle activation of the biceps femoris, there was a significant increase in the D2 flexion pattern when it was compared with D2 extension pattern and when it was compared with D1 flexion pattern (p<.05). Secondly, there was a significant increase in the muscle activation of the vastus medialis and tibialis anterior with a closed kinetic chain rather than an open kinetic chain (p<.05). Conclusion: In conclusion, in order to increase muscle activation of the biceps femoris, the D2 flexion pattern can be applied, regardless of kinetic chain. In addition, in order to increase muscle activation of the vastus medialis and tibialis anterior, four arm patterns can be applied with a closed kinetic chain.