• 대기
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• 제26권3호
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• pp.413-421
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• 2016

Climate Analysis Seoul (CAS) which provides gridded data relevant for thermal assessment was applied to one of the urban green areas, the Seonjeongneung, in Seoul, Korea. The thermal environment in the Seonjeongneung was evaluated from the CAS simulation for the five heat-wave issued cases during the last five years (2011~2015). The CAS has been improved continuously since it was developed. An updated version with a higher resolution of the CAS simulation domain and an addition of the vegetation information was used in this study. The influence of vegetation in the Seonjeongneung is estimated through the amount of the cold air generation ($Q_{ca}$) and air temperature deviation at each grid points, which are calculated by incorporating Geographic Information System (GIS) analysis on the simulation domain and meteorological analysis with the METeorology and atmospheric PHOtochemistry mesoscale MODel (MetPhoMod) in the CAS. The average amount of the cold air generation ($Q_{ca}$) at the Seonjeongneung is about $25.5m^3m^{-2}h^{-1}$ for the whole cases, and this value is similar to the ones in a forest or a well-wooded region. The average value of the total air temperature deviation (TD) is $-2.54^{\circ}C$ at the Seonjeongneung for the five cases. However, this cooling effect of the urban green area disappeared when the region is replaced by high-rise buildings in the CAS simulation. The $Q_{ca}$ drastically decreases to about $1.1m^3m^{-2}h^{-1}$ and the average TD shows an increase of $1.14^{\circ}C$ for the same events. This result shows that the vegetation in the Seonjeongneung supposes to keep down temperature during the heat-wave issued day and the average cooling effect of the green region is $3.68^{\circ}C$ quantitatively from the TD difference of the two simulations. The cooling effect represented with the TD difference is larger than $0.3^{\circ}C$ within 200 m distance from the boundary of the Seonjeongneung. Further improvements of the thermodynamical and advection processes above the model surface are required to consider more accurate assessment of the cooling effect for the urban green area.

• 한국산학기술학회논문지
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• 제12권6호
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• pp.2660-2667
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• 2011

TREK-1 채널은 two-pore 도메인 포타슘 (K2P) 채널로서 세포내 pH, 세포막의 신전, 불 포화 지방산, 온도, 휘발성 마취제, 신경세포방어물질에 의해 잘 조절된다. TREK-1 채널은 포타슘 이동에 의해 신경세포의 흥분성과 안정막전압을 조절한다. 최근 TREK-1은 전립선 암세포에서도 과발현됨이 확인되었다. 이러한 중요성에도 불구하고, TREK-1 채널에 대한 플라보노이드 효과는 거의 알려지지 않았다. 본 연구의 목적은 전기생리학적 방법 중의 하나인 excised inside-out patch기법을 이용하여 TREK-1 채널을 조절하는 플라보노이드를 탐색하는 것이다. TREK-1 채널이 발현된 CHO 세포에서 단일채널 팻취고정 방법을 이용하여 커큐민 (curcumin), EGCG (epigallocatechin-3-gallate), 퀘르세틴 (quercetin)에 의한 TREK-1 채널의 차단효과를 증명하였다. 퀘르세틴과 커큐민의 차단효과는 가역적으로 회복되었으나 EGCG는 거의 회복되지 않았다. 퀘르세틴, EGCG, 커큐민의 상대적 채널 활성도 (relative channel activity)는 $73{\pm}2.3%$ (n=5), $91{\pm}3.2%$ (n=7), $94{\pm}5.6%$ (n=4)까지 감소하였다. CHO 세포에 발현된 TREK-1 채널에 대한 커큐민, 퀘르세틴, EGCG의 $IC_{50}$는 각각 $1.04{\pm}0.19\;{\mu}M$, $1.13{\pm}0.26\;{\mu}M$, $13.5{\pm}2.20\;{\mu}M$ 이었다. 이러한 결과는 플라보노이드가 TREK-1 채널을 억제하며, 이 조절은 신경계 또는 종양세포에서 플라보노이드의 약리학적 작용 중의 하나임을 제시한다.

• 대한간호학회지
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• 제29권5호
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• pp.1058-1071
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• 1999

Although healthy lifestyles have been proved as an effective way of improving higher well-beings for individuals. researches on health-promoting behaviors of minority elderly with a specific ethnic heritage have been sparsely tried. This study was designed to explore health-promoting lifestyle patterns of Korean immigrant elderly living in Seattle, USA and its relationships with two associated perceptual variables, self-esteem and perceived health status. One hundred ten Korean immigrant elderly were recruited from two senior centers and interviewed with a structured questionnaire. Data were collected from October 1998 to January 1999, and analyzed using SPSS program through which t-test, ANOVA, and Pearson Correlation Coefficients were tested. As the results, the mean HPLP score of the Korean immigrant elderly was 2.54 (SD ＝ .36), showing significant differences by education (F ＝ 3.61, P ＝ .016), economic status (F ＝ 3.01, P ＝ .034), and current health status (F ＝ 3.69, p ＝ .008). In self-esteem, two socioeconomic variables showed statistical association with self-esteem : marital status (t ＝ 2.47, P ＝ .015) and living situation (F ＝ 4.03, p ＝ .021). The HPLP subscales that showed higher mean scores were nutrition (M ＝ 3.01, SD ＝ .52) and interpersonal support (M ＝ 2.65, SD ＝ .47) while lower mean scores were detected in the domain of exercise (M ＝ 1.92, SD ＝ .74) and stress management (M ＝ 2.26, SD ＝ .47). Perceived health status revealed significant positive correlation with health-promoting lifestyle patterns (r ＝ .19, P ＝ .043) and self-esteem (r ＝ .32, P ＝ .001) in the present study. It is concluded that engagement in health-promoting lifestyle patterns should be actively encouraged to enhance personal health of Korean immigrant elderly. Developing health promotion programs focused on exercise and stress management is also imperatively suggested not only for better health practices of Korean immigrant elderly population but also for enhancing their level of well-beings and life satisfaction.

• Journal of Magnetics
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• 제9권2호
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• pp.40-46
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• 2004

The magnetic properties of sputtered ($Ni_{83}Fe_{17}/Au/Co/Au$) multilayers with various thicknesses of Au (0.5 {\leq} t_{Au} {\leq} 3 nm), Ni-Fe ($1{\leq}t_{Ni-Fe}{\leq}4nm$) and Co ($0.2{\leq}t_{co}{\leq}1.5nm$) layers were characterized. An alternating in-plane and out-of-plane anisotropy of the ferromagnetic layers was achieved for the structures ($t_{Au}{\geq}1.5nm$) showing a weak coupling between the Ni-Fe layers with an in-plane anisotropy and the Co layers ($0.3{\leq}t_Co{\leq}1.2nm$) with a perpendicular anisotropy. For such a structure, a detailed discussion on the GMR effect is presented, relating to the magnetization reversal from a mutually perpendicular magnetic configuration at the remanence to a parallel one at the saturation. An influence of the dense labyrinth domain structure on the magnetoresistance effect is also addressed.

• 천문학회보
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• 제39권2호
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• pp.40-40
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• 2014

Through KASI, Korean astronomers will have access to the Gemini Observatory starting in 2015. Gemini operates two optical/infrared 8m-class telescopes: one on the northern hemisphere in Hawaii, one on the southern hemisphere in Chile. Both are equipped with state of the art instruments and adaptive optics systems that will be presented. Gemini also offers the opportunity for instrument development and welcomes visiting instruments. In terms of operations, Gemini offers to its partners three ways of applying for time: through semester-basis calls for standard programs, through yearly calls for Large and Long Programs, and through monthly calls for fast turnaround programs. Gemini operates in queue mode (observing for the principal investigators and allowing flexibility in the time domain), as well as in the classical visitor mode (where principal investigators come to the telescope). I will explain the requirements and advantages of all these modes as well as a full update on the Gemini Observatory.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 1999년도 추계 학술대회논문집
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• pp.71-76
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• 1999

The base flow regions of a three-body sounding rocket containing multiple exhaust plumes were numerically investigated in three dimensions for a free stream Mach number of 2.7 at flight altitude 18.5 km. The flowfields were calculated using the full compressible Navier-Stokes equations with an one-equation turbulence model of Baldwin-Earth. The present calculations were executed based upon a chemically frozen, single perfect gas model assumption. Due to the symmetry of the three-body rocket of each single nozzle, only one fourth of the computational domain was considered for the analysis. The results indicate that a babe heating effect is not considerable due to the small expansion of the plumes. In the base, however, a low speed recirculating flow dominates the region.

• 한국생활과학회지
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• 제5권2호
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• pp.37-52
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• 1996

The purpose of this study was to explore the nature of parent education programs for fathers with children aged 1 through 5 year-old. One-Hundred forty-four fathers were answered using questionaire designed to elicit their perception of fathering, the details of domain parent education, and parent education program. Data were analyzed quantitatively and qualitatively to determine the contents of parent education program as perceived by the fathers. The results of this study were as follows; 1. Fathers perceived about parent education as 'The training of living behavior', 'The education about essential method of living manners and the guidance for children.' Also, fathers commented some difficult points of raising children as; 'children' sickness', 'Parents' permission or control', and 'Childrens' stubborness'. Many fathers pointed their shortages; 'to be a model of habit and behavior', 'Lacking of enough experience and imagination to their children', and 'Limiting parent's patience to their children'. 2. On the domain of parent education, six subscales of requisite degree was very high. The highest requisite domains like three questions of 34 subordinate question was; 'to encourage their children their children', knowledge about how to develop children' emotions', 'knowledge of their influence to their children' humanity'. 3. Fathers answered that a parent education was needed in infant period. They choose suitable time and place, from p.m.6 to p.m. 9 on a day and once in a week in the kindergarten. Also, the contents of parent education program were needed in order as follows; 'Communication method with a child', 'Formation of living behavior'. Moreover, 77.6% of fathers wanted to participate in the parent education program.

• 동력기계공학회지
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• 제13권5호
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• pp.25-33
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• 2009

In the present study, the numerical investigation has been carried out to see the effects of water mist sprays on the fire suppression mechanism. The special-purposed program named as FDS was used to simulate the interaction of fire plume and water mists. This program solves the fire-driven flows using LES turbulence model, the mixture fraction combustion model, the finite volume method of radiation transport for a non-scattering gray gas, and conjugate heat transfer between wall and gas flow. The computational domain was composed of a rectangular space dimensioned as $L{\times}W{\times}H=4.0{\times}4.0{\times}2.5\;m^3$ with a mist-injecting nozzle installed 1.0 m high from the fire pool. In this paper, two types of nozzles were chosen to compare the performance of the fire suppression. Numerical results showed that the nozzle, type A, with more orifices having smaller diameters had poorer performance than the other one, type B because the flow injected through side holes deteriorated the primary flow. The fire-extinguishing time of type A was 2.6 times bigger than that of type B.

• 생명과학회지
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• 제25권10호
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• pp.1103-1109
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• 2015

뇌 해마의 콜린성 신경분포는 학습과 기역에 연관성이 있는 것으로 알려져 있으며 이의 작용제인 carbachol 투여 시 장기기억 저하가 유도됨이 알려져 왔다. 그러나 이러한 콜린성 자극에 의한 해마 신경세포의 시냅스 내 변화기작은 완전히 알려지지 않고 있다. 본 연구에서는 아세틸콜린 수용체의 활성에 의하여 유도되는 장기기억 저하 현상에 있어 alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) 수용체가 후시냅스 표면으로부터 사라지는 현상과 이의 조절기작에 대하여 알아보고자 한다. 이를 위하여 쥐 해마의 일차세포를 추출하고 체외에서 배양한 성숙 신경세포에 carbachol 을 투여하여 장기기억 저하를 유도 하였으며, 후시냅스의 표면으로부 터 AMPA 수용체의 아단위체인 GluA2가 M1 무스카린 수용체의 길항제에 의하여 저해 되었다. 또한 콜린성 자극 에 의한 GluA2의 내재화 현상의 작용기작 연구를 위하여 쥐 해마 절편에 carbachol 투여 후 GluA2와 직접적인 상호작용을 하는 Glutam내재화 되었음을 확인하였다. 이러한 현상은 ate receptor-interacting protein 1 (GRIP1) 과 clathrine 단백질이 매개하는 세포내이입 작용을 하는 adaptin-α 단백질의 결합 변화를 관찰하였다. GluA2는 carbachol 자극에 의해 세포내이입 과정에서 adaptin-α 와의 결합이 증가하였으며 반대로 GRIP1과는 해리되었다. 이는 아세틸콜린의 수용체의 자극에 의하여 GluA2의 내제화 작용이 수반되며, 이의 작용기작으로 GluA2의 후시 냅스 표면 발현시에 결합하고 있는 GRIP1과 해리 되면서 장기기억 저하 현상이 유도됨을 의미한다.

• Bulletin of the Korean Chemical Society
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• 제18권8호
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• pp.831-840
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• 1997

Core/shell structured composite metal oxides of Fe2O3/MgO were prepared by thermal decomposition of Fe(acac)3 adsorbed on the surface of MgO cores. The morphology of the composites conformed to that of the MgO used as the cores. Broad powder X-ray diffraction peaks shifted toward larger d, large BET surface area (∼350 m2/g), and the size of crystalline domains in nano range (4 nm), all corroborate to the nanocrystallinity of the Fe2O3/MgO composite which was prepared by using nanocrystalline MgO as the core. By use of microcrystalline MgO as the core, microcrystalline Fe2O3/MgO composite was prepared, and it had small BET surface area of less than 35 m2/g. AFM measurements on nanocrystalline Fe2O3/MgO showed a collection of spherical aggregates (∼80 nm dia) with a very rough surface. On the contrary, microcrystalline Fe2O3/MgO was a collection of plate-like flat crystallites with a smooth surface. The nitrogen adsorption-desorption behavior indicated that microcrystalline Fe2O3/MgO was nonporous, whereas nanocrystalline Fe2O3/MgO was mesoporous. Bimodal distribution of the pore size became unimodal as the layer of Fe2O3 was applied to nanocrystalline MgO. The macropores in a wide distribution which the nanocrystalline MgO had were absent in the nanocrystalline Fe2O3/MgO. The decomposition of CCl4 was largily enhanced by the overlayer of Fe2O3 on nanocrystalline MgO making the reaction between nanocrystalline Fe2O3/MgO and CCl4 be nearly stoichiometric. The reaction products were environmentally benign MgCl2 and CO2. Such an enhancement was not attainable with the microcrystalline samples. Even for the nanocrystalline MgO, the enhancement was not attained, if not with the Fe2O3 layer. Without the layer of Fe2O3, it was observed that the nanocrystalline domain of the MgO transformed into microcrystalline one as the decomposition of CCl4 proceeded on its surface. It appeared that the layer of Fe2O3 on the particles of nanocrystalline Fe2O3/MgO blocked the transformation of the nanocrystalline domain into microcrystalline one. Therefore, in order to attain stoichiometric reaction between CCl4 and Fe2O3/MgO core/shell structured composite metal oxide, the morphology of the core MgO has to be nanocrystalline, and also the nanocrystalline domains has to be sustained until the core was exhausted into MgCl2.