• Title/Summary/Keyword: off-target

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An Object-Level Feature Representation Model for the Multi-target Retrieval of Remote Sensing Images

  • Zeng, Zhi;Du, Zhenhong;Liu, Renyi
    • Journal of Computing Science and Engineering
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    • v.8 no.2
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    • pp.65-77
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    • 2014
  • To address the problem of multi-target retrieval (MTR) of remote sensing images, this study proposes a new object-level feature representation model. The model provides an enhanced application image representation that improves the efficiency of MTR. Generating the model in our scheme includes processes, such as object-oriented image segmentation, feature parameter calculation, and symbolic image database construction. The proposed model uses the spatial representation method of the extended nine-direction lower-triangular (9DLT) matrix to combine spatial relationships among objects, and organizes the image features according to MPEG-7 standards. A similarity metric method is proposed that improves the precision of similarity retrieval. Our method provides a trade-off strategy that supports flexible matching on the target features, or the spatial relationship between the query target and the image database. We implement this retrieval framework on a dataset of remote sensing images. Experimental results show that the proposed model achieves competitive and high-retrieval precision.

A Combined Process Control Procedure by Monitoring and Repeated Adjustment

  • Park, Changsoon
    • Communications for Statistical Applications and Methods
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    • v.7 no.3
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    • pp.773-788
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    • 2000
  • Statistical process control (SPC) and engineering process control (EPC) are based on different strategies for processes quality improvement. SPC reduces process variability by detecting and eliminating special causes of process variation. while EPC reduces process variability by adjusting compensatory variables to keep the quality variable close to target. Recently there has been needs for a process control proceduce which combines the tow strategies. This paper considers a combined scheme which simultaneously applies SPC and EPC techniques to reduce the variation of a process. The process model under consideration is an integrated moving average(IMA) process with a step shift. The EPC part of the scheme adjusts the process back to target at every fixed monitoring intervals, which is referred to a repeated adjustment scheme. The SPC part of the scheme uses an exponentially weighted moving average(EWMA) of observed deviation from target to detect special causes. A Markov chain model is developed to relate the scheme's expected cost per unit time to the design parameters of he combined control scheme. The expected cost per unit time is composed of off-target cost, adjustment cost, monitoring cost, and false alarm cost.

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Target Tracking Algorithm Using Fuzzy Neural Network (퍼지 신경망을 이용한 표적 추적 알고리듬)

  • Lee, Jin-Whan;Chang, Wook;Kwon, Ok-Kook;Joo, Young-Hoon;Park, Jin-Bae
    • Proceedings of the KIEE Conference
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    • 1998.07b
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    • pp.575-577
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    • 1998
  • In this paper, we propose a hybrid target tracking algorithm which combine the conventional Kalman filter algorithm and the fuzzy neural network. Conventional methods are degraded in the presence of uncertanties and the environmental noise. These problems can be resolved by the proposed method. The training data for the proposed target tracker is obtained by the off-line simulation. Unlike other target trackers usging fuzzy inference system, our method can be easily integrated into the existing system. A numerical simulation is included to show the effectiveness and the feasibility of the proposed method.

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Methods for environmental risk assessment of rice transgenic plants expressing small non-coding RNA (Small non-coding RNA를 발현하는 형질전환 벼의 환경위해성 평가 방법)

  • Jin, Byung Jun;Chun, Hyun Jin;Cho, Hyun Min;Lee, Su Hyeon;Choi, Cheol Woo;Jung, Wook-Hun;Baek, Dongwon;Han, Chang-deok;Kim, Min Chul
    • Journal of Plant Biotechnology
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    • v.46 no.3
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    • pp.205-216
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    • 2019
  • Since the RNA interference (RNAi) had been discovered in many organisms, small non-coding RNA-mediated gene silencing technology, including RNAi have been widely applied to analysis of gene function, as well as crop improvement. Despite the usefulness of RNAi technology, RNAi transgenic crops have various potential environmental risks, including off-target and non-target effects. In this study, we developed methods that can be effectively applied to environmental risk assessment of RNAi transgenic crops and verified these methods in 35S::dsRNAi_eGFP rice transgenic plant we generated. Off-target genes, which can be non-specifically suppressed by the expression of dsRNAi_eGFP, were predicted by using the published web tool, pssRNAit, and verified by comparing their expressions between wild-type (WT) and 35S::dsRNAi_eGFP transgenic rice. Also, we verified the non-target effects of the 35S:: dsRNAi_eGFP plant by evaluating horizontal and vertical transfer of small interfering RNAs (siRNAs) produced in the 35S::dsRNAi_eGFP plant into neighboring WT rice and rhizosphere microorganisms, respectively. Our results suggested that the methods we developed, could be widely applied to various RNAi transgenic crops for their environmental risk assessment.

Characteristics of Carbon-Doped Mo Thin Films for the Application in Organic Thin Film Transistor (유기박막트랜지스터 응용을 위한 탄소가 도핑된 몰리브덴 박막의 특성)

  • Dong Hyun Kim;Yong Seob Park
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.36 no.6
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    • pp.588-593
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    • 2023
  • The advantage of OTFT technology is that large-area circuits can be manufactured on flexible substrates using a low-cost solution process such as inkjet printing. Compared to silicon-based inorganic semiconductor processes, the process temperature is lower and the process time is shorter, so it can be widely applied to fields that do not require high electron mobility. Materials that have utility as electrode materials include carbon that can be solution-processed, transparent carbon thin films, and metallic nanoparticles, etc. are being studied. Recently, a technology has been developed to facilitate charge injection by coating the surface of the Al electrode with solution-processable titanium oxide (TiOx), which can greatly improve the performance of OTFT. In order to commercialize OTFT technology, an appropriate method is to use a complementary circuit with excellent reliability and stability. For this, insulators and channel semiconductors using organic materials must have stability in the air. In this study, carbon-doped Mo (MoC) thin films were fabricated with different graphite target power densities via unbalanced magnetron sputtering (UBM). The influence of graphite target power density on the structural, surface area, physical, and electrical properties of MoC films was investigated. MoC thin films deposited by the unbalanced magnetron sputtering method exhibited a smooth and uniform surface. However, as the graphite target power density increased, the rms surface roughness of the MoC film increased, and the hardness and elastic modulus of the MoC thin film increased. Additionally, as the graphite target power density increased, the resistivity value of the MoC film increased. In the performance of an organic thin film transistor using a MoC gate electrode, the carrier mobility, threshold voltage, and drain current on/off ratio (Ion/Ioff) showed 0.15 cm2/V·s, -5.6 V, and 7.5×104, respectively.

Shape Optimization of Cut-Off in a Multi-blade Fan/Scroll System Using Neural Network (신경망 최적화 기법을 이용한 다익 홴/스크롤 시스템의 설부에 대한 형상 최적화)

  • Han, Seog-Young;Maeng, Joo-Sung;Yoo, Dal-Hyun;Jin, Kyong-Uk
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.26 no.10
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    • pp.1341-1347
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    • 2002
  • In order to improve efficiency of a system with three-dimensional flow characteristics, this paper presents a new method that overcomes three-dimensional effects by using two-dimensional CFD and neural network. The method was applied to shape optimization of cut-off in a multi-blade fan/scroll system. As the entrance conditions of two-dimensional CFD, the experimental values at the positions out of the inactive zone were used. The distributions of velocity and pressure obtained by two-dimensional CFD were compared with those of three-dimensional CFD and experimental results. It was found that the distributions of velocity and pressure have qualitative similarity. The results of two-dimensional CFD were used for teaming as target values of neural network. The optimal angle and radius of cut-off were determined as 71$^{\circ}$and 0.092 times the outer diameter of impeller, respectively. It is quantified in the previous report that the optimal angle and radius of cut-off are approximately 72$^{\circ}$and 0.08 times the outer diameter of impeller, respectively.

EFFECT OF PLASTICIZERS ON THE PROPERTIES OF COSMETIC MASK USING POLYVINYL ALCOHOL(PVA) AS A FILM FORMER

  • Park, J.H.;Kyong, K.Y.;Kwak, T.J.;Yoon, M.S.;Kang, S.H.
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.25 no.4 s.34
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    • pp.51-55
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    • 1999
  • Cosmetic mask is one of the traditional cosmetic product and is used to keep skin healthy and beautiful through moisturizing effect, cleansing effect and acceleration effect on microcirculation. There are several types of cosmetic mask such as peel-off type, tissue-off type, wash-off type and cotton sheet type immersed in cosmetic water. It is important for cosmetic formulators to develop an adequate type of cosmetic mask that meets the needs of the target consumers because each type of cosmetic mask has benefits and problems in its usage and efficacy. Polyvinyl alcohol (PVA) is widely used as an active ingredient of peel-off type cosmetic mask and the physical property of the PVA film changes with the usage of other ingredients. We studied the change of physical properties of the film containing PVA by formulating peel-off type cosmetic mask with the variation of humectants. Methylguceth-20 and glycereth-26 reduce the interaction between skin surface and PVA film without serious weakening of tensile strength and they can alleviate irritation. Glycerin, urea and betaine help PVA film soften and they also have excellent efficacy as humectants.

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How to Use an Optimization-Based Method Capable of Balancing Safety, Reliability, and Weight in an Aircraft Design Process

  • Johansson, Cristina;Derelov, Micael;Olvander, Johan
    • Nuclear Engineering and Technology
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    • v.49 no.2
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    • pp.404-410
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    • 2017
  • In order to help decision-makers in the early design phase to improve and make more cost-efficient system safety and reliability baselines of aircraft design concepts, a method (Multi-objective Optimization for Safety and Reliability Trade-off) that is able to handle trade-offs such as system safety, system reliability, and other characteristics, for instance weight and cost, is used. Multi-objective Optimization for Safety and Reliability Trade-off has been developed and implemented at SAAB Aeronautics. The aim of this paper is to demonstrate how the implemented method might work to aid the selection of optimal design alternatives. The method is a three-step method: step 1 involves the modelling of each considered target, step 2 is optimization, and step 3 is the visualization and selection of results (results processing). The analysis is performed within Architecture Design and Preliminary Design steps, according to the company's Product Development Process. The lessons learned regarding the use of the implemented trade-off method in the three cases are presented. The results are a handful of solutions, a basis to aid in the selection of a design alternative. While the implementation of the trade-off method is performed for companies, there is nothing to prevent adapting this method, with minimal modifications, for use in other industrial applications.

EFFECT OF PLASTICIZERS ON THE PROPERTIES OF COSMETIC MASK USING POLYVINYL ALCOHOL (PVA) AS A FILM FORMER

  • Park, J.H.;K.Y.Kyong;Kwak, T.J.;Yoon, M.S.;Kang, S.H.
    • Proceedings of the SCSK Conference
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    • 1999.10a
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    • pp.51-55
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    • 1999
  • Cosmetic mask is one of the traditional cosmetic product and is used to keep skin healthy and beautiful through moisturizing effect, cleansing effect and acceleration effect on microcirculation. There are several types of cosmetic mask such as peel-off type, tissue-off type, wash-off type and cotton sheet type immersed in cosmetic water. It is important for cosmetic formulators to develop an adequate type of cosmetic mask that meets the needs of the target consumers because each type of cosmetic mask has benefits and problems in its usage and efficacy. Polyvinyl alcohol (PVA) is widely used as an active ingredient of peel-off type cosmetic mask and the physical property of the PVA film changes with the usage of other ingredients. We studied the change of physical properties of the film containing PVA by formulating peel-off type cosmetic mask with the variation of humectants. Methylguceth-20 and glycereth-26 reduce the interaction between skin surface and PVA film without serious weakening of tensile strength and they can alleviate irritation. Glycerin, urea and betaine help PVA film soften and they also have excellent efficacy as humectants.

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Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast

  • Lee, Sol;Nam, Miyoung;Lee, Ah-Reum;Lee, Jaewoong;Woo, Jihye;Kang, Nam Sook;Balupuri, Anand;Lee, Minho;Kim, Seon-Young;Ro, Hyunju;Choi, Youn-Woong;Kim, Dong-Uk;Hoe, Kwang-Lae
    • Biomolecules & Therapeutics
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    • v.29 no.2
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    • pp.234-247
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    • 2021
  • We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol synthesis via the Erg1 enzyme. We identified 14 heterozygous strains corresponding to 10 non-essential [7 ribosomal-protein (RP) coding genes, spt7, spt20, and elp2] and 4 essential genes (tif302, rpl2501, rpl31, and erg1). Expectedly, their erg1 mRNA and protein levels had decreased compared to the control strain SP286. When we studied the action mechanism of the non-essential target genes using cognate haploid deletion strains, knockout of SAGA-subunit genes caused a down-regulation in erg1 transcription compared to the control strain ED668. However, knockout of RP genes conferred no susceptibility to ergosterol-targeting antifungals. Surprisingly, the RP genes participated in the erg1 transcription as components of repressor complexes as observed in a comparison analysis of the experimental ratio of erg1 mRNA. To understand the action mechanism of the interaction between the drug and the novel essential target genes, we performed isobologram assays with terbinafine and econazole (or cycloheximide). Terbinafine susceptibility of the tif302 heterozygous strain was attributed to both decreased erg1 mRNA levels and inhibition of translation. Moreover, Tif302 was required for efficacy of both terbinafine and cycloheximide. Based on a molecular modeling analysis, terbinafine could directly bind to Tif302 in yeasts, suggesting Tif302 as a potential off-target of terbinafine. In conclusion, this genome-wide screening system can be harnessed for the identification and characterization of target genes under any condition of interest.