• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.3
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• pp.110-117
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• 2015

All infants should be screened for phenylketonuria (PKU) within the three days of life, in order to allow timely dietary intervention to protect children with PKU from neurologic damage in Korea. A commonly used cut-off level for diagnosis of PKU is $240{\mu}mol/L$ (4 mg/dL). Up to 2% of cases of hyperphenylalaninemias (HPA) detected by the screening test will account for a disorder of $BH_4$ metabolism. Therefore, analysis of blood or urinary pterins is essential, backed up with measurement of DHPR activity, as this allows differentiation of $BH_4$ disorders. A $BH_4$ loading test and measurement of neurotransmitters in CSF provide further important information to the severity of $BH_4$ deficiency and $BH_4$ loading test can detect patients with $BH_4$ deficiency and $BH_4$ responsive PKU. Several protocols for $BH_4$ loading test have been described, involving treatment with $BH_4$ for periods ranging from 1 day to 1 month, and using doses of $BH_4$ of 10-20 mg/kg. There is general agreement that a reduction on blood phenylalanine of at least 30% in response to $BH_4$ loading indicates a clinically significant effect, although in some tests a lower cut-off value may be defined for individual patients, or no specific cut-off value is proposed. The frequency of $BH_4$ responsiveness is highest in patients with mild HPA and mild to moderate PKU resulting from PAH mutations with residual activity.

• International Journal of Costume and Fashion
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• v.15 no.2
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• pp.19-36
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• 2015

The purpose of this study is to research the purchasing behavior according to the pursuit benefit for outdoor wear and to present a direction to outdoor wear. Questionnaire survey was administered to 533 male and female adults in their 30s to 40s living in Seoul and Gyeonggido from May 1 to 15, 2014. Concerning the statistic treatment for data analysis, SPSS for Window 18.0 was used to carry out frequency analysis, factor analysis, reliability test, cluster analysis, ANOVA and Duncan test as post-test. Benefit was drawn out as 4 elements including 'showing off & brand benefit sought', 'fashion benefits sought', 'functionality benefits sought' and 'economic benefits sought'. Group analysis according to benefit showed that it was materialized to 'multiple benefit sought group', 'unconcern group', 'showing off & brand benefit sought group' and 'utility benefit sought group'. There is an academic significance in that this research found out the level of benefit in purchasing outdoor wear and the difference of purchasing behavior by consumer groups according to benefit. This result might be used efficiently by marketers in outdoor clothing industry in classifying consumers and establishing the marketing strategy to deal with it.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.16 no.3
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• pp.1-6
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• 2008

The stalling speed flight test of light airplane, ChangGong-91, was performed to acquire the certification. With power-off engine condition, the wings level stall flight tests were conducted at the aircraft configuration of various flap angle - clean, 20degree, and full flap, respectively. They were performed considering with the combination of the maximum and minimum test weight, and forward and afterward center of gravity. The stalling speeds and the minimum speeds of light airplane were determined from the results of flight test. Also, the appropriateness of stall warning speeds are evaluated through the flight test measures. The airplane is recoverable only with pitch control and engine throttle from stall state without exceptional operation.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.3
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• pp.132-142
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• 2023

Human leukocyte antigen (HLA) typing was performed in the diagnostic immunology laboratory of the Seoul National University Hospital. Among 611 HLA-DR tests, specific bead reactions suspected of being false positive and false negative in Lot 20 reagents were found. Therefore, we aimed to identify the factors causing cut-off corrections by examining cases where cut-off corrections were not made for 533 test results and cases where cut-off corrections were made for 78 cases after the cut-off corrections of specific beads. Frequency analysis was conducted to verify the demographic characteristics, and descriptive statistics were used to assess the humidity in the laboratory as a variable. Cross-tabulation was done to examine the association between cut-off corrections and demographic characteristics. Independent samples t-tests were conducted to verify the difference in humidity based on cut-off corrections. Finally, logistic regression analysis was conducted to examine the relationship between humidity levels and the rate of cut-off corrections, and results showed as the humidity level in the laboratory highs, the number of cut-off corrections decreased by a factor of 0.986. This suggests cut-off corrections rate increases when the humidity lowers. Therefore, it indicates that humidity in the laboratory is also a factor that affects HLA typing results.

• Korean Journal of Applied Biomechanics
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• v.25 no.1
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• pp.1-10
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• 2015

Objective : The purpose of this study was to find some kinetic variable's relationships between personal records and low records in female high jump. Methods : Collected data of the subjects(N=8, ages: $25.5{\pm}1.85$, height: $173{\pm}5.83$, mass: $54.75{\pm}6.36$ personal record: $1.71{\pm}0.04$, low record: $1.62{\pm}0.03$) were used for the last three strides and take-off phase. Five video cameras set in 30frames/s were used for recording. After digitizing motion, the Direct Linear Transformation(DLT) technique was employed to obtain 3-D position coordinates. The kinematic and kinetic factors of distance, velocity, angle, impulse, jerk variables were calculated. A paired t-test was applied for the difference of variables between personal records and lower records and for correlation with performances and variables. The significance level was accepted at p<.05. Results : There was no relationship between pattern of stride and performance. However, rate of change of velocity was related with cental of mass height(CMH) at peak point(PP). Knee, hip, backward lean, foot plant, approach and take off angle showed no difference between best record and low record. Vertical impulse momentum also showed no difference between performances. Conclusion : According to a t-test result, there were significant differences in CMH at PP and jerk at touch down between best record and low record.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.31A no.9
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• pp.146-155
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• 1994

In this paper, we desribe a new system, called BEST, that is used to develop a macromodel or behavioral model easily. It automatically calculates the component values of macromodel represented by equations to satisfy the given specification. Also, it gives the way to analyze both the behavioral model and transistor level circuit, and then compare the analysis results of them to check the correspondence under specific temperature and bias condition, and BEST optimizes the component values of macromodel. Other feature is to characterize MOSFET as switch model which consists of PWL-RC network. Finally, it is possible to generage multi-level netlist which consists of macro/switch/transistor level circuits, and user can determine the trade-off between simulation speed and accuracy. With the graphic user interface form of macromodel development system described above. BEST enable designers to make macromodel by themselves and to uas it. We applied BEST to develop the macromodel for the test circuit and got the 18.6 times simulation speed up with preserving the accuracy within 10% compared to the conventional transistor level circuit simulation. Also, applicability of optimization capability was verified.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.30 no.2
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• pp.125-131
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• 1994

This paper describes a method to measure the distortion level of loudspeaker using a LMS(Least Mean Square) adaptive filter. Conventional technique to measure the distortion level uses a band-pass filter with a sharp cut-off frequency characteristics. However. such the band-pass filter has a bed time response characteristics. On the other hand, the proposed method offers us an easy way to measure the specified harmonic distortion level with a small hardware. Moreover, our method is not affected by noise which has no correlation with the test signal, and the measurement can be carried out in a noisy environment. The effectiveness of the proposed method is confirmed by experiment using a loudspeaker in a noisy room.

• Kosin Medical Journal
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• v.33 no.3
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• pp.337-346
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• 2018

Objectives: Serum procalcitonin (PCT) is a specific biomarker that rises after bacterial infection, and levels of PCT are known to correlate with the severity and mortality of patients with pneumonia and sepsis. However, the usefulness of PCT levels in acute pyelonephritis is unknown. This study aimed to evaluate the effectiveness of using the PCT level as a predictive test for bacteremia in acute pyelonephritis. Methods: Between January 2012 and June 2013, 140 patients diagnosed with acute pyelonephritis were admitted to Haeundae Paik Hospital. Serum PCT, C-reactive protein (CRP), and white blood cell (WBC) levels at pre- and post- treatment were measured. Blood and urine cultures were obtained from all patients. The levels of PCT, CRP, and WBCs were each compared between the blood culture-positive and blood culture-negative groups to assess their effectiveness in predicting bacteremia. Results: Pre-treatment PCT level was 0.77 ng/mL (95% CI: 0.42-1.60 ng/mL) in the blood culture-negative group and 4.89 ng/mL (95% CI: 2.88-9.04 ng/mL) in the blood culture-positive group, and the increase between the two groups was statistically significant. The area under the receiver operating characteristic curve of PCT level for prediction of bacteremia was 0.728. A cut-off value of 1.23 ng/mL indicated a sensitivity of 79.0 % and specificity of 60.0 % for PCT level. Conclusions: Serum PCT level is a useful predictive test for bacteremia in acute pyelonephritis. Through the early detection of bacteremia, serum PCT level can help estimate the prognosis and predict complications such as sepsis.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5695-5699
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• 2012

We investigated the relationships between demographics, lifestyle characteristics, and serum total prostate specific antigen (PSA) concentration and examined the population-based distribution of total PSA by age among 2,246 Korean men with a median age of 45 years. We obtained data about demographic and lifestyle characteristics based on self-reporting using a quetionnaire. We also performed physical examinations, anthropometric measurements, and biochemical measurements. The PSA concentration increased with age and there was a significant difference in total PSA concentration between the age groups of 21-60 years and >60 years. Age >60 years, height ${\geq}1.8$ m, a low frequency of alcohol consumption, and taking nutritional supplements showed a significantly increased odds ratio for increased PSA when 3.0 ng/mL was chosen as the PSA cut-off level. Smoking status, BMI, percent body fat, diabetes mellitus, fatty liver, herbal medicine use, vitamin use, and diet were not significantly associated with total PSA regardless of the cut-off level. When interpreting a single PSA test, height, alcohol consumption, and nutritional supplement use should be considered, in addition to age.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.2
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• pp.9-20
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• 2020

The study investigates a recent surge of cash literature by using a sample of hospitality firms to gain a new understanding of corporate cash holdings. Past literature states that there is a substantial variation of liquidity across industry groups. Existing literature predominantly refers to US-listed firms and focus on either hotels or restaurants and not the hospitality industry as a whole. Therefore, we provide a comparative study of cash holdings behaviour between hospitality and non-hospitality firms from an emerging market context. Using a sample of public listed hospitality firms from 2002 to 2013, dynamic panel regression techniques are used to study the relationships between firm characteristics and cash levels. Also, the non-parametric Wilcoxon-Mann-Whitney test was carried out to examine the time and sectoral differences in cash holdings. In addition, the panel regression techniques are used to investigate the relationships between firm characteristics and level of corporate cash holdings. The results reveal that firm characteristics do matter in hospitality firms. We find that firm size, capital expenditures, and liquid assets substitutes are negatively related to cash level. The results support trade-off theory and the pecking order theory. This study incrementally explains the cash holdings behaviour of hospitality firms in emerging market.