• Journal of Yeungnam Medical Science
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• 제33권1호
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• pp.8-12
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• 2016

Background: The decision to administer oral anticoagulation therapy depends on accurate assessment of stroke risk in patients with atrial fibrillation (AF). Various stroke risk stratification schemes have been developed to help inform clinical decision making. The CHADS2 and CHA2DS2-VASc scores have been used in estimating the risk of stroke in patients with AF. Recently R2CHA2DS2-VASc score was developed. The objective of the current study is to validate the usefulness of the R2CHA2DS2-VASc score and to compare the accuracy of the CHADS2, CHA2DS2-VASc, and R2CHA2DS2-VASc scores in predicting a patient's risk of stroke. Methods: Based on medical records, we conducted a retrospective study of patients hospitalized with AF from March 2011 to July 2013. A total of 448 AF patients were included in this study. The receiver operating characteristic (ROC) curve analysis in MedCalc was used for comparison with respective diagnostic values. Results: The patient characteristics showed male predominance (60.9%). Among the 448 AF patients, 131 (29.2%) patients had strokes during the study. A R2CHA2DS2-VASc score of more than 5 is the optimal cut-off value for prediction of stroke. A risk score of three, the area under the ROC curve (AUC) of R2CHA2DS2-VASc score (AUC 0.631; 95% confidence interval, 0.585-0.679) was the highest. A significant difference was observed between AUC for R2CHA2DS2-VASc, CHADS2, and CHA2DS2-VASc scores, but no meaningful difference between CHADS2 and CHA2DS2-VASc scores. Conclusion: We determined the usefulness of the R2CHA2DS2-VASc score, which showed better association with stroke than the CHADS2 and CHA2DS2-VASc scores.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7621-7628
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• 2013

Human epidermal growth factor receptor (HER) status is an important prognostic factor in breast cancer. There is no globally accepted method for determining its status, and which method is most precise is still a matter of debate. We here analyzed HER2 mRNA expression by quantitative reverse transcription-PCR (qRT-PCR) and HER2 DNA amplification using multiplex ligation-dependent probe amplification (MLPA). In parallel, we performed a routine evaluation of HER2 protein by immunohistochemistry (IHC). To assess the accuracy of the RT-PCR and MLPA techniques, a combination of IHC and fluorescence in situ hybridization (FISH) was used, substituting FISH when the results of IHC were ambiguous (2+) and for those IHC results that disagreed with MLPA and qRT-PCR, this approach being termed IHC-FISH. The IHC results for four samples were not compatible with the MLPA and qRT-PCR results; the MLPA and qRT-PCR results for these samples were confirmed by FISH. The correlations between IHC-FISH and qRT-PCR or MLPA were 0.945 and 0.973, respectively. The ASCO/CAP guideline IHC/FISH correlation with MLPA was (0.827) and with RT-PCR was (0.854). The correlations between the IHC results (0, 1+ as negative, and 3+ as positive) and qRT-PCR and MLPA techniques were 0.743 and 0.831, respectively. Given the shortcomings of IHC analysis and greater correlations between MLPA, qRT-PCR, and FISH methods than IHC analysis alone with each of these three methods, we propose that MLPA and real-time PCR are good alternatives to IHC. However a suitable cut-off point for qRTPCR is a prerequisite for determining the exact status of HER2.

• 한국멀티미디어학회논문지
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• 제10권11호
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• pp.1483-1495
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• 2007

IEEE 802.11 기술 덕분에 학교와 대형 쇼핑몰을 비롯한 사무실, 병원, 역 등지에서도 무선 LAN을 통한 인터넷 접속이 가능하다. 본 논문은 무선 LAN에 현재 가장 많이 사용되는 2.4GHz 대역의 802.11b와 802.11g 프로토콜이 탑재된 액세스포인트(AP: Access Point)로부터 수신한 신호의 세기(RSSI: Received Signal Strength Indicator)를 판독할 수 있는 C# 라이브러리 함수를 제안한다. 위치기반서비스는 사용자의 현재 위치를 실시간으로 측정하여 현재 위치를 기반으로 길을 안내하거나, 현재 위치와 관련한 콘텐츠를 제공하는 등의 유용한 서비스를 제공한다. 옥내에서 위치기반서비스를 제공하려면 옥내에 있는 사용자의 위치를 판정하는 옥내측위가 반드시 선결되어야 한다. 옥내측위 기술로 적외선, 초음파, UDP 패킷의 신호세기 등을 이용하는 방법들이 소개된 바 있다. 이러한 방법들은 측위를 위한 특수 장비를 설비해야만 한다는 단점이 있다. 본 논문은 RSSI를 판독하는 라이브러리 함수를 제공할 뿐만 아니라 제공하는 함수를 이용한 옥내 측위 구현 예도 소개한다. 구현에 적용된 방법들은 이미 널리 알려진 K-NN(K Nearest Neighbors), 베이시안 방법 그리고 삼각측량법이다. K-NN 방법과 베이시안 방법은 일종의 지문방식인데, 지문방식은 준비단계와 실시간단계로 구성되며, 실시간 단계의 처리 과정은 처리속도가 빨라야만 한다. 본 논문은 실시간 단계의 속도를 개선하는 방법으로 판단나무 방법(Decision Tree Method)을 제안하고, 이러한 방법들의 성능을 실험적으로 평가한 결과를 소개한다.

• 대한영양사협회학술지
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• 제13권4호
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• pp.379-388
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• 2007

This study empirically examined the actual level of elementary school children's knowledge of nutrition and the extent of current nutrition education for the children through the use of textbooks. Two or three classes were sampled from each of six schools, respectively, in Gangneung; of the 562 questionnaires that were distributed, 537 were returned and used for analysis. Respondents were all sixth-graders, on average boys and girls were 153.02$\pm$8.19㎝ and 152.79$\pm$7.15㎝ in height and 45.27$\pm$10.32㎏ and 43.33$\pm$7.46㎏ in weight, respectively, which was consistent with others' research. Most children had two siblings and a working mother, considered that they were well off, and their mother prepared meals. Children regularly had breakfast and dinner, although more children had dinner than breakfast. As a whole, their knowledge of the main nutrients contained in foods was lower than their general knowledge of nutrition. There were significant differences in knowledge of the main nutrients contained in foods, with girls showing more knowledge than boys (p<0.01). Most of them learned about nutrition at school, followed by home. At school, Practical Technology classes taught them the most about nutrition. Although Physical Education classes were expected to teach about nutrition in a quantitative way, they accounted for just 4.7% of the overall knowledge. As for the children's understanding of nutrition education through use of a textbook at school, just 19% of the students gained a very good understanding. As for interest in nutrition education at school, 22.2% of the students had no interest, while girls were more likely to have their interest in nutrition education at school affected by knowledge of nutrition than boys. For both boys and girls, the most desired method of education was cooking practice. More research across subjects is necessary so that nutrition education concentrated on the curriculum for fifth-graders can be provided by stages from the lower grades. Since cooking practice or games were preferred, it is necessary to develop nutrition education methods to incite active interest rather than passive education.

• 디지털융복합연구
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• 제12권6호
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• pp.527-538
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• 2014

본 연구의 목적은 2008년에서 2012년에 대한간호협회 서울특별시간호사회에서 실시된 간호사 보수교육 자료를 분석하여 2012년 4월부터 전면시행 중인 의료인 면허신고제와 간호사 보수교육 운영의 발전을 위한 기초자료를 제공하고자 시도되었다. 2008년부터 2012년까지 5년간의 4,086건의 간호사 보수교육 프로그램을 이수한 165,759명의 자료를 SPSS 12.0을 이용하여 일반적 특성, 보수교육 프로그램, 면허취득경과기간을 기술통계, 면허취득경과기관에 따른 보수교육 프로그램의 차이를 t-Test, ANOVA, 상관관계로 분석하였다. 연구결과를 살펴보면, 2008년에 비해 2012년의 보수교육 이수자는 27.6% 증가하였고, 개발된 보수교육 프로그램수는 61.0% 증가하였다. 보수교육 이수자의 78.6%는 40세 미만이며, 89.5%가 병원에서 근무하고 있었다. 실시된 보수교육 내용 중 임상간호 내용이 65.6%로 가장 많았고, 보수교육 유형 중 82.6%가 기관개발교육이었다. 이수자의 면허취득경과연수에 따라 보수교육 프로그램, 보수교육 유형, 보수교육 내용의 참여에 유의한 차이를 보였으며 특히 면허취득경과연수가 길수록 근무지가 병원이 아닌 기타기관에 종사하는 대상자가 많았고 이수한 교육내용을 보면 지역보건, 직무역량이 증가하여 경력단계별 교육내용 요구도 파악 및 내용의 차별화가 필요함을 알 수 있다.

• 대한전자공학회논문지TC
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• 제43권10호
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• pp.90-97
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• 2006

본 논문에서는 cascode 구조에 shunt peaking 기술을 접목시킨 밀리미터파 광대역 amplifier를 설계 및 제작하였다. 밀리미터파 광대역 cascode amplifier의 설계 및 제작을 위해서 $0.1{\mu}m\;{\Gamma}-gate$ GaAs PHEMT와 CPW 및 passive library를 개발하였다. 제작된 PHEMT는 최대 전달 컨덕턴스는 346.3 mS/mm, 전류이득 차단 주파수 ($f_T$)는 113 GHz, 그리고 최대공진 주파수($f_{max}$)는 180 GHz의 특성을 갖고 있다. 설계된 cascode amplifier는 회로의 발진을 막기 위해서 저항과 캐패시터를 common-rate 소자의 드레인에 병렬로 연결하였다. 대역폭의 확장 및 gain의 평탄화를 위해 바이어스 단들에 short stub 및 common-source 소자와 common-gate 소자 사이에 보상 전송선로를 삽입하고 최적화하였으며, 입출력 단은 광대역 특성을 갖는 정합회로로 설계하였다. 제작된 cascode amplifier의 측정결과, cascode 구조에 shunt peaking 기술을 접목시킴으로써 대역폭을 확장 및 gain을 평탄화 시킬 수 있다는 것을 확인하였다. 3 dB 대역폭은 34.5 GHz ($19{\sim}53.5GHz$)로 광대역 특성을 얻었으며, 3 dB대역 내에서 평균 6.5 dB의 $S_{21}$ 이득 특성을 나타내었다.

• 한국조경학회지
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• 제33권4호
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• pp.129-142
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• 2005

Korea's pet-related society has been fast growing without the base and preparations of socio-cultural animal welfare. For the most part, Korea's current public parks, in particular, have a space structure in which a lot of friction between the general public who are not fond of dogs and dog owners in public places has been happening unavoidably. A lot of countries that are taking a lead role in animal welfare have built dog parte that the general public and dogs can enjoy together. This research starts with the realization that the concept of 'dog park' needs to be introduced in Korea as more and more Koreans own dogs and other pets. This research aims to provide guidance for dog park planning by drawing a dog park planning model and to promote basics for co-existence of dogs and people in a park and set in place animal welfare early and raise the level of awareness. Total 7 types of dog put 56 planning items including dog zone, dog playground, and agility, and a selective matrix by which it is possible to select essential recommendatory optional items by each type of dog park were drawn in this research. Overall there were the highest needs in separated area for dogs in park. A dog park planning model is designed as follows. 1) To select a dog park type that was introduced. 2) To set up facilities applicable in common and planning items desired in advance by each type. 3) To zone dog park areas by the priority order of planning items that were introduced and to position necessary facilities. 4) To plan program that should be were introduced. A dog park was expected to take some positive roles such as providing opportunities to socialize dogs, activating social communities, more effective park management by participating local community members and so on.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2010년도 하계학술대회 논문집
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• pp.11-11
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• 2010

Thin-film-transistors (TFTs) that can be deposited at low temperature have recently attracted lots of applications such as sensors, solar cell and displays, because of the great flexible electronics and transparent. Transparent and flexible transistors are being required that high mobility and large-area uniformity at low temperature [1]. But, unfortunately most of TFT structures are used to be $SiO_2$ as gate dielectric layer. The $SiO_2$ has disadvantaged that it is required to high driving voltage to achieve the same operating efficiency compared with other high-k materials and its thickness is thicker than high-k materials [2]. To solve this problem, we find lots of high-k materials as $HfO_2$, $ZrO_2$, $SiN_x$, $TiO_2$, $Al_2O_3$. Among the High-k materials, $Al_2O_3$ is one of the outstanding materials due to its properties are high dielectric constant ( ~9 ), relatively low leakage current, wide bandgap ( 8.7 eV ) and good device stability. For the realization of flexible displays, all processes should be performed at very low temperatures, but low temperature $Al_2O_3$ grown by sputtering showed deteriorated electrical performance. Further decrease in growth temperature induces a high density of charge traps in the gate oxide/channel. This study investigated the effect of growth temperatures of ALD grown $Al_2O_3$ layers on the TFT device performance. The ALD deposition showed high conformal and defect-free dielectric layers at low temperature compared with other deposition equipments [2]. After ITO was wet-chemically etched with HCl : $HNO_3$ = 3:1, $Al_2O_3$ layer was deposited by ALD at various growth temperatures or lift-off process. Amorphous InGaZnO channel layers were deposited by rf magnetron sputtering at a working pressure of 3 mTorr and $O_2$/Ar (1/29 sccm). The electrodes were formed with electron-beam evaporated Ti (30 nm) and Au (70 nm) bilayer. The TFT devices were heat-treated in a furnace at $300^{\circ}C$ and nitrogen atmosphere for 1 hour by rapid thermal treatment. The electrical properties of the oxide TFTs were measured using semiconductor parameter analyzer (4145B), and LCR meter.

• 전기전자학회논문지
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• 제2권2호
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• pp.278-284
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• 1998

본 논문에서는 HDTV 응용을 위한 10b 저전력 CMOS A/D 변환기 (analog-to-digital converter : ADC) 회로를 제안한다. 제안된 ADC의 전체 구조는 응용되는 시스템의 속도와 해상도 등의 사양을 고려하여 다단 파이프라인 구조가 적용되었다. 본 시스템이 갖는 회로적 특성은 다음과 같이 요약할 수 있다. 첫째, 전원전압의 변화에도 일정한 시스템 성능을 얻을 수 있는 바이어스 회로의 선택적 채널길이 조정기법을 제안한다. 둘째, 고속 2단 증폭기의 전력소모를 줄이기 위하여 증폭기가 사용되지 않는 동안 동작 전류 공급을 줄이는 전력소모 최적화 기법을 사용한다. 넷째, 다단 파이프라인 구조에서 최종단으로 갈수록 정확도 및 잡음 특성 등에서 여유를 얻을 수 있는 점을 고려한 캐패시터 스케일링 기법의 적용으로 면적 및 전력소모를 감소시킨다. 제안된 ADC는 0.8 um double-poly double-metal n-well CMOS 공정 변수를 사용하여 설계 및 제작되었고, 시제품 ADC의 성능 측정 결과는 Differential Nonlinearity (DNL) ${\pm}0.6LSB$, Integral Nonlinearity (INL) ${\pm}2.0LSB$ 수준이며, 전력소모는 3 V 및 40 MHz 동작시에는 119 mW, 5 V 및 50 MHz 동작시에는 320 mW로 측정되었다.

• 전기화학회지
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• 제11권4호
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• pp.268-272
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• 2008

본 연구에서는 $LiFePO_4$의 입자크기를 조절함으로써 우수한 전극특성을 나타낼 수 있도록 최적의 입자크기($50{\sim}100\;nm$)를 가지는 $LiFePO_4$ 양극 활물질을 전기방사법을 이용하여 합성하였다. XRD 분석결과 FeP, $Fe_2P$ 등의 불순물이 존재하지 않는 Pnma의 공간군을 가지는 잘 발달된 사방정 구조의 $LiFePO_4$가 합성됨을 확인하였으며, SEM 분석을 통하여 시료의 입자형태 및 크기를 관찰하였다. $0.1\;mA/cm^2$의 전류밀도와 $2.8{\sim}4.0\;V$의 전위영역에서 충 방전 테스트 수행시 135 mAh/g의 초기 방전용량을 나타내었으며, 50 싸이클 후에도 99.9% 이상의 용량 보존율을 보이는 우수한 싸이클 특성을 나타내었다.