• 대한통합의학회지
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• 제7권4호
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• pp.71-79
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• 2019

Purpose : Several studies suggest that smoking and vitamin D level is a risk factor of metabolic syndrome. The objective of this study is to evaluate the association between smoking status, vitamin D levels and the Korean adult male and female metabolic syndrome. Methods : We assessed 3796 participants aged 19 years and older from the Korean National Health and Nutritional Examination Survey 2013, 2014. Smoking statuses were collected from self-reported questionnaires. Subjects were divided into three categories: non-smokers, former smokers, and current smokers. Vitamin D was tested by Radioimmunoassay method and the value of serum 25-hydroxyvitamin D, which is an index of vitamin D status in the body, was used. The diagnosis of metabolic syndrome was made using criteria modified NCEP-ATP III. Logistic regression analysis was used to calculate odds ratios between smoking status, vitamin D levels, and metabolic syndrome. Results : The overall prevalence of metabolic syndrome was 23.0 % in men and 15.4 % in women. After adjusting for smoking, the odds ratio for men's metabolic syndrome in current smokers was 1.77 (95 % CI, 1.30~2.41), while for former smokers OR was 1.63 (95 % CI, 1.15~2.31) compared with nonsmokers. After adjustment vitamin D, the odds ratio for women's metabolic syndrome in vitamin D deficiency was 1.44 (95 % CI, 1.11~1.87) compared with normal. Conclusion : Smoking status was associated with an increased risk of metabolic syndrome in Korean adult males and decreased vitamin D level was associated with an increased risk of metabolic syndrome in Korean adult females.

• 디지털융복합연구
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• 제13권5호
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• pp.269-276
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• 2015

혈청 콜레스테롤 수준과 우울증의 연관성을 파악하고자 제4기 국민건강영양조사의 설문조사와 검사자료에서 우울증상군 834명과 대조군 3,317명을 추출하여 다변량 로지스틱 회귀분석으로 교차비를 계산하였다. 분석 결과 우울증상은 가족 월수입, 결혼상태, 교육기간, 직업, 흡연상태, 신체활동을 보정한 상태에서 저밀도지단백이 낮을 때(기준 높음) 교차비가 6.435배(95% CI)로 유의하게 높았다. 결론적으로 낮은 저밀도지단백은 우울 증상을 높일 위험이 높다는 것이 밝혀졌다. 그러나 아직 콜레스테롤에 의한 우울 기전이 아직 밝혀지지 않았기 때문에 추후 다양한 분야의 융복합 연구를 통하여 이를 밝힐 필요가 있다.

• Nutrition Research and Practice
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• 제9권5호
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• pp.539-546
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• 2015

BACKGROUND/OBJECTIVES: Women's bone health status is closely related with environmental factors and lifestyle factors. The purpose of this study is to evaluate the dietary risks of osteoporosis and osteopenia for Korean postmenopausal women. SUBJECTS/METHODS: The data from 1,433 subjects from the 2010 KNHANES were used and divided into three groups: normal, osteopenia, and osteoporosis group using bone mineral density (BMD). Nutrient intakes and food intake frequency were evaluated. Logistic regression analysis was applied to determine the odds ratios for osteoporosis and osteopenia. RESULTS: The RNI percentage of each nutrient and food intake frequency from 12 food groups decreased as bone mineral density status deteriorated. Risk for osteoporosis of low calcium (Ca) intake, under the EAR, showed an odds ratio of 2.13(95% CI; 1.26-3.61, P < 0.05). Higher intake frequency showed preventive effect from osteoporosis compared to lower intake frequency in such food group as dairy products (ORs 0.40, CI 0.21-0.75), beans (ORs 0.49, CI 0.29-0.83), seaweeds (ORs 0.55, CI 0.32-0.94), fish (ORs 0.56, CI 0.32-0.98), and fruits (ORs 0.42, CI 0.23-0.79) after adjusting for age. CONCLUSION: To prevent osteoporosis in later life, sufficient Ca intake and more frequent intakes of foods containing Ca such as dairy products, beans, fish, seaweeds, and fruits, which help in Ca absorption, should be stressed for Korean postmenopausal women.

• 한국식생활문화학회지
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• 제38권1호
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• pp.38-47
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• 2023

In this study, we aimed to explore whether eating alone is associated with mental health conditions in Korean adolescents. The data of 2,012 Korean adolescents aged 12-18 years were obtained from the Korea National Health and Nutrition Examination Survey 2015-2019. Participants were classified into three groups based on the frequency of eating alone: none (all meals with others); 1 meal/day alone; and ≥2 meals/day alone. Mental health conditions were assessed based on stress recognition, depressive symptoms, and suicidal ideation. Multivariable logistic regressions were employed to calculate the adjusted odds ratios (AORs) and 95% confidence intervals (CIs) of poor mental health conditions according to the frequency of eating alone. Adolescents who ate ≥2 meals/day alone had higher odds of stress recognition (AOR: 2.65, 95% CI: 1.94-3.63), depressive symptoms (AOR: 2.55, 95% CI: 1.47-4.42), and suicidal ideation (AOR: 2.53, 95% CI: 1.05-6.08) than those who ate all their meals with others. In addition, having breakfast or dinner alone increased the odds of stress recognition. Considering the continuous increase in the social phenomenon of eating alone, nutritional educations are needed to develop adolescents' ability to choose more nutritionally balanced and healthy meals when eating alone.

• 한국식생활문화학회지
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• 제38권5호
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• pp.293-303
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• 2023

This study aimed to determine the association between household types and healthy dietary practices among Korean adults. A cross-sectional analysis was performed using nationwide data on 23,488 participants from the 2017-2021 Korea National Health and Nutrition Examination Survey (KNHANES). Based on self-reported data, the participant household types were classified into single- and multi-person households. The adjusted odds ratios (AORs) and 95% confidence intervals (CIs) for healthy dietary practices according to household types were calculated by applying multivariable logistic regression analysis after adjusting for confounders. Of total, 11.21% and 88.79% were single- and multi-person households, respectively. Compared with individuals living in multi-person households, those in single-person households had lower odds of adhering to healthy dietary practices (AOR: 0.88, 95% CI: 0.79-0.98) and consuming adequate saturated fatty acids (<7% of energy) (AOR: 0.78, 95% CI: 0.69-0.88). In addition, men and individuals aged ≥65 years living in single-person households exhibited lower odds of consuming adequate saturated fatty acids and ≥500 g of fruit and vegetables per day than those in multi-person households. Single-person households often find it a challenge to practice a healthy diet. Hence, nutritional policies and educational support that help individuals living alone consume healthier diets are warranted.

• 대한한방내과학회지
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• 제30권3호
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• pp.510-524
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• 2009

Objective : This study was designed to find the correlation between Sasang Constitution and heart rate variability(HRV). Method : There were 665 subjects (280 men and 385 women), between 39 and 72 years old. in a rural community. Sasang Constitution was diagnosed by a Sasang constitutional specialist using PSSC (Phonetic System for Sasang Constitution), face and tongue photo and checkup-list. A structured-questionnaire was used to assess the general characteristics. HRV was recorded using SA-2000 (medi-core). HRV was assessed by time domain and by frequency domain analysis. Metabolic syndrome was defined on the basis of clustering of risk factors, when three or more of the following cardiovascular risk factors were included : blood pressure, fasting blood sugar, triglyceride HDL-cholesterol, and abdominal obesity (waist). Because of the skewness of the data, logarithmic transformation was performed on the absolute units of the spectral components of HRV, and the resulting logarithmic values and normalized units were compared between the groups by a logistic regression. The 95% confidence interval (CI) of the odds ratio was used and calculated from the data laid out for a cross sectional study. Results : 1. Odds ratios of Taeeumin and Soeumin in female adults below 60 years old were significantly lower than that of Soyangin in LF norm and LF/HF ratio. Odds ratios of Taeeumin and Soeumin in female adults below 60 years old were significantly higher than that of Soyangin in HF norm. 2. There was no significant correlation between HRV and Sasang Constitution in female adults from 60 years old and over. 3. There was no significant correlation between HRV and Sasang Constitution in male adults. Conclusion : There is a statistically significant correlation between the HRV and Sasang Constitution. There is a tendency of increase in the sympathetic activity in Soyangin. There is a tendency of decrease in the parasympathetic activity in Taeeumin and Soeumin.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9107-9112
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• 2014

Purpose: To investigate and study the relationship between the PLCE1 rs2274223 gene polymorphism and susceptibility to esophageal cancer by meta-analysis. Materials and Methods: The literature was searched in Wanfang, CNKI, PubMed, CBM, Web of Science, MEDLINE, EMBASE, Springer, Elsevier and Cochrane databases from the date of January $1^{st}$ 2004 to April $1^{st}$ 2014 to collect case-control studies on the PLCE1 polymorphism and susceptibility to esophageal cancer. For the population genotype distributions of both esophagus cancer and control groups, their odds ratios (ORs) and 95% confidence intervals (CIs) were taken as effect indexes. Disqualified studies were excluded. Odds ratios of PLCE1 rs2274223 genotype distributions in the group of patients with esophageal cancer and the group of healthy control were calculated. The metaanalysis software, RevMan5.0, was applied for heterogeneity test, pooled OR and 95% confidence intervals. Sensitivity analysis and publication bias were also explored. Results: A total of twelve case-control studies were included, covering a total of 9, 912 esophageal cancer cases and 13, 023 controls were included. The pooled odds ratio of PLCE1 rs2274223 genotype GA vs AA was 1.29 (95%CI=1.17~1.43), p<0.01, GG vs AA was 1.65 (95%CI=1.32~2.05), p<0.01, GG/GA vs AA was 1.30 (95%CI=1.16~1.46), p<0.01 and GG vs GA/AA was 1.48 (95%CI=1.22~1.80), p<0.01. The PLCE1 rs2274223 polymorphism was thus associated with risk of esophageal cancer in all genetic models. In the stratified analysis by ethnicity, and source of controls, no significantly increased risk was observed for white persons. There was no obvious publication bias detected. Conclusions: This meta-analysis showed there was a significantly association between PLCE1 rs2274223 polymorphism and esophageal cancer in yellow race populations. Due to some minor limitations, our findings should be confirmed in further studies.

• 한국환경보건학회지
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• 제37권3호
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• pp.182-192
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• 2011

Objectives: This study aims to identify the influential factors on the pulmonary function of targeted general residents in the areas surrounding Gwangyang Steel Mill. Methods: An PFT (Pulmonary Function Test) was conducted from May 2007 to November 2007 on 974 target residents (438 male, 536 female), including an exposed group (674 people) who resided within a radius of 5 km from Gwangyang Steel Mill in Gwangyang-si, Jeollanam-do and a control group (300 people) who resided outside a radius of 15 km. A survey related to personal characteristics, life habits, respiratory diseases and allergic symptoms, medical histories and living environments of the residents was also conducted to identify influential factors on pulmonary function. Results: As %$FEV_1$ and %FVC of the exposed group are 99.17% and 96.98%, respectively, and those of the control group are 105.47% and 101.91%, respectively, with the PFT values of the exposed group being lower than those of the control group (p<0.001), it turns out that the pollution in the industrial complex is likely to trigger a reduction in the pulmonary function of local residents. The odds ratio analysis result for asthma diagnosis history indicates that the odds ratios tend to be higher among surveyed residents who are living near above-average traffic volumes and are using beds, where it is statistically meaningful that especially the odds ratios are higher if the residences are closer to roads (p<0.01, CI=1.12-4.52). The factors that affect the FEV1 are identified as smoking, passive smoking, asthma diagnosis history, nasal congestion symptoms and allergic eye disease ($R^2$=0.154, p<0.001). The factors that affect the FVC are identified as smoking, passive smoking, asthma diagnosis history and allergic coryza ($R^2$=0.158, p<0.001). In addition, the analysis result for the relevance of air pollution levels to pulmonary function ($FEV_1$, FVC) shows that FEV1 and FVC tend to decrease as the concentration of $O_3$ increases. Conclusions: We believe that this study may provide preliminary data for the development of preventive measures for health effects on the residents and environmental health control measures for environmental pollution in the industrial complex area.

• Journal of Preventive Medicine and Public Health
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• 제33권2호
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• pp.208-214
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• 2000

이 연구는 노인 인구에서의 혈압과 인지기능과의 관련성을 조사하기 위하여 대구광역시 달성군에 거주하고 있는 만60-64세의 노인을 대상으로 1996년 4월 부터 9월까지 면담조사를 실시하였다. 최종분석에 이용된 대상자는 원래 목표 한 1,329명에서 932명으로 70.1%이었다. 인지기능의 측정은 한국판 간이정신상태검사법(MMSEK)을 사용하였으며, 인지기능장애는 점수가 23점 이하인 자로 정의 하였다. 혈압은 누운 상태에서 측 상완부를 휴대용 자동혈압계로 1회 측정하였다. 남자에서 인지기능에 대한 단일변수 지수회귀분석의 결과에서 수축기 혈압은 통계적으로 유의한 비차비를 보이는 혈압 범주는 없었다. 확장기 혈압은 80-89 mmHg를 기준으로 79 mmHg 이하, 90-94, 95 mmHg이상 모두 1보다 큰 비차비를 나타내었으며 특히 79mmHg 이하는 1.68(95% 신뢰구간 1.02-2.75)로 통계적인 유의성을 나타내었다. 여자에서 수축기 및 확장기 혈압 모두 통계적인 유의성을 나타낸 비차비는 없었다. 연령, 교육 수준, 흡연, 음주, 비교체중, 죽상경화증을 시사하는 질환, 고혈압 약 투약력 등의 공변수를 통제한 다변수 지수회귀분석에서 남자의 수축기 혈압은 단일변수 분석과 비교하여 비차비의 변화가 거의 없었으며 통계적인 유의성도 없었다. 확장기 혈압에서 기준 혈압 범주에 비교해서 79mmHg 이하는 비차비가 2.01(95% 신뢰구간 1.15-3.52)로 증가하였다. 여자에서 수축기 혈압은 단일변수 분석과 비교하여 거의 차이가 없었으며 통계적인 유의성도 없었으나, 반면에 확장기 혈압에서 기준 혈압 범주에 비교하여 79 mmHg 이하는 비차비가 0.72에서 0.57 (95%신뢰 구간 0.37-0.89)로 유의하게 증가하였다. 이들 결과는 혈압과 인지기능 장애와의 관계는 수축기 혈압보다는 확장기 혈압이 연관성을 나타내며 확장기 혈압과 인지기능 장애간의 관련성의 방향이 성별간에 차이를 나타내어 혈압과 인지기능사이에 좀더 복합적인 관계가 있음을 시사해 준다.

• 대한지역사회영양학회지
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• 제26권6호
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• pp.441-454
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• 2021

Objectives: This study investigated the association between the frequency and pattern of eating alone and the mental health status according to region in Korean adults. Methods: The data of 10,040 Korean adults aged ≥ 19 years from the Korea National Health and Nutrition Examination Survey (KNHANES) 2017 and 2019 were used. Participants were divided into 4 groups based on their frequency of eating alone: none (all meals together), 1, 2, and 3 meals/day alone. The regions were divided into urban and rural areas. Mental health status was assessed by stress recognition, depressive symptoms, and suicidal ideation. Multivariable logistic regressions were conducted to estimate the adjusted odds ratios (AORs) with 95% confidence intervals (CIs) on the association of the frequency and pattern of eating alone with poor mental health after controlling for covariates. Results: Among Korean adults, 74.1% ate more than one meal a day alone. Individuals having 3 meals a day alone tended to be less educated, single, single person households, or living in urban areas (all P < 0.05). In rural areas, those having 3 meals/day alone had higher odds of stress recognition (AOR: 1.55, 95% CI: 1.02-2.35) than those having all meals together. In urban areas, individuals eating alone 3 times/day had higher odds of stress recognition (AOR: 1.60, 95% CI: 1.31-1.96), depressive symptoms (AOR: 1.61, 95% CI: 1.23-2.12), and suicidal ideation (AOR: 2.14, 95% CI: 1.42-3.22) compared to those having all meals together. Urban residents having dinner alone had higher odds of depressive symptoms (AOR: 1.29, 95% CI: 1.05-1.58) and suicidal ideation (AOR: 1.66, 95% CI: 1.19-2.33) than those having dinner with others. Conclusions: Our findings showed that the frequency and patterns of eating alone were differentially associated with increased odds of poor mental health according to region of residence. Nutrition education is needed for those frequently eating alone, particularly those living in urban areas, to highlight the advantages of eating together and to ensure that they have balanced and healthy meals even if they eat alone.