• Korean Journal of Clinical Pharmacy
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• v.29 no.2
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• pp.101-108
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• 2019

Background: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases the occurrence of adverse events, such as bone marrow suppression. The aim of this study was to investigate the elimination of MTX at 24 and 48 hours. Methods: We retrospectively analyzed electronic medical records of ALL or NHL pediatric patients who received $5g/m^2$ MTX infusion over 24 hours (between June, 2012 and July, 2018) at the Yonsei University Health System, Korea. The delayed elimination of MTX concentrations was assessed with 100 or $150{\mu}M$ MTX at 24 hours, and 2 or $5{\mu}M$ at 48 hours. Results: Among the 85 MTX cycles administered, 23 cycles were classified in delayed elimination group, and 62 cycles showed normal elimination. At 24 hours, the delayed elimination group with MTX concentration > $100{\mu}M$ showed higher percentage than group with MTX concentration < $100{\mu}M$ (45.8% vs. 19.7%, p = 0.015). However, no differences were observed at $150{\mu}M$ MTX (p = 0.66). At 48 hours, the delayed elimination was higher than the normal elimination at both concentration baselines (p < 0.001 at $2{\mu}M$, p = 0.024 at $5{\mu}M$). Conclusions: MTX concentrations greater than $100{\mu}M$ show high probability of delayed elimination at 24 hours. When MTX levels are above normal, leucovorin and hydration regimens should be continued to prevent delayed elimination.

• Korean Journal of Construction Engineering and Management
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• v.20 no.2
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• pp.13-27
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• 2019

While temporary construction work applies to a temporary facility, it has a high use frequency during the construction period accounting for around 10% of the construction cost, it requires systematic management. However, construction inspection information of temporary construction work often has no special specification in the design documents and specification items, with the items on various standards also being formidable. Because of this, related inspection are likely to be performed inefficiently with a high probability for occurrence of human errors when quality inspection is conducted for the temporary construction work. In the present study, therefore, apply to the electronic operation support system capable of supporting implementation of inspection of providing related information for the contemporary construction work. To achieve this, a prototype is developed by using IDEF0 to identify information flow by process and organizing EPSS-based quality inspection Task. And then, efficiency of the quality inspection and information accessibility for temporary construction work are to be improved by verification method of Sample Project.

• Journal of Digital Convergence
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• v.17 no.4
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• pp.365-379
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• 2019

The purpose of this study is to investigate what factors affect cyber-delinquency after examining the previous research focusing on the general strain theory and the delinquency opportunity theory in the existing studies. And as adolescents move from middle school to high school, this study is intended to analyze what factors affect cyber-delinquency from a longitudinal perspective using KCYPS(Korea Child and Youth Panel Survey) elementary 4th grade fourth and seventh data. The adolescence cyber-delinquency probability of occurrence were analyzed through the panel logit fixed-effect model using STATA. And then the cyber-delinquency frequency of adolescents were analyzed through the panel tobit random-effect model. As a result of analyzing the factors affecting cyber-delinquency frequency, Adult media commitment, computer use time, and cell phone dependency increased cyber-delinquency frequency. On the other hand, among the parenting attitudes, the attitude of supervising attentively and adolescents' age-increasing decreased cyber-delinquency frequency.

• Journal of Korean Society on Water Environment
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• v.27 no.5
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• pp.634-645
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• 2011

A newly developed rainwater harvesting (RWH) system reliability model is evaluated for roof area of buildings in Haeundae District of Busan. RWH system is used to supply water for toilet flushing, back garden irrigation, and air cooling. This model is portable because it is based on a non-parametric precipitation generation algorithm using a markov chain. Precipitation occurrence is simulated using transition probabilities derived for each day of the year based on the historical probability of wet and dry day state changes. Precipitation amounts are selected from a matrix of historical values within a moving 30 day window that is centered on the target day. Then, the reliability of RWH system is determined for catchment area and tank volume ranges using synthetic precipitation data. As a result, the synthetic rainfall data well reproduced the characteristics of precipitation in Busan. Also the reliabilities of RWH system for each of demands were computed to high values. Furthermore, for study area using the RWH system, reduction efficiencies for rooftop runoff inputs to the sewer system and potable water demand are evaluated for 23%, 53%, respectively.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.459-467
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• 2021

This study examined the onset of adolescent delinquency through discrete-time survival analysis. Our analysis used data obtained from the Korean Children & Youth Panel Survey, and included 2,277 middle school students. The main analysis results are as follows. First, the hazard probability for the occurrence of delinquency was the highest at 16.6% in the second year of middle school, slightly decreased in the third year of middle school, but continued to increase as the overall grade increased. Second, adolescent psychological and emotional factors have significantly affected the onset of delinquency. Third, negative parenting methods had a significant impact on delinquency, but neglect was not significant. Fourth, having delinquent friends was an important factor affecting the status of delinquency. Fifth, among the school factors, adjustment of learning activities, adjustment of school rules, and adjustment of friendship relations influenced the status of delinquency, while the adjustment of teacher relations was not significant. As early intervention is important to prevent juvenile delinquency, education and support for establishing healthy relationships are needed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.10
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• pp.1254-1260
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• 2019

Recently, 5G cellular systems have been attracted great attention as a key enabler for Industry 4.0. In this paper, we propose a novel random access based on pilot-assisted opportunistic transmission to support internet-of-things (IoT) scenario in cellular networks. A key feature of our proposed scheme is to enable each of IoT devices to attempt opportunistic transmission of its data packet in Step 3 with randomly selected uplink pilot signal. Both the opportunistic transmission and the pilot randomization in Step 3 are effective to significantly mitigate the occurrence of packet collisions. We mathematically analyze our proposed scheme in terms of packet collision probability and uplink resource efficiency. Through simulations, we verify the validity of our analysis and evaluate the performance of our proposed scheme. Numerical results show that our proposed scheme outperforms other competitive schemes.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.2
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• pp.308-313
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• 2021

In this study, tweets about the 2019 Koreas-US DMZ Summit were collected along with a time sequence and analyzed by a sequential topic modeling method, Dynamic Topic Modeling(DTM). In microblogging services such as Twitter, unstructured data that mixes news and an opinion about a single event occurs at the same time on a large scale, and information and reactions are produced in the same message format. Therefore, to grasp a topic trend, the contextual meaning can be found only by performing pattern analysis reflecting the characteristics of sequential data. As a result of calculating the DTM after obtaining the topic coherence score and evaluating the Latent Dirichlet Allocation(LDA), 30 topics related to news reports and opinions were derived, and the probability of occurrence of each topic and keywords were dynamically evolving. In conclusion, the study found that DTM is a suitable model for analyzing the trend of integrated topics in a specific event over time.

• Journal of Korean Society of Water and Wastewater
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• v.35 no.6
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• pp.389-403
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• 2021

In this study, dual drainage system based runoff model was established for W-drainage area in G-si, and considering the various rainfall characteristics determined using Huff and Mononobe methods, the degree of flooding in the target area was analyzed and the risk was compared and analyzed through the risk matrix method. As a result, the Monobe method compared to the Huff method was analyzed to be suitable analysis for flooding of recent heavy rain, and the validity of the dynamic risk assessment considering the weight of the occurrence probability as the return period was verified through the risk matrix-based analysis. However, since the definition and estimating criteria of the flood risk matrix proposed in this study are based on the return period for extreme rainfall and the depth of flooding according to the results of applying the dual drainage model, there is a limitation in that it is difficult to consider the main factors which are direct impact on inland flooding such as city maintenance and life protection functions. In the future, if various factors affecting inland flood damage are reflected in addition to the amount of flood damage, the flood risk matrix concept proposed in this study can be used as basic information for preparation and prevention of inland flooding, as well as it is judged that it can be considered as a major evaluation item in the selection of the priority management area for sewage maintenance for countermeasures against inland flooding.

• Journal of the Korea Safety Management & Science
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• v.23 no.4
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• pp.23-29
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• 2021

The purpose of this study is to reduce the probability of occurrence of electric fires as a preemptive preventive measure, and to strengthen the capability of preventing electric fires by strengthening the cooperative function between electric fire-related departments and establishing a cooperative system. In this study, the general aspects of electric fires were identified by reviewing the literature such as ignition mechanisms of electric fires. And the major electrical fires that occurred in the last 10 years were classified into ignition factors (short circuit, overload/overcurrent, and earth leakage/ground fault) and ignition sources (wiring/wiring appliances, electrical equipment/household appliances). And the 4M technique was used to analyze the potential causes of ignition at the fire site and to suggest preventive measures. In the case In this study, out of 48 electrical fires in the past 10 years, 16 short-circuit fires, 3 overload/overcurrent fires, 3 short-circuit and earth fault fires, 16 fires in wiring/wiring appliances, and 10 fires in electrical equipment/home appliances classified as cases. And prevention measures were presented in terms of human, machine, media, and management by using the 4M technique. For the preemptive prevention of electric fires, strengthening the compulsory electrical safety inspection and making it mandatory to report when new or expanding electric facilities, charging a fee for electric safety inspection for detached houses and granting benefits subject to inspection completion, improvement of the electric safety voluntary inspection table and safety indications; It was suggested as a policy to organize and operate electrical safety inspection personnel in a two-person team (mixed), establish a close work cooperation system with related organizations, and strengthen electrical safety education and publicity.

• Journal of Environmental Science International
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• v.31 no.7
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• pp.543-553
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• 2022

The latest aerospace technology is important for the stable flight of a launch vehicle, but weather conditions on the day of launch are also one of the essential factors for successful launch campaign. If a launch vehicle is directly struck while preparing to take off from the launch pad on the day of launch or the electronic device are damaged by induced current during flight of the launch vehicle, this means launch failure and can lead to enormous national loss. Therefore, for a successful launch campaign, it is necessary to analyze the lightning detection characteristics of the Naro Space Center. In this study, the seasonal factors of the lightning that occurred over the Naro Space Center from 2003 to 2017, the influence of the polarity, and the correlation with the lightning intensity was confirmed. As a result, there was a high probability of intensive occurrence of multiple lightning strikes in summer, and a high proportion of positive (+) lightning strikes in winter. Lastly, in the distribution of the number of lightning strikes, an average of 2.0 to 2.5 negative (-) lightning strikes occurs in the coastal regions of the South and West Seas when one flash happens.