• Tuberculosis and Respiratory Diseases
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• v.84 no.2
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• pp.96-104
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• 2021

Background: Many chronic obstructive pulmonary disease (COPD) patients receiving monotherapy continue to experience symptoms, exacerbations and poor quality of life. This study aimed to assess the efficacy and safety of direct switch from once-daily tiotropium (TIO) 18 ㎍ to indacaterol/glycopyrronium (IND/GLY) 110/50 ㎍ once daily in COPD patients in Korea. Methods: This was a randomized, open-label, parallel group, 12-week trial in mild-to-moderate COPD patients who received TIO 18 ㎍ once daily for ≥12 weeks prior to study initiation. Patients aged ≥40 years, with predicted post-bronchodilator forced expiratory volume in 1 second (FEV₁) ≥50%, post-bronchodilator FEV₁/forced vital capacity <0.7 and smoking history of ≥10 pack-years were included. Eligible patients were randomized in a 1:1 ratio to either IND/GLY or TIO. The primary objective was to demonstrate superiority of IND/GLY over TIO in pre-dose trough FEV₁ at week 12. Secondary endpoints included transition dyspnea index (TDI) focal score, COPD assessment test (CAT) total score, and rescue medication use following the 12-week treatment, and safety assessment. Results: Of the 442 patients screened, 379 were randomized and 347 completed the study. IND/GLY demonstrated superiority in pre-dose trough FEV₁ versus TIO at week 12 (least squares mean treatment difference [Δ], 50 mL; p=0.013). Also, numerical improvements were observed with IND/GLY in the TDI focal score (Δ, 0.31), CAT total score (Δ, -0.81), and rescue medication use (Δ, -0.09 puffs/day). Both treatments were well tolerated by patients. Conclusion: A direct switch from TIO to IND/GLY provided improvements in lung function and other patient-reported outcomes with an acceptable safety profile in patients with mild-to-moderate airflow limitation.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.375-382
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• 2021

Adolescents with disabilities have unnatural behavior and language, which makes it difficult to use soft and flexible language and behavior, and lack of learning experience has limitations in not being free in mature behavioral communication. Eurhythmics musical rhythm elements were divided into time and space, power and weight, and balance and fluidity and reflected in teaching and learning so that adolescents with disabilities could have comfortable, creative, and original thoughts that bring about changes in thawing. In order to increase the effectiveness of education in the direction of observing the effect of improving self-esteem, communication, and creativity of adolescents with disabilities, the study guide applying the Eurhythmics rhythm element was fused with music education, art education, and physical education, and interviewed by selecting research participants. Based on the questionnaire, an observation method suitable for the study of adolescents with disabilities was conducted. As a result of the study, it was observed that the educational effect of the disabled youth was improved as a result of conducting the class by applying the Eurhythmics rhythm elements time and space, force and weight, balance and fluidity by integrating music, art, and physical education(line dance, playtime). Therefore, to supplement the limitations in this learning process, various educational methods applicable to the education of youth with disabilities, a support system that can reflect Eurhythmics education through physical play, and a method to properly compose various learning tools do.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.33 no.6
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• pp.383-390
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• 2021

The experiments in coastal engineering are very complex and a lot of components should be concerned. The experience has an important role in the successful execution. Hydraulic model experiments have been improved with the development of the wave generator and the advanced measuring apparatus. The hydraulic experiments have the advantage, that is, the stability of coastal structures and the hydraulic characteristics could be observed more intuitively rather than the numerical modelings. However, different experimental results can be drawn depending on the model scale, facilities, apparatus, and experimenters. In this study, two-dimensional hydraulic experiments were performed to suggest the guide of the test wave(random wave) generation, which is the most basic and important factor for the model test. The techniques for generating the random waves with frequency energy spectrum and the range for the incident wave height [(H_S)_M/(H_S)_T = 1~1.05] were suggested. The proposed guide for the test wave generation will contribute to enhancing the reliability of the experimental results in coastal engineering.

• International Journal of Computer Science & Network Security
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• v.22 no.3
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• pp.189-200
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• 2022

In today's digital world, smartphones and web-based applications have gained remarkable importance throughout the globe. These smart applications are playing a very significant role in maintaining a powerful business. As well as, they are helping a lot to expand these businesses via social networks. Social media networks such as Instagram, Facebook, Twitter, and LinkedIn are playing a prominent role to promote the companies. In the hospitality sector, most of the companies are running their hotel booking systems by utilizing mobile applications and a web-based infrastructure, but usability issues still exist. This study has been conducted specifically to tackle the usability issues of hotel booking systems and the best utilization of social networks to promote the business. TripAdvisor was selected as an authentic source for selecting those systems and two international hotels are selected for this study. The first step is to identify different hotel booking systems. In the second step, the user's satisfaction level was measured for the selected systems by performing the System Usability Scale (SUS, Quick & Dirty) approach. Additionally, by which source (social media or personal relations) they found these hotels. It is found that the SUS rating for both systems is below the acceptable level of usability. The Mean SUS for hotel 1 is found at 55.25 and 51.2 for hotel 2. The third step was to identify the user interface (UI) issues, and heuristic evaluation is performed for this. The experts identified the UI issues on the basis of their experience. The major issues were related to the visibility of system status, error prevention, flexibility and efficiency of use. Depending upon the identified issues, an interactive UI (prototype) for the selected web-based applications was proposed. This prototype is mainly based on the user's perspective. This prototype can be used for improving the UI of the selected systems which is based on the user's perspective. During the process of verifying the satisfaction level, it is revealed that the targeted audience is not able to use these systems efficiently and effectively. The reason behind this is the negligence of usability guidelines throughout the process of design and development of these hotel booking systems. Therefore, it is highly recommended that the usability of these systems should be evaluated and redesigned, based on expert opinions. It has also been observed that the reviews/ feedback of customers has spread a negative impact through social networks.

• 한국노년학
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• v.40 no.1
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• pp.33-49
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• 2020

This study was conducted to examine the latent classes in social exclusion and to analyse empirically the effects on the economic instability of old age by this type. And it also sought to look at whether the influence of old age anxiety varies with the subjective class consciousness of the elderly. Using the 14th data from the Korea General Social Survey (KGSS) in 2016, 1,041 adult males and females aged 18 years old were analyzed at the time of the survey. T-test, potential layer analysis (LCA), and multinomantic analysis of potential groups were conducted using the STATA14 and MPLUS 7 statistical programs. Finally, multi-regression analysis was performed to identify the moderate effect and effects among variables. According to the research, the types of social exclusion were three groups, followed by social exclusion group (49.3%), Multi-dimensional exclusion group (30.9%), and active social participation group (19.7%). The social exclusion group has the lowest possibility of economic, employment, and health exclusion, but the exclusion of formal and informal social activities seem to prominent, and the multi-dimensional exclusion group is more than 50% likely to experience exclusion in all areas. Active social participation are characterized by very active participation in informal social activities. By conducting multinominal logistic regression, it was observed that the social exclusion group included more young people than other groups, and that the multi-dimensional exclusion group included many elderly women without spouses. Finally, multiple regression analysis showed that social exclusion type interacts with subjective class consciousness and affects economic anxiety of old age.

• Journal of Korean Elementary Science Education
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• v.41 no.4
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• pp.627-641
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• 2022

This study aims to help elementary school teachers increase their knowledge about the changes in the positions of the sun and moon during the day and the first time the moon observation begins in the Earth and Space section of the Earth and the Moon. The survey questions were grouped into four categories, namely, textbook explanation, inquiry activities, achievement of learning goals, and other opinions. The perception of each question differed according to advanced science majors and teaching careers and experiences of this unit. In addition, understanding the diverse views of the participants using descriptive questions was possible. The study recruited 67 teachers working at an elementary school in Gyeonggi-do. The conclusion is as follows. First, the teachers exhibited similar positive and negative perceptions about the description of the textbook on the changes in the positions of the sun and moon during the day. Second, the study found that majority of teachers used alternative methods when guiding students regarding the change in the positions. This trend was not correlated with the sun and the moon, and the study observed no difference in advanced majors and teaching careers and experience of this unit. Third, the majority of teachers responded that they could achieve their learning goals through this learning. However, many teachers complained of various difficulties in guiding students about the lesson, and the majority alternative methods. The results demonstrated the perception of teachers that students can achieve learning goals through alternative methods without direct observation.

• Journal of the Korean Chemical Society
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• v.65 no.6
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• pp.441-454
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• 2021

In this study, pre-service science teachers' difficulties in teaching practice were investigated from the perspectives of pre-service teachers and cooperating teachers. Nine pre-service teachers who were attending a department of chemistry education at a college of education in Seoul and participated in teaching practice, and two of their cooperating teachers participated in the study. Teaching practice were observed, documentary data were collected, and interviews were conducted. The collected data were analyzed using analysis method of grounded theory. As results of the analysis, the pre-service teachers had difficulties in preparing and executing lessons which include experiments, because education related to experiments in middle and high schools was insufficient at the college of education and environments of cooperating school were unfamiliar to them. They had difficulties in encountering various responses from students in student-centered activities and tried to control students. Cooperating teachers did not provide specific assistance to ensure the autonomy of pre-service teachers, so that pre-service teachers suffered. Guiding science club activities was a meaningful experience to pre-service teachers, but it was a burden on both pre-service teachers and cooperating teachers. Educational implications of these findings were discussed.

• Journal of Korean Elementary Science Education
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• v.41 no.1
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• pp.30-43
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• 2022

In this study, elementary students' science communication competence was investigated based on the grammatical features expressed in their language-use in classroom discourse and science writings. The classes were designed to integrate the evidence-based reasoning framework and traditional learning cycle and were conducted on fifth graders in an elementary school. Eight elementary students' discourse data and writings were analyzed using lexico-grammatical resource analysis, which examined the discourse text's content and logical relations. The results revealed that the student language used in analyzing data, interpreting evidence, or constructing explanations did not precisely conform to the grammatical features in science language use. However, they provided examples of grammatical metaphors by nominalizing observed events in the classroom discourses and those of causal relations in their writings. Thus, elementary students can use science language grammatically from science language-use experiences through listening to a teacher's instructional discourses or recognizing the grammatical structures of science texts in workbooks. The opportunities in which elementary students experience the language-use model in science learning need to be offered to understand the appropriate language use in the epistemic context of evidence-based reasoning and learn literacy skills in science.

• Journal of the Daesoon Academy of Sciences
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• v.25_2
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• pp.1-43
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• 2015

Daesoonjinrihoe perceives that human suffering is caused not only by mental factors but also by the cosmic principle of Mutual Overcoming more fundamentally. The relationship influenced among all things in the universe is Mutual Beneficence and Mutual Overcoming. If these relations are properly cooperated in harmony, all things will reveal their energetic existence in a balanced state, however, if one side, particularly, Mutual Overcoming becomes excessive, indeed, it will cause trouble. That is, the sentient beings that are inclined to excessive Mutual Overcoming rather than indispensable Mutual Overcoming make grievances among themselves and cumulate them. In the end, heaven and earth lose its constant Way[常道], leading the sentient beings to all kinds of agonies. However, it may be a problem if every agony is depicted with Mutual Overcoming, that is, one single fixed frame, because Mutual Overcoming has to be interpreted diversely according to the circumstances. Thus, it is not possible to explain precisely about the agony if not understanding its spectrum. This study analyzed the ways how Daesoonjinrihoe explains the aspects of reasons and solutions to a variety of agonies. In the Supreme Scripture of Daesoonjinrihoe, the reasons for agony vary: first, it is caused by Mutual Overcoming of the cosmos itself, which is irrelevant to human beings. Secondly, man can be victimized because of Mutual Overcoming caused by man. Thirdly, there is a case of a victim who is damaged due to Mutual Overcoming caused by the other. Fourthly, man can be victimized because of Mutual Overcoming caused by someone else's unintended deeds. Fifthly, there is a case of man having agony in return when he, as a perpetrator, hurt others or resolve his inappropriate desires. Sixthly, man's deed unintendedly became a sin and have agony in return. Seventhly, man can be a self-perpetrator, conceiving vain desire, obsession and grievance. Eightly, there is a case of man having agony during enforcement of the law or practice of justice. Ninthly, man needs to endure agony during self-cultivation, enacting Reordering of the Universe(天地公事), ritual practice, promotion of fortune, and test. However, it is important to make sure that the reason for agony can interact with not only one but also diverse models in real situation. These nine models are included in the category of Mutual Overcoming; but, these cannot be classified in a single term, Mutual Overcoming because much information will be hidden, only to make it difficult to explain about agony more precisely. There are some characteristic observed in the concept of agony in Daesoonjinrihoe as follows: first, reasons for agony are caused by Mutual Overcoming although Mutual Overcoming can be interpreted differently according to the circumstances. Secondly, Daesoonjinrihoe makes a positive valuation for some agony. Thirdly, the solution to overcome a agony is brought to a conclusion, that is cultivation practice of Daesoonjinrihoe. Fourthly, the experience of agony and solution in Daesoonjinrihoe sometimes lie in the unit of family beyond individual. Fifthly, in the painful situation resulted from vain desire and obsession, Daesoonjinrihoe suggests a solution called Mutual Beneficence. That is, it emphasizes not only self-control but also active practice of considering others.

• Journal of the Korean Orthopaedic Association
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• v.54 no.5
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• pp.440-446
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• 2019

Purpose: This study assessed the treatment outcomes of myxoid liposarcoma in the extremities and investigate the prognostic factors. Materials and Methods: A total of 91 patients with myxoid liposarcoma (83 primary, 8 recurrent) between 2001 and 2015 were reviewed retrospectively. The local recurrence and metastasis after treatment were examined. The survival rates and prognostic factors affecting the survival were investigated. The mean follow-up was 84 months (range, 5-196 months). Results: The overall survival rates at 5-yr and 10-yr were 82% and 74%, respectively. The tumor size (p=0.04), round cell component (p<0.0001), grade (p=0.0002), and local recurrence (p=0.006) affected survival in primary patients. Extrapulmonary metastases were observed in 75.0% (18/24) of metastatic patients and the mean post metastasis survival was 26 months (range, 2-72 months) Conclusion: Myxoid liposarcoma developed mainly at the lower extremities. The tumor size, grade, component of round cells, and local recurrence were associated with the prognosis. The unique feature of extrapulmonary metastasis in myxoid liposarcoma should be noted in the treatment and follow-up.